Barbara W Bernstein

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi Neuronal guidance: a redox signal involving Mical
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Curr Biol 20:R360-2. 2010
  2. ncbi ADF/cofilin: a functional node in cell biology
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Trends Cell Biol 20:187-95. 2010
  3. ncbi Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Am J Physiol Cell Physiol 291:C828-39. 2006
  4. ncbi In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups
    Hui Chen
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523-1870, USA
    Biochemistry 43:7127-42. 2004
  5. ncbi Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Neurosci 32:6670-81. 2012
  6. ncbi Production and use of replication-deficient adenovirus for transgene expression in neurons
    L S Minamide
    Department of Biochemistry and Molecular Biology, Program in Molecular, Cellular and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:387-416. 2003
  7. ncbi Actin-ATP hydrolysis is a major energy drain for neurons
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and the Program in Molecular, Cellular, and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    J Neurosci 23:1-6. 2003
  8. ncbi Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells
    Mitra N Jha
    Department of Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523-1673, USA
    Radiat Res 157:26-31. 2002
  9. ncbi ADF/cofilin
    James R Bamburg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Curr Biol 18:R273-5. 2008
  10. ncbi Dissection and culturing of chick ciliary ganglion neurons: a system well suited to synaptic study
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and Program in Molecular, Cellular, and Integrative Neurosciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:37-50. 2003

Collaborators

  • James R Bamburg
  • Hui Chen
  • L S Minamide
  • Mitra N Jha
  • Judith M Sneider
  • Laurie S Minamide
  • Judith A Boyle
  • P D Sarmiere
  • J A Gonzalez
  • O Wiggan
  • A E Shaw
  • M T Maloney
  • J M Sneider
  • Joel S Bedford

Detail Information

Publications11

  1. ncbi Neuronal guidance: a redox signal involving Mical
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Curr Biol 20:R360-2. 2010
    ..Recent work now shows that Mical's ability to bind actin filaments and destabilize them in a NADPH-dependent manner is responsible for semaphorin 1a's effects...
  2. ncbi ADF/cofilin: a functional node in cell biology
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Trends Cell Biol 20:187-95. 2010
    ..We argue that this ability to respond to physiological changes by modulating those same changes makes the ADF/cofilin protein family a homeostatic regulator or 'functional node' in cell biology...
  3. ncbi Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Am J Physiol Cell Physiol 291:C828-39. 2006
    ....
  4. ncbi In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups
    Hui Chen
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523-1870, USA
    Biochemistry 43:7127-42. 2004
    ..The ADF-like group has higher affinities for Mg(2+)-ATP-G-actin than the cofilin-like group and a greater pH-dependent depolymerizing activity...
  5. ncbi Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Neurosci 32:6670-81. 2012
    ..Oligomerization of cofilin in cells represents one more mechanism for regulating the actin dynamizing activity of cofilin and probably underlies synaptic loss...
  6. ncbi Production and use of replication-deficient adenovirus for transgene expression in neurons
    L S Minamide
    Department of Biochemistry and Molecular Biology, Program in Molecular, Cellular and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:387-416. 2003
    ..This chapter describes simplifications in the protocols for making recombinant adenoviruses and their use in expressing transgenes in primary neurons of several different types...
  7. ncbi Actin-ATP hydrolysis is a major energy drain for neurons
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and the Program in Molecular, Cellular, and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    J Neurosci 23:1-6. 2003
    ....
  8. ncbi Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells
    Mitra N Jha
    Department of Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523-1673, USA
    Radiat Res 157:26-31. 2002
    ..Thus it is likely that caffeine is eliminating the radiation-induced G2-phase delay through a Ca(++)-independent mechanism, such as the inhibition of a cell cycle-regulating kinase...
  9. ncbi ADF/cofilin
    James R Bamburg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Curr Biol 18:R273-5. 2008
  10. ncbi Dissection and culturing of chick ciliary ganglion neurons: a system well suited to synaptic study
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and Program in Molecular, Cellular, and Integrative Neurosciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:37-50. 2003
    ..However, they are ideally suited for studies based on single-cell observation, particularly investigation of presynaptic mechanisms using fluorescence microscopy...
  11. ncbi A proposed mechanism for cell polarization with no external cues
    Barbara W Bernstein
    Department of Biochemistry, Colorado State University, Fort Collins, CO 80523-1870, USA
    Cell Motil Cytoskeleton 58:96-103. 2004