Arun D Singh

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint BIGH3 mutation spectrum in corneal dystrophies
    Francis L Munier
    Hopital Jules Gonin, Department of Ophthalmology, Lausanne, Switzerland
    Invest Ophthalmol Vis Sci 43:949-54. 2002
  2. doi request reprint Current appraisal of conjunctival melanocytic tumors: classification and treatment
    Hooman Harooni
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Future Oncol 7:435-46. 2011
  3. pmc Vascular tumors of the retina and choroid: diagnosis and treatment
    Mary E Turell
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
    Middle East Afr J Ophthalmol 17:191-200. 2010
  4. pmc Autoantibody against transient receptor potential M1 cation channels of retinal ON bipolar cells in paraneoplastic vitelliform retinopathy
    Yujuan Wang
    Section of Immunopathology, Laboratory of Immunology, National Eye Institute, National Institutes of Health, NIH NEI, Bethesda, MD 20892 1857, USA
    BMC Ophthalmol 12:56. 2012
  5. pmc Ocular phototherapy
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Eye (Lond) 27:190-8. 2013
  6. doi request reprint Management of radiation maculopathy
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ophthalmic Res 48:26-31. 2012
  7. doi request reprint Chromosome 3 status in uveal melanoma: a comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Invest Ophthalmol Vis Sci 53:3331-9. 2012
  8. ncbi request reprint Metastatic uveal melanoma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:143-50, ix. 2005
  9. ncbi request reprint Eccrine hidrocystoma of the eyelid
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, USA
    Eye (Lond) 19:77-9. 2005
  10. ncbi request reprint Sebaceous adenoma of the eyelid in Muir-Torre syndrome
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cliveland Clinic Foundation, OH 44195, USA
    Arch Ophthalmol 123:562-5. 2005

Detail Information

Publications96

  1. ncbi request reprint BIGH3 mutation spectrum in corneal dystrophies
    Francis L Munier
    Hopital Jules Gonin, Department of Ophthalmology, Lausanne, Switzerland
    Invest Ophthalmol Vis Sci 43:949-54. 2002
    ..To investigate the molecular pathology underlying BIGH3-related corneal dystrophies (CDs) and to further delineate genotype-phenotype specificity...
  2. doi request reprint Current appraisal of conjunctival melanocytic tumors: classification and treatment
    Hooman Harooni
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Future Oncol 7:435-46. 2011
    ..The management of primary acquired melanosis, nevi and conjunctival melanomas involves various modalities used either alone or concomitantly depending on the size and extent of the lesion...
  3. pmc Vascular tumors of the retina and choroid: diagnosis and treatment
    Mary E Turell
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
    Middle East Afr J Ophthalmol 17:191-200. 2010
    ....
  4. pmc Autoantibody against transient receptor potential M1 cation channels of retinal ON bipolar cells in paraneoplastic vitelliform retinopathy
    Yujuan Wang
    Section of Immunopathology, Laboratory of Immunology, National Eye Institute, National Institutes of Health, NIH NEI, Bethesda, MD 20892 1857, USA
    BMC Ophthalmol 12:56. 2012
    ..This is the first report of anti-transient receptor potential M1 antibody directly against human retinal bipolar dendritic tips in a melanoma patient with paraneoplastic vitelliform retinopathy...
  5. pmc Ocular phototherapy
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Eye (Lond) 27:190-8. 2013
    ..Greater experience is necessary to fully comprehend risks, comparative benefits, and complication of ocular phototherapy of ocular tumours...
  6. doi request reprint Management of radiation maculopathy
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ophthalmic Res 48:26-31. 2012
    ..Use of periocular steroid during plaque brachytherapy may prevent radiation maculopathy over the short term. Newer designs and techniques of delivering radiation to the eye need to be explored...
  7. doi request reprint Chromosome 3 status in uveal melanoma: a comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Invest Ophthalmol Vis Sci 53:3331-9. 2012
    ..To compare fluorescence in situ hybridization (FISH) using a centromeric probe for chromosome 3 (CEP3) and 3p26 locus-specific probe with single-nucleotide polymorphism array (SNP-A) analysis in the detection of high-risk uveal melanoma...
