R V Anthony

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint Assessing gene function in the ruminant placenta
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Soc Reprod Fertil Suppl 67:119-31. 2010
  2. pmc The chemokine receptor CXCR4 and its ligand CXCL12 are activated during implantation and placentation in sheep
    Ryan L Ashley
    Department of Animal and Range Sciences, New Mexico State University, Las Cruces, New Mexico, USA
    Reprod Biol Endocrinol 9:148. 2011
  3. pmc Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation
    Katie J Torley
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Reprod Biol Endocrinol 9:2. 2011
  4. ncbi request reprint Ribonucleic acid interference: a new approach to the in vivo study of gene function
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins 80523 1683, USA
    J Anim Sci 85:E18-9. 2007
  5. ncbi request reprint Ruminant models of prenatal growth restriction
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1683, USA
    Reprod Suppl 61:183-94. 2003
  6. ncbi request reprint Transcriptional regulation in the placenta during normal and compromised fetal growth
    R V Anthony
    Department of Physiology, ARBL Foothills Campus, Colorado State University, Fort Collins, CO 80523 1683, U S A
    Biochem Soc Trans 29:42-8. 2001
  7. pmc Specificity protein-1 and -3 trans-activate the ovine placental lactogen gene promoter
    K M Jeckel
    Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1683, USA
    Mol Cell Endocrinol 307:118-24. 2009
  8. doi request reprint Effects of ractopamine and trenbolone acetate implants with or without estradiol on growth performance, carcass characteristics, adipogenic enzyme activity, and blood metabolites in feedlot steers and heifers
    T C Bryant
    Department of Animal Sciences, Colorado State University, Fort Collins 80523 1171, USA
    J Anim Sci 88:4102-19. 2010
  9. doi request reprint Effects of overfeeding naturally-mated adolescent ewes on maternal, fetal, and postnatal lamb growth
    R K Peel
    Department of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Anim Sci 90:3698-708. 2012
  10. ncbi request reprint Novel activator protein-2alpha splice-variants function as transactivators of the ovine placental lactogen gene
    S W Limesand
    Animal Reproduction and Biotechnology Laboratory, Department of Physiology, Colorado State University, Fort Collins, CO 80523 1683, USA
    Eur J Biochem 268:2390-401. 2001

