Research Topics
Genomes and GenesSpecies | A E SipersteinSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Laparoscopic posterior adrenalectomy: technical considerationsA E Siperstein
Department of General Surgery, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
Arch Surg 135:967-71. 2000..We hypothesized that LPA is a safe and efficacious procedure that could best serve certain patients with adrenal tumors...
Predicting the success of limited exploration for primary hyperparathyroidism using ultrasound, sestamibi, and intraoperative parathyroid hormone: analysis of 1158 casesAllan Siperstein
Endocrine and Metabolism Institute, Section of Endocrine Surgery, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Ann Surg 248:420-8. 2008..The aim of this study was to determine the success of limited neck exploration (LE) for primary hyperparathyroidism (1 degrees HPT)...
Survival after radiofrequency ablation of colorectal liver metastases: 10-year experienceAllan E Siperstein
Department of General Surgery, The Cleveland Clinic, Cleveland, OH, USA
Ann Surg 246:559-65; discussion 565-7. 2007..To assess factors affecting long-term survival of patients undergoing radiofrequency ablation (RFA) of colorectal hepatic metastases, with attention to evolving chemotherapy regimens...
The use of the harmonic scalpel vs conventional knot tying for vessel ligation in thyroid surgeryAllan E Siperstein
Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Ave, Desk A80, Cleveland, OH 44195, USA
Arch Surg 137:137-42. 2002..We hypothesized that the use of the harmonic scalpel could lead to a significant reduction in operative time as compared with knot tying in thyroid surgery...
A critical analysis of intraoperative time utilization in laparoscopic cholecystectomyE Berber
Department of General Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 15:161-5. 2001..In patients with choledocholithiasis, stone extraction was responsible for longer operating times. This study should serve as a basis for future studies focusing on time utilization in laparoscopic surgery...
Thyroid-stimulating hormone receptor messenger ribonucleic acid measurement in blood as a marker for circulating thyroid cancer cells and its role in the preoperative diagnosis of thyroid cancerSu Ynn Chia
Department of Endocrinology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
J Clin Endocrinol Metab 92:468-75. 2007..Thyroid cancer cells express TSH receptor (TSHR) mRNA, and its measurement in the circulation may be useful in the diagnosis/management of differentiated thyroid cancer (DTC)...
Prospective evaluation of sestamibi scan, ultrasonography, and rapid PTH to predict the success of limited exploration for sporadic primary hyperparathyroidismAllan Siperstein
Department of General Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Surgery 136:872-80. 2004..A bilateral approach offers the best opportunity for the long-term cure of primary hyperparathyroidism...
Intraoperative thermal regulation in patients undergoing laparoscopic vs open surgical proceduresE Berber
Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Surg Endosc 15:281-5. 2001..7 degrees C, p > 0.05). CONCLUSION: This study demonstrates that patients who undergo laparoscopic and open procedures of similar duration under endotracheal general anesthesia have similar profiles in terms of perioperative hypothermia...
Laparoscopic radiofrequency ablation of hepatic tumors: prospective clinical evaluation of ablation size comparing two treatment algorithmsE Berber
Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 18:390-6. 2004..Algorithm 2 demonstrates that creating an initial small core of ablation with rapid coagulation of the center of the lesion allows for equivalent, if not larger, final volumes to be performed in less time...
Perioperative outcome after laparoscopic radiofrequency ablation of liver tumors: an analysis of 521 casesE Berber
Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 21:613-8. 2007..Understanding the morbidity and laboratory changes after RFA is important for operative indications and perioperative management...
Understanding and optimizing laparoscopic videosystemsE Berber
Department of General Surgery/A80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 15:781-7. 2001..An insight into the future of laparoscopic video systems also is made, and practical tips for improving image quality and troubleshooting are given throughout the article...
Double adenomas revisited: nonuniform distribution favors enlarged superior parathyroids (fourth pouch disease)Mira Milas
Department of General Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue/A80, Cleveland, OH 44195, USA
Surgery 134:995-1003; discussion 1003-4. 2003..Since additional abnormal glands were detected by observation with technetium 99 metastable (Tc99m)-sestamibi imaging and IOPTH rarely aiding detection, unilateral neck exploration may predispose to persistent or recurrent HPT...
Use of the optical access trocar for safe and rapid entry in various laparoscopic proceduresA String
Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 15:570-3. 2001..Thanks to our favorable experience, the optical trocar method has become the standard technique for abdominal access in our laparoscopic practice since 1995...
Laparoscopic ultrasonographic appearance of the common bile duct mucosa: a predictor of choledocholithiasisE Berber
Department of General Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
J Ultrasound Med 20:15-9. 2001..This finding is evident in the majority of patients with common bile duct stones and also may be associated with recent passage of a stone into the duodenum...
