James D Thomas

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. doi request reprint Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis
    Dermot Phelan
    Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Heart 98:1442-8. 2012
  2. pmc Predictors of mitral annulus early diastolic velocity: impact of long-axis function, ventricular filling pattern, and relaxation
    Zoran B Popovic
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Eur J Echocardiogr 12:818-25. 2011
  3. pmc Doppler echocardiographic assessment of valvar regurgitation
    James D Thomas
    Department of Cardiology, Desk F15, 9500 Euclid Avenue, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Heart 88:651-7. 2002
  4. doi request reprint Digital echocardiography: the guiding role of Harvey Feigenbaum
    James D Thomas
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 21:29-33. 2008
  5. ncbi request reprint Assessment of left ventricular function by cardiac ultrasound
    James D Thomas
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 48:2012-25. 2006
  6. ncbi request reprint Digital echocardiography 2002: now is the time
    James D Thomas
    Cardiovascular Imaging Center, Department of Cardiology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 15:831-8. 2002
  7. ncbi request reprint Determinants of recurrent or residual functional tricuspid regurgitation after tricuspid annuloplasty
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F15, Cleveland, Ohio 44195, USA
    Circulation 114:I582-7. 2006
  8. pmc Impact of left ventricular volume/mass ratio on diastolic function
    Adisai Buakhamsri
    Division of Cardiovascular Medicine, Department of Cardiology, Desk F 15, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Eur Heart J 30:1213-21. 2009
  9. ncbi request reprint The Coapsys device to treat functional mitral regurgitation: in vivo long-term canine study
    Masahiro Inoue
    Department of Bioengineering, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Thorac Cardiovasc Surg 127:1068-76; discussion 1076-7. 2004
  10. ncbi request reprint Usefulness of real-time three-dimensional echocardiography for evaluation of myectomy in patients with hypertrophic cardiomyopathy
    Jian Xin Qin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 94:964-6. 2004

Detail Information

Publications110 found, 100 shown here

  1. doi request reprint Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis
    Dermot Phelan
    Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Heart 98:1442-8. 2012
    ..The diagnosis of cardiac amyloidosis (CA) is challenging owing to vague symptomatology and non-specific echocardiographic findings...
  2. pmc Predictors of mitral annulus early diastolic velocity: impact of long-axis function, ventricular filling pattern, and relaxation
    Zoran B Popovic
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Eur J Echocardiogr 12:818-25. 2011
    ..Although left ventricular (LV) relaxation is well recognized as a predictor of mitral annulus (MA) early diastolic (E') velocity, its significance relative to other predictors of E' is less well understood...
  3. pmc Doppler echocardiographic assessment of valvar regurgitation
    James D Thomas
    Department of Cardiology, Desk F15, 9500 Euclid Avenue, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Heart 88:651-7. 2002
  4. doi request reprint Digital echocardiography: the guiding role of Harvey Feigenbaum
    James D Thomas
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 21:29-33. 2008
  5. ncbi request reprint Assessment of left ventricular function by cardiac ultrasound
    James D Thomas
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 48:2012-25. 2006
    ..This review also discusses the clinical impact of echocardiography and its future directions and developments...
  6. ncbi request reprint Digital echocardiography 2002: now is the time
    James D Thomas
    Cardiovascular Imaging Center, Department of Cardiology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 15:831-8. 2002
    ....
  7. ncbi request reprint Determinants of recurrent or residual functional tricuspid regurgitation after tricuspid annuloplasty
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F15, Cleveland, Ohio 44195, USA
    Circulation 114:I582-7. 2006
    ..The purpose of this study was to investigate echocardiographic determinants of mid-term outcome after TV annuloplasty...
  8. pmc Impact of left ventricular volume/mass ratio on diastolic function
    Adisai Buakhamsri
    Division of Cardiovascular Medicine, Department of Cardiology, Desk F 15, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Eur Heart J 30:1213-21. 2009
    ..To assess the impact of left ventricular (LV) volume/mass ratio on diastolic function parameters in subjects with dilated cardiomyopathy (DCM) or hypertrophic cardiomyopathy (HCM) and healthy controls...
  9. ncbi request reprint The Coapsys device to treat functional mitral regurgitation: in vivo long-term canine study
    Masahiro Inoue
    Department of Bioengineering, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Thorac Cardiovasc Surg 127:1068-76; discussion 1076-7. 2004
    ..We evaluated the capability of the Myocor Coapsys device (Myocor, Inc, Maple Grove, Minn) to reduce functional mitral regurgitation in a canine model of dilated cardiomyopathy...
  10. ncbi request reprint Usefulness of real-time three-dimensional echocardiography for evaluation of myectomy in patients with hypertrophic cardiomyopathy
    Jian Xin Qin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 94:964-6. 2004
    ..4 +/- 0.7 vs 5.1 +/- 1.2 cm(2), p <0.01), significantly increased after myectomy (4.8 +/- 1.8 cm2, p <0.01) and was associated with a reduction of the pressure gradient at rest from 63 +/- 41 to 15 +/- 5 mm Hg (p <0.01)...
