Ken Uchino

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. doi request reprint Stroke Legislation Impacts Distribution of Certified Stroke Centers in the United States
    Ken Uchino
    From the Cerebrovascular Center, Neurological Insitute K U, S M, I L K and Department of Quantitative Health Sciences J D S, Cleveland Clinic, OH
    Stroke 46:1903-8. 2015
  2. pmc Does the sex of acute stroke patients influence the effectiveness of rt-PA?
    Fawaz Al-Hussain
    Department of Medicine, King Saud University, Riyadh, Saudi Arabia
    BMC Neurol 14:60. 2014
  3. pmc Paroxysmal rhinorrhea after medullary infarct
    Ken Uchino
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA
    Case Rep Neurol 4:28-30. 2012
  4. doi request reprint Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials
    Ken Uchino
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Ave, Mail Code S80, Cleveland, OH 44195, USA
    Arch Intern Med 172:397-402. 2012
  5. doi request reprint Protocol adherence and safety of intravenous thrombolysis after telephone consultation with a stroke center
    Ken Uchino
    University of Pittsburgh Medical Center Stroke Institute, Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Stroke Cerebrovasc Dis 19:417-23. 2010
  6. doi request reprint Transient ischemic attack after tissue plasminogen activator: aborted stroke or unnecessary stroke therapy?
    Ken Uchino
    UPMC Stroke Institute, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Cerebrovasc Dis 29:57-61. 2010
  7. doi request reprint Lower pretreatment cerebral blood volume affects hemorrhagic risks after intra-arterial revascularization in acute stroke
    Archit Bhatt
    Department of Neurology, Division of Cerebrovascular Diseases, Michigan State University, East Lansing, Michigan, USA
    Neurosurgery 63:874-8; discussion 878-9. 2008
  8. ncbi request reprint Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation
    Rishi Gupta
    Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stroke 37:2562-6. 2006
  9. ncbi request reprint Multimodal reperfusion therapy for acute ischemic stroke: factors predicting vessel recanalization
    Rishi Gupta
    Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, Pennsylvania, USA
    Stroke 37:986-90. 2006
  10. ncbi request reprint Reduced pretreatment ipsilateral middle cerebral artery cerebral blood flow is predictive of symptomatic hemorrhage post-intra-arterial thrombolysis in patients with middle cerebral artery occlusion
    Rishi Gupta
    Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Stroke 37:2526-30. 2006

Detail Information

Publications38

  1. doi request reprint Stroke Legislation Impacts Distribution of Certified Stroke Centers in the United States
    Ken Uchino
    From the Cerebrovascular Center, Neurological Insitute K U, S M, I L K and Department of Quantitative Health Sciences J D S, Cleveland Clinic, OH
    Stroke 46:1903-8. 2015
    ....
  2. pmc Does the sex of acute stroke patients influence the effectiveness of rt-PA?
    Fawaz Al-Hussain
    Department of Medicine, King Saud University, Riyadh, Saudi Arabia
    BMC Neurol 14:60. 2014
    ..To investigate this we studied a series of stroke patients receiving IV rt-PA and undergoing acute transcranial doppler (TCD) examination...
  3. pmc Paroxysmal rhinorrhea after medullary infarct
    Ken Uchino
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA
    Case Rep Neurol 4:28-30. 2012
    ..We report a case of unilateral intermittent rhinorrhea that started after an ischemic stroke in the ipsilateral lateral medulla and cerebellum. Rhinorrhea might be mediated by dysfunction of the sympathetic autonomic system...
  4. doi request reprint Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials
    Ken Uchino
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Ave, Mail Code S80, Cleveland, OH 44195, USA
    Arch Intern Med 172:397-402. 2012
    ..We systematically evaluated the risk of MI or acute coronary syndrome (ACS) with the use of dabigatran...
  5. doi request reprint Protocol adherence and safety of intravenous thrombolysis after telephone consultation with a stroke center
    Ken Uchino
    University of Pittsburgh Medical Center Stroke Institute, Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Stroke Cerebrovasc Dis 19:417-23. 2010
    ..Our findings indicate the need for improved protocol adherence for stroke thrombolysis in patients presenting to small community hospitals...
  6. doi request reprint Transient ischemic attack after tissue plasminogen activator: aborted stroke or unnecessary stroke therapy?
    Ken Uchino
    UPMC Stroke Institute, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Cerebrovasc Dis 29:57-61. 2010
    ..The frequency with which intravenous thrombolysis for acute ischemic stroke results in normal clinical and radiographic status is currently unknown...