  8. ncbi request reprint Metastatic uveal melanoma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:143-50, ix. 2005
    ..In general, the survival with metastatic uveal melanoma is poor, with a median survival of less than 6 months...
  9. ncbi request reprint Eccrine hidrocystoma of the eyelid
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, USA
    Eye (Lond) 19:77-9. 2005
    ..To report on the clinical features of eccrine hidrocystoma involving the eyelid...
  10. ncbi request reprint Sebaceous adenoma of the eyelid in Muir-Torre syndrome
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cliveland Clinic Foundation, OH 44195, USA
    Arch Ophthalmol 123:562-5. 2005
  11. doi request reprint Uveal melanoma: trends in incidence, treatment, and survival
    Arun D Singh
    Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ophthalmology 118:1881-5. 2011
    ..To determine trends in incidence, treatment, and survival with primary uveal melanoma in the United States over a 36-year period from 1973 to 2008...
  12. ncbi request reprint Primary lymphoma of the central nervous system
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:199-207, x. 2005
    ..This article discusses primary lymphoma of the central nervous system, which is a variant of extranodal non-Hodgkin's lymphoma that arises from specific sites such as the brain, spinal cord, meninges, or eyes...
  13. ncbi request reprint Uveal melanoma: epidemiologic aspects
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:75-84, viii. 2005
    ....
  14. ncbi request reprint Uveal melanoma: genetic aspects
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:85-97, viii. 2005
    ..This article reviews the clinical genetics, cytogenetics, and molecular genetic aspects of uveal melanoma...
  15. ncbi request reprint Retinal vascular tumors
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:167-76, x. 2005
    ....
  16. ncbi request reprint Estimating the risk of malignant transformation of a choroidal nevus
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmology 112:1784-9. 2005
    ..To estimate the risk of malignant transformation of a choroidal nevus in the white population...
  17. ncbi request reprint Choroidal hemangioma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:151-61, ix. 2005
    ..Diffuse choroidal hemangiomas are usually evident at birth and generally occur as a part of neuro-oculo-cutaneous hemangiomatosis (Sturge-Weber syndrome)...
  18. pmc Reduced expression of autotaxin predicts survival in uveal melanoma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Ophthalmol 91:1385-92. 2007
    ..In an effort to identify patients with uveal melanoma at high risk of metastasis, the authors undertook correlation of gene expression profiles with histopathology data and tumour-related mortality...
  19. ncbi request reprint Chromosomal 3 and 8 status within hepatic metastasis of uveal melanoma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 133:1223-7. 2009
    ..However, it is not known whether the primary tumor cells maintain these aggressive attributes at the metastatic sites...
  20. ncbi request reprint The collaborative ocular melanoma study
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmol Clin North Am 18:129-42, ix. 2005
    ..Because the randomized design of the COMS was unique, no attempt is made to make any comparison with the results of previous non-controlled studies...
  21. doi request reprint Fourier domain optical coherence tomographic and auto-fluorescence findings in indeterminate choroidal melanocytic lesions
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Ophthalmol 94:474-8. 2010
    ..To compare detection rates of drusen and subretinal fluid by Fourier domain optical coherence tomography (FD OCT) and orange pigment by fundus autofluorescence (FAF) with ophthalmoscopy in indeterminate choroidal melanocytic lesions...
  22. ncbi request reprint Estimating choroidal melanoma volume: comparison of methods
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmology 114:1212-4. 2007
    ..To evaluate published methods of estimating choroidal melanoma volume...
  23. ncbi request reprint Small choroidal melanocytic lesions: features predictive of growth
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmology 113:1032-9. 2006
    ..To evaluate clinical features at presentation of small choroidal melanocytic lesions that were predictive of growth...
  24. doi request reprint Uveal lymphoma: clinical features, diagnostic studies, treatment selection, and outcomes
    Mary E Aronow
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio
    Ophthalmology 121:334-41. 2014
    ..To describe the clinical features, ancillary diagnostic studies, and treatment selection in a cohort of patients with uveal lymphoma...
