J T Belisle

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
    J T Belisle
    Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Science 276:1420-2. 1997
  2. ncbi request reprint The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis
    M L Schaeffer
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 274:31625-31. 1999
  3. pmc Definition of the full extent of glycosylation of the 45-kilodalton glycoprotein of Mycobacterium tuberculosis
    K M Dobos
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    J Bacteriol 178:2498-506. 1996
  4. pmc The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol
    A E Belanger
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Proc Natl Acad Sci U S A 93:11919-24. 1996
  5. ncbi request reprint Determination of the pathway for rhamnose biosynthesis in mycobacteria: cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase
    Y Ma
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Microbiology 143:937-45. 1997
  6. ncbi request reprint Identification of putative exported/secreted proteins in prokaryotic proteomes
    M T Saleh
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado, USA
    Gene 269:195-204. 2001
  7. ncbi request reprint The application of proteomics in defining the T cell antigens of Mycobacterium tuberculosis
    B A Covert
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Proteomics 1:574-86. 2001
  8. pmc A genetic mechanism for deletion of the ser2 gene cluster and formation of rough morphological variants of Mycobacterium avium
    T M Eckstein
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523 1677, USA
    J Bacteriol 182:6177-82. 2000
  9. ncbi request reprint Tuberculosis vaccine development: recent progress
    I M Orme
    Mycobacteria Research Laboratories, Dept of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Trends Microbiol 9:115-8. 2001
  10. pmc Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis
    K M Dobos
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Infect Immun 63:2846-53. 1995

Collaborators

  • D Chatterjee
  • M L Schaeffer
  • Y Ma
  • V D Vissa
  • I M Orme
  • P J Brennan
  • M T Saleh
  • K M Dobos
  • B A Covert
  • T M Eckstein
  • J M Inamine
  • A E Belanger
  • K H Khoo
  • J S Spencer
  • M Fillon
  • D N McMurray
  • M L Lambert
  • G S Besra
  • K Mikusova
  • M E Ford
  • K M Swiderek
  • K Swiderek

Detail Information

Publications10

  1. ncbi request reprint Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
    J T Belisle
    Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Science 276:1420-2. 1997
    ..Furthermore, the use of an antagonist (6-azido-6-deoxy-alpha, alpha'-trehalose) of this activity demonstrates that these proteins are essential and potential targets for new antimycobacterial drugs...
  2. ncbi request reprint The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis
    M L Schaeffer
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 274:31625-31. 1999
    ..smegmatis overexpressing the pimB gene were used in cell-free assays to show that PimB catalyzes the formation of triacylphosphatidylinositol dimannoside from GDP-mannose and triacylphosphatidylinositol monomannoside...
  3. pmc Definition of the full extent of glycosylation of the 45-kilodalton glycoprotein of Mycobacterium tuberculosis
    K M Dobos
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    J Bacteriol 178:2498-506. 1996
    ....
  4. pmc The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol
    A E Belanger
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Proc Natl Acad Sci U S A 93:11919-24. 1996
    ....
  5. ncbi request reprint Determination of the pathway for rhamnose biosynthesis in mycobacteria: cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase
    Y Ma
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Microbiology 143:937-45. 1997
    ..coli with pBluescript KS(-) containing the rfbA gene from M. tuberculosis. Analysis of enzyme extracts prepared from this transformant revealed an 11-fold increase in alpha-D-Glc-1-P thymidylyltransferase activity...
  6. ncbi request reprint Identification of putative exported/secreted proteins in prokaryotic proteomes
    M T Saleh
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado, USA
    Gene 269:195-204. 2001
    ....
  7. ncbi request reprint The application of proteomics in defining the T cell antigens of Mycobacterium tuberculosis
    B A Covert
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Proteomics 1:574-86. 2001
    ..However 17 of these proteins were novel T cell antigens. The data presented demonstrate that proteomics offers a rapid and facile approach for elucidation of immunodominant T cell antigens of pathogenic bacteria...
  8. pmc A genetic mechanism for deletion of the ser2 gene cluster and formation of rough morphological variants of Mycobacterium avium
    T M Eckstein
    Mycobacteria Research Laboratories, Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523 1677, USA
    J Bacteriol 182:6177-82. 2000
    ..and provides further evidence that homologous recombination between insertion sequence elements can be a primary determinant of genome plasticity in these bacteria...
  9. ncbi request reprint Tuberculosis vaccine development: recent progress
    I M Orme
    Mycobacteria Research Laboratories, Dept of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Trends Microbiol 9:115-8. 2001
    ..The results to date lead us to be optimistic that new candidate vaccines could soon be considered for evaluation in clinical trials...
  10. pmc Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis
    K M Dobos
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Infect Immun 63:2846-53. 1995
    ..This report establishes that true, O-glycosylated proteins exist in mycobacteria...