Research Grants

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Assessing gene function in the ruminant placenta
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Soc Reprod Fertil Suppl 67:119-31. 2010
    ..While this technology is still being developed, it may provide an efficient approach to assess specific gene function in the ruminant placenta...
  2. pmc The chemokine receptor CXCR4 and its ligand CXCL12 are activated during implantation and placentation in sheep
    Ryan L Ashley
    Department of Animal and Range Sciences, New Mexico State University, Las Cruces, New Mexico, USA
    Reprod Biol Endocrinol 9:148. 2011
    ..The objectives of the current study were to determine if CXCL12 and CXCR4 were upregulated in: endometrium from pregnant compared to non-pregnant ewes and in, conceptuses, cotyledons, caruncles and intercaruncular tissue...
  3. pmc Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation
    Katie J Torley
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Reprod Biol Endocrinol 9:2. 2011
    ..We postulate these expression patterns are regulated by small non-coding RNAs called microRNAs (miRNAs). The aim of this study was to identify the expression of miRNAs in mammalian fetal gonads using sheep as a model...
  4. ncbi request reprint Ribonucleic acid interference: a new approach to the in vivo study of gene function
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins 80523 1683, USA
    J Anim Sci 85:E18-9. 2007
    ..This technology may become the method of choice for defining gene function in livestock...
  5. ncbi request reprint Ruminant models of prenatal growth restriction
    R V Anthony
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1683, USA
    Reprod Suppl 61:183-94. 2003
    ..Although all of these sheep models are capable of inducing fetal growth restriction, the degree of restriction is variable. This review compares these sheep models of IUGR with the characteristics of human IUGR...
  6. ncbi request reprint Transcriptional regulation in the placenta during normal and compromised fetal growth
    R V Anthony
    Department of Physiology, ARBL Foothills Campus, Colorado State University, Fort Collins, CO 80523 1683, U S A
    Biochem Soc Trans 29:42-8. 2001
    ..Examination of transcriptional regulation in normal and compromised pregnancies will provide additional insight in this area...
  7. pmc Specificity protein-1 and -3 trans-activate the ovine placental lactogen gene promoter
    K M Jeckel
    Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1683, USA
    Mol Cell Endocrinol 307:118-24. 2009
    ..In conclusion, these results indicate that Sp1 and Sp3 are capable of interacting with FP6 of the oPL gene proximal promoter and function to enhance its transactivation...
  8. doi request reprint Effects of ractopamine and trenbolone acetate implants with or without estradiol on growth performance, carcass characteristics, adipogenic enzyme activity, and blood metabolites in feedlot steers and heifers
    T C Bryant
    Department of Animal Sciences, Colorado State University, Fort Collins 80523 1171, USA
    J Anim Sci 88:4102-19. 2010
    ..These data suggest that the effects of implant and RAC on growth and carcass traits are independent and that USDA quality grade and marbling score can differ significantly among carcasses with similar calculated EBF values...
  9. doi request reprint Effects of overfeeding naturally-mated adolescent ewes on maternal, fetal, and postnatal lamb growth
    R K Peel
    Department of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Anim Sci 90:3698-708. 2012
    ..In conclusion, excess nutrition during gestation in naturally-mated adolescent ewes did not affect birth weight or postnatal performance of offspring...
  10. ncbi request reprint Novel activator protein-2alpha splice-variants function as transactivators of the ovine placental lactogen gene
    S W Limesand
    Animal Reproduction and Biotechnology Laboratory, Department of Physiology, Colorado State University, Fort Collins, CO 80523 1683, USA
    Eur J Biochem 268:2390-401. 2001
    ..These data indicate the presence of new mammalian AP-2alpha splice-variants that augment transactivation of the oPL gene in ovine chorionic binucleate cells...
  11. doi request reprint Effect of dietary supplemental vitamin A concentration on performance, carcass merit, serum metabolites, and lipogenic enzyme activity in yearling beef steers
    T C Bryant
    Department of Animal Sciences, Colorado State University, Fort Collins, USA
    J Anim Sci 88:1463-78. 2010
    ....
  12. ncbi request reprint Structure and transcriptional regulation of the ovine placental lactogen gene
    R Liang
    Animal Reproduction and Biotechnology Laboratory, Department of Physiology, Colorado State University, Fort Collins, CO, USA
    Eur J Biochem 265:883-95. 1999
    ..However, our data indicate that regulation of oPL also results from novel cis-acting elements...
  13. ncbi request reprint Altered placental and fetal expression of IGFs and IGF-binding proteins associated with intrauterine growth restriction in fetal sheep during early and mid-pregnancy
    Barbra de Vrijer
    Department of Obstetrics and Gynecology, Division of Obstetrics and Prenatal Medicine, Erasmus University Medical Center, 3000 CB Rotterdam, The Netherlands
