Klaus Sellheyer

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi "Hidradenitis suppurativa" is acne inversa! An appeal to (finally) abandon a misnomer
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Dermatol 44:535-40. 2005
  2. ncbi Ber-EP4 enhances the differential diagnostic accuracy of cytokeratin 7 in pagetoid cutaneous neoplasms
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Cutan Pathol 35:366-72. 2008
  3. ncbi Histopathologic evaluation of alopecias
    Klaus Sellheyer
    Departments of Dermatology and Pathology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Dermatopathol 28:236-59. 2006
  4. ncbi Differences in biopsy techniques of actinic keratoses by plastic surgeons and dermatologists: a histologically controlled pilot study
    Klaus Sellheyer
    Department of Anatomic Pathology, Section of Dermatopathology, The Cleveland Clinic Foundation, OH 44195, USA
    Arch Dermatol 142:455-9. 2006
  5. ncbi When to ask your dermatopathologist to evaluate for surgical margins and when not: a matter of confusion for dermatologists and dermatopathologists alike
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Acad Dermatol 52:1095-7. 2005
  6. ncbi "Lesion," "rule out...," and other vagaries of filling out pathology requisition forms
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Acad Dermatol 52:914-5. 2005
  7. ncbi A retrospective biopsy study of the clinical diagnostic accuracy of common skin diseases by different specialties compared with dermatology
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Acad Dermatol 52:823-30. 2005
  8. ncbi Evaluation of surgical margins in melanocytic lesions: a survey among 152 dermatopathologists
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Cutan Pathol 32:293-9. 2005
  9. ncbi DNA microarrays: from structural genomics to functional genomics. The applications of gene chips in dermatology and dermatopathology
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Acad Dermatol 51:681-92; quiz 693-6. 2004
  10. ncbi Mechanisms of laser hair removal: could persistent photoepilation induce vitiligo or defects in wound repair?
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dermatol Surg 33:1055-65. 2007