  11. ncbi request reprint Impact of longitudinal cardiac rotation on mitral and tricuspid atrioventricular annular diastolic motion
    Zoran B Popovic
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Circ Cardiovasc Imaging 3:368-74. 2010
    ....
  12. ncbi request reprint Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction
    Zoran B Popovic
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 292:H2809-16. 2007
    ..0001) than on percent fibrosis (P<0.002). STE correctly identifies segmental LV dysfunction induced by scarring that follows myocardial infarction in rats...
  13. ncbi request reprint The pseudorestrictive pattern of transmitral Doppler flow pattern after conversion of atrial fibrillation to sinus rhythm: is atrial or ventricular dysfunction to blame?
    Hirotsugu Yamada
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 17:813-8. 2004
    ..Transient left ventricular diastolic dysfunction also effected the TMF velocity immediately after the conversion from AF to sinus rhythm, although it recovered faster than LA mechanical dysfunction...
  14. doi request reprint Diagnostic value of left ventricular outflow area in patients with hypertrophic cardiomyopathy: a real-time three-dimensional echocardiographic study
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 21:789-95. 2008
    ..However, its clinical value is unknown...
  15. doi request reprint Relation of ventricular-vascular coupling to exercise capacity in ischemic cardiomyopathy: a cardiac multi-modality imaging study
    Raymond C Wong
    Department of Cardiovascular Medicine F15, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA
    Int J Cardiovasc Imaging 26:151-9. 2010
    ..Ventricular-vascular coupling at rest may be a clinically important parameter in predicting exercise capacity in patients with advanced heart failure, and may become an additional target for therapeutic interventions...
  16. ncbi request reprint Use of strain imaging in detecting segmental dysfunction in patients with hypertrophic cardiomyopathy
    Hua Yang
    Department of Cardiology, The Cleveland Clinic Foundation, Clevelnad OH 44195, USA
    J Am Soc Echocardiogr 16:233-9. 2003
    ..The aim of this study was to characterize regional left ventricular systolic function by myocardial Doppler epsilon imaging in patients with HCM...
  17. ncbi request reprint Quantitative analysis of left atrial function during left ventricular ischemia with and without left atrial ischemia: a real-time 3-dimensional echocardiographic study
    Fabrice Bauer
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 18:795-801. 2005
    ....
  18. ncbi request reprint Ventricular untwisting: a temporal link between left ventricular relaxation and suction
    Yuichi Notomi
    Department of Cardiovascular Medicine F15, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 294:H505-13. 2008
    ..Untwisting rate may be a useful marker of diastolic function or even serve as a therapeutic target for improving diastolic function...
  19. doi request reprint Opposing wall mechanics are significantly influenced by longitudinal cardiac rotation in the assessment of ventricular dyssynchrony
    Karen P Phillips
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    JACC Cardiovasc Imaging 2:379-86. 2009
    ..This study sought to assess whether longitudinal rotation (LR) affects myocardial systolic velocity profiles and to compare velocity-based measures of dyssynchrony with LR for predicting cardiac resynchronization therapy (CRT) response...
  20. ncbi request reprint Frank-Starling mechanism contributes modestly to ventricular performance during atrial fibrillation
    Zoran B Popovic
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
    Heart Rhythm 1:482-9. 2004
    ..The aim of this study was to assess whether Frank-Starling mechanism has an independent effect on left ventricular (LV) performance in atrial fibrillation (AF)...
  21. ncbi request reprint Left ventricular outflow tract mean systolic acceleration as a surrogate for the slope of the left ventricular end-systolic pressure-volume relationship
    Fabrice Bauer
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 40:1320-7. 2002
    ..The goal of this study was to analyze left ventricular outflow tract systolic acceleration (LVOT(Acc)) during alterations in left ventricular (LV) contractility and LV filling...
  22. ncbi request reprint Mitral valve repair without cardiopulmonary bypass or atriotomy using the coapsys device: device design and implantation procedure in canine functional mitral regurgitation model
    Masahiro Inoue
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Ohio, USA
    Heart Surg Forum 7:E117-21. 2004
    ..This study was conducted to test the feasibility of the Coapsys implantation procedure in a canine functional MR model...
  23. ncbi request reprint Three-dimensional geometry of the tricuspid annulus in healthy subjects and in patients with functional tricuspid regurgitation: a real-time, 3-dimensional echocardiographic study
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Desk F15, Cleveland, Ohio 44195, USA
    Circulation 114:I492-8. 2006
    ..The purpose of this study was therefore to investigate the 3D geometry of the TA in healthy subjects and in patients with functional tricuspid regurgitation (TR)...
