Steven E Wilson

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Long-term outcomes after photorefractive keratectomy
    Steven E Wilson
    Ophthalmology 113:1693-4. 2006
  2. ncbi request reprint Synergistic effect of ethanol and mitomycin C on corneal stroma
    Marcelo V Netto
    Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil
    J Refract Surg 24:626-32. 2008
  3. doi request reprint Flaporhexis: rapid and effective technique to limit epithelial ingrowth after LASIK enhancement
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 38:2-4. 2012
  4. pmc Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency
    Steven E Wilson
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Exp Eye Res 99:78-88. 2012
  5. ncbi request reprint RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Ohio 44195, USA
    Invest Ophthalmol Vis Sci 45:2201-11. 2004
  6. ncbi request reprint Long-term resolution of chronic dry eye symptoms and signs after topical cyclosporine treatment
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmology 114:76-9. 2007
  7. pmc Apoptosis in the initiation, modulation and termination of the corneal wound healing response
    Steven E Wilson
    The Cole Eye Institute, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Exp Eye Res 85:305-11. 2007
  8. ncbi request reprint Clinical practice. Use of lasers for vision correction of nearsightedness and farsightedness
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    N Engl J Med 351:470-5. 2004
  9. pmc Femtosecond laser and microkeratome corneal flaps: comparison of stromal wound healing and inflammation
    Marcelo V Netto
    The Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 23:667-76. 2007
  10. pmc Effect of femtosecond laser energy level on corneal stromal cell death and inflammation
    Fabricio Witzel de Medeiros
    Cleveland Clinic, Cole Eye Institute, Ohio 44195, USA
    J Refract Surg 25:869-74. 2009

Research Grants

Collaborators

Detail Information

Publications75

  1. ncbi request reprint Long-term outcomes after photorefractive keratectomy
    Steven E Wilson
    Ophthalmology 113:1693-4. 2006
  2. ncbi request reprint Synergistic effect of ethanol and mitomycin C on corneal stroma
    Marcelo V Netto
    Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil
    J Refract Surg 24:626-32. 2008
    ..To investigate the combined effects of ethanol and mitomycin C (MMC) application on the corneal stroma of rabbits that underwent photorefractive keratectomy (PRK)...
  3. doi request reprint Flaporhexis: rapid and effective technique to limit epithelial ingrowth after LASIK enhancement
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 38:2-4. 2012
    ..This method consistently produces a smooth epithelial dissection and decreases the possibility that epithelium is retained beneath the flap...
  4. pmc Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency
    Steven E Wilson
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Exp Eye Res 99:78-88. 2012
    ..Investigations of myofibroblast biology are likely to lead to safer pharmacological modulators of corneal wound healing and transparency...
  5. ncbi request reprint RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Ohio 44195, USA
    Invest Ophthalmol Vis Sci 45:2201-11. 2004
    ..To examine the influx of monocytes into the cornea after epithelial scrape injury and the expression of chemokines that potentially regulate monocyte phenotype in cultured corneal fibroblasts and keratocytes in situ...
  6. ncbi request reprint Long-term resolution of chronic dry eye symptoms and signs after topical cyclosporine treatment
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmology 114:76-9. 2007
    ..To report the resolution of symptoms and signs of chronic dry eye for at least 1 year after completion of a minimum 6-month course of topical 0.05% cyclosporine in a subgroup of patients from 2 practices...
  7. pmc Apoptosis in the initiation, modulation and termination of the corneal wound healing response
    Steven E Wilson
    The Cole Eye Institute, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Exp Eye Res 85:305-11. 2007
    ....
  8. ncbi request reprint Clinical practice. Use of lasers for vision correction of nearsightedness and farsightedness
    Steven E Wilson
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    N Engl J Med 351:470-5. 2004
  9. pmc Femtosecond laser and microkeratome corneal flaps: comparison of stromal wound healing and inflammation
    Marcelo V Netto
    The Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 23:667-76. 2007
    ..To examine early postoperative wound healing in rabbit corneas that had LASIK flaps formed with three different models (15 KHz, 30 KhZ, and 60 KHz) of a femtosecond laser compared with flaps formed with a microkeratome...
