Ofer Reizes

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint The role of syndecans in the regulation of body weight and synaptic plasticity
    Ofer Reizes
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, United States
    Int J Biochem Cell Biol 40:28-45. 2008
  2. pmc Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
    Qiao Zheng
    Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, Ohio 44195, USA Department of Nutritional Sciences, The University of Texas, Austin, Texas, USA Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, Texas, USA Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA ImageIQ, Cleveland, Ohio, USA Case Comprehensive Cancer Center, Cleveland, Ohio, USA
    Endocr Relat Cancer 20:797-808. 2013
  3. pmc Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors
    Qiao Zheng
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, USA
    J Cancer Res Clin Oncol 138:1607-12. 2012
  4. ncbi request reprint Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight
    X Eric Hu
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, USA
    J Pharmacol Exp Ther 324:206-13. 2008
  5. pmc Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival
    Qiao Zheng
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, Ohio 44195, USA
    Endocr Relat Cancer 18:491-503. 2011
  6. pmc Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition
    Jordan R Beach
    Department of Cell Biology, Cleveland Clinic, Cleveland, OH 44195, USA
    Proc Natl Acad Sci U S A 108:17991-6. 2011

Collaborators

Detail Information

Publications6

  1. ncbi request reprint The role of syndecans in the regulation of body weight and synaptic plasticity
    Ofer Reizes
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, United States
    Int J Biochem Cell Biol 40:28-45. 2008
    ..As part of this review, we will highlight how syndecan-3 can mediate the activity of adiposity signals, such as leptin, and facilitate changes in neuronal plasticity...
  2. pmc Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
    Qiao Zheng
    Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, Ohio 44195, USA Department of Nutritional Sciences, The University of Texas, Austin, Texas, USA Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, Texas, USA Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA ImageIQ, Cleveland, Ohio, USA Case Comprehensive Cancer Center, Cleveland, Ohio, USA
    Endocr Relat Cancer 20:797-808. 2013
    ..Given the emergence of NANOG as a pro-carcinogenic protein in multiple cancers, these studies suggest that inhibition of LEPR may be a promising therapeutic approach to inhibit NANOG and thereby neutralize CSC functions...
  3. pmc Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors
    Qiao Zheng
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, USA
    J Cancer Res Clin Oncol 138:1607-12. 2012
    ..The aim of the present study was to assess cyclin D1 expression in spontaneous tumors that develop in the MMTV-Wnt-1 transgenic mice and interrogate the in vivo effect of leptin...
  4. ncbi request reprint Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight
    X Eric Hu
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, USA
    J Pharmacol Exp Ther 324:206-13. 2008
    ..The effect is dose-dependent and appears to be partially driven by a reduction in food intake. Finally, these studies show the utility of a medicinal chemistry approach to address an important biological and pharmacological question...
  5. pmc Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival
    Qiao Zheng
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, NC10, Cleveland, Ohio 44195, USA
    Endocr Relat Cancer 18:491-503. 2011
    ..These studies provide critical new insight on the role of leptin in tumor growth and implicate LepRb as a CSC target...
  6. pmc Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition
    Jordan R Beach
    Department of Cell Biology, Cleveland Clinic, Cleveland, OH 44195, USA
    Proc Natl Acad Sci U S A 108:17991-6. 2011
    ..These studies indicate that transition between myosin IIC/myosin IIB expression is a critical feature of EMT that contributes to increases in invasive behavior...