E P Pioro

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. pmc Motor neuronopathy with dropped hands and downbeat nystagmus: a distinctive disorder? A case report
    Nimish J Thakore
    Department of Neurology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA
    BMC Neurol 6:3. 2006
  2. doi request reprint Current concepts in the pharmacotherapy of pseudobulbar affect
    Erik P Pioro
    Cleveland Clinic, OH 44195, USA
    Drugs 71:1193-207. 2011
  3. doi request reprint Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect
    Erik P Pioro
    Section of ALS and Related Disorders, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Ann Neurol 68:693-702. 2010
  4. ncbi request reprint 1H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla
    E P Pioro
    Department of Neurology and Neurosciences, The Cleveland Clinic Foundation, OH 44195, USA
    Neurology 53:71-9. 1999
  5. ncbi request reprint Proton magnetic resonance spectroscopy (1H-MRS) in ALS
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, Ohio 44195, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 1:S7-16. 2000
  6. ncbi request reprint Neuronal pathology in the wobbler mouse brain revealed by in vivo proton magnetic resonance spectroscopy and immunocytochemistry
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    Neuroreport 9:3041-6. 1998
  7. ncbi request reprint Role of brain-derived neurotrophic factor in wobbler mouse motor neuron disease
    K Tsuzaka
    Department of Neurology and Neurosciences, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Muscle Nerve 24:474-80. 2001
  8. ncbi request reprint Effects of cardiotrophin-1 (CT-1) in a mouse motor neuron disease
    H Mitsumoto
    Department of Neurology and Neurosciences, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Muscle Nerve 24:769-77. 2001
  9. ncbi request reprint MR spectroscopy in amyotrophic lateral sclerosis/motor neuron disease
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    J Neurol Sci 152:S49-53. 1997
  10. ncbi request reprint Development, analysis, refinement, and utility of an interdisciplinary amyotrophic lateral sclerosis database
    V Dal Bello-Haas
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 2:39-46. 2001

Detail Information

Publications11

  1. pmc Motor neuronopathy with dropped hands and downbeat nystagmus: a distinctive disorder? A case report
    Nimish J Thakore
    Department of Neurology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA
    BMC Neurol 6:3. 2006
    ..We report clinical and oculomotor findings in three patients with motor neuronopathy and downbeat nystagmus, a classic sign of vestibulocerebellar disease...
  2. doi request reprint Current concepts in the pharmacotherapy of pseudobulbar affect
    Erik P Pioro
    Cleveland Clinic, OH 44195, USA
    Drugs 71:1193-207. 2011
    ....
  3. doi request reprint Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect
    Erik P Pioro
    Section of ALS and Related Disorders, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Ann Neurol 68:693-702. 2010
    ..To evaluate dextromethorphan combined with ultra low-dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS)...
  4. ncbi request reprint 1H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla
    E P Pioro
    Department of Neurology and Neurosciences, The Cleveland Clinic Foundation, OH 44195, USA
    Neurology 53:71-9. 1999
    ....
  5. ncbi request reprint Proton magnetic resonance spectroscopy (1H-MRS) in ALS
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, Ohio 44195, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 1:S7-16. 2000
    ..This review discusses the advantages and limitations of employing 1H-MRS as an investigative tool in the diagnosis of ALS...
  6. ncbi request reprint Neuronal pathology in the wobbler mouse brain revealed by in vivo proton magnetic resonance spectroscopy and immunocytochemistry
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    Neuroreport 9:3041-6. 1998
    ..In vivo IH-MRS and correlative postmortem study of wobbler mouse brain will allow temporal monitoring of neuronal degeneration and responsiveness to neuroprotective pharmacotherapies...
  7. ncbi request reprint Role of brain-derived neurotrophic factor in wobbler mouse motor neuron disease
    K Tsuzaka
    Department of Neurology and Neurosciences, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Muscle Nerve 24:474-80. 2001
    ..Our study indicates that BDNF is important in halting nitric oxide (NO)-mediated motor neuron degeneration, which has potential implications for the treatment of neurodegenerative disorders...
  8. ncbi request reprint Effects of cardiotrophin-1 (CT-1) in a mouse motor neuron disease
    H Mitsumoto
    Department of Neurology and Neurosciences, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Muscle Nerve 24:769-77. 2001
    ..01). We conclude that CT-1 exerts myotrophic effects as well as neurotrophic effects in a mouse model of spontaneous MND, a finding that has potential therapeutic implications for human MND...
  9. ncbi request reprint MR spectroscopy in amyotrophic lateral sclerosis/motor neuron disease
    E P Pioro
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    J Neurol Sci 152:S49-53. 1997
    ....
  10. ncbi request reprint Development, analysis, refinement, and utility of an interdisciplinary amyotrophic lateral sclerosis database
    V Dal Bello-Haas
    Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 2:39-46. 2001
    ..Ongoing refinement will ensure that this HCP-driven ALS database continues to be informative, practical and effective for decision-making and enhancing delivery of care...
  11. ncbi request reprint Genetic transfer of the wobbler gene to a C57BL/6J x NZB hybrid stock: natural history of the motor neuron disease and response to CNTF and BDNF cotreatment
    T Ishiyama
    Department of Neurology, Cleveland Clinic Foundation, Ohio 44195, USA
    Exp Neurol 148:247-55. 1997
    ..Thus, the hybrid B6NZB-wr/wr mice have a more severe clinical phenotype and offer a unique opportunity to study the mechanisms of presymptomatic motor neuron degeneration and the effects of therapeutic agents for human MND...