  10. pmc Effect of femtosecond laser energy level on corneal stromal cell death and inflammation
    Fabricio Witzel de Medeiros
    Cleveland Clinic, Cole Eye Institute, Ohio 44195, USA
    J Refract Surg 25:869-74. 2009
    ..To analyze the effects of variations in femtosecond laser energy level on corneal stromal cell death and inflammatory cell influx following flap creation in a rabbit model...
  11. pmc Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea
    W Michael Stapleton
    Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Exp Eye Res 86:753-7. 2008
    ..Topical IL-1 receptor antagonist could be an effective adjuvant for clinical treatment of corneal conditions in which unwanted inflammation has a role in the pathophysiology of the disorder...
  12. pmc Corneal myofibroblast generation from bone marrow-derived cells
    Flavia L Barbosa
    Cole Eye Institute, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Exp Eye Res 91:92-6. 2010
    ..This model, therefore, cannot exclude the possibility of myofibroblasts also developed from keratocytes and/or corneal fibroblasts...
  13. pmc Corneal myofibroblast viability: opposing effects of IL-1 and TGF beta1
    Harmeet Kaur
    Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Exp Eye Res 89:152-8. 2009
    ..TGF beta1 and IL-1 have opposing effects on myofibroblast viability and likely interact to modulate haze generation after corneal injury...
  14. ncbi request reprint Haze development after photorefractive keratectomy: mechanical vs ethanol epithelial removal in rabbits
    Fabricio Witzel de Medeiros
    Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 24:923-7. 2008
    ..To compare mechanical and ethanol epithelial removal with respect to myofibroblast development and haze formation after photorefractive keratectomy (PRK)...
  15. pmc Corneal stroma PDGF blockade and myofibroblast development
    Harmeet Kaur
    Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Exp Eye Res 88:960-5. 2009
    ..Stromal PDGF-B blockade during the early postoperative period following PRK decreases stromal alphaSMA+ myofibroblast generation. PDGF is an important modulator of myofibroblast development in the cornea...
  16. pmc A novel method for generating corneal haze in anterior stroma of the mouse eye with the excimer laser
    Rajiv R Mohan
    Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Exp Eye Res 86:235-40. 2008
    ..This PTK technique for inducing haze in mouse cornea in vivo provides a useful model for studying wound healing and myofibroblast biology in transgenic mice...
  17. pmc Stromal haze, myofibroblasts, and surface irregularity after PRK
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Exp Eye Res 82:788-97. 2006
    ..Late apoptosis appears to have a role in the disappearance of myofibroblasts and haze over time...
  18. pmc Mouse strain variation in SMA(+) myofibroblast development after corneal injury
    Vivek Singh
    The Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Exp Eye Res 115:27-30. 2013
    ..Further investigation of genetics underlying mouse strain variation could provide insight into the corneal wound healing and haze generation processes. ..
  19. pmc Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 22:562-74. 2006
    ..To determine the mechanism through which topical mitomycin C prevents and treats corneal haze after photorefractive keratectomy (PRK) and to examine the effects of dosage and duration of exposure...
  20. pmc Transmission electron microscopy analysis of epithelial basement membrane repair in rabbit corneas with haze
    André A M Torricelli
    Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Invest Ophthalmol Vis Sci 54:4026-33. 2013
    ..To assess the ultrastructure of the epithelial basement membrane using transmission electron microscopy (TEM) in rabbit corneas with and without subepithelial stroma opacity (haze)...
  21. ncbi request reprint Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, OH 44195, USA
    Cornea 24:509-22. 2005
    ..The purpose of this review is to provide an overview of the healing response in refractive surgery procedures...
  22. doi request reprint Biological and biomechanical responses to traditional epithelium-off and transepithelial riboflavin-UVA CXL techniques in rabbits
    Brian K Armstrong
    Cole Eye Institute, and Quantiative Health Sciences, Cleveland Clinic, OH, USA
    J Refract Surg 29:332-41. 2013
    ..Preliminary experiments on biomechanical rigidity were also performed...
  23. doi request reprint Short-term cell death and inflammation after intracorneal inlay implantation in rabbits
    Marcony R Santhiago
    The Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 28:144-9. 2012
    ..To investigate the cell death and inflammatory response to insertion of the KAMRA inlay (AcuFocus Inc) for presbyopia...
  24. doi request reprint Dry eye associated with laser in situ keratomileusis: Mechanical microkeratome versus femtosecond laser
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 35:1756-60. 2009
    ..To compare the incidence of laser in situ keratomileusis (LASIK)-associated dry eye and the need for postoperative cyclosporine A treatment after flap creation with a femtosecond laser and a mechanical microkeratome...