  25. doi request reprint Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease
    Susan Achberger
    Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, United States
    Mol Immunol 58:182-6. 2014
    ..The immune response has been implicated in the control of uveal melanoma progression. Epigenetic mechanisms mediated by specific microRNAs (miRs) regulate immune responses...
  26. doi request reprint The impact of intravitreal bevacizumab therapy on choroidal melanoma
    Breno R Lima
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Ophthalmol 151:323-8.e2. 2011
    ..To describe the clinical course and ancillary findings of 3 patients with choroidal melanoma who inadvertently received multiple intravitreal injections of bevacizumab for a presumed diagnosis of choroidal neovascular membrane...
  27. doi request reprint Ocular adnexal lymphoma: assessment of a tumor-node-metastasis staging system
    Mary E Aronow
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ophthalmology 120:1915-9. 2013
    ..To assess distribution, correlations, and prognostic effect of tumor (T), node (N), and metastasis (M) staging on relapse and survival...
  28. doi request reprint Elevated blood β-2 microglobulin is associated with tumor monosomy-3 in patients with primary uveal melanoma
    Pierre L Triozzi
    Taussig Cancer Institute, Cleveland, Ohio 44195, USA
    Melanoma Res 23:1-7. 2013
    ..In conclusion, measurement of blood levels of β2M in patients with primary uveal melanoma may have prognostic value and may help guide surveillance and adjuvant therapy recommendations...
  29. pmc Paraneoplastic vitelliform retinopathy: clinicopathologic correlation and review of the literature
    Mary E Aronow
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Surv Ophthalmol 57:558-64. 2012
    ..For the first time, histopathology from enucleation specimens provides a clinicopathologic disease correlation with focal abnormalities in the inner nuclear and outer plexiform layers...
  30. doi request reprint Plaque brachytherapy for uveal melanoma: a vision prognostication model
    Niloufer Khan
    Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 84:e285-90. 2012
    ..To generate a vision prognostication model after plaque brachytherapy for uveal melanoma...
  31. doi request reprint Monosomy 3 by FISH in uveal melanoma: variability in techniques and results
    Mary Aronow
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Surv Ophthalmol 57:463-73. 2012
    ..FISH is a widely available, versatile technology, and when performed optimally has the potential to be a valuable tool for determining the prognosis of uveal melanoma...
  32. ncbi request reprint Variation of monosomy 3 status within uveal melanoma
    Lynn Schoenfield
    Department of Anatomic Pathology, and the Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 133:1219-22. 2009
    ..Monosomy 3, one such variable, can be determined using fluorescence in situ hybridization, either on enucleated samples, fine-needle aspiration biopsy, or tumor sample obtained by vitrector...
  33. doi request reprint 3D Spectral domain optical coherence tomography findings in choroidal tumors
    Kaori Sayanagi
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Eur J Ophthalmol 21:271-5. 2011
    ..To report the optical coherence tomographic features differentiating choroidal nevus from choroidal melanoma by 3D spectral-domain optical coherence tomography (SD-OCT) and OCT characteristics of other choroidal tumors...
  34. pmc Ciliary body metastasis masquerading as scleritis
    Brian J Lee
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Ophthalmol 91:1582, 1649. 2007
  35. pmc The association of blood angioregulatory microRNA levels with circulating endothelial cells and angiogenic proteins in patients receiving dacarbazine and interferon
    Pierre L Triozzi
    Taussig Cancer Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Transl Med 10:241. 2012
    ..The association of blood levels of microRNAs (miRs) implicated in angiogenesis with circulating endothelial cells (CEC) and with angiogenic proteins was examined in patients administered drugs with anti-angiogenic activity...
  36. doi request reprint Dosimetric benefit of a new ophthalmic radiation plaque
    Gaurav Marwaha
    Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Int J Radiat Oncol Biol Phys 84:1226-30. 2012
    ..To determine whether the computed dosimetry of a new ophthalmic plaque, EP917, when compared with the standard Collaborative Ocular Melanoma Study (COMS) plaques, could reduce radiation exposure to vision critical structures of the eye...
  37. doi request reprint Male breast carcinoma metastatic to the choroid: report of 3 cases and review of the literature
    Christopher T Hood
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Eur J Ophthalmol 21:459-67. 2011
    ..To describe breast cancer as a source of choroidal metastasis in men and highlight the diagnostic and treatment modalities...
