Research Topics
| A KepecsSummaryAffiliation: Cold Spring Harbor Laboratory Country: USA Publications
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Detail Information
Publications
Rapid and precise control of sniffing during olfactory discrimination in ratsAdam Kepecs
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
J Neurophysiol 98:205-13. 2007..These results demonstrate the speed and precision of control over respiration and its significance for olfactory behavioral performance...
Choice ball: a response interface for two-choice psychometric discrimination in head-fixed miceJoshua I Sanders
Cold Spring Harbor, NY 11724
J Neurophysiol 108:3416-23. 2012..The choice ball enables head-fixed 2AFC paradigms, facilitating the circuit-level analysis of sensory processing, decision making, and motor control in mice...
A computational framework for the study of confidence in humans and animalsAdam Kepecs
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Philos Trans R Soc Lond B Biol Sci 367:1322-37. 2012..Finally, we discuss the relationship of confidence judgements to the wider behavioural uses of confidence and uncertainty...
Neural correlates, computation and behavioural impact of decision confidenceAdam Kepecs
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
Nature 455:227-31. 2008..We suggest that confidence estimation may be a fundamental and ubiquitous component of decision-making...
Gating information by two-state membrane potential fluctuationsA Kepecs
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
J Neurophysiol 97:3015-23. 2007..The dynamic gating of input by up- and down-states may be an elementary operation for the selective routing of signals in neural circuits, which may explain the ubiquity of two-state fluctuations across brain regions...
Basic mechanisms for graded persistent activity: discrete attractors, continuous attractors, and dynamic representationsCarlos D Brody
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Curr Opin Neurobiol 13:204-11. 2003....
The sniff as a unit of olfactory processingAdam Kepecs
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Chem Senses 31:167-79. 2006..Further electrophysiological recordings in behaving animals will be necessary to assess these proposals...
Seeing at a glance, smelling in a whiff: rapid forms of perceptual decision makingNaoshige Uchida
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
Nat Rev Neurosci 7:485-91. 2006..We suggest that the brain limits some types of perceptual processing to short, discrete chunks (for example, eye fixations and sniffs) in order to facilitate the construction of global sensory images...
Spike-timing-dependent plasticity: common themes and divergent vistasAdam Kepecs
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Biol Cybern 87:446-58. 2002..In light of these computational issues raised, we review current experimental findings and suggest further experiments to resolve some controversies...
Information encoding and computation with spikes and burstsAdam Kepecs
Volen Center for Complex Systems, Brandeis University, 415 South Street, Waltham, MA 02454, USA
Network 14:103-18. 2003..These findings lead us to propose that the biophysical mechanisms of spike generation enables individual neurons to encode different stimulus features into distinct spike patterns...
Model for a robust neural integratorAlexei A Koulakov
Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
Nat Neurosci 5:775-82. 2002..Neither circuit requires fine tuning to perform robust integration, and the latter actually exploits the variability of neuronal conductances...
Bursting neurons signal input slopeAdam Kepecs
Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454-9110, USA
J Neurosci 22:9053-62. 2002..This possibility could be further examined experimentally by looking for correlations between burst duration and stimulus variables...