  25. ncbi request reprint Wavefront analysis comparison of LASIK outcomes with the femtosecond laser and mechanical microkeratomes
    Fabricio W Medeiros
    Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    J Refract Surg 23:880-7. 2007
    ..To evaluate differences related to ocular aberrations after customized LASIK for myopia using three different microkeratomes...
  26. doi request reprint Corneal wound healing after ultraviolet-A/riboflavin collagen cross-linking: a rabbit study
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 27:401-7. 2011
    ..To investigate corneal wound healing following ultraviolet-A (UVA)/riboflavin corneal collagen cross-linking (CXL) in rabbit corneas...
  27. ncbi request reprint Flap lift for LASIK retreatment in eyes with myopia
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Ophthalmology 111:1362-7. 2004
    ..To analyze the results achieved with LASIK retreatment after lifting the original flap in a large series of patients...
  28. pmc Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury
    Shyam S Chaurasia
    Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Exp Eye Res 89:133-9. 2009
    ..The earliest precursors of myofibroblasts destined to express SMA and desmin are detectible by staining for vimentin at 1 week after surgery...
  29. pmc Differences in the early biomechanical effects of hyperopic and myopic laser in situ keratomileusis
    Fabricio Witzel de Medeiros
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 36:947-53. 2010
    ....
  30. doi request reprint Flap relift for retreatment after femtosecond laser-assisted LASIK
    Marcony R Santhiago
    The Cleveland Clinic, Cleveland, OH, USA
    J Refract Surg 28:482-7. 2012
    ..To analyze the results of LASIK retreatment performed by relifting the original femtosecond laser-created flap...
  31. doi request reprint Mitomycin C: biological effects and use in refractive surgery
    Marcony R Santhiago
    The Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Cornea 31:311-21. 2012
    ..To provide an overview of the safety and efficacy of mitomycin C (MMC) as adjuvant therapy after refractive surgery procedures...
  32. doi request reprint Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery
    Ravindra A Shah
    The Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Curr Opin Ophthalmol 21:269-73. 2010
    ..This review will highlight our understanding of the utility, mechanism of action, and safety profile of MMC...
  33. doi request reprint Femtosecond laser in laser in situ keratomileusis
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 36:1024-32. 2010
    ..In this article, we review common considerations in management and complications of this step in femtosecond laser-LASIK and concentrate primarily on the IntraLase laser because most published studies relate to this instrument...
  34. ncbi request reprint Wavefront-guided ablation: evidence for efficacy compared to traditional ablation
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA, and Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil
    Am J Ophthalmol 141:360-368. 2006
    ..To provide an evidence-based overview of wavefront-guided refractive surgery outcomes, benefits, and limitations...
  35. pmc A method to generate enhanced GFP+ chimeric mice to study the role of bone marrow-derived cells in the eye
    Vivek Singh
    Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Exp Eye Res 116:366-70. 2013
    ..The GFP+ bone marrow chimeric mouse provides an excellent model for studying the role of bone marrow-derived cells in corneal wound healing, glaucoma surgery, optic nerve head pathology and retinal pathophysiology and wound healing. ..
  36. doi request reprint Modulation transfer function and optical quality after bilateral implantation of a +3.00 D versus a +4.00 D multifocal intraocular lens
    Marcony R Santhiago
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44114, USA
    J Cataract Refract Surg 38:215-20. 2012
    ..00 diopter (D) addition (add) occurs at the expense of optical quality compared with the previous model with a +4.00 D add...
  37. ncbi request reprint Wavefront analysis in normal refractive surgery candidates
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    J Refract Surg 21:332-8. 2005
    ..To quantify the higher order aberrations of refractive surgery candidates and compare the wavefront-determined refractions with manifest refractions refined with a +/- 0.25 Jackson cross cylinder...
  38. pmc The corneal epithelial basement membrane: structure, function, and disease
    André A M Torricelli
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
    Invest Ophthalmol Vis Sci 54:6390-400. 2013
    ..The corneal epithelial BM is also involved in many inherited and acquired corneal diseases. This review examines this structure in detail and discusses the importance of corneal epithelial BM in homeostasis, wound healing, and disease...