    Pediatr Res 60:507-12. 2006
    ..These data suggest that changes in placental IGF expression in early and mid gestation may predispose the pregnancy to placental insufficiency, resulting in inadequate substrate supply to the developing fetus later in gestation...
  14. pmc The relationship between transplacental O2 diffusion and placental expression of PlGF, VEGF and their receptors in a placental insufficiency model of fetal growth restriction
    Timothy R H Regnault
    Department of Pediatrics, Division of Perinatal Medicine, University of Colorado Health Sciences Center, Aurora, CO 80010, USA
    J Physiol 550:641-56. 2003
    ..Furthermore, these data suggest that an increased transplacental gradient of oxygen generates changes in angiogenic growth factors, which may underline the pathophysiology of the post-placental hypoxic FGR...
  15. ncbi request reprint Fetal hypertension and abnormal Doppler velocimetry in an ovine model of intrauterine growth restriction
    Henry L Galan
    Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center, Denver, Colo, USA
    Am J Obstet Gynecol 192:272-9. 2005
    ..Our objective was to test the hypothesis that systemic blood pressure (BP) is increased above normal in intrauterine growth restricted (IUGR) fetal lambs with elevated umbilical artery (UmA) Doppler indices...
  16. ncbi request reprint Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction
    Amy S Erickson Hagen
    Department of Biomedical Sciences, Colorado State University, Fort Collins 80523, USA
    Pediatr Res 58:1228-32. 2005
    ....
  17. ncbi request reprint Differential expression of placental and vascular endothelial nitric oxide synthase in an ovine model of fetal growth restriction
    Juan A Arroyo
    Division of Perinatal Medicine, Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Obstet Gynecol 195:771-7. 2006
    ....
  18. doi request reprint An animal model of placental insufficiency-induced intrauterine growth restriction
    James S Barry
    Perinatal Research Center, Department of Pediatrics, University of Colorado Health Sciences Center, Aurora, CO 80045, USA
    Semin Perinatol 32:225-30. 2008
    ..This review will focus on one sheep model, used to examine the impact of placental insufficiency-induced IUGR on oxygen and nutrient transport and utilization...
  19. pmc Decreased placental X-linked inhibitor of apoptosis protein in an ovine model of intrauterine growth restriction
    Juan A Arroyo
    Department of Obstetrics and Gynecology, Division of Perinatal Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Obstet Gynecol 199:80.e1-8. 2008
    ..The objective of the study was to assess placental apoptosis at both midgestation and near term in an ovine model of placental insufficiency (PI) and intrauterine growth restriction (IUGR)...
  20. ncbi request reprint Ontogeny of endothelial nitric oxide synthase mRNA in an ovine model of fetal and placental growth restriction
    Bradley T Ziebell
    Division of Perinatal Medicine, Department of Obstetrics and Gynecology, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
    Am J Obstet Gynecol 197:420.e1-5. 2007
    ..To determine: 1) placental eNOS mRNA concentration across gestation in normal ovine pregnancy and in an ovine model of intrauterine growth restriction (IUGR), and 2) placental eNOS protein concentration in early ovine pregnancy...
  21. ncbi request reprint The expression of ovine placental lactogen, StAR and progesterone-associated steroidogenic enzymes in placentae of overnourished growing adolescent ewes
    Richard G Lea
    School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK
    Reproduction 133:785-96. 2007
    ..Restricted placental growth and reduced biosynthesis may account for reduced progesterone in day 130 H+IUGR ewes...
  22. ncbi request reprint Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein
    Joao F Oliveira
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Endocrinology 149:1252-9. 2008
    ..It is concluded that uterine vein releases IFN-tau, which induces ISG in extrauterine tissues such as the CL during the time of maternal recognition of pregnancy...
  23. ncbi request reprint Puralpha, a single-stranded deoxyribonucleic acid binding protein, augments placental lactogen gene transcription
    Sean W Limesand
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 1683, USA
    Mol Endocrinol 18:447-57. 2004
    ..This study identified a previously undefined cis-element, which interacts with Pur alpha to augment PL gene transcription...
  24. ncbi request reprint The IGF-II-deficient placenta: aspects of its function
    Timothy R H Regnault
    Dept of Pediatrics, Division of Perinatal Medicine, University of Colorado Health Sciences Center, 13243 East 23rd Avenue, Aurora, CO 80010, USA
    Trends Endocrinol Metab 13:410-2. 2002

Research Grants1

  1. Prenatal Hypoxia and Development of Insulin Resistance
    RUSSELL ANTHONY; Fiscal Year: 2006
    ..g. insulin receptor, IRS's, PIS kinase, protein kinase B, glycogen synthase kinase and glycogen synthase), in liver. These studies will provide insight in to the role fetal hypoxia alone may play in the development of Syndrome X. ..