  38. doi request reprint Verteporfin photodynamic therapy of six eyes with retinal capillary haemangioma
    Reecha Sachdeva
    Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA
    Acta Ophthalmol 88:e334-40. 2010
    ..Single-centre consecutive interventional case series by retrospective chart review to evaluate the efficacy of verteporfin (Visudyne™) photodynamic therapy (PDT) of retinal capillary haemangioma (RCH)...
  39. ncbi request reprint Transient closure of a retinal capillary hemangioma with verteporfin photodynamic therapy
    Sophie J Bakri
    Cole Eye Institute, Cleveland Clinic Foundation, Ohio 44195, USA
    Retina 25:1103-4. 2005
  40. pmc The evolving role of radiation therapy in the management of malignant melanoma
    Niloufer Khan
    Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Int J Radiat Oncol Biol Phys 80:645-54. 2011
    ..The newer clinical data along with emerging radiobiological data indicate that radiotherapy is likely to play a greater role in melanoma management and should be considered as a treatment option...
  41. ncbi request reprint OCT and ultrasound biomicroscopic findings in iris arteriovenous malformation
    Brian J Lee
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ophthalmic Surg Lasers Imaging 39:426-8. 2008
    ..The authors report anterior segment optical coherence tomography and ultrasound biomicroscopic features in two patients with iris arteriovenous malformation...
  42. ncbi request reprint Clinical characteristics of 95 patients with ocular adnexal and uveal lymphoma: treatment outcomes in extranodal marginal zone subtype
    Craig A Portell
    Department of Hematologic Oncology and Blood Disorders, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH Electronic address
    Clin Lymphoma Myeloma Leuk 14:203-10. 2014
    ..Involved-field radiotherapy (IFRT) is the standard of care for unilateral disease, but the optimal management of more extensive disease is unclear...
  43. doi request reprint Teletherapy: advanced techniques
    Abigail Stockham
    Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:15-28. 2013
    ....
  44. doi request reprint Brachytherapy
    Gaurav Marwaha
    Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:29-35. 2013
    ..This chapter will highlight the history of brachytherapy for the treatment of intraocular tumors, current practice including isotopes and plaques utilized, as well as a comprehensive treatment planning and physics review. ..
  45. doi request reprint Circulating tumor cells in uveal melanoma
    Virginia Torres
    Taussig Cancer Institute, Cleveland Clinic Foundation, Ohio, USA
    Future Oncol 7:101-9. 2011
    ..However, more research on the biology of uveal melanoma as well as improvements upon the current technologies are needed...
  46. doi request reprint Targeted therapy for uveal melanoma
    Pierre L Triozzi
    Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, United States
    Cancer Treat Rev 34:247-58. 2008
    ..Clinical trials of some of these approaches have been initiated in patients with metastatic uveal melanoma as well as in the adjuvant setting after primary therapy...
  47. ncbi request reprint Imaging of iris lesions with high-speed optical coherence tomography
    Sophie J Bakri
    From the Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Ophthalmic Surg Lasers Imaging 38:27-34. 2007
    ..To image and measure iris tumors with optical coherence tomography (OCT)...
  48. doi request reprint Retinoblastoma with autoinfarction presenting as orbital cellulitis
    Reecha Sachdeva
    Cleveland Clinic, Cole Eye Institute, Cleveland, Ohio 44124, USA
    J AAPOS 15:302-4. 2011
    ..This case highlights the importance of complete ocular evaluation and proper imaging modalities in children presenting with orbital cellulitis...
  49. ncbi request reprint Iris melanoma arising in iris nevus in oculo(dermal) melanocytosis
    Ying Qian
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Surv Ophthalmol 53:411-5. 2008
    ..It is recommended that patients with oculo(dermal) melanocytosis be followed for the occurrence of uveal melanoma...
  50. doi request reprint Radiation therapy: conjunctival and eyelid tumors
    Mary E Aronow
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:85-93. 2013
    ....
  51. doi request reprint Radiation therapy: orbital tumors
    Gaurav Marwaha
    Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:94-101. 2013
    ..In this chapter, we review an array of non-neoplastic entities and orbital tumors, for which there exists a role for radiation, and the radiotherapeutic techniques and applications in their management. ..