  39. ncbi request reprint Gene therapy in the cornea
    Rajiv R Mohan
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Ave, Mail Code i 31, Cleveland, OH 44195, USA
    Prog Retin Eye Res 24:537-59. 2005
    ..We will review the successes and obstacles impeding gene therapy approaches used for delivering genes into the cornea...
  40. doi request reprint Cellular effects after laser in situ keratomileusis flap formation with femtosecond lasers: a review
    Marcony R Santhiago
    Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Cornea 31:198-205. 2012
    ..To provide an overview of the cellular effects of femtosecond laser in laser in situ keratomileusis flap formation...
  41. doi request reprint Visual performance of an apodized diffractive multifocal intraocular lens with +3.00-d addition: 1-year follow-up
    Marcony R Santhiago
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44114, USA
    J Refract Surg 27:899-906. 2011
    ..00 diopters [D]) at the lens plane results in better intermediate visual acuity 1 year after surgery compared with a multifocal IOL with higher addition (+4.00 D)...
  42. ncbi request reprint Corneal wound healing relevance to wavefront guided laser treatments
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 17:225-31, vii. 2004
    ....
  43. ncbi request reprint Indications for excimer laser surface ablation
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Refract Surg 21:734-41. 2005
  44. ncbi request reprint Reprint of "Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury"
    Shyam S Chaurasia
    Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Exp Eye Res 89:590-6. 2009
    ..The earliest precursors of myofibroblasts destined to express SMA and desmin are detectable by staining for vimentin at 1 week after surgery...
  45. pmc Biomechanics and wound healing in the cornea
    William J Dupps
    The Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, OH 44195, USA
    Exp Eye Res 83:709-20. 2006
    ....
  46. pmc Corneal molecular and cellular biology update for the refractive surgeon
    Marcella Q Salomao
    The Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 25:459-66. 2009
    ..To review clinically relevant progress in understanding cellular and molecular interactions in the cornea that relate to refractive surgical outcomes in patients...
  47. ncbi request reprint [Corneal wound healing response following different modalities of refractive surgical procedures]
    Marcelo Vieira Netto
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA
    Arq Bras Oftalmol 68:140-9. 2005
    ..The present text proposes a review of the corneal wound healing characteristics following different modalities of refractive surgical procedures...
  48. pmc Expression of PDGF receptor-alpha in corneal myofibroblasts in situ
    Harmeet Kaur
    Cole Eye Institute, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Exp Eye Res 89:432-4. 2009
    ..In vitro studies have suggested that PDGF is important in the development and viability of myofibroblasts after corneal injury. Expression of PDGFR-alpha in myofibroblasts supports these findings...
  49. ncbi request reprint Agreement of physician treatment practices with the international task force guidelines for diagnosis and treatment of dry eye disease
    Steven E Wilson
    Cleveland Clinic Cole Eye Institute, Cleveland, OH, USA
    Cornea 26:284-9. 2007
    ..To evaluate the clinical implementation of guidelines for the treatment of dysfunctional tear syndrome (DTS) developed by the International Task Force (ITF) of dry eye disease experts...
  50. doi request reprint The association between femtosecond laser flap parameters and ocular aberrations after uncomplicated custom myopic LASIK
    Christopher T Hood
    Cleveland Clinic Cole Eye Institute, Cleveland, OH, 44195, USA
    Graefes Arch Clin Exp Ophthalmol 251:2155-62. 2013
    ..To investigate the association between femtosecond laser flap parameters, uncorrected distance visual acuity, and higher-order aberrations (HOA) after customized myopic LASIK...
  51. ncbi request reprint Inflammation: a unifying theory for the origin of dry eye syndrome
    Steven E Wilson
    Cole Eye Institute, Cleveland Clinic Foundation, USA
    Manag Care 12:14-9. 2003
    ..An inflammatory mechanism apparently underlies the condition. This theory has been proven by use of immunomodulators that show efficacy in treating patients with dry eye syndrome...
  52. ncbi request reprint Corneal cells: chatty in development, homeostasis, wound healing, and disease
    Steven E Wilson
    Department of Ophthalmology, University of Washington, Seattle, Washington 98195, USA
    Am J Ophthalmol 136:530-6. 2003
    ..To provide an overview of cell-cell interactions in the cornea that have a critical role in corneal development, homeostasis, wound healing, and disease...
  53. ncbi request reprint Wave-front analysis: are we missing something?