  7. doi request reprint Lower pretreatment cerebral blood volume affects hemorrhagic risks after intra-arterial revascularization in acute stroke
    Archit Bhatt
    Department of Neurology, Division of Cerebrovascular Diseases, Michigan State University, East Lansing, Michigan, USA
    Neurosurgery 63:874-8; discussion 878-9. 2008
    ..We sought to determine whether pretreatment computed tomography perfusion parameters might help to identify patients at a higher risk of developing intracranial hemorrhage after intra-arterial stroke revascularization treatment...
  8. ncbi request reprint Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation
    Rishi Gupta
    Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stroke 37:2562-6. 2006
    ..We report our technical success rate and short-term restenosis rates after stenting with DESs in the intracranial and extracranial circulation...
  9. ncbi request reprint Multimodal reperfusion therapy for acute ischemic stroke: factors predicting vessel recanalization
    Rishi Gupta
    Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, Pennsylvania, USA
    Stroke 37:986-90. 2006
    ..Endovascular therapies using mechanical and pharmacological modalities for large vessel occlusions in acute stroke are rapidly evolving. Our aim was to determine whether one modality is associated with higher recanalization rates...
  10. ncbi request reprint Reduced pretreatment ipsilateral middle cerebral artery cerebral blood flow is predictive of symptomatic hemorrhage post-intra-arterial thrombolysis in patients with middle cerebral artery occlusion
    Rishi Gupta
    Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Stroke 37:2526-30. 2006
    ..We hypothesized that patients with lower prethrombolysis cerebral blood flow (CBF) were at a higher risk of symptomatic ICH (sICH)...
  11. doi request reprint Telemedicine in Prehospital Stroke Evaluation and Thrombolysis: Taking Stroke Treatment to the Doorstep
    Ahmed Itrat
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio
    JAMA Neurol 73:162-8. 2016
    ..These units can be made more resource efficient if the need for an on-site neurologist can be eliminated by relying solely on telemedicine for physician presence...
  12. doi request reprint Addition of hyperacute MRI AIDS in patient selection, decreasing the use of endovascular stroke therapy
    Dolora Wisco
    From the Cerebrovascular Center, Neurological Institute D W, K U, J G, S A, P G, C R N, S M, J M, M W, E C C, F H, G T, M B, P R, M S H and Imaging Institute T M, P R, Cleveland Clinic, OH Division of Neurology, University of Alberta, Edmonton, Canada M S Department of Stroke Medicine, Kawasaki Medical School, Kurashiki, Japan J A and Cerebrovascular Center, Nagasaki University Hospital, Nagasaki City, Japan Y T
    Stroke 45:467-72. 2014
    ..We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection...
  13. doi request reprint The location of pretreatment hyperdense middle cerebral artery sign predicts the outcome of intraarterial thrombectomy for acute stroke
    Shumei Man
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH
    J Neuroimaging 25:263-8. 2015
    ..We aimed to investigate whether hyperdense middle cerebral artery sign (HMCAS) on preintervention nonenhanced CT (NECT) predicts IA therapy outcome for acute stroke...
  14. doi request reprint Predictors of infarct growth after endovascular therapy for acute ischemic stroke
    Shumei Man
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio
    J Stroke Cerebrovasc Dis 24:401-7. 2015
    ..The core infarct also grows at a variable rate despite recanalization. We aim to study the factors that are associated with infarct growth after IA therapy...
  15. doi request reprint Endovascular treatment of basilar artery occlusion by manual aspiration thrombectomy
    Brian T Jankowitz
    Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Neurointerv Surg 2:110-4. 2010
    ..Intravenous and intra-arterial therapy have altered the natural history of this disease; however, clinical results remain poor. Therefore, exploring more aggressive and innovative management is warranted...
  16. doi request reprint Mechanical approaches combined with intra-arterial pharmacological therapy are associated with higher recanalization rates than either intervention alone in revascularization of acute carotid terminus occlusion
    Ridwan Lin
    Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, Pittsburgh, PA 15213, USA
    Stroke 40:2092-7. 2009
    ..Historically, pharmacological thrombolysis alone has low recanalization rates. We sought to determine whether adjunctive mechanical approaches achieve better vessel recanalization and functional outcome...
