Research Topics
| EMILIO DANIEL POGGIOSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
Research Grants
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Detail Information
Publications
Demographic and clinical characteristics associated with glomerular filtration rates in living kidney donorsEmilio D Poggio
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland, Ohio 44195, USA
Kidney Int 75:1079-87. 2009..49+/-0.61 ml/min per 1.73 m(2) per decade of testing. Our study shows that age and gender are important factors determining normal GFR in living kidney donors...
The science of Stewardship: due diligence for kidney donors and kidney function in living kidney donation--evaluation, determinants, and implications for outcomesEmilio D Poggio
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Clin J Am Soc Nephrol 4:1677-84. 2009....
Evaluation of renal function in transplantationEmilio D Poggio
Department of Nephrology and Hypertension and Transplant Center, Cleveland Clinic, Cleveland, OH 44195, USA
Transplantation 84:131-6. 2007..The performance of commonly used estimation equations and methods for measuring kidney function in renal and liver transplant patients are overviewed here along with their potential roles in clinical transplantation...
Donor kidney volume and outcomes following live donor kidney transplantationE D Poggio
Department of Nephrology and Hypertension, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Transplant 6:616-24. 2006..The findings suggest that (1) transplantation of larger kidneys confers an outcome advantage and (2) larger kidneys should be preferred when selecting from otherwise similar living donors...
Assessing glomerular filtration rate by estimation equations in kidney transplant recipientsE D Poggio
Department of Nephrology and Hypertension, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Transplant 6:100-8. 2006..In conclusion, the overall performance of the MDRD equation was superior to the Nankivell and Cockcroft-Gault formulas in renal transplant recipients including subjects treated with CNI...
Can we do better than a single estimated GFR threshold when screening for chronic kidney disease?E D Poggio
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Kidney Int 72:534-6. 2007..However, data derived from healthy individuals challenge this approach and suggest that age- and gender-specific reference values may be more useful in the screening setting...
Performance of the Cockcroft-Gault and modification of diet in renal disease equations in estimating GFR in ill hospitalized patientsEmilio D Poggio
Department of Nephrology and Hypertension, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Am J Kidney Dis 46:242-52. 2005..The Modification of Diet in Renal Disease (MDRD) equation and Cockcroft-Gault (CG) formula are widely used to estimate renal function in sick hospitalized patients; however, neither method has been validated in this setting...
Pretransplant cellular alloimmunity as assessed by a panel of reactive T cells assay correlates with acute renal graft rejectionEmilio D Poggio
Department of Nephrology and Hypertension, Transplant Center, Cleveland Clinic, Cleveland, OH 44195, USA
Transplantation 83:847-52. 2007....
Donor factors influencing graft outcomes in live donor kidney transplantationNaim Issa
Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH 44195, USA
Transplantation 83:593-9. 2007..01). In conclusion, our data suggest that routine assessment of living donor parameters could supplement the consideration of recipient characteristics in predicting posttransplant risk of graft injury/dysfunction...
Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidatesEmilio D Poggio
Department of Nephrology and Hypertension, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
J Am Soc Nephrol 17:564-72. 2006..Preliminary correlations with posttransplantation outcome in seven recipients suggest that PRT screening has the potential to aid in risk assessment in renal transplant candidates...
Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantationBrian R Stephany
Department of Nephrology and Hypertension, Cleveland Clinic Foundation, OH 44195, USA
Transplantation 82:368-74. 2006..Nevertheless, the long-term implications of these findings need to be determined...
Absence of proteinuria predicts improvement in renal function after conversion to sirolimus-based immunosuppressive regimens in lung transplant survivors with chronic kidney diseaseBrian R Stephany
Department of Nephrology and Hypertension, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Heart Lung Transplant 28:564-71. 2009..However, not all patients have such a positive response. We sought to investigate independent predictors of a favorable renal response in a cohort of lung transplant recipients...
Estimating glomerular filtration rate in kidney donors: a model constructed with renal volume measurements from donor CT scansBrian R Herts
Imaging Institute, Cleveland Clinic, 9500 Euclid Ave, Desk Hb6, Cleveland, OH 44195, USA
Radiology 252:109-16. 2009....
Effects of influenza immunization on humoral and cellular alloreactivity in humansLara Danziger-Isakov
Department of Pediatrics, Cleveland Clinic, Cleveland, OH, USA
Transplantation 89:838-44. 2010..To test whether vaccination impacts human alloimmunity, we analyzed humoral and cellular immune reactivity in subjects undergoing influenza vaccination...
Hidden selection bias deriving from donor organ characteristics does not affect performance evaluations of kidney transplant centersJesse D Schold
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Med Care 48:907-14. 2010..An unresolved question is whether centers accepting higher-risk donations are placed in jeopardy for lower evaluations independent of actual quality of care...
An emerging population: kidney transplant candidates who are placed on the waiting list after liver, heart, and lung transplantationTitte R Srinivas
Department of Nephrology and Hypertension, Glickman Urologic and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue Q7, Cleveland, OH 44195, USA
Clin J Am Soc Nephrol 5:1881-6. 2010..ESRD has an adverse impact on patients who have had previous nonrenal solid-organ transplants (NRTxs; liver, heart, lung) and may be referred for a kidney transplant (KTx)...
