Masaaki Hamaguchi

Summary

Affiliation: Cold Spring Harbor Laboratory
Country: USA

Publications

  1. pmc DBC2, a candidate for a tumor suppressor gene involved in breast cancer
    Masaaki Hamaguchi
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Proc Natl Acad Sci U S A 99:13647-52. 2002
  2. ncbi request reprint DBC2 significantly influences cell-cycle, apoptosis, cytoskeleton and membrane-trafficking pathways
    Veeraiah Siripurapu
    Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724, USA
    J Mol Biol 346:83-9. 2005
  3. pmc DBC2 is essential for transporting vesicular stomatitis virus glycoprotein
    Faith K Chang
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Bronx, NY 10458, USA
    J Mol Biol 364:302-8. 2006
  4. pmc Cyclin D1 down-regulation is essential for DBC2's tumor suppressor function
    Takashi Yoshihara
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Larkin Hall, Bronx, NY 10458, USA
    Biochem Biophys Res Commun 358:1076-9. 2007
  5. pmc DBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradation
    Denise Collado
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Larkin Hall, Bronx, NY 10458, USA
    Biochem Biophys Res Commun 360:600-3. 2007

Collaborators

  • Mary Claire King
  • Piri Welcsh
  • Takashi Yoshihara
  • Denise Collado
  • Faith K Chang
  • Veeraiah Siripurapu
  • Noriko Kobayashi-Simorowski
  • Jennifer L Meth
  • Noriko Sato
  • Noriko Kobayashi
  • Jennifer Meth

Detail Information

Publications5

  1. pmc DBC2, a candidate for a tumor suppressor gene involved in breast cancer
    Masaaki Hamaguchi
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Proc Natl Acad Sci U S A 99:13647-52. 2002
    ..By contrast, expression of a somatic mutant discovered in a breast cancer specimen does not suppress the growth of breast cancer cells...
  2. ncbi request reprint DBC2 significantly influences cell-cycle, apoptosis, cytoskeleton and membrane-trafficking pathways
    Veeraiah Siripurapu
    Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724, USA
    J Mol Biol 346:83-9. 2005
    ..The other network is related to cytoskeleton and membrane trafficking. Our findings suggest that the biological roles of DBC2 are related directly and/or indirectly to these cellular machineries...
  3. pmc DBC2 is essential for transporting vesicular stomatitis virus glycoprotein
    Faith K Chang
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Bronx, NY 10458, USA
    J Mol Biol 364:302-8. 2006
    ..We demonstrate that DBC2 mobility depends also on an intact microtubule network. We conclude that DBC2 plays an essential role in microtubule-mediated VSVG transport from the endoplasmic reticulum to the Golgi apparatus...
  4. pmc Cyclin D1 down-regulation is essential for DBC2's tumor suppressor function
    Takashi Yoshihara
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Larkin Hall, Bronx, NY 10458, USA
    Biochem Biophys Res Commun 358:1076-9. 2007
    ..Our results indicate that the down-regulation of CCND1 is an essential step for DBC2's growth suppression of cancer cells. We believe that this discovery contributes to a better understanding of DBC2's tumor suppressor function...
  5. pmc DBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradation
    Denise Collado
    Department of Biological Sciences, Fordham University, 441 E Fordham Road, Larkin Hall, Bronx, NY 10458, USA
    Biochem Biophys Res Commun 360:600-3. 2007
    ..These findings indicate that the resistant T-47D cells survive DBC2 induction by rapid destruction of DBC2 through 26S proteasome-mediated protein degradation...