M K Boudreaux

Summary

Affiliation: College of Veterinary Medicine
Country: USA

Publications

  1. doi request reprint Inherited platelet disorders
    Mary K Boudreaux
    From the Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849 5519, USA
    J Vet Emerg Crit Care (San Antonio) 22:30-41. 2012
  2. doi request reprint P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 68499, USA
    Vet Clin Pathol 40:202-6. 2011
  3. doi request reprint Unique structure of the M loop region of β1-tubulin may contribute to size variability of platelets in the family Felidae
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA
    Vet Clin Pathol 39:417-23. 2010
  4. ncbi request reprint Calcium diacylglycerol guanine nucleotide exchange factor I (CalDAG-GEFI) gene mutations in a thrombopathic Simmental calf
    M K Boudreaux
    Department of Pathobiology, Auburn University, AL 36849 5519, USA
    Vet Pathol 44:932-5. 2007
  5. ncbi request reprint Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine platelets
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849 5519, USA
    Transl Res 150:81-92. 2007
  6. ncbi request reprint Evaluation of antithrombin-III activity as a coindicator of disseminated intravascular coagulation in cats with induced feline infectious peritonitis virus infection
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University AL 36849 1159
    Am J Vet Res 50:1910-3. 1989
  7. ncbi request reprint Molecular and genetic basis for thrombasthenic thrombopathia in otterhounds
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849-5519, USA
    Am J Vet Res 62:1797-804. 2001
  8. ncbi request reprint Two genetic defects in alphaIIb are associated with type I Glanzmann's thrombasthenia in a Great Pyrenees dog: a 14-base insertion in exon 13 and a splicing defect of intron 13
    D L Lipscomb
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Vet Pathol 37:581-8. 2000
  9. doi request reprint Mutation in beta1-tubulin correlates with macrothrombocytopenia in Cavalier King Charles Spaniels
    B Davis
    Department of Pathobiology, Auburn University, AL 36849 5519, USA
    J Vet Intern Med 22:540-5. 2008
  10. ncbi request reprint Platelet function, antithrombin-III activity, and fibrinogen concentration in heartworm-infected and heartworm-negative dogs treated with thiacetarsamide
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849 5519
    Am J Vet Res 52:1986-91. 1991

