Eric P Cohen

Summary

Country: USA

Publications

  1. pmc Mitigation of late renal and pulmonary injury after hematopoietic stem cell transplantation
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Int J Radiat Oncol Biol Phys 83:292-6. 2012
  2. pmc Chronic kidney disease after hematopoietic stem cell transplantation
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Semin Nephrol 30:627-34. 2010
  3. pmc Mitigation of radiation injuries via suppression of the renin-angiotensin system: emphasis on radiation nephropathy
    E P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Curr Drug Targets 11:1423-9. 2010
  4. doi request reprint C-reactive protein and dialysis access
    Eric P Cohen
    Nephrology Division, Medical College of Wisconsin, Milwaukee, Wisconsin 53295, USA
    Kidney Int 76:1025-6. 2009
  5. pmc Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat
    Eric P Cohen
    Medical College of Wisconsin, Milwaukee, USA
    Transl Res 157:38-47. 2011
  6. doi request reprint Successful treatment of BK viremia using reduction in immunosuppression without antiviral therapy
    Ehab R Saad
    Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transplantation 85:850-4. 2008
  7. pmc Role of the angiotensin II type-2 receptor in radiation nephropathy
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transl Res 150:106-15. 2007
  8. pmc Chronic oxidative stress as a mechanism for radiation nephropathy
    Marek Lenarczyk
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 171:164-72. 2009
  9. pmc Radiation nephropathy is not mitigated by antagonists of oxidative stress
    Eric P Cohen
    Departments of Medicine and, Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA
    Radiat Res 172:260-4. 2009
  10. pmc Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Int J Radiat Oncol Biol Phys 70:1546-51. 2008

