Leemor Joshua Tor

Summary

Affiliation: Cold Spring Harbor Laboratory
Country: USA

Publications

  1. Joshua Tor L, Hannon G. Ancestral roles of small RNAs: an Ago-centric perspective. Cold Spring Harb Perspect Biol. 2011;3:a003772 pubmed publisher
    ..Here, we discuss the diversity of Argonaute proteins from a structural and functional perspective. ..
  2. Kuhn C, Wilusz J, Zheng Y, Beal P, Joshua Tor L. On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell. 2015;160:644-658 pubmed publisher
    ..Intriguingly, with the CCA-adding enzyme acting as a molecular vise, the RNAs proofread themselves through differential responses to its interrogation between stable and unstable substrates. ..
  3. Elkayam E, Faehnle C, Morales M, Sun J, Li H, Joshua Tor L. Multivalent Recruitment of Human Argonaute by GW182. Mol Cell. 2017;67:646-658.e3 pubmed publisher
    ..Finally, we show that hGW182 can recruit up to three copies of hAgo via its three GW motifs. This may explain the observed cooperativity in miRNA-mediated gene silencing. ..