Implications of the CKD-EPI GFR estimation equation in clinical practiceJesse D Schold
Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA
Clin J Am Soc Nephrol 6:497-504. 2011..CKD-EPI demonstrated superior performance compared with the existing MDRD equation but has not been applied to a healthcare system...
Alloreactivity in renal transplant recipients with and without chronic allograft nephropathyEmilio D Poggio
Department of Immunology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Am Soc Nephrol 15:1952-60. 2004..Immune monitoring to predict long-term outcome should include multiple measures of cellular and humoral immunity...
Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spotsJoshua J Augustine
Division of Nephrology and Hypertension, University Hospitals Case Medical Center, Cleveland, OH, USA
Transplantation 86:529-34. 2008....
Interpreting the estimated glomerular filtration rate in primary care: benefits and pitfallsJames Simon
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, OH 44195, USA
Cleve Clin J Med 78:189-95. 2011..Therefore, it is important that health care professionals understand how to interpret the estimated GFR value and how to recognize when the estimate may not be accurate...
Performance of the modification of diet in renal disease and Cockcroft-Gault equations in the estimation of GFR in health and in chronic kidney diseaseEmilio D Poggio
Department of Nephrology and Hypertension, The Cleveland Clinic Foundation, A51, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Am Soc Nephrol 16:459-66. 2005..This study also emphasizes the complexity of laboratory calibration of serum creatinine measurements, a determining factor when estimating GFR in both healthy individuals and CKD patients with preserved GFR...
The management of renal artery atherosclerosis for renal salvage: does stenting help?Vikram S Kashyap
Department of Vascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Vasc Surg 45:101-8; discussion 108-9. 2007..The purpose of this study was to review the outcomes and durability of percutaneous transluminal angioplasty and stenting (PTA/S) for patients with RAS and decreasing renal function...
Hemodialysis vintage, black ethnicity, and pretransplantation antidonor cellular immunity in kidney transplant recipientsJoshua J Augustine
Division of Nephrology and Hypertension, Case Medical Center, 11100 Euclid Avenue, 1817 Mather, Cleveland, OH 44106, USA
J Am Soc Nephrol 18:1602-6. 2007..Longer HD vintage may also explain the increased T cell alloreactivity that previously was observed in black kidney recipients...
Evaluation of creatinine-based estimates of glomerular filtration rate in a large cohort of living kidney donorsNaim Issa
Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH 44195, USA
Transplantation 86:223-30. 2008..However, among transplant centers donor kidney function evaluation varies widely...
Identifying outpatients with renal insufficiency before contrast-enhanced CT by using estimated glomerular filtration rates versus serum creatinine levelsBrian R Herts
Division of Radiology, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
Radiology 248:106-13. 2008....
Glomerular filtration rate slopes have significantly improved among renal transplants in the United StatesTitte R Srinivas
Department of Nephrology and Hypertension, Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Transplantation 90:1499-505. 2010..In recent years, the use of higher risk donor organs and steroid avoidance regimens with potential increased acute rejection risk have increased. We hypothesized that these patterns adversely affect changes in posttransplant renal function...
Heterogeneous alterations in human alloimmunity associated with immunizationMeagan Roddy
Department of Immunology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Transplantation 80:297-302. 2005..The results suggest that serial immune monitoring of alloreactivity might be beneficial when immunizations are administered to potential transplant recipients...
Performance of the chronic kidney disease-epidemiology study equations for estimating glomerular filtration rate before and after nephrectomyBrian R Lane
Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Urol 183:896-901. 2010..We compared the estimated glomerular filtration rate using several serum creatinine based formulas against the measured rate based on (125)I-iothalamate clearance to determine which most accurately reflects the rate in this setting...
Renal function assessment in the era of chronic kidney disease: renewed emphasis on renal function centered patient careBrian R Lane
Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Urol 182:435-43; discussion 443-4. 2009....
Nephrogenic systemic fibrosis and its association with gadolinium exposure during MRINaim Issa
Department of Nephrology and Hypertension, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 75:95-7, 103-4, 106 passim. 2008..NSF can be very debilitating and can lead to serious complications and death. Health care providers should exercise caution when considering the use of gadolinium-based imaging studies in patients with renal dysfunction...
Living donor kidney transplantation: an update on evaluation and medical implications of donationJ J Taliercio
Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Minerva Urol Nefrol 63:73-87. 2011..However, living kidney donation is the best treatment option available for patients with end stage renal disease and it is a safe procedure for the donor after careful medical consideration in each particular case is given...
Analysis of immune markers in human cardiac allograft recipients and association with coronary artery vasculopathyEmilio D Poggio
Department of Immunology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Heart Lung Transplant 24:1606-13. 2005..Serial assessments of anti-donor immunity using different methods will be required to detect and possibly predict outcome in cardiac transplant recipients...
Factors predicting renal functional outcome after partial nephrectomyBrian R Lane
Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Urol 180:2363-8; discussion 2368-9. 2008..We evaluate independent factors predicting functional outcomes after partial nephrectomy...
Research Grants
- Alloreactive T Cell Immunity in Human Transplant CandidatesEmilio Poggio; Fiscal Year: 2007....
