Nansheng Chen

Summary

Affiliation: Cold Spring Harbor Laboratory
Country: USA

Publications

  1. pmc WormBase as an integrated platform for the C. elegans ORFeome
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Res 14:2155-61. 2004
  2. pmc WormBase: a comprehensive data resource for Caenorhabditis biology and genomics
    Nansheng Chen
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nucleic Acids Res 33:D383-9. 2005
  3. pmc Identification of a nematode chemosensory gene family
    Nansheng Chen
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Proc Natl Acad Sci U S A 102:146-51. 2005
  4. pmc WormBase: a multi-species resource for nematode biology and genomics
    Todd W Harris
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nucleic Acids Res 32:D411-7. 2004
  5. pmc Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Res 16:606-17. 2006
  6. pmc The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics
    Lincoln D Stein
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    PLoS Biol 1:E45. 2003
  7. pmc Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Biol 7:R126. 2006
  8. doi request reprint Using RepeatMasker to identify repetitive elements in genomic sequences
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    Curr Protoc Bioinformatics . 2004
  9. ncbi request reprint Transcriptional regulation of AQP-8, a Caenorhabditis elegans aquaporin exclusively expressed in the excretory system, by the POU homeobox transcription factor CEH-6
    Allan K Mah
    Department Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
    J Biol Chem 282:28074-86. 2007
  10. pmc Comparative genomics and adaptive selection of the ATP-binding-cassette gene family in caenorhabditis species
    Zhongying Zhao
    British Columbia Cancer Research Center, Vancouver, British Columbia V5Z 1L6, Canada
    Genetics 175:1407-18. 2007

Detail Information

Publications17

  1. pmc WormBase as an integrated platform for the C. elegans ORFeome
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Res 14:2155-61. 2004
    ....
  2. pmc WormBase: a comprehensive data resource for Caenorhabditis biology and genomics
    Nansheng Chen
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nucleic Acids Res 33:D383-9. 2005
    ..Internally, we have restructured the database models to rationalize the representation of genes and to prepare the system to accept the genome sequences of three additional Caenorhabditis species over the coming year...
  3. pmc Identification of a nematode chemosensory gene family
    Nansheng Chen
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Proc Natl Acad Sci U S A 102:146-51. 2005
    ..The expansion of both the srab and sra gene families in C. elegans relative to C. briggsae is due to multiple rounds of tandem duplication and translocation of individual genes...
  4. pmc WormBase: a multi-species resource for nematode biology and genomics
    Todd W Harris
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nucleic Acids Res 32:D411-7. 2004
    ..These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system...
  5. pmc Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Res 16:606-17. 2006
    ....
  6. pmc The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics
    Lincoln D Stein
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    PLoS Biol 1:E45. 2003
    ..elegans genome. Based on similarity to C. briggsae, we found strong evidence for 1,300 new C. elegans genes. In addition, comparisons of the two genomes will help to understand the evolutionary forces that mold nematode genomes...
  7. pmc Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    Genome Biol 7:R126. 2006
    ..Taking this approach, we have identified numerous novel ciliary genes in C. elegans, some of which may be orthologs of unidentified human ciliopathy genes...
  8. doi request reprint Using RepeatMasker to identify repetitive elements in genomic sequences
    Nansheng Chen
    Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
    Curr Protoc Bioinformatics . 2004
    ..The protocols in this chapter detail how to use RepeatMasker both remotely and locally to extract repetitive elements data and mask these repetitive elements in nucleotide sequences...
  9. ncbi request reprint Transcriptional regulation of AQP-8, a Caenorhabditis elegans aquaporin exclusively expressed in the excretory system, by the POU homeobox transcription factor CEH-6
    Allan K Mah
    Department Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
    J Biol Chem 282:28074-86. 2007
    ..These parallels in transcriptional control between Brn1 and CEH-6 suggest that C. elegans may well be an appropriate model for determining gene-regulatory networks in the developing vertebrate kidney...
  10. pmc Comparative genomics and adaptive selection of the ATP-binding-cassette gene family in caenorhabditis species
    Zhongying Zhao
    British Columbia Cancer Research Center, Vancouver, British Columbia V5Z 1L6, Canada
    Genetics 175:1407-18. 2007
    ..Sites undergoing positive selection within subfamily D, which are implicated in very-long-chain fatty acid transport, were identified. The evolution of these sites might be driven by the changes in food source with time...
  11. pmc Gene structure evolution of the Na+-Ca2+ exchanger (NCX) family
    Caly On
    Cardiac Membrane Research Laboratory Kinesiology, Simon Fraser University, Burnaby, BC, Canada
    BMC Evol Biol 8:127. 2008
    ....
  12. pmc WormBase: new content and better access
    Tamberlyn Bieri
    Genome Sequencing Center, Washington University School of Medicine, St Louis, MO 63108, USA
    Nucleic Acids Res 35:D506-10. 2007
    ..Access to and searching WormBase has become more dependable and flexible via multiple mirror sites and indexing through Google...
  13. pmc The genome of the sea urchin Strongylocentrotus purpuratus
    Erica Sodergren
    Science 314:941-52. 2006
    ..This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes...
  14. pmc Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution
    Julia Tischler
    The Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
    Genome Biol 7:R69. 2006
    ..Developing tools for the systematic mapping of genetic interactions is thus a key step in exploring the relationship between genotype and phenotype...
  15. pmc WormBase: better software, richer content
    Erich M Schwarz
    Division of Biology, 156 29 California Institute of Technology, Pasadena, CA, 91125, USA
    Nucleic Acids Res 34:D475-8. 2006
    ....
  16. ncbi request reprint Distinct regulatory elements mediate similar expression patterns in the excretory cell of Caenorhabditis elegans
    Zhongying Zhao
    Department of Genome Science, University of Washington, Seattle, Washington 98195 7730, USA
    J Biol Chem 280:38787-94. 2005
    ..The results indicate that distinct regulatory elements are able to mediate the similar expression patterns...
  17. pmc Identification and characterization of novel human tissue-specific RFX transcription factors
    Syed Aftab
    Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada
    BMC Evol Biol 8:226. 2008
    ....