Collaborators

Detail Information

Publications35

  1. pmc Mitigation of late renal and pulmonary injury after hematopoietic stem cell transplantation
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Int J Radiat Oncol Biol Phys 83:292-6. 2012
    ....
  2. pmc Chronic kidney disease after hematopoietic stem cell transplantation
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Semin Nephrol 30:627-34. 2010
    ..Investigation of the causes of chronic kidney disease is needed, as are ways to prevent, mitigate, and treat it...
  3. pmc Mitigation of radiation injuries via suppression of the renin-angiotensin system: emphasis on radiation nephropathy
    E P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Curr Drug Targets 11:1423-9. 2010
    ..These drugs are likely to act in a similar way to mitigate radiation nephropathy...
  4. doi request reprint C-reactive protein and dialysis access
    Eric P Cohen
    Nephrology Division, Medical College of Wisconsin, Milwaukee, Wisconsin 53295, USA
    Kidney Int 76:1025-6. 2009
    ..Inflammation associated with dialysis catheter use could have an independent adverse effect on patient outcomes. Awareness and further study of the role of inflammation are needed...
  5. pmc Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat
    Eric P Cohen
    Medical College of Wisconsin, Milwaukee, USA
    Transl Res 157:38-47. 2011
    ..This activation was attributable at least partially to enhanced pituitary ACTH production...
  6. doi request reprint Successful treatment of BK viremia using reduction in immunosuppression without antiviral therapy
    Ehab R Saad
    Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transplantation 85:850-4. 2008
    ..Treatment of BK virus (BKV) infection in renal transplant recipients remains controversial. This retrospective analysis evaluated efficacy and safety of reducing immunosuppression without antiviral therapy...
  7. pmc Role of the angiotensin II type-2 receptor in radiation nephropathy
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transl Res 150:106-15. 2007
    ..The effect of AT(2) blockade in radiation nephropathy cannot be explained by binding to the AT(1) receptor, and the efficacy of the AT(1) blockade in the same model cannot be explained by unopposed overstimulation of the AT(2) receptor...
  8. pmc Chronic oxidative stress as a mechanism for radiation nephropathy
    Marek Lenarczyk
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 171:164-72. 2009
    ..If chronic oxidative stress is part of the pathogenesis of radiation nephropathy, it does not leave widespread or easily detectable evidence behind...
  9. pmc Radiation nephropathy is not mitigated by antagonists of oxidative stress
    Eric P Cohen
    Departments of Medicine and, Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA
    Radiat Res 172:260-4. 2009
    ..Thus three different types of antioxidants, when used at doses consistent with an antioxidant effect, had no mitigation efficacy against radiation nephropathy...
  10. pmc Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Int J Radiat Oncol Biol Phys 70:1546-51. 2008
    ..To test whether the angiotensin-converting enzyme inhibitor captopril was effective in mitigating chronic renal failure after hematopoietic stem cell transplantation (HSCT)...
  11. doi request reprint Recovery of BK virus large T-antigen-specific cellular immune response correlates with resolution of bk virus nephritis
    Simon E Prosser
    1 Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transplantation 85:185-92. 2008
    ..BKV infection progresses to BKV nephritis (BKVN) in approximately 8% of transplants and in half of these cases the graft is lost...
  12. ncbi request reprint The renin-angiotensin system in experimental radiation nephropathy
    Eric P Cohen
    Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    J Lab Clin Med 139:251-7. 2002
    ..We hypothesize that even the normal activity of the RAS contributes to injury after kidney irradiation, possibly by supporting the proliferation of cells that carry potentially lethal radiation injuries...
  13. ncbi request reprint BK virus-specific antibodies and BKV DNA in renal transplant recipients with BKV nephritis
    Sundaram Hariharan
    The Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Transplant 5:2719-24. 2005
    ..Recovery from BKVN and elimination of BKV is associated with the development of BKV-specific IgG antibodies and this provides insight into the role of humoral immunity to BKV in the pathogenesis of BKVN...
  14. ncbi request reprint Impact of angiotensin II type 2 receptor blockade on experimental radiation nephropathy
    John E Moulder
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 161:312-7. 2004
    ..We speculate that the beneficial effect of the angiotensin II type 2 receptor blocker is due to a reduction in radiation-induced renal cell proliferation or fibrosis...
  15. pmc Captopril and losartan for mitigation of renal injury caused by single-dose total-body irradiation
    John E Moulder
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 175:29-36. 2011
    ..This lays the necessary groundwork for pivotal rodent studies under the FDA Animal Efficacy Rule and provides an outline of how the FDA-required large-animal studies could be designed...
  16. ncbi request reprint BK virus nephritis: risk factors, timing, and outcome in renal transplant recipients
    Brahm Vasudev
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Kidney Int 68:1834-9. 2005
    ..We have thus quantified the timing, risk factors, evolution of renal function, and transplant graft outcome in renal transplant recipients with BKVN from our center...
  17. ncbi request reprint Radiation nephropathy
    Eric P Cohen
    Medical College of Wisconsin, Milwaukee, WI, USA
    Semin Nephrol 23:486-99. 2003
    ..Recent findings suggest a similar benefit in clinical radiation nephropathy...
  18. ncbi request reprint Angiotensin II blockade reduces radiation-induced proliferation in experimental radiation nephropathy
    John E Moulder
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 157:393-401. 2002
    ....
  19. pmc The urine proteome for radiation biodosimetry: effect of total body vs. local kidney irradiation
    Mukut Sharma
