Affiliation: Colgate University
Ay A, Holland J, Sperlea A, Devakanmalai G, Knierer S, Sangervasi S, et al
. Spatial gradients of protein-level time delays set the pace of the traveling segmentation clock waves. Development. 2014;141:4158-67 pubmed publisher
Keskin S, Simsek M, Vu H, Yang C, Devoto S, Ay A, et al
. Regulatory Network of the Scoliosis-Associated Genes Establishes Rostrocaudal Patterning of Somites in Zebrafish. iScience. 2019;12:247-259 pubmed publisher
..Our study provides a blueprint of the zebrafish segmentation network, which includes evolutionarily conserved genes that are associated with the birth defect congenital scoliosis in humans. ..
Ay A, Gong D, Kahveci T. Hierarchical decomposition of dynamically evolving regulatory networks. BMC Bioinformatics. 2015;16:161 pubmed publisher
..Furthermore, our method is robust against dynamic changes in hierarchy. Our experiments on human gene regulatory networks suggest that our method may be used to reconstruct hierarchy in gene regulatory networks. ..