  17. doi request reprint Diffusion-weighted imaging volume as the best predictor of the diffusion-perfusion mismatch in acute stroke patients within 8 hours of onset
    Junya Aoki
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Ohio
    J Neuroimaging 25:217-25. 2015
    ..Diagnostic accuracies of standard NCCT, CTA, CTA-SI, FLAIR, and DWI to detect the diffusion-perfusion mismatch (DPM) were compared...
  18. doi request reprint Post-intervention TCD examination may be useful to predict outcome in acute ischemic stroke patients with successful intra-arterial intervention
    Junya Aoki
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, OH, USA Electronic address
    J Neurol Sci 334:26-9. 2013
    ..Some acute stoke patients have a poor outcome despite successful arterial recanalization. We hypothesized that transcranial Doppler (TCD) findings from the rescued artery might predict poor outcome in patients with recanalization...
  19. ncbi request reprint Aortic dissection presenting as an acute ischemic stroke for thrombolysis
    Ken Uchino
    Department of Neurology, University of Texas Houston Medical School, Houston, TX, USA
    J Neuroimaging 15:281-3. 2005
    ..An experienced sonographer with skills to perform rapid intra- and extracranial examinations may help to change the treatment plan for acute stroke patients...
  20. doi request reprint Collateral flow and brain changes on computed tomography angiography predict infarct volume on early diffusion-weighted imaging
    Junya Aoki
    Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio Electronic address
    J Stroke Cerebrovasc Dis 23:2845-50. 2014
    ..We investigated whether a computed tomography (CT)-based score could predict a large infarct (≥ 80 mL) on early diffusion-weighted magnetic resonance imaging (DWI)...
  21. doi request reprint Platelet C4d is associated with acute ischemic stroke and stroke severity
    Nidhi Mehta
    University of Pittsburgh School of the Health Sciences, University of Pittsburgh, PA, USA
    Stroke 39:3236-41. 2008
    ..We compared the prevalence of platelet C4d and investigated the clinical associations of platelet C4d in patients with acute ischemic stroke...
  22. ncbi request reprint Quantitative perihematomal blood flow in spontaneous intracerebral hemorrhage predicts in-hospital functional outcome
    Ashis H Tayal
    Department of Neurology and University of Pittsburgh Medical Center Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Stroke 38:319-24. 2007
    ..We correlated perihematomal CBF in a retrospective series of 42 subacute spontaneous intracerebral hemorrhage patients undergoing xenon computed tomography with in-hospital discharge status and mortality...
  23. ncbi request reprint Emergent stenting of extracranial internal carotid artery occlusion in acute stroke has a high revascularization rate
    Tudor G Jovin
    Department of Neurology, University of Pittsburgh Medical Center Stroke Institute, Pittsburgh, PA 15213, USA
    Stroke 36:2426-30. 2005
    ..In selected cases, revascularization with carotid artery stenting has been reported, but the safety, recanalization rate, and clinical outcomes in consecutive case series are not known...
  24. doi request reprint Brain Imaging Using Mobile CT: Current Status and Future Prospects
    Seby John
    Cerebrovascular Center, Cleveland Clinic, Cleveland, OH
    J Neuroimaging 26:5-15. 2016
    ..In this review, we discuss the development of mobile CT and its applications, with specific focus on its use in MSUs along with our institution's MSU experience. ..
  25. ncbi request reprint Argatroban tPA stroke study: study design and results in the first treated cohort
    Rebecca M Sugg
    Department of Neurology, University of Texas Houston Medical School, 6431 Fannin, Houston, TX 77030, USA
    Arch Neurol 63:1057-62. 2006
    ..Argatroban is a direct thrombin inhibitor that safely augments the benefit of rtPA in animal stroke models. There are no human data on this combination...
  26. doi request reprint A Mobile Stroke Treatment Unit for Field Triage of Patients for Intraarterial Revascularization Therapy
    Russell Cerejo
    Cerebrovascular Center, Cleveland Clinic, Cleveland, OH
    J Neuroimaging 25:940-5. 2015
    ..The mobile stroke treatment unit (MSTU) is an on-site, prehospital, treatment team, laboratory, and CT scanner that reduces time to treatment for intravenous thrombolysis and may also shorten time to IAT...