  24. ncbi request reprint Optimal mitral annular and subvalvular shape change created by the Coapsys device to treat functional mitral regurgitation
    Kiyotaka Fukamachi
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    ASAIO J 51:17-21. 2005
    ..The Coapsys device can be applied over a broad range of tightening levels with significant reduction in MR without negative physiologic impact. This feature makes the device usable [corrected] in a variety of clinical settings...
  25. doi request reprint Determination of regurgitant orifice area with the use of a new three-dimensional flow convergence geometric assumption in functional mitral regurgitation
    Yoshiki Matsumura
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Soc Echocardiogr 21:1251-6. 2008
    ..The underestimation by the hemispheric PISA method can be significantly corrected by our hemiellipsoidal method...
  26. ncbi request reprint Pulmonary venous flow determinants of left atrial pressure under different loading conditions in a chronic animal model with mitral regurgitation
    Hua Yang
    Cardiovascular Imaging Section, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Soc Echocardiogr 15:1181-8. 2002
    ....
  27. ncbi request reprint Conduction system abnormalities in patients with obstructive hypertrophic cardiomyopathy following septal reduction interventions
    Jian Xin Qin
    Department of Cardiovascular Medicine, Cleveland, Ohio 44195, USA
    Am J Cardiol 93:171-5. 2004
    ..0001). Thus, RBBB often develops after PTSMA and LBBB is very frequently produced by myectomy. A possible requirement of a permanent pacemaker should always be considered before intervention when patients have preexisting RBBB or LBBB...
  28. ncbi request reprint The accuracy of left ventricular mass determined by real-time three-dimensional echocardiography in chronic animal and clinical studies: a comparison with postmortem examination and magnetic resonance imaging
    Jian Xin Qin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 18:1037-43. 2005
    ..001). In the clinical study, RT3DE also provided the best concordance correlation with left ventricular mass determined by magnetic resonance imaging (0.91 for RT3DE, 0.83 for 2DE, and 0.38 for M-mode; P < .0001)...
  29. ncbi request reprint Determinants of LV diastolic function during atrial fibrillation: beat-to-beat analysis in acute dog experiments
    Tomotsugu Tabata
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 286:H145-52. 2004
    ..This suggests that the major benefit of slower ventricular rate appears related to lengthening of LV filling interval, promoting subsequent higher peak systolic LVP and greater LV relaxation...
  30. ncbi request reprint Mitral annulus size links ventricular dilatation to functional mitral regurgitation
    Zoran B Popovic
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 18:959-63. 2005
    ..68, P = .002). Mitral annulus dilation is the strongest predictor of functional mitral regurgitation in this animal dilated cardiomyopathy model...
  31. ncbi request reprint Real-time three-dimensional color doppler evaluation of the flow convergence zone for quantification of mitral regurgitation: Validation experimental animal study and initial clinical experience
    Marta Sitges
    Cardiovascular Imaging Center, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 16:38-45. 2003
    ..This limitation may be mitigated by the use of real-time 3D color Doppler echocardiography (CE). Our objective was to validate a real-time 3D navigation method for MR quantification...
  32. ncbi request reprint Determinants of the development of mitral regurgitation in pacing-induced heart failure
    Masami Takagaki
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, OH 44195, USA
    Circ J 67:78-82. 2003
    ..Many factors influence the development of MR and because of its similarity to the clinical situation, this model can be used to investigate MR and heart failure, as well as new surgical therapies...
  33. doi request reprint Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: a novel computerized 3D echocardiographic analysis
    Masao Daimon
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Echocardiography 25:414-23. 2008
    ....
  34. ncbi request reprint Electrical conduction disturbance effects on dynamic changes of functional mitral regurgitation
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 46:2270-6. 2005
    ....
  35. doi request reprint Doppler-derived preoperative mitral regurgitation volume predicts postoperative left ventricular dysfunction after mitral valve repair
    Tetsuhiro Yamano
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA
    Am Heart J 157:875-82. 2009
    ..Identification of factors that predispose to such LV dysfunction would enhance our understanding of the indications and outcomes of surgery...
  36. ncbi request reprint Asymmetry of systolic anterior motion of the mitral valve in patients with hypertrophic obstructive cardiomyopathy: a real-time three-dimensional echocardiographic study
    Jong Min Song
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 19:1129-35. 2006
    ..In conclusion, systolic anterior motion of the mitral valve develops predominantly in the medial side, resulting in laterally located narrow left ventricular outflow tract opening in patients with hypertrophic obstructive cardiomyopathy...
  37. pmc Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity
    Junko Asada-Kamiguchi
    Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Eur J Echocardiogr 10:826-32. 2009
    ..To elucidate the usefulness of the early diastolic mitral flow propagation velocity (V(p)) obtained from colour M-mode Doppler for non-invasively assessing left-ventricular (LV) relaxation during atrial fibrillation (AF)...