    Steven E Wilson
    Am J Ophthalmol 136:340-2. 2003
  54. ncbi request reprint Corneal injury. A relatively pure model of stromal-epithelial interactions in wound healing
    Steven E Wilson
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, WA, USA
    Methods Mol Med 78:67-81. 2003
  55. ncbi request reprint Bilateral marginal sterile infiltrates and diffuse lamellar keratitis after laser in situ keratomileusis
    Renato Ambrosio
    Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA
    J Refract Surg 19:154-8. 2003
    ..To report cases of acute bilateral catarrhal infiltrates in the early postoperative period after laser in situ keratomileusis (LASIK)...
  56. ncbi request reprint Apoptosis in the cornea in response to epithelial injury: significance to wound healing and dry eye
    Steven E Wilson
    The Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington, USA
    Adv Exp Med Biol 506:821-6. 2002
  57. ncbi request reprint Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK
    Rahul R Mohan
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98195 6485, USA
    Exp Eye Res 76:71-87. 2003
    ....
  58. ncbi request reprint Gene transfer into rabbit keratocytes using AAV and lipid-mediated plasmid DNA vectors with a lamellar flap for stromal access
    Rajiv R Mohan
    Department of Ophthalmology, University of Washington School of Medicine, Box 356485, Seattle, WA 98195 6485, USA
    Exp Eye Res 76:373-83. 2003
    ..This is the first report to demonstrate selective gene transfer into keratocytes and would be highly useful in studying function and regulation of genes in vivo and may eventually furnish a tool for the treatment of corneal dystrophies...
  59. ncbi request reprint Effect of ectopic epithelial tissue within the stroma on keratocyte apoptosis, mitosis, and myofibroblast transformation
    Steven E Wilson
    Department of Ophthalmology, University of Washington School of Medicine, Box 356485, 1959 Pacific Street, Seattle, WA 98195 6485, USA
    Exp Eye Res 76:193-201. 2003
    ..Epithelium-derived signals also participate in the generation and/or maintenance of myofibroblasts in the corneal stroma...
  60. ncbi request reprint Corneal topographic and pachymetric screening of keratorefractive patients
    Renato Ambrosio
    Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA
    J Refract Surg 19:24-9. 2003
    ..To review the incidence of corneal abnormalities detected in the preoperative examination, using videokeratography and pachymetry that excluded patients from laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK)...
  61. pmc Analysis of the keratocyte apoptosis, keratocyte proliferation, and myofibroblast transformation responses after photorefractive keratectomy and laser in situ keratomileusis
    Steven E Wilson
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, USA
    Trans Am Ophthalmol Soc 100:411-33. 2002
    ....
  62. ncbi request reprint Correlation of pupil sizes measured with a mesopic infrared pupillometer and a photopic topographer
    Laura M Periman
    Department of Ophthalmology, University of Washington, Seattle 98195, USA
    J Refract Surg 19:555-9. 2003
    ..To determine if videokeratography-based pupil measurements are an accurate method of estimating pupil size under mesopic conditions...
  63. ncbi request reprint Influence of intraoperative epithelial defects on outcomes in LASIK for myopia
    Matthew S Oliva
    Department of Ophthalmology, University of Washington Seattle, Washington, USA
    Am J Ophthalmol 137:244-9. 2004
    ..To evaluate whether intraoperative epithelial defects have an adverse effect on achieving desired refractive outcomes following laser in situ keratomileusis (LASIK) for myopia...
  64. ncbi request reprint LASIK-associated dry eye and neurotrophic epitheliopathy: pathophysiology and strategies for prevention and treatment
    Renato Ambrosio
    Department of Ophthalmology, Fluminense Federal University, Niteroi, Brazil
    J Refract Surg 24:396-407. 2008
    ..To review the pathophysiology of LASIK-associated dry eye conditions and provide insights into prophylaxis to decrease the incidence of dry eye after LASIK and to treat the condition when it occurs...
  65. ncbi request reprint Management of unsuccessful LASIK surgery
    Renato Ambrosio
    Instituto de Olhos Renato Ambrosio, Visare Personal Laser and Refracta RIO, Rio de Janeiro, Brazil
    Compr Ophthalmol Update 8:125-41; discussion 143-4. 2007
    ..This paper reviews the management of unsuccessful laser-assisted in situ keratomileusis (LASIK) procedures, focusing on significant advances related to wavefront-guided therapeutic ablations...