Cryoablation, percutaneous alcohol injection, and radiofrequency ablation for treatment of neuroendocrine liver metastasesA E Siperstein
Department of General Surgery/A80, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
World J Surg 25:693-6. 2001..Radiofrequency thermal ablation is a relatively new modality that can be performed percutaneously or laparoscopically, and encouraging results have been obtained with it for treatment of neuroendocrine liver metastases...
Effectiveness of peripheral thyrotropin receptor mRNA in follow-up of differentiated thyroid cancerMira Milas
Department of General Surgery, Cleveland Clinic, OH 44195, USA
Ann Surg Oncol 16:473-80. 2009..As a novel adjunct, TSHR mRNA may enhance long-term management of TC patients...
Circulating thyrotropin receptor mRNA as a novel marker of thyroid cancer: clinical applications learned from 1758 samplesMira Milas
Department of Endocrine Surgery, Endocrinology and Metabolism Institute, Cleveland Clinic, Main Campus, Cleveland, OH 44195, USA
Ann Surg 252:643-51. 2010..This prospective validation study tests the ability of TSHR mRNA to diagnose DTC preoperatively and to detect cancer recurrence...
Thyrotropin receptor/thyroglobulin messenger ribonucleic acid in peripheral blood and fine-needle aspiration cytology: diagnostic synergy for detecting thyroid cancerKristin Wagner
Department of Clinical Pathology, L-30, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
J Clin Endocrinol Metab 90:1921-4. 2005....
Clinical utility of noncontrast computed tomography attenuation value (hounsfield units) to differentiate adrenal adenomas/hyperplasias from nonadenomas: Cleveland Clinic experienceAmir H Hamrahian
Department of Endocrinology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
J Clin Endocrinol Metab 90:871-7. 2005....
Local recurrence after laparoscopic radiofrequency ablation of liver tumors: an analysis of 1032 tumorsEren Berber
Center for Endocrine Surgery, Cleveland Clinic, 9500 Euclid Ave A80, Cleveland, OH 44195, USA
Ann Surg Oncol 15:2757-64. 2008..The best measure of the technical success of radiofrequency ablation (RFA) is local recurrence (LR). The aim of this prospective study is to identify factors that predict LR...
Ultrasonography for the endocrine surgeon: a valuable clinical tool that enhances diagnostic and therapeutic outcomesMira Milas
Department of General Surgery, Cleveland Clinic Foundation, OH 44195, USA
Surgery 138:1193-200; discussion 1200-1. 2005..We report our experience on the impact of surgeon-performed U/S in an endocrine surgery practice...
The utility of peripheral thyrotropin mRNA in the diagnosis of follicular neoplasms and surveillance of thyroid cancersMira Milas
Department of General Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Surgery 141:137-46; discussion 146. 2007..Thyroid cells in peripheral circulation express uniquely thyrotropin receptor (TSHR) mRNA, and their detection may aid thyroid cancer management...
Unrecognized adrenal insufficiency in patients undergoing laparoscopic adrenalectomyJamie Mitchell
Endocrinology and Metabolism Institute, Section of Endocrine Surgery A 80, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 23:248-54. 2009..m.) serum cortisol levels on postoperative day 1 (POD1) following unilateral adrenalectomy for nonfunctioning adrenal lesions to determine the incidence of unrecognized adrenal insufficiency (AI) in these patients...
The impact of office neck ultrasonography on reducing unnecessary thyroid surgery in patients undergoing parathyroidectomyMira Milas
The Department of General Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Thyroid 15:1055-9. 2005..We sought to define the incidence and optimal management strategies of thyroid disease in patients undergoing surgery for HPT...
Comparison of laparoscopic transabdominal lateral versus posterior retroperitoneal adrenalectomyEren Berber
Section of Endocrine Surgery, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Surgery 146:621-5; discussion 625-6. 2009..The aim of this study is to describe patient selection criteria for each approach with comparison of perioperative outcomes...
Detection of thyrotropin-receptor messenger ribonucleic acid (mRNA) and thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease: sensitive and specific markers for thyroid cancerPriya Chinnappa
Department of Endocrinology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Clin Endocrinol Metab 89:3705-9. 2004..Furthermore, the high specificity combined with their ability to predict thyroid cancer preoperatively suggests a potential role in detecting thyroid cancer in patients with thyroid nodules...
Robotic posterior retroperitoneal adrenalectomy: operative techniqueEren Berber
Division of Endocrine Surgery, Endocrinology and Metabolism Institute, 9500 Euclid Ave, F20, Cleveland, OH 44195, USA
Arch Surg 145:781-4. 2010..To describe a robotic technique for posterior retroperitoneal (PR) adrenalectomy...