    Nephrology Division, Department of Medicine, Research Building Room F2 100, Stop 151, KCVA Medical Center, 4801 Lindwood Blvd, Kansas City, MO 64128, USA
    Health Phys 98:186-95. 2010
    ..These novel findings demonstrate intriguing differences between TBI and LKI, and suggest that urine proteome may be useful in determining organ-specific changes caused by partial body irradiation...
  20. pmc Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and renin-aldosterone activity in the rat
    Hershel Raff
    Endocrine Research Laboratory, Aurora St Luke s Medical Center, Milwaukee, Wisconsin 53215, USA
    Endocrinology 152:1218-21. 2011
    ..We conclude that nearby construction can cause a stress response without long-term effects on hypothalamic-pituitary-adrenal axis gene expression and body weight...
  21. pmc Dietary selenium for the mitigation of radiation injury: effects of selenium dose escalation and timing of supplementation
    Fritz Sieber
    Department of Pediatrics and Children s Research Institute, Milwaukee, Wisconsin 53226, USA
    Radiat Res 176:366-74. 2011
    ..The high dose requirements, the pronounced threshold effect, and the superior performance of selenite suggest that the mitigation of radiation nephropathy involves mechanisms that go beyond the induction of selenoproteins...
  22. pmc High-dose selenium for the mitigation of radiation injury: a pilot study in a rat model
    Fritz Sieber
    Department of Pediatrics and Children s Research Institute, Wisconsin, USA
    Radiat Res 171:368-73. 2009
    ..Our results suggest that dietary supplementation with high-dose selenium may provide a safe, effective and practical way to mitigate radiation injury to kidneys...
  23. ncbi request reprint Future strategies for mitigation and treatment of chronic radiation-induced normal tissue injury
    John E Moulder
    Radiation Oncology and Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Semin Radiat Oncol 17:141-8. 2007
    ....
  24. ncbi request reprint Arachidonic acid metabolites mediate the radiation-induced increase in glomerular albumin permeability
    Mukut Sharma
    Division of Nephrology and the Kidney Disease Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Exp Biol Med (Maywood) 231:99-106. 2006
    ..Understanding of the early epigenetic effects of irradiation may lead to new intervention strategies against radiation-induced injury of normal tissues...
  25. ncbi request reprint Successful treatment of radiation nephropathy with angiotensin II blockade
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Int J Radiat Oncol Biol Phys 55:190-3. 2003
    ..The aim of this report is to document the successful treatment of radiation nephropathy...
  26. ncbi request reprint Benefit of child-to-parent kidney donation
    Eric P Cohen
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Transplant 3:865-72. 2003
    ..We conclude that CTP kidney donation should not be discouraged, and represents a useful source of transplantable kidneys...
  27. ncbi request reprint Evolution of endpoints for renal transplant outcome
    Sundaram Hariharan
    Division of Nephrology, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI 53226, USA
    Am J Transplant 3:933-41. 2003
    ..A practical approach for assessing newer therapies in future studies is to use composite endpoints, which combine conventional endpoints (graft loss, death, acute rejection) with newer endpoints (renal function, histological indices)...
  28. doi request reprint Safety and blood sample volume and quality of a refined retro-orbital bleeding technique in rats using a lateral approach
    Ashish Sharma
    Departments of Radiation Oncology, Surgery and Medicine, Medical College of Wisconsin, Milwaukee, WI
    Lab Anim (NY) 43:63-6. 2014
    ..The authors conclude that, when done using a lateral approach and by an experienced technician, ROB is humane and safe and provides blood samples of adequate volume and quality for analysis. ..
  29. ncbi request reprint Stenosis of the glomerulotubular neck
    Eric P Cohen
    Nephrology Division, Medical College of Wisconsin, Froedtert Hospital, 9200 W Wisconsin Avenue, Milwaukee, WI 53226, USA
    Nephron 92:259-62. 2002
  30. doi request reprint Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy
    Jordan Kharofa
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA
    Int J Radiat Oncol Biol Phys 84:238-43. 2012
    ..The aim of this study was to evaluate whether ACE inhibitors decrease the risk of radiation pneumonitis in lung cancer patients receiving thoracic irradiation...
  31. ncbi request reprint Humanized anti-CD20 monoclonal antibody (Rituximab) treatment for post-transplant lymphoproliferative disorder
    Vasundhara Ganne
    Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Clin Transplant 17:417-22. 2003
    ..The treatment of PTLD includes reduction/withdrawal of immunosuppression and chemotherapy. This study reports our center experience with humanized monoclonal antibody against CD-20 (Rituximab) for the treatment of PTLD...
  32. pmc Percussion hemoglobinuria - a novel term for hand trauma-induced mechanical hemolysis: a case report
    Monica Vasudev
    Division of Nephrology, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee WI 53226, USA
    J Med Case Reports 5:508. 2011
    ..abstract:..
  33. ncbi request reprint Retinoic acid exacerbates experimental radiation nephropathy
    John E Moulder
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Radiat Res 157:199-203. 2002
    ....
  34. ncbi request reprint Subdural hematomas in chronic dialysis patients: significant and increasing
    Puneet Sood
    Department of Medicine, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI 53226, USA
    Clin J Am Soc Nephrol 2:956-9. 2007
    ..Subdural hematoma is a known complication of long-term hemodialysis...
  35. ncbi request reprint Rapid kidney allograft failure in patients with polyoma virus nephritis with prior treatment with antilymphocyte agents
    Syed Hussain
    Division of Nephrology, Medical College of Wisconsin, Milwaukee 53226, USA
    Clin Transplant 16:43-7. 2002
    ..005. The use of ALA was associated with a rapid fall in GFR and graft failure in patients with PVi nephritis. Careful diagnosis of PVi is warranted in renal allograft recipients prior to initiating ALA therapy...