  66. ncbi request reprint Dry eye and corneal sensitivity after high myopic LASIK
    Ilpo S Tuisku
    Helsinki University Eye Hospital, Helsinki, Finland
    J Refract Surg 23:338-42. 2007
    ..To assess subjective symptoms and objective clinical signs of dry eye and investigate corneal sensitivity after high myopic LASIK...
  67. pmc Loss of alpha3(IV) collagen expression associated with corneal keratocyte activation
    Emily Guerriero
    UPMC Eye Center, Ophthalmology and Visual Science Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Invest Ophthalmol Vis Sci 48:627-35. 2007
    ..To determine whether changes in the expression of type IV alpha1, alpha2, or alpha3 collagen isoforms are stringently associated with corneal stromal cell activation...
  68. ncbi request reprint Pellucid marginal corneal degeneration
    Júnior Renato Ambrósio
    J Refract Surg 18:86-8. 2002
  69. ncbi request reprint Early pellucid marginal corneal degeneration: case reports of two refractive surgery candidates
    Renato Ambrosio
    Department of Ophthalmology, University of Washington, Seattle 98195, USA
    Cornea 21:114-7. 2002
    ..To report two refractive surgery candidates who demonstrated early corneal topographic findings of pellucid marginal degeneration...
  70. ncbi request reprint Surgery in patients with Fuchs'
    Renato Ambrosio
    Ophthalmology 113:503; author reply 504. 2006
  71. ncbi request reprint Refractive surgery and cornea: the never-ending spiral of technology
    Steven E Wilson
    Arch Ophthalmol 123:265-6. 2005
  72. ncbi request reprint Pupil size in refractive surgery candidates
    Marcelo V Netto
    Department of Ophthalmology, University of Washington, Seattle, WA, USA
    J Refract Surg 20:337-42. 2004
    ..To assess pupil size measurements obtained under scotopic and mesopic conditions with the Procyon pupillometer and under photopic conditions with the Humphrey videokeratographer...
  73. ncbi request reprint Development of genetically engineered tet HPV16-E6/E7 transduced human corneal epithelial clones having tight regulation of proliferation and normal differentiation
    Rajiv R Mohan
    Department of Ophthalmology, School of Medicine, University of Washington, Seattle 98195 6485, USA
    Exp Eye Res 77:395-407. 2003
    ..The physical barrier established by the newly developed clones was determined by the transepithelial permeability to sodium fluorescein and transepithelial electrical resistance assays in the airlifted-stratified cultures...
  74. ncbi request reprint Sporadic diffuse lamellar keratitis (DLK) after LASIK
    Steven E Wilson
    Department of Ophthalmology, University of Washington School of Medicine, Box 356485, Seattle, WA 98195 6485, USA
    Cornea 21:560-3. 2002
    ..To examine the incidence of sporadic diffuse lamellar keratitis (DLK) in a large series of LASIK eyes and to suggest the hypothesis that the etiology of sporadic DLK differs from that of epidemic DLK...
  75. ncbi request reprint Dysfunctional tear syndrome: a Delphi approach to treatment recommendations
    Ashley Behrens
    Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287 9278, USA
    Cornea 25:900-7. 2006
    ..To develop current treatment recommendations for dry eye disease from consensus of expert advice...

Research Grants14

  1. Corneal Epithelial Growth Factors and Receptors
    Steven Wilson; Fiscal Year: 2009
    ..The research design is histopathologic, cellular, and molecular investigations in corneas and cultured cells from animal models. ..
  2. Corneal Epithelial Growth Factors and Receptors
    Steven Wilson; Fiscal Year: 2007
    ..The research design is histopathologic, cellular, and molecular investigations in corneas and cultured cells from animal models. ..
  3. CORNEAL EPITHELIAL CELL GROWTH FACTORS AND RECEPTORS
    Steven Wilson; Fiscal Year: 2004
    ....
  4. CORNEAL EPITHELIAL CELL GROWTH FACTORS AND RECEPTORS
    Steven Wilson; Fiscal Year: 1999
    ....
  5. Corneal Epithelial Growth Factors and Receptors
    Steven E Wilson; Fiscal Year: 2010
    ..The research design is histopathological, cellular, and molecular investigations in corneas and cultured cells from animal models. ..