  38. ncbi request reprint Incremental prognostic value of diastolic dysfunction in low risk patients undergoing echocardiography: beyond Framingham score
    Wael A AlJaroudi
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA
    Int J Cardiovasc Imaging 29:1441-50. 2013
    ..6 [1.25; 5.55], p = 0.01). In low-risk adult outpatients undergoing echocardiography, DD was associated with 2-3 fold increase in risk of death and had incremental prognostic value beyond FRS...
  39. ncbi request reprint Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract
    Hiroyuki Tsujino
    Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Ultrasound Med Biol 30:1441-6. 2004
    ..3 mL, y = 1. 05 x -2. 5, r = 0. 94, p < 0. 01). The new method allowed accurate SV estimations without any geometric assumptions of the spatial velocity distributions...
  40. ncbi request reprint Assessment of left ventricular torsional deformation by Doppler tissue imaging: validation study with tagged magnetic resonance imaging
    Yuichi Notomi
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 111:1141-7. 2005
    ..The present study tested the accuracy of a novel method that uses Doppler tissue imaging (DTI) for quantifying LV torsion in humans with tagged magnetic resonance imaging (MRI) as a reference...
  41. ncbi request reprint Speckle tracking echocardiography in the assessment of mouse models of cardiac dysfunction
    Yu Peng
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Am J Physiol Heart Circ Physiol 297:H811-20. 2009
    ..45 and r = -0.44, respectively, and P = 0.006 for both). STE correctly identifies LV dysfunction and histological changes in mice and can be used for the serial assessment of cardiac remodeling in murine models...
  42. ncbi request reprint Automated mitral annular tracking: a novel method for evaluating mitral annular motion using two-dimensional echocardiography
    Yoko Eto
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 18:306-12. 2005
    ..The novel automated mitral annular tracking method is clinically feasible and has potential capability to quantify the comprehensive mitral annular motion for evaluating LV function in a clinical setting...
  43. ncbi request reprint Giant flow reversal in pulmonary venous flow as a possible mechanism for asynchronous pacing-induced heart failure
    Tomotsugu Tabata
    Section of Cardiovascular Imaging, Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Soc Echocardiogr 18:722-8. 2005
    ..We evaluated the impact of asynchronous rapid ventricular pacing on LA hemodynamics in this model...
  44. ncbi request reprint Scaling of diastolic intraventricular pressure gradients is related to filling time duration
    Zoran B Popovic
    Cardiovascular Imaging Center, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 291:H762-9. 2006
    ..65, P < 0.001). We conclude that IVPD decrease, while IVPG increase with decreasing animal size. High IVPG in small mammals may be an adaptive mechanism to short filling times...
  45. ncbi request reprint Influence of structural geometry on the severity of bicuspid aortic stenosis
    Kathryn E Richards
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Physiol Heart Circ Physiol 287:H1410-6. 2004
    ..Thus, for the same anatomic orifice area, functional severity is greater in bicuspid than in degenerative tricuspid AS...
  46. doi request reprint Dynamic change of mitral annular geometry and motion in ischemic mitral regurgitation assessed by a computerized 3D echo method
    Masao Daimon
    Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Echocardiography 27:1069-77. 2010
    ....
  47. ncbi request reprint Echocardiographic insights into atrial and ventricular mechanisms of functional tricuspid regurgitation
    Shota Fukuda
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:1208-14. 2006
    ..The purpose of this study was therefore to investigate the relationships between TV annular dilatation and leaflet tethering with the severity of functional TR and to investigate factors that influence these TV deformations...
  48. ncbi request reprint Influence of different implantation techniques on long-term survival after orthotopic heart transplantation: an echocardiographic study
    Jing Ping Sun
    Department of Cardiology, The Cleveland Clinic Foundation, Norcross, GA 30308, USA
    J Heart Lung Transplant 26:1243-8. 2007
    ..The aim of this study was to compare OHT outcomes when using the bicaval technique vs the biatrial technique...
  49. ncbi request reprint Relation of left atrial dysfunction to pulmonary artery hypertension in patients with aortic stenosis and left ventricular systolic dysfunction
    Roberto M Saraiva
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 106:409-16. 2010
    ..LA function recovered after AV replacement. Additional studies are warranted to determine the prognostic significance of LA function in this setting...
  50. ncbi request reprint Relationship of diastolic intraventricular pressure gradients and aerobic capacity in patients with diastolic heart failure
    Aleksandr Rovner
    Department of Cardiology, Barnes Jewish Hospital, St Louis, Missouri, USA
    Am J Physiol Heart Circ Physiol 289:H2081-8. 2005
    ..Myocardial relaxation is an important determinant of exercise aerobic capacity. In heart failure patients, impaired myocardial relaxation is associated with reduced diastolic suction force during exercise...