Collaborators

Detail Information

Publications27

  1. ncbi "Hidradenitis suppurativa" is acne inversa! An appeal to (finally) abandon a misnomer
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Dermatol 44:535-40. 2005
    ..We suggest that the term "hidradenitis suppurativa" for this disease should (finally) be abandoned in favour of "acne inversa"...
  2. ncbi Ber-EP4 enhances the differential diagnostic accuracy of cytokeratin 7 in pagetoid cutaneous neoplasms
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Cutan Pathol 35:366-72. 2008
    ..Here we report its application in the differential diagnosis of cutaneous pagetoid neoplasms...
  3. ncbi Histopathologic evaluation of alopecias
    Klaus Sellheyer
    Departments of Dermatology and Pathology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Dermatopathol 28:236-59. 2006
    ..This review also discusses important pathogenetic concepts, such as stem cell failure...
  4. ncbi Differences in biopsy techniques of actinic keratoses by plastic surgeons and dermatologists: a histologically controlled pilot study
    Klaus Sellheyer
    Department of Anatomic Pathology, Section of Dermatopathology, The Cleveland Clinic Foundation, OH 44195, USA
    Arch Dermatol 142:455-9. 2006
    ..To compare differences in biopsy techniques of actinic keratoses between dermatologists and plastic surgeons...
  5. ncbi When to ask your dermatopathologist to evaluate for surgical margins and when not: a matter of confusion for dermatologists and dermatopathologists alike
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Acad Dermatol 52:1095-7. 2005
  6. ncbi "Lesion," "rule out...," and other vagaries of filling out pathology requisition forms
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Am Acad Dermatol 52:914-5. 2005
  7. ncbi A retrospective biopsy study of the clinical diagnostic accuracy of common skin diseases by different specialties compared with dermatology
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Acad Dermatol 52:823-30. 2005
    ..With the recent trend for nondermatologists to treat dermatologic disorders, this retrospective biopsy study reviews the accuracy of the clinical diagnosis of physicians of different specialties performing surgical dermatologic procedures...
  8. ncbi Evaluation of surgical margins in melanocytic lesions: a survey among 152 dermatopathologists
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Cutan Pathol 32:293-9. 2005
    ..Although guidelines are established for reporting tissue specimens of melanomas, such guidelines are not available for reporting surgical margins of benign melanocytic lesions...
  9. ncbi DNA microarrays: from structural genomics to functional genomics. The applications of gene chips in dermatology and dermatopathology
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Acad Dermatol 51:681-92; quiz 693-6. 2004
    ..cDNA microarrays will shape the diagnostic approach of the dermatology and the dermatopathology of the future and may lead to new therapeutic options...
  10. ncbi Mechanisms of laser hair removal: could persistent photoepilation induce vitiligo or defects in wound repair?
    Klaus Sellheyer
    Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dermatol Surg 33:1055-65. 2007
    ..Current laser hair removal modalities achieve a long-term but not persistent (irreversible) hair loss...
  11. ncbi The ventral proximal nail fold: stem cell niche of the nail and equivalent to the follicular bulge--a study on developing human skin
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 39:835-43. 2012
    ..The areas of proliferative activity were additionally examined using labeling with Ki-67...
  12. ncbi Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Acad Dermatol 63:93-113. 2010
    ..Whereas keratinocytic bulge stem cells are well characterized, comparably little is known about cutaneous mesenchymal stem cells. The follicular connective tissue sheath is proposed as a niche for dermal stem cells...
  13. ncbi Expression of embryonic stem cell markers SOX2 and nestin in dermatofibrosarcoma protuberans and dermatofibroma
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 38:415-9. 2011
    ..The distribution pattern differs only in early embryogenesis, when nestin but not SOX2 is also expressed throughout the entire interfollicular dermis. We speculated that DFSP would not only be nestin-positive but also SOX2-positive...
  14. ncbi Does the peritumoral stroma of basal cell carcinoma recapitulate the follicular connective tissue sheath?
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 38:551-9. 2011
    ..This study examines the expression of this neuroepithelial stem cell protein in trichoblastoma/trichoepithelioma and in basal cell carcinoma (BCC), which is increasingly being viewed as follicular in nature...
  15. ncbi Cutaneous mesenchymal stem cells: status of current knowledge, implications for dermatopathology
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 37:624-34. 2010
    ....
  16. ncbi Expression pattern of GATA-3 in embryonic and fetal human skin suggests a role in epidermal and follicular morphogenesis
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 37:357-61. 2010
    ..While the expression profile of GATA-3 is delineated for the mouse, little is known about its expression in the adult human hair follicle and no studies are published about its distribution during human cutaneous embryogenesis...
  17. ncbi Follicular stem cell marker PHLDA1 (TDAG51) is superior to cytokeratin-20 in differentiating between trichoepithelioma and basal cell carcinoma in small biopsy specimens
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 38:542-50. 2011
    ..In the current study, we examined the expression of a recently characterized follicular stem cell marker, PHLDA1 (pleckstrin homology-like domain, family A, member 1), also known as TDAG51 (T-cell death-associated gene 51)...
  18. ncbi Blimp-1: a marker of terminal differentiation but not of sebocytic progenitor cells
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 37:362-70. 2010
    ....
  19. ncbi Skin mesenchymal stem cells: prospects for clinical dermatology
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Acad Dermatol 63:859-65. 2010
    ..In line with the cancer stem cell hypothesis, the potential contributions to dermatopathology include a conceptual understanding of mesenchymal skin-based neoplasms as evolving from a genetically altered dermal stem cell clone...
  20. ncbi Stem cell markers can help identify adnexal tumor differentiation when evaluated in the context of morphology: methodology matters
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Cutan Pathol 38:460-74. 2011
    ..A combined approach of modern morphology with basic science holds potential to advance one important aspect of our field further with the final goal of logically classifying adnexal tumors based on stem cell biology...
  21. ncbi What causes acne inversa (or hidradenitis suppurativa)?--the debate continues
    Klaus Sellheyer
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
    J Cutan Pathol 35:701-3. 2008
  22. ncbi A case of recurrent pseudolymphomatous folliculitis: A mimic of cutaneous lymphoma
    Eun Ji Kwon
    Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA
    J Am Acad Dermatol 60:994-1000. 2009
    ....
  23. ncbi Basal cell (trichoblastic) carcinoma common expression pattern for epithelial cell adhesion molecule links basal cell carcinoma to early follicular embryogenesis, secondary hair germ, and outer root sheath of the vellus hair follicle: A clue to the adnexa
    Klaus Sellheyer
    Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Acad Dermatol 58:158-67. 2008
    ..Basal cell carcinoma (BCC) is still viewed by many dermatologists as a tumor of the interfollicular epidermis, although references were made early in the dermatopathologic literature to the resemblance of BCC to the hair follicle...
  24. ncbi Solitary plaque on the scalp as a primary manifestation of Hodgkin lymphoma: a case report and review of the literature
    Ibrahim Khalifeh
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
    J Cutan Pathol 36:80-5. 2009
    ..In either case, primary or secondary cutaneous Hodgkin disease is an extreme rarity. The literature is critically reviewed...
  25. ncbi Monoclonal antibody Ber-EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma
    Dieter Krahl
    Institut für Dermatohistologie, Heidelberg, Germany
    J Cutan Pathol 34:782-7. 2007
    ..In this study, we report its application in the differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and basal cell carcinoma...
  26. ncbi Dermatofibroma: upregulation of syndecan-1 expression in mesenchymal tissue
    Klaus Sellheyer
    The Jefferson Center for Dermatopathology, Department of Pathology, Thomas Jefferson University, Philadelphia, PA, USA
    Am J Dermatopathol 25:392-8. 2003
    ....
  27. ncbi Pathogenesis of solar elastosis: synthesis or degradation?
    Klaus Sellheyer
    The Jefferson Center for Dermatopathology, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA
    J Cutan Pathol 30:123-7. 2003