Robotic transaxillary thyroidectomy: report of 2 cases and description of the techniqueEren Berber
Endocrinology and Metabolism Institute, Section of Endocrine Surgery, Cleveland, OH 44195, USA
Surg Laparosc Endosc Percutan Tech 20:e60-3. 2010..We found that robotic resection avoids a neck scar and offers quality 3-dimensional vision with dexterity similar to the human hand...
Laparoscopic radiofrequency thermal ablation of adrenal tumors: technical detailsEren Berber
Division of Endocrine Surgery, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Surg Laparosc Endosc Percutan Tech 20:58-62. 2010..The aim of this study is to describe patient selection criteria and the technique for laparoscopic adrenal RFA...
A critical analysis of intraoperative time utilization in laparoscopic adrenalectomyE Berber
Department of General Surgery/A80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 16:258-62. 2002..This study also suggests that efforts to improve operative efficiency are best directed at the dissection of the adrenal...
Avoidable reoperations for thyroid and parathyroid surgery: effect of hospital volumeJamie Mitchell
Endocrinology and Metabolism Institute, Section of Endocrine Surgery, The Cleveland Clinic, Cleveland, Ohio, USA
Surgery 144:899-906; discussion 906-7. 2008..Hospital volume for thyroid and parathyroid surgery inversely correlates with perioperative complications. This correlation has not been made regarding the need for reoperation...
Detection of circulating thyroid cancer cells in patients with thyroid microcarcinomasTomislav Novosel
Endocrine Surgery Department, Endocrinology and Metabolism Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Surgery 146:1081-9. 2009..The aim of this study was to determine detectability and clinical importance of TSHR mRNA in patients with microcarcinomas...
A simple device for measuring the resolution of videoscopic cameras and laparoscopes in the operating roomE Berber
Department of General Surgery/A80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Endosc 16:1111-3; discussion 1114. 2002..This information can be used as objective criteria to judge the image quality in laparoscopic video- systems...
Change in adrenal mass size as a predictor of a malignant tumorKevin M Pantalone
Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Endocr Pract 16:577-87. 2010..To assess the value of adrenal mass absolute growth, growth rate, and percentage growth rate on serial imaging for distinguishing benign from malignant adrenal masses...
Myoglobinuria after laparoscopic radiofrequency ablation of liver tumorsJohn Rodriguez
Division of Endocrine Surgery, Cleveland Clinic, Endocrinology and Metabolism Institute, Cleveland, OH, USA
J Gastrointest Surg 14:664-7. 2010..There are scant data in the literature about myoglobinuria after radiofrequency ablation (RFA) of liver tumors. The aim of this study is to analyze the incidence and identify the risk factors involved in this complication after RFA...
Pattern of carcinoembryonic antigen drop after laparoscopic radiofrequency ablation of liver metastasis from colorectal carcinomaMohammed Ghanamah
Department of General Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Cancer 107:149-53. 2006..Little is known, however, about the expected pattern of the CEA drop after RFA...
Laparoscopic radiofrequency ablation of liver tumors combined with colorectal proceduresEren Berber
Department of General Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Surg Laparosc Endosc Percutan Tech 14:186-90. 2004..These data support the concept that RFA may be safely used with concomitant colon resections to treat liver metastases that may be resectable but are associated with increased morbidity if resected synchronously...
Laparoscopic adrenalectomy: a cost analysis of three approachesHoussam Farres
Department of General Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Laparoendosc Adv Surg Tech A 14:23-6. 2004..Our data demonstrates no significant difference in operative cost between the respective techniques. Operative costs should not be a factor in choosing a laparoscopic approach for unilateral adrenal disease...
National trends in parathyroid surgery from 1998 to 2008: a decade of changeAndrew B Greene
Department of Endocrine Surgery, Endocrinology and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Am Coll Surg 209:332-43. 2009..The introduction of limited explorations (LE) for parathyroidectomy broadened the management possibilities for hyperparathyroidism. We sought to document this evolution of change in parathyroid surgery...
Appreciation of osteoporosis among men with hyperparathyroidismNaveen Ballem
Department of General Surgery, Endocrine Surgery Section, Cleveland Clinic, Cleveland, OH 44195, USA
Endocr Pract 14:820-31. 2008..To define the scope of bone disease among men referred for parathyroidectomy and to document bone density screening trends in this high-risk population...
Laparoscopic radiofrequency ablation of neuroendocrine liver metastasesEren Berber
Department of General Surgery/A80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Ohio 44195, USA
World J Surg 26:985-90. 2002..It is a useful modality in the management of these challenging group of patients...