  27. doi request reprint Electronic Stroke CarePath: Integrated Approach to Stroke Care
    Irene L Katzan
    From the Center for Outcomes Research and Evaluation, Neurological Institute I L K, Y F, S D G, M M, Information Technology Division, Clinical Systems Office I L K, L F, J U, Cerebrovascular Center, Neurological Institute I L K, K U, M M, and Lerner Research Institute, Quantitative Health Sciences Y F, S D G, Cleveland Clinic, OH and Speck Technologies, Cleveland, OH M S
    Circ Cardiovasc Qual Outcomes 8:S179-89. 2015
    ..Implementation of the Electronic Stroke CarePath is feasible and may be associated with a benefit in multiple different outcomes after ischemic stroke. This approach may be an important strategy for optimizing stroke care in the future. ..
  28. doi request reprint Intra-arterial therapy for acute ischemic stroke under general anesthesia versus monitored anesthesia care
    Seby John
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA
    Cerebrovasc Dis 38:262-7. 2014
    ..The reasons for this association have not been systematically studied...
  29. pmc High-resolution MRI vessel wall imaging in varicella zoster virus vasculopathy
    Esteban Cheng-Ching
    Department of Neuroradiology, Imaging Institute, Cleveland Clinic, Cleveland, OH, USA
    J Neurol Sci 351:168-73. 2015
    ..Follow-up HRMR showed improvement of stenosis, with reduced vessel wall thickening and enhancement at multiple times after treatment. HRMR has the potential to assist in diagnosis and treatment of VZV vasculopathy. ..
  30. pmc Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial
    William J Powers
    Department of Neurology, Box 7025, Room 2131, 170 Manning Dr, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    JAMA 306:1983-92. 2011
    ..Patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) and hemodynamic cerebral ischemia are at high risk for subsequent stroke when treated medically...
  31. ncbi request reprint Safety and feasibility of a lower dose intravenous TPA therapy for ischemic stroke beyond the first three hours
    Ken Uchino
    Stroke Program, Department of Neurology, University of Texas Houston Medical School, USA
    Cerebrovasc Dis 19:260-6. 2005
    ..The risk/benefit ratio is more unfavorable beyond this time, but some patients might still benefit. We designed a pilot study with the hypothesis that lower dose TPA might be safe in selected patients treated beyond 3 h...
  32. doi request reprint Last resort: case of clot translocation in intra-arterial stroke therapy
    Seby John
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA
    J Neurointerv Surg 6:e50. 2014
    ..While uncommon, strategies to overcome this are important to keep in mind during acute stroke intervention. ..
  33. doi request reprint Reversible cerebral vasoconstriction syndrome: Is it more than just cerebral vasoconstriction?
    Seby John
    Cerebrovascular Center, Cleveland Clinic, OH, USA
    Cephalalgia 35:631-4. 2015
    ..We present a case series of RCVS patients having cardiac dysfunction during ictus, with a subset showing complete resolution of cardiomyopathy...
  34. doi request reprint Early experience in high-resolution MRI for large vessel occlusions
    Ferdinand K Hui
    Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Neurointerv Surg 7:509-16. 2015
    ....
  35. doi request reprint The stroke 8: a daily checklist for inpatient stroke management
    Irene Katzan
    From the Neurological Institute, Cleveland Clinic, Cleveland, OH Speck Technologies, Cleveland, OH and Barrow Neurological Institute, Phoenix, AZ
    Crit Pathw Cardiol 14:1-6. 2015
    ..We have found the Stroke 8 to be a valuable tool in the daily inpatient management of patients with acute stroke. ..
  36. pmc Acute endovascular reperfusion therapy in ischemic stroke: a systematic review and meta-analysis of randomized controlled trials
    Toshiya Osanai
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 10:e0122806. 2015
    ..Randomized controlled trials (RCTs) of endovascular therapy for acute ischemic stroke have had inconsistent results. We evaluated the efficacy and safety of endovascular therapy in published RCTs...
  37. doi request reprint Centenarian middle cerebral artery occlusion treated with intra-arterial mechanical embolectomy
    Christopher L Cummings
    Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Neurointerv Surg 4:e23. 2012
    ..The patient improved, and ultimately returned to a baseline modified Rankin Scale score of 3. With careful selection, elderly patients may benefit from acute stroke therapies and may be considered on a case by case basis...
  38. ncbi request reprint Moyamoya disease in Washington State and California
    Ken Uchino
    Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Neurology 65:956-8. 2005
    ..2 (95% CI: 1.3 to 2.4) for African Americans, and 0.5 (95% CI: 0.3 to 0.8) for Hispanics. The incidence of moyamoya in Washington and California was lower than reported in Japan, but the rate among US Asians is similar...