Research Topics
| T StevensSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Publications
Lipidomic profiling of serum and pancreatic fluid in chronic pancreatitisTyler Stevens
Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA
Pancreas 41:518-22. 2012..The aim was to determine whether oxidized fatty acid (OxFA) levels in serum and/or pancreatic fluid are elevated in CP...
Endoscopic ultrasonography to evaluate pancreatitisSiwar Albashir
Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 79:202-6. 2012..However, further studies are needed to define its diagnostic role in patients with recurrent acute pancreatitis and minimal-change chronic pancreatitis...
Combined endoscopic ultrasound and secretin endoscopic pancreatic function test in patients evaluated for chronic pancreatitisTyler Stevens
Digestive Disease Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, A31, Cleveland, OH 44195, USA
Dig Dis Sci 55:2681-7. 2010..Endoscopic ultrasound and endoscopic secretin pancreatic function test may be combined in a single endoscopic session (EUS/ePFT) to diagnose chronic pancreatitis (CP)...
Acute pancreatitis: problems in adherence to guidelinesTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Cleve Clin J Med 76:697-704. 2009..Although evidence-based guidelines on managing acute pancreatitis are available, many physicians are not following them. The authors identify and discuss several problems in adherence to guidelines on testing, imaging, and treatment...
Prospective comparison of radial and linear endoscopic ultrasound for diagnosis of chronic pancreatitisT Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Endoscopy 41:836-41. 2009..The aim of this study was to compare radial and linear EUS for the diagnosis of chronic pancreatitis using the secretin-stimulated endoscopic pancreatic function test (ePFT) as the reference standard...
Endoscopic ultrasound for the diagnosis of chronic pancreatitisTyler Stevens
Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland Ohio 44195, USA
World J Gastroenterol 16:2841-50. 2010....
Evaluation of duct-cell and acinar-cell function and endosonographic abnormalities in patients with suspected chronic pancreatitisTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Clin Gastroenterol Hepatol 7:114-9. 2009..Direct pancreatic function tests (PFTs) detect mild exocrine insufficiency associated with early fibrosis. The primary aim of this study was to compare EUS structural criteria with duct-cell and acinar-cell function...
Multicenter comparison of the interobserver agreement of standard EUS scoring and Rosemont classification scoring for diagnosis of chronic pancreatitisTyler Stevens
Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Gastrointest Endosc 71:519-26. 2010..EUS has less than optimal interobserver agreement for the diagnosis of chronic pancreatitis. The newly developed Rosemont consensus scoring system includes weighted criteria and stricter definitions for individual features...
Comparison of endoscopic ultrasound and endoscopic retrograde pancreatography for the prediction of pancreatic exocrine insufficiencyTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, 9500 Euclid Ave, Desk A31, Cleveland, OH 44195, USA
Dig Dis Sci 53:1146-51. 2008..4 and 4.9, respectively) and severe structural changes (OR 12 and 24, respectively). We consider EUS to have a diagnostic accuracy for the structural diagnosis of early- and late-stage chronic pancreatitis similar to that of ERP...
Update on the role of endoscopic ultrasound in chronic pancreatitisTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic, 9500 Euclid Avenue, Desk A31, Cleveland, OH 44195, USA
Curr Gastroenterol Rep 13:117-22. 2011..EUS-directed celiac plexus blockade and ductal access techniques have expanded the therapeutic armamentarium for pain management in CP...
Azathioprine formulation optimizes metabolite profile in inflammatory bowel diseaseT Stevens
Department of Gastroenterology and Hepatology, Center for Inflammatory Bowel Disease, Cleveland Clinic Foundation, OH 44195, USA
Aliment Pharmacol Ther 20:601-6. 2004..Recent studies have suggested that mercaptopurine metabolism is influenced by drug formulation (mercaptopurine vs. azathioprine) and concomitant use of 5-aminosalicylic acid medications...
Analysis of pancreatic elastase-1 concentrations in duodenal aspirates from healthy subjects and patients with chronic pancreatitisTyler Stevens
The Pancreas Clinic, Section of Endoscopy, Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44118, USA
Dig Dis Sci 49:1405-11. 2004..4) Secretin-stimulated endoscopic function testing with measurement of bicarbonate and PE-1 may provide a simultaneous assessment of both ductal cell and acinar cell function...
A randomized crossover study of secretin-stimulated endoscopic and dreiling tube pancreatic function test methods in healthy subjectsTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Gastroenterol 101:351-5. 2006..There is an excellent correlation in peak [HCO3-] and high level of diagnostic agreement between the tests...
The efficiency of endoscopic pancreatic function testing is optimized using duodenal aspirates at 30 and 45 minutes after intravenous secretinTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Gastroenterol 102:297-301. 2007..The endoscopic secretin test (ePFT) takes an hour to perform, limiting its practicality for routine use. We sought to determine which timed endoscopic collections best predict the peak bicarbonate concentration from full hour-long test...
Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel diseaseJean Paul Achkar
Center for Inflammatory Bowel Disease, Departments of Gastroenterology and Biostatistics, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Inflamm Bowel Dis 10:339-45. 2004..The purpose of this study was to assess the relation between clinical response, 6-mercaptopurine metabolite levels, relative leukopenia, and drug dose...
Extracorporeal shock wave lithotripsy for prevention of recurrent pancreatitis caused by obstructive pancreatic stonesMansour A Parsi
Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH 44195, USA
Pancreas 39:153-5. 2010..However, its effect on prevention of recurrent pancreatitis in this group of patients has not been studied...
Endoscopic ultrasound, secretin endoscopic pancreatic function test, and histology: correlation in chronic pancreatitisSiwar Albashir
Internal Medicine Residency, Cleveland Clinic, Cleveland, Ohio, USA
Am J Gastroenterol 105:2498-503. 2010..The aims were to assess correlations of EUS score and endoscopic pancreatic function test (ePFT) results with the degree of histological fibrosis, as well as the sensitivity of each method for detecting fibrosis...
Endoscopic therapy of recurrent acute pancreatitisMansour A Parsi
Department of Gastroenterology and Hepatology, A31, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 76:225-33. 2009..In this article, the authors review the specific situations in which endoscopic therapy might be useful in patients with acute recurrent pancreatitis...
Findings on endoscopic retrograde cholangiopancreatography and pancreatic function test in suspected chronic pancreatitis and negative cross-sectional imagingMansour A Parsi
Center for Endoscopy and Pancreatobiliary Disorders, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Clin Gastroenterol Hepatol 6:1432-6. 2008....
A prospective crossover study comparing secretin-stimulated endoscopic and Dreiling tube pancreatic function testing in patients evaluated for chronic pancreatitisTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Gastrointest Endosc 67:458-66. 2008..Direct pancreatic function tests (PFT) are conventionally performed with use of double-lumen "Dreiling" collection tubes. We have developed an endoscopic collection method (ePFT) that eases the performance of these tests...
Autoimmune pancreatitis: a mimic of pancreatic cancerRyan Law
Department of General Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Cleve Clin J Med 76:607-15. 2009..The diagnosis of autoimmune pancreatitis is challenging to make. However, accurate and timely diagnosis may preempt the misdiagnosis of cancer and decrease the number of unnecessary pancreatic resections...
Capnographic monitoring of respiratory activity improves safety of sedation for endoscopic cholangiopancreatography and ultrasonographyMohammed A Qadeer
Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Gastroenterology 136:1568-76; quiz 1819-20. 2009..We sought to determine whether intervention, based on a microstream capnography-based ventilation monitoring system that has been shown to function as an early warning system for hypoxemia, would decrease hypoxemia during endoscopy...
Bispectral index monitoring of conscious sedation with the combination of meperidine and midazolam during endoscopyMohammed A Qadeer
Section of Therapeutic Endoscopy, Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Clin Gastroenterol Hepatol 6:102-8. 2008..Thus, we performed a prospective observational study to assess its ability for detecting deep sedation during endoscopy...
Electrolyte composition of endoscopically collected duodenal drainage fluid after synthetic porcine secretin stimulation in healthy subjectsTyler Stevens
The Pancreas Clinic, Section of Endoscopy, Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, 9500 Euclid Avenue A30, Cleveland, OH 44118, USA
Gastrointest Endosc 60:351-5. 2004..CONCLUSIONS: Endoscopic collection of pancreatic fluid reproduces the anion-cation secretory curve described by prior studies of pancreatic secretory physiology based on traditional collection methods...
Cigarette smoking is independently associated with chronic pancreatitisRyan Law
Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Pancreatology 10:54-9. 2010..Past studies have included mostly patients with alcohol-related and severe CP. Our aim was to assess the relationship of smoking and CP adjusting for alcohol and other clinical risk factors...
Pathogenesis of chronic pancreatitis: an evidence-based review of past theories and recent developmentsTyler Stevens
The Pancreas Clinic, Section of Endoscopy and Pancreaticobiliary Disease, Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44118, USA
Am J Gastroenterol 99:2256-70. 2004..Moreover, we will discuss plausible pathogenic sequences applied to each of the known etiologies...
Pancreatic cyst aspiration analysis for cystic neoplasms: mucin or carcinoembryonic antigen--which is better?Gareth Morris-Stiff
Department of Hepato pancreato biliary Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Surgery 148:638-44; discussion 644-5. 2010..We sought to report the results of this ongoing protocol and determine the relative importance of cyst fluid mucin and CEA for the diagnostic process...
Eosinophilic pancreatitis presenting as a pancreatic mass with obstructive jaundiceTyler Stevens
Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, OH 44195, USA
Gastrointest Endosc 63:525-7. 2006