  52. ncbi request reprint Tuberous sclerosis complex: genotype/phenotype correlation of retinal findings
    Mary E Aronow
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmology 119:1917-23. 2012
    ..To evaluate genotype/phenotype correlations in individuals with astrocytic hamartoma (AH) and retinal achromic patch (AP) in the setting of tuberous sclerosis complex (TSC)...
  53. doi request reprint Blood biomarkers for uveal melanoma
    Pierre L Triozzi
    Taussig Cancer Center, Cleveland, OH, USA
    Future Oncol 8:205-15. 2012
    ..The stage is set to translate the advances made in understanding the molecular characteristics of uveal melanoma in order to identify and test clinically useful blood biomarkers of tumor dissemination and/or progression...
  54. doi request reprint Ocular surface squamous neoplasia in an anophthalmic socket 60 years after enucleation
    Edgar M Espana
    Department of Cornea, External Disease and Refractive Surgery, The Cleveland Clinic, Cleveland, Ohio, USA
    Surv Ophthalmol 56:539-43. 2011
    ..Our case emphasizes the importance of a thorough examination of the anophthalmic socket, including upper and lower lid eversion...
  55. doi request reprint Bilateral panocular involvement with mantle-cell lymphoma
    Aimee V Chappelow
    Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Clin Oncol 26:1167. 2008
  56. doi request reprint Low dose irradiation for diffuse choroidal hemangioma
    Lorna W Grant
    Cleveland Clinic, Cole Eye Institute, Cleveland, Ohio, USA
    Ophthalmic Genet 29:186-8. 2008
    ..In the past this has been challenging. Herein, we describe a case of Sturge-Weber Syndrome with diffuse choroidal hemangioma which was successfully treated with low dose lens-sparing external beam radiotherapy...
  57. ncbi request reprint Sunlight exposure and pathogenesis of uveal melanoma
    Arun D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Surv Ophthalmol 49:419-28. 2004
    ..In the following review, we examine physiologic, epidemiological, and genetic data in order to determine the role of sunlight exposure in the pathogenesis of uveal melanoma...
  58. doi request reprint Topical chemotherapy for ocular surface squamous neoplasia: current status
    Ricardo Sepulveda
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Ophthalmol 94:532-5. 2010
    ..5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient...
  59. doi request reprint Dosimetric comparison of 106Ru and 125I plaques for treatment of shallow (<or=5 mm) choroidal melanoma lesions
    D A Wilkinson
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Br J Radiol 81:784-9. 2008
    ..This comparison shows that, for tumours not exceeding 5 mm in thickness, the use of (106)Ru plaques has the potential to reduce the radiation dose to nearby normal structures and possibly lower the risk of radiation-induced visual loss...
  60. doi request reprint Introduction to radiotherapy and standard teletherapy techniques
    Ehsan H Balagamwala
    Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:1-14. 2013
    ....
  61. doi request reprint Radiation therapy: anterior segment complications
    Carlos A Medina Mendez
    Vitreoretinal Service, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dev Ophthalmol 52:102-13. 2013
    ..These can vary from ocular surface irritation to blindness and can be subdivided into acute (<4 weeks) and chronic (>4 weeks). Prevention and management is also discussed and subdivided by affected tissue. ..
  62. ncbi request reprint Unusual macular degeneration following breast cancer
    Ron Margolis
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Acta Ophthalmol Scand 85:686-7. 2007
  63. ncbi request reprint Plexiform pigmented schwannoma of the uvea
    Egbert Saavedra
    Cole Eye Institute, Cleveland Clinic Foundation, Ohio 44195, USA
    Surv Ophthalmol 51:162-8. 2006
    ..In this article, we review the clinical and histopathological findings of a sporadic plexiform pigmented schwannoma involving the iris, ciliary body, and the choroid...
  64. ncbi request reprint Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma
    Anat Galor
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Ophthalmol 144:45-49. 2007
    ..To report on the development of visually significant maculopathy associated with blood-brain barrier disruption (BBBD) therapy for the treatment of central nervous system (CNS) lymphoma...
