Research Topics
| DARIYA MALYARENKOSummaryAffiliation: College of William and Mary Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Enhancement of sensitivity and resolution of surface-enhanced laser desorption/ionization time-of-flight mass spectrometric records for serum peptides using time-series analysis techniquesDariya I Malyarenko
Departments of Applied Science, The College of William and Mary, Williamsburg, VA 23187 8795, USA
Clin Chem 51:65-74. 2005..Many of these effects can be reduced by processing the signal using standard time-series background subtraction, calibration, and filtering techniques...
Automated assignment of ionization states in broad-mass matrix-assisted laser desorption/ionization spectra of protein mixturesDariya I Malyarenko
Department of Applied Science, College of William and Mary, Williamsburg, VA 23187 8795, USA
Rapid Commun Mass Spectrom 24:138-46. 2010..The described automated procedure improves the analysis and dimension reduction of MS data for comparative proteomics applications...
A Bayesian network approach to feature selection in mass spectrometry dataKarl W Kuschner
Department of Physics, The College of William and Mary, Williamsburg, VA, USA
BMC Bioinformatics 11:177. 2010....
Deconvolution filters to enhance resolution of dense time-of-flight survey spectra in the time-lag optimization rangeDariya I Malyarenko
Departments of Physics and Applied Science, College of William and Mary, Williamsburg, VA 23187 8795, USA
Rapid Commun Mass Spectrom 20:1661-9. 2006..The net result of the application of these filters is that we can identify new structures in dense MALDI-TOF data, clearly showing small adducts to heavy biomolecules...
Resampling and deconvolution of linear time-of-flight records for enhanced protein profilingDariya I Malyarenko
Departments of Physics and Applied Science, College of William and Mary, Williamsburg, VA 23187 8795, USA
Rapid Commun Mass Spectrom 20:1670-8. 2006..This approach is particularly appropriate for automated data analysis and peak detection in dense TOF spectra...
Optimization of MALDI-TOF MS detection for enhanced sensitivity of affinity-captured proteins spanning a 100 kDa mass rangeChristine L Gatlin-Bunai
Department of Applied Science, The College of William and Mary, Williamsburg, Virginia 23185, USA
J Proteome Res 6:4517-24. 2007..This enhancement in broad mass range detection of protein signals will be of direct benefit in MS expression profiling studies requiring full linear range mass detection...
Precision enhancement of MALDI-TOF MS using high resolution peak detection and label-free alignmentMaureen B Tracy
William and Mary Research Institute, College of William and Mary, Williamsburg, VA, USA
Proteomics 8:1530-8. 2008..We show that the CV for m/z is 0.01% (100 ppm) for 12 out of the 13 peaks that were observed in all datasets between 2995 and 9297 Da...
Research Grants
- Enhancement of MS signal processing toward improved cancer biomarker discoveryDARIYA MALYARENKO; Fiscal Year: 2009....
