Ke Yang

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. pmc Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels
    Ke Yang
    Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH, USA
    BMC Cell Biol 7:33. 2006
  2. pmc Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression
    Masahiro Hitomi
    Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Mol Cell Biol 28:5478-93. 2008
  3. ncbi request reprint p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point
    Masahiro Hitomi
    The Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cell Cycle 5:2281-9. 2006
  4. ncbi request reprint Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis
    Yang Guo
    Department of Molecular Genetics, The Lerner Research Institute, NC2 151, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Oncogene 24:2599-612. 2005

Collaborators

  • Masahiro Hitomi
  • Yang Guo
  • Jyoti Harwalkar
  • David R Mason
  • Jeffrey M Nye
  • Dennis W Stacey
  • Michelle D Garrett

Detail Information

Publications5

  1. pmc Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels
    Ke Yang
    Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH, USA
    BMC Cell Biol 7:33. 2006
    ....
  2. pmc Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression
    Masahiro Hitomi
    Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Mol Cell Biol 28:5478-93. 2008
    ..These results indicate that checkpoint kinases play a critical role in regulating cell cycle progression in normal and stressed cells by directing the phosphorylation of cyclin D1...
  3. ncbi request reprint p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point
    Masahiro Hitomi
    The Department of Molecular Genetics, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cell Cycle 5:2281-9. 2006
    ..We conclude that the p27 expression level at mid-G(1) phase determines when a cell passes through the restriction point, and does so by regulating subsequent CDK2 activation...
  4. ncbi request reprint Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis
    Yang Guo
    Department of Molecular Genetics, The Lerner Research Institute, NC2 151, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Oncogene 24:2599-612. 2005
    ..In such cells, however, the levels of cyclin D1 would presumably be too high to be suppressed during S phase, resulting in the inhibition of DNA synthesis...