  65. ncbi request reprint A unique presentation of grouped congenital hypertrophy of the retinal pigment epithelium
    Mary E Turell
    Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ophthalmic Genet 32:162-4. 2011
    ....
  66. doi request reprint Orbital inflammation in IgG4-related sclerosing disease
    Theodore Pasquali
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Orbit 30:258-60. 2011
    ..The 2 cases illustrate the widely varying clinical characteristics of this elusive disease...
  67. doi request reprint Congenital intradiploic arachnoid cyst presenting as painless proptosis
    Reecha Sachdeva
    Cole Eye Insitute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J AAPOS 15:601-3. 2011
    ..To our knowledge, this is the first such case reported in a child. Although this cyst has been described in the occipital and frontal bones, this is the first description of occurrence in the sphenoid bone...
  68. doi request reprint Conjunctival lichen planus simulating ocular surface squamous neoplasia
    Jerome C Ramos-Esteban
    Cole Eye Institute, Pathology Department, Cleveland Clinic, OH, USA
    Cornea 28:1181-3. 2009
    ..To describe the history and clinical presentation of a case of conjunctival lichen planus simulating ocular surface squamous neoplasia (OSSN)...
  69. doi request reprint Myeloma-associated orbital amyloidosis
    Jeff M Goshe
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Orbit 29:274-7. 2010
    ..The clinical signs and symptoms, histopathologic findings, and radiographic features of orbital amyloidosis are discussed...
  70. doi request reprint Iris varix: report of a case and review of iris vascular anomalies
    Erin Broaddus
    Department of Ophthalmic Oncology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Surv Ophthalmol 54:118-27. 2009
    ..We also report a case of an iris varix, confirmed by histopathological and immunohistochemical examination. Comparative features of each subtype of vascular anomaly are discussed...
  71. pmc The Zimmerman-McLean-Foster hypothesis: 25 years later
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Ophthalmol 88:962-7. 2004
    ..In this review, the Zimmerman-McLean-Foster hypothesis is explored in the light of current clinical, epidemiological, statistical, and experimental evidence...
  72. pmc Photodynamic therapy of circumscribed choroidal haemangioma
    A D Singh
    Department of Ophthalmic Oncology, Cole Eye Institute i3 129, Cleveland Clinic Foundation, 9500 Euclid Avenue, OH 44195, USA
    Br J Ophthalmol 88:1414-8. 2004
    ..To evaluate efficacy of verteporfin ocular photodynamic therapy (PDT) in treatment of 10 patients with a symptomatic circumscribed choroidal haemangioma...
  73. ncbi request reprint Ciliary body naevus
    M Taban
    Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
    Eye (Lond) 21:1528-30. 2007
    ..To describe clinical, ultrasound biomicroscopy (UBM), and histopathologic characteristics of benign melanocytic tumors of the ciliary body...
  74. ncbi request reprint Clinicopathologic reports, case reports, and small case series: enucleation following transpupillary thermotherapy of choroidal melanoma: clinicopathologic correlations
    Arun D Singh
    Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 121:397-400. 2003
  75. ncbi request reprint Incidence of uveal melanoma in the United States: 1973-1997
    Arun D Singh
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmology 110:956-61. 2003
    ..To determine the incidence of primary uveal melanoma in the United States over a 25-year period from 1973 to 1997...
  76. ncbi request reprint Survival rates with uveal melanoma in the United States: 1973-1997
    Arun D Singh
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Ophthalmology 110:962-5. 2003
    ..To determine variations in 5-year relative survival rates with primary uveal melanoma in the United States over a 25-year period from 1973 to 1997...
  77. ncbi request reprint Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations
    Carol L Shields
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 109:225-34. 2002
    ..The objective of this report was to evaluate ocular and systemic outcomes after primary transpupillary thermotherapy for choroidal melanoma and to identify the limitations of this treatment method...
  78. ncbi request reprint Treatment of retinal capillary hemangioma
    Arun D Singh
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 109:1799-806. 2002
    ..To report on the methods of treatment and the visual outcome of eyes with retinal capillary hemangioma (RCH)...