Collaborators

Detail Information

Publications16

  1. doi request reprint Inherited platelet disorders
    Mary K Boudreaux
    From the Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849 5519, USA
    J Vet Emerg Crit Care (San Antonio) 22:30-41. 2012
    ..To present the latest information on inherited platelet disorders in domestic animals...
  2. doi request reprint P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 68499, USA
    Vet Clin Pathol 40:202-6. 2011
    ..This disorder is particularly troublesome because spontaneous hemorrhage is absent to mild in affected dogs; however, following routine surgical procedures or trauma, excessive bleeding could occur and have possible fatal consequences...
  3. doi request reprint Unique structure of the M loop region of β1-tubulin may contribute to size variability of platelets in the family Felidae
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA
    Vet Clin Pathol 39:417-23. 2010
    ..Mutations in the gene encoding β1-tubulin have been documented in dogs and people, and the resulting microtubule effects have been associated with production of large platelets...
  4. ncbi request reprint Calcium diacylglycerol guanine nucleotide exchange factor I (CalDAG-GEFI) gene mutations in a thrombopathic Simmental calf
    M K Boudreaux
    Department of Pathobiology, Auburn University, AL 36849 5519, USA
    Vet Pathol 44:932-5. 2007
    ..This change is likely responsible for the thrombopathic phenotype observed in Simmental cattle and underscores the critical nature of this signal transduction protein in platelets...
  5. ncbi request reprint Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine platelets
    Mary K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849 5519, USA
    Transl Res 150:81-92. 2007
    ....
  6. ncbi request reprint Evaluation of antithrombin-III activity as a coindicator of disseminated intravascular coagulation in cats with induced feline infectious peritonitis virus infection
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University AL 36849 1159
    Am J Vet Res 50:1910-3. 1989
    ..On PID 4 and 16 or 21, results of coagulation screening tests indicated that all cats had disseminated intravascular coagulation. Histologically, cats also had severe fibrinonecrotizing thrombovasculitis...
  7. ncbi request reprint Molecular and genetic basis for thrombasthenic thrombopathia in otterhounds
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849-5519, USA
    Am J Vet Res 62:1797-804. 2001
    ..CONCLUSIONS AND CLINICAL RELEVANCE: These studies suggest that thrombasthenic thrombopathia of Otterhounds is homologous phenotypically and has a similar molecular basis to type-I Glanzmann's thrombasthenia in humans...
  8. ncbi request reprint Two genetic defects in alphaIIb are associated with type I Glanzmann's thrombasthenia in a Great Pyrenees dog: a 14-base insertion in exon 13 and a splicing defect of intron 13
    D L Lipscomb
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Vet Pathol 37:581-8. 2000
    ..A defined molecular basis for canine GT will enhance ongoing gene therapy research and increase the understanding of structure-function relationships of this integrin...
  9. doi request reprint Mutation in beta1-tubulin correlates with macrothrombocytopenia in Cavalier King Charles Spaniels
    B Davis
    Department of Pathobiology, Auburn University, AL 36849 5519, USA
    J Vet Intern Med 22:540-5. 2008
    ..Cavalier King Charles Spaniels (CKCS) have a high prevalence of inherited macrothrombocytopenia. The purpose of this study was to determine if a mutation in beta1-tubulin correlated with presumptive inherited macrothrombocytopenia...
  10. ncbi request reprint Platelet function, antithrombin-III activity, and fibrinogen concentration in heartworm-infected and heartworm-negative dogs treated with thiacetarsamide
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849 5519
    Am J Vet Res 52:1986-91. 1991
    ..In this study, thiacetarsamide was procagulatory in heartworm-negative dogs and may be an important contributing factor to the thromboembolism observed with adulticidal therapy...
  11. ncbi request reprint Nucleotide sequence of the canine alphaIIb gene from platelet-derived cDNA
    D L Lipscomb
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Am J Vet Res 62:1486-92. 2001
    ..To determine the nucleotide sequence of the alphaIIb gene from canine platelet-derived cDNA...
  12. ncbi request reprint Characterization of the cDNA Encoding alphaIIb and beta3 in normal horses and two horses with Glanzmann thrombasthenia
    P W Christopherson
    Department of Pathobiology, 166 Greene Hall, College of Veterinary Medicine, Auburn University, AL 36849 5519, USA
    Vet Pathol 43:78-82. 2006
    ..The subunits are encoded by separate genes and both subunits must be expressed for a stable complex to form on the platelet surface; therefore, a defect in either gene can result in GT...
  13. ncbi request reprint Clinical, biochemical, and molecular aspects of Glanzmann's thrombasthenia in humans and dogs
    M K Boudreaux
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849 5519, USA
    Vet Pathol 38:249-60. 2001
    ..The following review focuses on the structure and function of this platelet receptor and reviews the molecular, biochemical, and clinical aspects of Glanzmann's thrombasthenia in humans and dogs...
  14. ncbi request reprint Enhanced platelet reactivity in cats experimentally infected with feline infectious peritonitis virus
    M K Boudreaux
    Auburn University, College of Veterinary Medicine, Department of Pathobiology, AL
    Vet Pathol 27:269-73. 1990
    ..Although the mechanism for the enhanced platelet responses observed on day 4 was unknown, a direct effect on the virus on platelets, mononuclear inflammatory cells, and endothelial cells must be considered...
  15. ncbi request reprint Use of a polymerase chain reaction assay to detect infection with Eperythrozoon wenyoni in cattle
    J M Vandervoort
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Illinois, Urbana 61801, USA
    J Am Vet Med Assoc 219:1432-4. 2001
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that a PCR assay may be an effective method for detecting E wenyoni infection in cattle and that the PCR assay may be a more sensitive test than evaluation of blood smears...
  16. ncbi request reprint DNA sequence of the canine platelet beta3 gene from cDNA: comparison of canine and mouse beta3 to segments that encode alloantigenic sites and functional domains of beta3 in human beings
    D L Lipscomb
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, Alabama 36849, USA
    J Lab Clin Med 134:313-21. 1999
    ..Knowledge of the beta3 gene nucleotide sequence of normal dogs will facilitate the understanding of platelet alphaIIb beta3 structure-function relationships...