J L Sartin

Summary

Affiliation: College of Veterinary Medicine
Country: USA

Publications

  1. ncbi request reprint Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849 5520, USA
    J Anim Sci 81:1546-51. 2003
  2. doi request reprint Central role of the melanocortin-4 receptors in appetite regulation after endotoxin
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    J Anim Sci 86:2557-67. 2008
  3. ncbi request reprint Reduced growth of calves and its reversal by use of anabolic agents
    J L Sartin
    Departments of Anatomy, Physiology and Pharmacology, Alabama Agricultural Experiment Station, Auburn University, Auburn, AL 36849 5518, USA
    Domest Anim Endocrinol 19:85-92. 2000
  4. ncbi request reprint Effect of intracerebroventricular orexin-B on food intake in sheep
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849 5518, USA
    J Anim Sci 79:1573-7. 2001
  5. ncbi request reprint Melanocortin-4 receptor in sheep: a potential site for therapeutic intervention in disease models
    J L Sartin
    Department Anatomy, Physiology and Pharmacology, Auburn University, AL 36849, USA
    Domest Anim Endocrinol 29:446-55. 2005
  6. ncbi request reprint Intracerebroventricular melanin-concentrating hormone stimulates food intake in sheep
    B K Whitlock
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Domest Anim Endocrinol 28:224-32. 2005
  7. doi request reprint Interaction of kisspeptin and the somatotropic axis
    B K Whitlock
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tenn, USA
    Neuroendocrinology 92:178-88. 2010
  8. doi request reprint Comparative aspects of the endotoxin- and cytokine-induced endocrine cascade influencing neuroendocrine control of growth and reproduction in farm animals
    B K Whitlock
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Reprod Domest Anim 43:317-23. 2008
  9. ncbi request reprint Regulation of the growth hormone and luteinizing hormone response to endotoxin in sheep
    J A Daniel
    Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Domest Anim Endocrinol 23:361-70. 2002
  10. ncbi request reprint Long-term feed intake regulation in sheep is mediated by opioid receptors
    F Y Obese
    Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    J Anim Sci 85:111-7. 2007