  79. ncbi request reprint Uveal and cutaneous involvement in paraneoplastic melanocytic proliferation
    Arun D Singh
    Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, England
    Arch Ophthalmol 121:1637-40. 2003
  80. ncbi request reprint Growth of small tumors
    Arun D Singh
    Ophthalmology 113:1061.e1-4. 2006
  81. ncbi request reprint Comments on: basal cell carcinoma of the eyelids
    Victoria M L Cohen
    Compr Ophthalmol Update 8:15-6. 2007
  82. ncbi request reprint Imaging techniques for uveal melanoma
    Sophie J Bakri
    Department of Radiation Oncology, University of Utah Medical Center, Salt Lake City, UT 84112, USA
    Int Ophthalmol Clin 46:1-13. 2006
  83. ncbi request reprint Infrared thermotherapy: from laboratory to clinic
    Hanneke G Journee-de Korver
    Department of Ophthalmology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands
    Ophthalmol Clin North Am 18:99-110, viii-ix. 2005
    ..The indications for chemoreduction, thermochemotherapy, and thermotherapy for retinoblastoma remain under investigation...
  84. ncbi request reprint Two discrete choroidal melanomas in an eye with ocular melanocytosis
    Santosh G Honavar
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Surv Ophthalmol 47:36-41. 2002
    ..In conclusion, multifocal choroidal melanoma is rare and may be related to underlying ocular melanocytosis...
  85. ncbi request reprint Ocular adnexal lymphoma. What is the evidence for an infectious aetiology?
    Victoria M L Cohen
    Br J Ophthalmol 92:446-8. 2008
  86. pmc Bilateral exudative retinopathy as the initial manifestation of retinitis pigmentosa
    Arun D Singh
    Br J Ophthalmol 86:116-7. 2002
  87. ncbi request reprint Anatomical eye model
    Richard Keeler
    Museum of the Royal College of Ophthalmologists, London, UK
    Br J Ophthalmol 92:1179. 2008
  88. doi request reprint Primary transpupillary thermotherapy of "small" choroidal melanoma: is it safe?
    Arun D Singh
    Br J Ophthalmol 92:727-8. 2008
  89. ncbi request reprint The British Journal of Ophthalmology. At a glance
    Harminder S Dua
    Br J Ophthalmol 92:869. 2008
  90. ncbi request reprint Solitary retinal capillary hemangioma: lack of genetic evidence for von Hippel-Lindau disease
    Arun D Singh
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Ophthalmic Genet 23:21-7. 2002
    ..To report the results of genetic testing for von Hippel-Lindau (VHL) disease in patients presenting with solitary retinal capillary hemangioma (RCH)...
  91. ncbi request reprint Prenatal diagnosis of retinoblastoma
    Arun D Singh
    Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    J Pediatr Ophthalmol Strabismus 40:222-4. 2003
  92. ncbi request reprint Lack of response to chemoreduction in presumed well differentiated retinoblastoma
    Arun D Singh
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Pediatr Ophthalmol Strabismus 39:107-9. 2002
  93. ncbi request reprint Postenucleation adjuvant therapy in high-risk retinoblastoma
    Santosh G Honavar
    Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 120:923-31. 2002
    ..The main purpose of this study was to determine the efficacy of postenucleation adjuvant therapy in preventing metastasis in cases of high-risk retinoblastoma...
  94. ncbi request reprint Orbital melanoma metastatic from contralateral choroid: management by complete surgical resection
    Jerry A Shields
    Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmic Surg Lasers 33:416-20. 2002
    ..The contralateral orbit can be the site of late metastasis from choroidal melanoma. In rare instances, an orbital metastasis can be completely removed surgically without subjecting the patient to orbital irradiation...
  95. ncbi request reprint Management of advanced retinoblastoma
    Santosh G Honavar
    Ocular Oncology Service and SightSavers International Children s Eye Cancer Center, LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad 500034, India
    Ophthalmol Clin North Am 18:65-73, viii. 2005
    ..This review provides an update on the current management of advanced retinoblastoma...
  96. ncbi request reprint Pigmented medulloepithelioma of the ciliary body
    Jerry A Shields
    Arch Ophthalmol 120:207-10. 2002