You are here: Scientific Experts > USA > Cold Spring Harbor Laboratory > Joshua Tor > Leemor Joshua Tor
protein interaction domains and motifs
molecular docking simulation
eukaryotic initiation factors
Genomes and Genes
Archaeoglobus fulgidus DSM 4304
Leemor Joshua Tor
Cold Spring Harbor Laboratory
Joshua Tor L, Hannon G. Ancestral roles of small RNAs: an Ago-centric perspective. Cold Spring Harb Perspect Biol. 2011;3:a003772
..Here, we discuss the diversity of Argonaute proteins from a structural and functional perspective. ..
Kuhn C, Wilusz J, Zheng Y, Beal P, Joshua Tor L. On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell. 2015;160:644-658
..Intriguingly, with the CCA-adding enzyme acting as a molecular vise, the RNAs proofread themselves through differential responses to its interrogation between stable and unstable substrates. ..
Elkayam E, Faehnle C, Morales M, Sun J, Li H, Joshua Tor L. Multivalent Recruitment of Human Argonaute by GW182. Mol Cell. 2017;67:646-658.e3
..Finally, we show that hGW182 can recruit up to three copies of hAgo via its three GW motifs. This may explain the observed cooperativity in miRNA-mediated gene silencing. ..
Experts and Doctors on phylogeny in New York, United States
Experts and Doctors on rna interference in New York, United States
Experts and Doctors on conserved sequence in New York, United States
Labome.Org © 2018 All Rights Researved
Princeton, New Jersey 08540, USA
last updated: January 02, 2019