Alexei Koulakov

Summary

Affiliation: Cold Spring Harbor Laboratory
Country: USA

Publications

  1. ncbi request reprint Olfactory coding with all-or-nothing glomeruli
    Alexei Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    J Neurophysiol 98:3134-42. 2007
  2. pmc In search of the structure of human olfactory space
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Neuroscience Program Cold Spring Harbor, NY, USA
    Front Syst Neurosci 5:65. 2011
  3. pmc The problem of colliding networks and its relation to cell fusion and cancer
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    Biophys J 103:2011-20. 2012
  4. pmc Sperry versus Hebb: topographic mapping in Isl2/EphA3 mutant mice
    Dmitry Tsigankov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    BMC Neurosci 11:155. 2010
  5. pmc Correlated connectivity and the distribution of firing rates in the neocortex
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    J Neurosci 29:3685-94. 2009
  6. pmc A stochastic model for retinocollicular map development
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY, 11724, USA
    BMC Neurosci 5:30. 2004
  7. ncbi request reprint How to find decision makers in neural networks
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Biol Cybern 93:447-62. 2005
  8. pmc Sparse incomplete representations: a potential role of olfactory granule cells
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Neuron 72:124-36. 2011
  9. ncbi request reprint The molecular basis for the development of neural maps
    Yi Wei
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    Ann N Y Acad Sci 1305:44-60. 2013
  10. pmc Optimal axonal and dendritic branching strategies during the development of neural circuitry
    Dmitry Tsigankov
    Cold Spring Harbor Laboratory, Cold Spring Harbor NY, USA
    Front Neural Circuits 3:18. 2009

Detail Information

Publications13

  1. ncbi request reprint Olfactory coding with all-or-nothing glomeruli
    Alexei Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    J Neurophysiol 98:3134-42. 2007
    ..We conclude that a combinatorial code based on a binary glomerular response is sufficient to account for several important features of the discrimination capacity of the mammalian olfactory system...
  2. pmc In search of the structure of human olfactory space
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Neuroscience Program Cold Spring Harbor, NY, USA
    Front Syst Neurosci 5:65. 2011
    ..We show that one of the dimensions is related to eigenvalues of molecules' connectivity matrix, while the other is correlated with measures of molecules' polarity. We discuss the behavioral significance of these findings...
  3. pmc The problem of colliding networks and its relation to cell fusion and cancer
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    Biophys J 103:2011-20. 2012
    ..Finally, we suggest that the problem of colliding networks has general significance in many processes represented by attractor networks, including biological, social, and political phenomena...
  4. pmc Sperry versus Hebb: topographic mapping in Isl2/EphA3 mutant mice
    Dmitry Tsigankov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    BMC Neurosci 11:155. 2010
    ..In the Isl2/EphA3 mutant mice the expression levels of molecular labels are changed. As a result the topographic projection is rewired so that the neighborhood relationships between retinal cell axons are disrupted...
  5. pmc Correlated connectivity and the distribution of firing rates in the neocortex
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    J Neurosci 29:3685-94. 2009
    ..Our results represent a first step toward reconciling sparse activity and sparse connectivity in cortical networks...
  6. pmc A stochastic model for retinocollicular map development
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY, 11724, USA
    BMC Neurosci 5:30. 2004
    ..In this study we address possible reasons for such a bifurcation of the map...
  7. ncbi request reprint How to find decision makers in neural networks
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Biol Cybern 93:447-62. 2005
    ..The latter definition is shown to be equivalent to the first one in the cases when they can be compared. Our results suggest a new approach to analyzing decision making networks...
  8. pmc Sparse incomplete representations: a potential role of olfactory granule cells
    Alexei A Koulakov
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Neuron 72:124-36. 2011
    ..Our model suggests functional significance for the dendrodendritic synapses mediating interactions between mitral and granule cells...
  9. ncbi request reprint The molecular basis for the development of neural maps
    Yi Wei
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    Ann N Y Acad Sci 1305:44-60. 2013
    ..Overall, we propose that simple mechanisms can account for the formation of apparently complex features of neuronal connections. ..
  10. pmc Optimal axonal and dendritic branching strategies during the development of neural circuitry
    Dmitry Tsigankov
    Cold Spring Harbor Laboratory, Cold Spring Harbor NY, USA
    Front Neural Circuits 3:18. 2009
    ..Thus, our studies suggest that the developing neural system employs a set of sophisticated computational strategies that facilitate the formation of required circuitry in the fastest and most frugal way...
  11. pmc Neural integrator: a sandpile model
    Maxim Nikitchenko
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Neural Comput 20:2379-417. 2008
    ..Finally, we investigate the conditions under which the hysteretic integrator may have no threshold for integration...
  12. ncbi request reprint Maps in the brain: what can we learn from them?
    Dmitri B Chklovskii
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Annu Rev Neurosci 27:369-92. 2004
    ..These solutions can help us in inferring intracortical connectivity and, ultimately, in understanding the function of the visual system...
  13. ncbi request reprint Speed-accuracy tradeoff in olfaction
    Dmitry Rinberg
    Monell Chemical Senses Center, 3500 Market Street, Philadelphia, Pennsylvania 19104, USA
    Neuron 51:351-8. 2006
    ..The presence of SAT in olfaction provides strong evidence for temporal integration in olfaction and puts a constraint on models of olfactory processing...

Research Grants4

  1. Quantitiative model for the development of neural topographic maps
    Alexei Koulakov; Fiscal Year: 2010
    ..All studies will be carried out in close collaboration with experimental groups. Expert advice will be solicited on all stages of the project. ..
  2. Quantitiative model for the development of neural topographic maps
    Alexei Koulakov; Fiscal Year: 2009
    ..All studies will be carried out in close collaboration with experimental groups. Expert advice will be solicited on all stages of the project. ..
  3. CRCNS: Computational Model for Neural Stem Cell Divisions in the Adult Brain
    Alexei Koulakov; Fiscal Year: 2010
    ..Because the lifetime incidence of depression in the US is more than 12% in men and 20% in women, our studies may substantially contribute to public health. ..