Barbara W Bernstein

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. doi request reprint Neuronal guidance: a redox signal involving Mical
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Curr Biol 20:R360-2. 2010
  2. pmc ADF/cofilin: a functional node in cell biology
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Trends Cell Biol 20:187-95. 2010
  3. ncbi request reprint Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Am J Physiol Cell Physiol 291:C828-39. 2006
  4. ncbi request reprint In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups
    Hui Chen
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    Biochemistry 43:7127-42. 2004
  5. pmc A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons
    Jianjie Mi
    Department of Biochemistry and Molecular Biology, and Molecular, Cellular and Integrative Neuroscience Program, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e83609. 2013
  6. pmc Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Neurosci 32:6670-81. 2012
  7. ncbi request reprint Production and use of replication-deficient adenovirus for transgene expression in neurons
    L S Minamide
    Department of Biochemistry and Molecular Biology, Program in Molecular, Cellular and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:387-416. 2003
  8. ncbi request reprint Actin-ATP hydrolysis is a major energy drain for neurons
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and the Program in Molecular, Cellular, and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    J Neurosci 23:1-6. 2003
  9. ncbi request reprint Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells
    Mitra N Jha
    Department of Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523 1673, USA
    Radiat Res 157:26-31. 2002
  10. doi request reprint ADF/cofilin
    James R Bamburg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Curr Biol 18:R273-5. 2008

Collaborators

  • James R Bamburg
  • Jianjie Mi
  • Laurie S Minamide
  • Hui Chen
  • L S Minamide
  • Mitra N Jha
  • Chi W Pak
  • Keifer P Walsh
  • Thomas B Kuhn
  • Alisa E Shaw
  • Judith M Sneider
  • Judith A Boyle
  • M T Maloney
  • P D Sarmiere
  • J A Gonzalez
  • O Wiggan
  • A E Shaw
  • J M Sneider
  • Joel S Bedford

Detail Information

Publications12

  1. doi request reprint Neuronal guidance: a redox signal involving Mical
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Curr Biol 20:R360-2. 2010
    ..Recent work now shows that Mical's ability to bind actin filaments and destabilize them in a NADPH-dependent manner is responsible for semaphorin 1a's effects...
  2. pmc ADF/cofilin: a functional node in cell biology
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Trends Cell Biol 20:187-95. 2010
    ..We argue that this ability to respond to physiological changes by modulating those same changes makes the ADF/cofilin protein family a homeostatic regulator or 'functional node' in cell biology...
  3. ncbi request reprint Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons
    Barbara W Bernstein
    Dept of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Am J Physiol Cell Physiol 291:C828-39. 2006
    ....
  4. ncbi request reprint In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups
    Hui Chen
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    Biochemistry 43:7127-42. 2004
    ..The ADF-like group has higher affinities for Mg(2+)-ATP-G-actin than the cofilin-like group and a greater pH-dependent depolymerizing activity...
  5. pmc A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons
    Jianjie Mi
    Department of Biochemistry and Molecular Biology, and Molecular, Cellular and Integrative Neuroscience Program, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e83609. 2013
    ..CofilinR21Q-mRFP is a genetically encoded rod reporter that is useful in live cell imaging studies of induced rod formation, including rod dynamics, and kinetics of rod elimination. ..
  6. pmc Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Neurosci 32:6670-81. 2012
    ..Oligomerization of cofilin in cells represents one more mechanism for regulating the actin dynamizing activity of cofilin and probably underlies synaptic loss...
  7. ncbi request reprint Production and use of replication-deficient adenovirus for transgene expression in neurons
    L S Minamide
    Department of Biochemistry and Molecular Biology, Program in Molecular, Cellular and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:387-416. 2003
    ..This chapter describes simplifications in the protocols for making recombinant adenoviruses and their use in expressing transgenes in primary neurons of several different types...
  8. ncbi request reprint Actin-ATP hydrolysis is a major energy drain for neurons
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and the Program in Molecular, Cellular, and Integrative Neuroscience, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    J Neurosci 23:1-6. 2003
    ....
  9. ncbi request reprint Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells
    Mitra N Jha
    Department of Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523 1673, USA
    Radiat Res 157:26-31. 2002
    ..Thus it is likely that caffeine is eliminating the radiation-induced G2-phase delay through a Ca(++)-independent mechanism, such as the inhibition of a cell cycle-regulating kinase...
  10. doi request reprint ADF/cofilin
    James R Bamburg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Curr Biol 18:R273-5. 2008
  11. ncbi request reprint Dissection and culturing of chick ciliary ganglion neurons: a system well suited to synaptic study
    Barbara W Bernstein
    Department of Biochemistry and Molecular Biology and Program in Molecular, Cellular, and Integrative Neurosciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Methods Cell Biol 71:37-50. 2003
    ..However, they are ideally suited for studies based on single-cell observation, particularly investigation of presynaptic mechanisms using fluorescence microscopy...
  12. ncbi request reprint A proposed mechanism for cell polarization with no external cues
    Barbara W Bernstein
    Department of Biochemistry, Colorado State University, Fort Collins, CO 80523 1870, USA
    Cell Motil Cytoskeleton 58:96-103. 2004