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849 5520, USA
    J Anim Sci 81:1546-51. 2003
    ..Although the initiation of responses mediated by TNF, cortisol, and PRC do not seem to be differentially affected by EP, components of the nitric oxide- and TXB-axis responses to LPS are decreased in calves pretreated with EP...
  2. doi request reprint Central role of the melanocortin-4 receptors in appetite regulation after endotoxin
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    J Anim Sci 86:2557-67. 2008
    ..These studies support the notion of the MC4R as a critical component of the mechanism for appetite suppression due to endotoxin...
  3. ncbi request reprint Reduced growth of calves and its reversal by use of anabolic agents
    J L Sartin
    Departments of Anatomy, Physiology and Pharmacology, Alabama Agricultural Experiment Station, Auburn University, Auburn, AL 36849 5518, USA
    Domest Anim Endocrinol 19:85-92. 2000
    ..While the mechanism of action of GH in endotoxemia has been examined, the effects of EP are via an unknown mechanism, possibly by inhibition of IL-I action or inhibition of nitric oxide overproduction...
  4. ncbi request reprint Effect of intracerebroventricular orexin-B on food intake in sheep
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849 5518, USA
    J Anim Sci 79:1573-7. 2001
    ..002). Cortisol was increased by orexin at the 0- to 2-h (P < 0.008) and in the 2- to 4-h (P < 0.009) intervals after orexin injection. These data indicate that central administration of orexin stimulates feed intake in sheep...
  5. ncbi request reprint Melanocortin-4 receptor in sheep: a potential site for therapeutic intervention in disease models
    J L Sartin
    Department Anatomy, Physiology and Pharmacology, Auburn University, AL 36849, USA
    Domest Anim Endocrinol 29:446-55. 2005
    ..Current studies are examining the role that MC4-R antagonists may have in the prevention or correction of body mass wasting diseases as well as practical applications in animal production...
  6. ncbi request reprint Intracerebroventricular melanin-concentrating hormone stimulates food intake in sheep
    B K Whitlock
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Domest Anim Endocrinol 28:224-32. 2005
    ..Finally, using real time PCR, MCH mRNA was unchanged by fasting. In this study we found bolus ICV MCH to be a potent stimulus to food intake in sheep, but MCH was not regulated by fasting...
  7. doi request reprint Interaction of kisspeptin and the somatotropic axis
    B K Whitlock
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tenn, USA
    Neuroendocrinology 92:178-88. 2010
    ..In addition to activating the gonadotropic axis, kisspeptin can activate the somatotropic axis in ruminants. Present data support the concept of a central site of action for this effect...
  8. doi request reprint Comparative aspects of the endotoxin- and cytokine-induced endocrine cascade influencing neuroendocrine control of growth and reproduction in farm animals
    B K Whitlock
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Reprod Domest Anim 43:317-23. 2008
    ..This pathway-based analysis is critical to the developing novel strategies to reverse the detrimental effect of disease on animal production...
  9. ncbi request reprint Regulation of the growth hormone and luteinizing hormone response to endotoxin in sheep
    J A Daniel
    Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Domest Anim Endocrinol 23:361-70. 2002
    ..However, other studies suggest that endotoxin may also regulate LH secretion at the pituitary. Thus, IL-1 and TNF regulate GH release from the pituitary gland while endotoxin induces a central inhibition of LH release...
  10. ncbi request reprint Long-term feed intake regulation in sheep is mediated by opioid receptors
    F Y Obese
    Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    J Anim Sci 85:111-7. 2007
    ..v. injection, and its effects are mediated via opioid receptors. However, the LPS-induced suppression in feed intake cannot be overcome by the opioid receptor ligand, SD33...
  11. doi request reprint Triennial Growth Symposium: neural regulation of feed intake: modification by hormones, fasting, and disease
    J L Sartin
    Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    J Anim Sci 89:1991-2003. 2011
    ..This review will begin with the central nervous system pathways and then discuss the ways in which hormones and metabolites may alter the process to affect feed intake with emphasis on farm animals...
  12. ncbi request reprint Effect of body fat mass and nutritional status on 24-hour leptin profiles in ewes
    J A Daniel
    Department of Anatomy, Physiology, and Pharmacology, Auburn University, AL 36849, USA
    J Anim Sci 80:1083-9. 2002
    ..056). These results provide evidence that plasma concentrations of leptin are episodic in nature and are influenced by nutritive state and fat thickness over the ribs, but display no circadian variation...
  13. ncbi request reprint Alterations in the growth hormone/insulin-like growth factor I pathways in feline GM1 gangliosidosis
    N R Cox
    Scott Ritchey Research Center, Auburn University College of Veterinary Medicine, Alabama 36849, USA
    Endocrinology 140:5698-704. 1999
    ....
  14. doi request reprint Acute regulation of IGF-I by alterations in post-exercise macronutrients
    E B Foster
    Department of Kinesiology, Auburn University, Auburn, AL, USA
    Amino Acids 42:1405-16. 2012
    ..These results indicate that post-exercise macronutrient ratio is a determinant of [free IGF-I], [IGFBP-1 and -2] and may play a role in modulating the IGF-I axis in vivo...
  15. ncbi request reprint Selected hormonal and neurotransmitter mechanisms regulating feed intake in sheep
    J L Sartin
    1Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA
    Animal 4:1781-9. 2010
    ..Thus, knowledge of the mechanisms regulating feed intake in the hypothalamus may lead to mechanisms to increase feed intake in normal growing animals and prevent the wasting effects of severe disease in animals...
  16. ncbi request reprint Interaction of cyclic AMP- and calcium-dependent mechanisms in the regulation of growth hormone-releasing hormone-stimulated growth hormone release from ovine pituitary cells
    J L Sartin
    Department of Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, AL 36849 5520, USA
    Domest Anim Endocrinol 13:229-38. 1996
    ..This suggests that Ca2+ activates calmodulin, which in turn enhances adenylyl cyclase and/or PKA activity to release GH from the sheep pituitary...
  17. ncbi request reprint Leptin, tumor necrosis factor-alpha (TNF), and CD14 in ovine adipose tissue and changes in circulating TNF in lean and fat sheep
    J A Daniel
    South Dakota State University, Brookings, SD 57007, USA
    J Anim Sci 81:2590-9. 2003
    ....
  18. ncbi request reprint Effect of progressive cachectic parasitism and growth hormone treatment on hepatic 5'-deiodinase activity in calves
    Stanislaw Kahl
    Growth Biology Laboratory, US Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Building 200, Room 211E, Beltsville, MD 20705, USA
    Domest Anim Endocrinol 22:211-21. 2002
    ..After recovery from the APR, thyroidal secretion returns to normal but basal and bGH-stimulated generation of T(3) in liver remains impaired...
  19. ncbi request reprint Interleukin-1beta and tumor necrosis factor-alpha mediation of endotoxin action on growth hormone
    J A Daniel
    Animal and Range Sciences, South Dakota State University, Brookings, South Dakota, USA
    Am J Physiol Endocrinol Metab 289:E650-7. 2005
    ..These data are consistent with the effects of LPS on GH secretion originating through peripheral cytokine presentation to the pituitary, as well as a potential to act directly on selective populations of pituitary cells via CD14...
  20. doi request reprint Critical control points in the impact of the proinflammatory immune response on growth and metabolism
    T H Elsasser
    United States Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
    J Anim Sci 86:E105-25. 2008
    ..Attenuation of these overt posttranslational protein modifications at their site of production offers a strategy to minimize their detrimental impact while preserving needed cytokine, NO, and O2(.-) functions...
  21. ncbi request reprint Modeling growth factor activity during proinflammatory stress: methodological considerations in assessing cytokine modulation of IGF binding proteins released by cultured bovine kidney epithelial cells
    T H Elsasser
    US Department of Agriculture, Agricultural Research Service, Growth Biology Laboratory, Beltsville, MD 20705, United States
    Domest Anim Endocrinol 33:390-9. 2007
    ....
  22. ncbi request reprint Endotoxin inhibition of luteinizing hormone in sheep
    J A Daniel
    Animal and Range Science Department, South Dakota State University, Brookings, SD 57007, USA
    Domest Anim Endocrinol 25:13-9. 2003
    ....