  51. ncbi request reprint Importance of mitral valve repair associated with left ventricular reconstruction for patients with ischemic cardiomyopathy: a real-time three-dimensional echocardiographic study
    Jian Xin Qin
    Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Circulation 108:II241-6. 2003
    ..This study was designed to evaluate the impact of mitral valve (MV) repair associated with LV reconstruction on LV function 1-year after surgery in ICM patients assessed by real-time 3-dimensional echocardiography (3DE)...
  52. ncbi request reprint Planimetric assessment of anatomic valve area overestimates effective orifice area in bicuspid aortic stenosis
    Erwan Donal
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 18:1392-8. 2005
    ..Not uncommonly, however, anatomic valve area (AVAA) obtained by planimetry overestimates continuity-derived effective valve area (AVAE) in bicuspid AS...
  53. doi request reprint Effect of age, gender, and left ventricular diastolic function on left atrial volume index in adults without known cardiovascular disease or risk factors
    Wael Aljaroudi
    Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 111:1517-22. 2013
    ..There was no variation, however, by gender, age, or grade I DD, although subjects with long-standing grade I DD and/or high filling pressures were likely underrepresented...
  54. doi request reprint Impact of mitral regurgitation on reverse remodeling and outcome in patients undergoing cardiac resynchronization therapy
    David Verhaert
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Circ Cardiovasc Imaging 5:21-6. 2012
    ..We sought to evaluate the relationship between serial measurements of functional MR and reverse remodeling and outcomes in patients undergoing CRT...
  55. ncbi request reprint Dynamic change in mitral annular area and motion during percutaneous mitral annuloplasty for ischemic mitral regurgitation: preliminary animal study with real-time 3-dimensional echocardiography
    Masao Daimon
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 20:381-8. 2007
    ..3 +/- 1.1-7.0 +/- 1.9 mm, P = .13). This 3D echocardiographic method noninvasively enabled dynamic study of mitral annular geometry and motion with quantitative analysis of the impact of PTMA...
  56. ncbi request reprint Geometric differences of the mitral apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation: real-time three-dimensional echocardiography study
    Jun Kwan
    Cardiovascular Imaging Center, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 107:1135-40. 2003
    ....
  57. pmc Differences in left ventricular long-axis function from mice to humans follow allometric scaling to ventricular size
    Zoran B Popovic
    Department of Cardiology, Desk F 15, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Physiol 568:255-65. 2005
    ..019 (P<0.0001 versus 0). We conclude that MA velocity, displacement, and long-to-short axis displacement ratio scale allometrically to heart size. This reduces the relative long-axis contribution to heart function in small mammals...
  58. ncbi request reprint Comparison of left ventricular diastolic function in obstructive hypertrophic cardiomyopathy in patients undergoing percutaneous septal alcohol ablation versus surgical myotomy/myectomy
    Marta Sitges
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 91:817-21. 2003
    ..Thus, diastolic function indexes obtained by echocardiography changed after septal reduction interventions in patients with obstructive HC; this change was similar to that after surgical myectomy and ASR...
  59. ncbi request reprint Determinant of left atrial dilation in patients with hypertrophic cardiomyopathy: a real-time 3-dimensional echocardiographic study
    Fabrice Bauer
    Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Soc Echocardiogr 17:968-75. 2004
    ....
  60. ncbi request reprint Echocardiographic assessment of regional ventricular function after device-based change of left ventricular shape
    Zoran B Popovic
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA
    J Am Soc Echocardiogr 17:411-7. 2004
    ..02 and P =.01, respectively). Structural modeling confirmed that Myosplint implantation increases regional stress heterogeneity and curvature heterogeneity. LV cross-sectional shape markedly affects regional LV performance...
  61. doi request reprint Incremental prognostic value of assessing left ventricular myocardial mechanics in patients with chronic systolic heart failure
    Hirohiko Motoki
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA
    J Am Coll Cardiol 60:2074-81. 2012
    ..This study sought to examine the ability of left ventricular (LV) global longitudinal strain (GLS) to assess disease severity in patients with chronic systolic heart failure (HF)...
  62. ncbi request reprint Intraventricular pressure gradients in left ventricular aneurysms determined by color M-mode Doppler method: an animal study
    Junko Asada-Kamiguchi
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Soc Echocardiogr 19:1112-8. 2006
    ..The aim of this study was to validate the accuracy of CMM echocardiography for assessing the existence and size of LVA and to determine the intraventricular pressure gradient in LVA...
  63. doi request reprint Usefulness of left ventricular shape to predict the early recovery of left ventricular function after isolated aortic valve replacement for aortic valve stenosis
    Yoshiki Matsumura
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA
    Am J Cardiol 102:1530-4. 2008
    ..57 and 68% and 91% for end-systolic sphericity <0.47, respectively. In conclusion, LV spherical shape and dilatation predicted poor LV functional recovery after isolated AVR in severe AS...