Predictors of survival after radiofrequency thermal ablation of colorectal cancer metastases to the liver: a prospective studyEren Berber
Department of General Surgery and Hematology and Medical Oncology, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
J Clin Oncol 23:1358-64. 2005..Limited amounts of extrahepatic disease do not appear to affect survival adversely. RFA is a useful adjunct to chemotherapy in those patients with liver-predominant disease...
Factors contributing to negative parathyroid localization: an analysis of 1000 patientsEren Berber
Section of Endocrine Surgery, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, Ohio, USA
Surgery 144:74-9. 2008..This is a prospective study looking at the characteristics of the patient and the gland that determine the likelihood of an abnormal parathyroid to be detected by ultrasonography (US) and sestamibi scan (MIBI)...
Laparoscopic ultrasonography and biopsy of hepatic tumors in 310 patientsEren Berber
The Cleveland Clinic Foundation, Department of General Surgery, A80, 9500 Euclid Ave, Cleveland, OH 44195, USA
Am J Surg 187:213-8. 2004..CONCLUSIONS: The use of this minimally invasive technique avoids laparotomy in many patients undergoing staging of malignancy and also offers increased sensitivity for tumor detection compared with conventional imaging modalities...
Laparoscopic radiofrequency ablation of neuroendocrine liver metastases: a 10-year experience evaluating predictors of survivalPeter J Mazzaglia
Rhode Island Hospital, Providence, RI, USA
Surgery 142:10-9. 2007..This study analyzes our 10-year experience and determines characteristics predictive of survival...
Use of surgeon-performed office ultrasound and parathyroid fine needle aspiration for complex parathyroid localizationAntonia E Stephen
Department of Surgical Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
Surgery 138:1143-50; discussion 1150-1. 2005....
Results of laparoscopic adrenalectomy for suspected and unsuspected malignant adrenal neoplasmsElectron Kebebew
Department of Surgery, University of California, San Francisco 94121, USA
Arch Surg 137:948-51; discussion 952-3. 2002..Furthermore, preoperative fine-needle aspiration cytology for the evaluation of suspected malignant adrenal tumors is unreliable...
Complications of neck dissection for thyroid cancerW Keat Cheah
Department of Surgery, University of California, San Francisco/Mt. Zion Medical Center, 1600 Divisadero Street, 94143-1674, USA
World J Surg 26:1013-6. 2002..Therapeutic neck dissection or repeated neck dissection can be performed relatively safely in patients with thyroid cancer. Hypocalcemia occurs most frequently when neck dissection is combined with total thyroidectomy...
Radiofrequency ablation: the experts weigh inKenneth K Tanabe
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Cancer 100:641-50. 2004
Laparoscopic ultrasoundEren Berber
Surgical Resident Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surg Clin North Am 84:1061-84, vi. 2004..With the increasing availability of equipment, as well as the training of surgeons in this modality, laparoscopic ultrasound is quickly becoming an essential tool for the surgeon aiming to take laparoscopic surgery to new frontiers...
Laparoscopic adrenalectomy for pheochromocytomaW Keat Cheah
Department of Surgery, University of California San Francisco, Veterans Affairs Medical Center, 4150 Clement Street, 94121, USA
World J Surg 26:1048-51. 2002..Laparoscopic adrenalectomy is the preferred surgical approach for patients with pheochromocytoma because it is safe and efficacious...
Increased prevalence of breast cancer among patients with thyroid and parathyroid diseaseCarolyn N Garner
Department of General Surgery, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Surgery 142:806-13; discussion 813.e1-3. 2007..A breast cancer (BC) history was elicited more frequently than expected among thyroid operation patients, which prompted an investigation of risks for concurrent or subsequent nonendocrine malignancies...
Radiofrequency thermal ablation of metastatic neuroendocrine tumors in the liverPeter J Mazzaglia
Department of Surgery A 80, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, USA
Curr Treat Options Oncol 8:322-30. 2007..Utilizing a laparoscopic approach guided by intra-operative ultrasound, effective tumor ablation can be achieved with minimal morbidity and low rates of local tumor recurrence...
The coming of age of radiation-induced hyperparathyroidism: evolving patterns of thyroid and parathyroid disease after head and neck irradiationAntonia E Stephen
Department of Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Surgery 136:1143-53. 2004..Those patients who undergo surgical procedures should have close inspection of the parathyroid glands, with biopsy and excision when appropriate...
The changing presentation of hyperparathyroidism over 3 decadesPeter J Mazzaglia
Department of Surgery, A 80, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
Arch Surg 143:260-6. 2008..To analyze changes in the presentation of primary hyperparathyroidism over the last 3 decades...