  64. ncbi request reprint Echocardiographic predictors of successful versus unsuccessful mitral valve repair in ischemic mitral regurgitation
    Vorachai Kongsaerepong
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Cardiol 98:504-8. 2006
    ..These echocardiographic measurements should be used to guide the cardiologist and cardiac surgeon in the choice of MV repair versus replacement in patients with ischemic MR...
  65. doi request reprint Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: difference between functional mitral regurgitation and prolapse regurgitation
    Yoshiki Matsumura
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 155:231-8. 2008
    ..We investigated the 3-dimensional (3D) geometry of PISA of functional MR as opposed to that of MR due to mitral valve prolapse (MVP) by real-time 3D echocardiography with color Doppler capability...
  66. ncbi request reprint Enhanced ventricular untwisting during exercise: a mechanistic manifestation of elastic recoil described by Doppler tissue imaging
    Yuichi Notomi
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Circulation 113:2524-33. 2006
    ..Doppler tissue imaging (DTI) can detect myocardial motion, including torsion, whereas color M-mode Doppler (CMM) can quantify LV intraventricular pressure gradients (IVPGs)...
  67. ncbi request reprint Off-pump mitral valve repair using the Coapsys device: a pilot study in a pacing-induced mitral regurgitation model
    Kiyotaka Fukamachi
    Department of Biomedical Engineering, Lerner Research Institute, Cleveland, Ohio, USA
    Ann Thorac Surg 77:688-92; discussion 692-3. 2004
    ..The purpose of this study was to evaluate the ability of the Myocor Coapsys device to restore leaflet apposition and valve competency off-pump in a canine model of functional mitral regurgitation (MR)...
  68. ncbi request reprint Mitral annular motion as a surrogate for left ventricular ejection fraction: real-time three-dimensional echocardiography and magnetic resonance imaging studies
    Jian Xin Qin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Eur J Echocardiogr 5:407-15. 2004
    ..To validate the accuracy of mitral annular motion assessed by real-time three-dimensional echocardiography (RT3DE) as a surrogate for determination of the left ventricular function in comparison with magnetic resonance imaging (MRI)...
  69. ncbi request reprint Alterations of regional myocardial function in a swine model of myocardial infarction assessed by echocardiographic 2-dimensional strain imaging
    Jing Ping Sun
    The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Soc Echocardiogr 20:498-504. 2007
    ..This study attempted to apply radial strain, circumferential strain, radial displacement, and strain-based torsion analysis to differentiating the infarct, adjacent, and remote zones in a swine model of myocardial infarction...
  70. pmc How similar are the mice to men? Between-species comparison of left ventricular mechanics using strain imaging
    Kenya Kusunose
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 7:e40061. 2012
    ..We used 2-D speckle tracking strain imaging to determine whether LV myocardial strains and strain rates scale to heart size...
  71. ncbi request reprint Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness
    Zoran B Popovic
    Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Physiol Heart Circ Physiol 290:H1454-9. 2006
    ..The ability to regulate IVPGs during changes in preload is impaired with aging. Preserving ventricular compliance during aging by lifelong exercise training does not prevent this impairment...
  72. ncbi request reprint Ischemic and viable myocardium in patients with non-Q-wave or Q-wave myocardial infarction and left ventricular dysfunction: a clinical study using positron emission tomography, echocardiography, and electrocardiography
    Hua Yang
    Department of Cardiology, Cleveland, Ohio, USA
    J Am Coll Cardiol 43:592-8. 2004
    ..We investigated whether patients with non-Q-wave myocardial infarction (NQMI) have more ischemic viable myocardium (IVM) than patients with Q-wave myocardial infarction (QMI)...
  73. ncbi request reprint Evaluation of left ventricular outflow tract area after septal reduction in obstructive hypertrophic cardiomyopathy: a real-time 3-dimensional echocardiographic study
    Marta Sitges
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am Heart J 150:852-8. 2005
    ..We aimed to analyze the change in LVOT area after septal reduction interventions in patients with obstructive HC using RT3DE...
  74. ncbi request reprint Preload-adjusted right ventricular maximal power: concept and validation
    Soren Schenk
    Dept of Biomedical Engineering ND20, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 287:H1632-40. 2004
    ..Thus preload adjustment of PWR(mx) should consider a linear PWR(mx) versus EDV relationship with distinct V(0PWR). PAMP(V0PWR) is a preload-independent estimate of RV contractility that may eventually be determined noninvasively...
  75. ncbi request reprint Non-invasive evaluation of orthotopic heart transplant rejection by echocardiography
    Jing Ping Sun
    Cardiovascular Imaging Center and Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Heart Lung Transplant 24:160-5. 2005
    ..The purpose of this study was to identify demographic and echocardiographic factors associated with transplant rejection and develop a predictive model, which may reduce the number of cardiac biopsies...
  76. ncbi request reprint Coupled pacing improves cardiac efficiency during acute atrial fibrillation with or without cardiac dysfunction
    Hirotsugu Yamada
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 287:H2016-22. 2004
    ..Thus this pacing therapy may be a viable therapy for patients with concurrent atrial fibrillation and heart failure...
  77. ncbi request reprint Usefulness of intracardiac Doppler assessment of left atrial function immediately post-pulmonary vein antrum isolation to predict short-term recurrence of atrial fibrillation
    Atul Verma
    Department of Cardiology, Section of Cardiac Pacing and Electrophysiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 94:951-4. 2004
    ....
  78. doi request reprint Left atrial function assessed by real-time 3-dimensional echocardiography is related to right ventricular systolic pressure in chronic mitral regurgitation
    Roberto M Saraiva
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA
    Am Heart J 158:309-16. 2009
    ..Left atrial (LA) volume is a prognostic index in chronic mitral regurgitation (MR). However, little is known about LA function in this setting. We hypothesized that LA dysfunction is related to pulmonary hypertension in chronic MR...
  79. pmc Usefulness of plasma galectin-3 levels in systolic heart failure to predict renal insufficiency and survival
    W H Wilson Tang
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Ohio, USA
    Am J Cardiol 108:385-90. 2011
    ..However, we did not observe a relation between galectin-3 and echocardiographic or hemodynamic indexes...
  80. ncbi request reprint Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
    Jing Ping Sun
    Department of Cardiovascular Imaging, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44196, USA
    J Am Soc Echocardiogr 17:132-8. 2004
    ..Like pulsed Doppler mitral inflow velocity, tissue velocity and strain rate show age-related changes...
  81. ncbi request reprint Relation of hemoglobin A1c to left ventricular relaxation in patients with type 1 diabetes mellitus and without overt heart disease
    Mehdi H Shishehbor
    Department of Internal Medicine, Cardiovascular Imaging Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Am J Cardiol 91:1514-7, A9. 2003
  82. ncbi request reprint Diastolic alterations in infants exposed to intrauterine cocaine: a follow-up study by color kinesis
    Sudhir Ken Mehta
    Fairview Hospital and MetroHealth Medical Center, Cleveland, Ohio 44111, USA
    J Am Soc Echocardiogr 15:1361-6. 2002
    ..It is unknown whether these abnormalities are transient because of short-term effects or persist in older infants, possibly reflecting a teratogenic effect of cocaine...
  83. doi request reprint Role of the CHADS2 score in the evaluation of thromboembolic risk in patients with atrial fibrillation undergoing transesophageal echocardiography before pulmonary vein isolation
    Sarinya Puwanant
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 54:2032-9. 2009
    ....
  84. ncbi request reprint Slow rate during AF improves ventricular performance by reducing sensitivity to cycle length irregularity
    Zoran B Popovic
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
    Am J Physiol Heart Circ Physiol 283:H2706-13. 2002
    ..We conclude that prolongation of the VCL during AF reduces the sensitivity of the LV performance parameters to irregularity...
  85. ncbi request reprint In vivo short-term Doppler hemodynamic profiles of 189 Carpentier-Edwards Perimount pericardial bioprosthetic valves in the mitral position
    Sibyll Goetze
    Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Soc Echocardiogr 17:981-7. 2004
    ..5% of all valves. This is the largest series establishing the favorable hemodynamic behavior of the different sizes of a new Perimount mitral valve, and the reported data could serve as a reference...
  86. ncbi request reprint Survival after aortic valve replacement for severe aortic stenosis with low transvalvular gradients and severe left ventricular dysfunction
    Jeremy J Pereira
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 39:1356-63. 2002
    ..We sought to assess whether aortic valve replacement (AVR) among patients with severe aortic stenosis (AS), severe left ventricular (LV) dysfunction and a low transvalvular gradient (TVG) is associated with improved survival...
  87. ncbi request reprint Comparative value of single-beat load-independent contractility indices in dilated cardiomyopathy and mitral regurgitation
    Zoran B Popovic
    Cardiovascular Imaging Center, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Soc Echocardiogr 16:703-11. 2003
    ..We sought to compare single-beat estimates of contractility indices...
  88. ncbi request reprint Induction and maintenance of an experimental model of severe cardiomyopathy with a novel protocol of rapid ventricular pacing
    Masami Takagaki
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Thorac Cardiovasc Surg 123:544-9. 2002
    ..The purpose of this study was to evaluate a unique new model of severe heart failure developed by means of a novel protocol of rapid ventricular pacing...
  89. ncbi request reprint Doppler-derived myocardial systolic strain rate is a strong index of left ventricular contractility
    Neil L Greenberg
    Cardiovascular Imaging Center, Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio OH 44195, USA
    Circulation 105:99-105. 2002
    ....
  90. ncbi request reprint Registration of real-time 3-D ultrasound images of the heart for novel 3-D stress echocardiography
    Raj Shekhar
    Department of Biomedical Engineering ND20, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    IEEE Trans Med Imaging 23:1141-9. 2004
    ..The 3-D spatial registration is mutual information-based. Image registration used in conjunction with 3-D stress echocardiography can potentially improve the diagnostic accuracy of stress testing...
  91. ncbi request reprint Contrast and harmonic imaging improves accuracy and efficiency of novice readers for dobutamine stress echocardiography
    Irmien Vlassak
    Cleveland Clinic Foundation, Department of Cardiology, Cleveland, Ohio 44195, USA
    Echocardiography 19:483-8. 2002
    ..This study was performed to evaluate whether these new imaging modalities would improve endocardial visualization and enhance accuracy and efficiency of the inexperienced reader interpreting dobutamine stress echocardiography...
  92. ncbi request reprint Hemodynamic stability during 17 years of the Carpentier-Edwards aortic pericardial bioprosthesis
    Michael K Banbury
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 73:1460-5. 2002
    ..To anticipate the fate of this bioprosthesis, we examined its hemodynamic performance up to 17 years using echocardiographic studies in a Premarket Approval cohort...
  93. ncbi request reprint Comparison of ability to identify left atrial thrombus by three-dimensional tomography versus transesophageal echocardiography in patients with atrial fibrillation
    Wael A Jaber
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 93:486-9. 2004
    ..Our data suggest that computed tomography is a potential alternative for assessing the anatomy of the left atrial appendage and for detecting thrombi...
  94. ncbi request reprint Plasma B-type natriuretic peptide levels in systolic heart failure: importance of left ventricular diastolic function and right ventricular systolic function
    Richard W Troughton
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 43:416-22. 2004
    ....
  95. ncbi request reprint Quantitative analysis of aortic regurgitation: real-time 3-dimensional and 2-dimensional color Doppler echocardiographic method--a clinical and a chronic animal study
    Takahiro Shiota
    Department of Cardiology F 15, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 15:966-71. 2002
    ..For evaluating patients with aortic regurgitation (AR), regurgitant volumes, left ventricular (LV) stroke volumes (SV), and absolute LV volumes are valuable indices...
  96. ncbi request reprint Tissue synchronization imaging and optimal left ventricular pacing site in cardiac resynchronization therapy
    Ross T Murphy
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Cardiol 97:1615-21. 2006
    ..In conclusion, pacing at the site of maximal mechanical delay was associated with reverse remodeling. Individually tailored LV lead positioning should be considered before CRT...
  97. ncbi request reprint A new automated method for the quantification of mitral regurgitant volume and dynamic regurgitant orifice area based on a normalized centerline velocity distribution using color M-mode and continuous wave Doppler imaging
    Dimitri Deserranno
    Cleveland Clinic Foundation, Department of Cardiology, Cardiovascular Imaging, 9500 Euclid Ave, Desk F15, Cleveland, OH 44195, USA
    J Biomech Eng 125:62-9. 2003
    ..The model output (y) and reference (x) values were in close agreement (y = 0.95x + 0.38, r = 0.96, error = 1.68 +/- 7.54% for the orifice diameter and y = 1.18x - 4.72, r = 0.93, error = 6.48 +/- 16.81% for the regurgitant volume)...
  98. doi request reprint Impact of left ventricular size on tissue Doppler and longitudinal strain by speckle tracking for assessing wall motion and mechanical dyssynchrony in candidates for cardiac resynchronization therapy
    Pascal Lim
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Am Soc Echocardiogr 22:695-701. 2009
    ..Myocardial dysfunction and left ventricular (LV) geometry deformation may reduce the accuracy of tissue Doppler imaging (TDI) in assessing myocardial contractility...
  99. ncbi request reprint Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model
    Kai Wang
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Arterioscler Thromb Vasc Biol 23:357-62. 2003
    ..We assessed the influence of a selective P2Y(12)-receptor antagonist (AR-C69931MX), in conjunction with thrombolytic therapy, on the prevention of platelet aggregation and thrombus formation...
  100. ncbi request reprint Prevalence of left ventricular diastolic dysfunction by Doppler echocardiography: clinical application of the Canadian consensus guidelines
    Hirotsugu Yamada
    Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Soc Echocardiogr 15:1238-44. 2002
    ..Standard guidelines of Doppler echocardiographic parameters allow semiquantitation of diastolic function and can be applied to studying large number of patients in a large clinical practice...
  101. doi request reprint Mortality rate in patients with diastolic dysfunction and normal systolic function
    Carmel M Halley
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Arch Intern Med 171:1082-7. 2011
    ..Diastolic dysfunction (DD) is known to be associated with increased mortality rate in the presence of impaired systolic function. However, few prognostic data exist regarding the effect of DD in patients with normal systolic function...