Udayakumar Navaneethan

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Random biopsies during surveillance colonoscopy increase dysplasia detection in patients with primary sclerosing cholangitis and ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA Electronic address
    J Crohns Colitis 7:974-81. 2013
  2. doi request reprint Temporal trends in colon neoplasms in patients with primary sclerosing cholangitis and ulcerative colitis
    Udayakumar Navaneethan
    Digestive Disease Institute, Department of Gastroenterology, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 6:845-51. 2012
  3. doi request reprint Severity of primary sclerosing cholangitis and its impact on the clinical outcome of Crohn's disease
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 6:674-80. 2012
  4. ncbi request reprint Duration and severity of primary sclerosing cholangitis is not associated with risk of neoplastic changes in the colon in patients with ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio, USA
    Gastrointest Endosc 75:1045-1054.e1. 2012
  5. ncbi request reprint Progressive primary sclerosing cholangitis requiring liver transplantation is associated with reduced need for colectomy in patients with ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin Gastroenterol Hepatol 10:540-6. 2012
  6. ncbi request reprint Severe disease on endoscopy and steroid use increase the risk for bowel perforation during colonoscopy in inflammatory bowel disease patients
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 6:470-5. 2012
  7. doi request reprint Prevalence and risk factors for colonic perforation during colonoscopy in hospitalized inflammatory bowel disease patients
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 5:189-95. 2011
  8. ncbi request reprint Idiopathic hyperammonemia in a patient with total pancreatectomy and islet cell transplantation
    Udayakumar Navaneethan
    Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44118, USA
    JOP 11:620-4. 2010
  9. pmc Clostridium difficile infection and inflammatory bowel disease: understanding the evolving relationship
    Udayakumar Navaneethan
    Victor W Fazio Center for Inflammatory Bowel Disease, Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, The Cleveland Clinic A31, 9500 Euclid Ave, Cleveland, OH 44195, United States
    World J Gastroenterol 16:4892-904. 2010
  10. ncbi request reprint Herpes simplex virus hepatitis - it's high time we consider empiric treatment
    Udayakumar Navaneethan
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, USA
    J Gastrointestin Liver Dis 20:93-6. 2011

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Random biopsies during surveillance colonoscopy increase dysplasia detection in patients with primary sclerosing cholangitis and ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA Electronic address
    J Crohns Colitis 7:974-81. 2013
    ..The role of random vs. target biopsies in these patients has not been investigated. Our aim was to evaluate the yield and clinical impact of random biopsies during surveillance colonoscopies in patients with PSC-UC...
  2. doi request reprint Temporal trends in colon neoplasms in patients with primary sclerosing cholangitis and ulcerative colitis
    Udayakumar Navaneethan
    Digestive Disease Institute, Department of Gastroenterology, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 6:845-51. 2012
    ..It is unclear whether characteristics of colon neoplasia have changed over time. The aim of the study was to examine the temporal trends in colon neoplasia in patients with PSC and UC...
  3. doi request reprint Severity of primary sclerosing cholangitis and its impact on the clinical outcome of Crohn's disease
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 6:674-80. 2012
    ..The aim of the study was to study the association between the severity of PSC and clinical outcome of CD, comparing the course of CD in patients with PSC not needing orthotopic liver transplantation (OLT) and those requiring OLT...
  4. ncbi request reprint Duration and severity of primary sclerosing cholangitis is not associated with risk of neoplastic changes in the colon in patients with ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio, USA
    Gastrointest Endosc 75:1045-1054.e1. 2012
    ..Annual surveillance colonoscopy to detect colon cancer is recommended for patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC). Limited data currently support these recommendations...
  5. ncbi request reprint Progressive primary sclerosing cholangitis requiring liver transplantation is associated with reduced need for colectomy in patients with ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin Gastroenterol Hepatol 10:540-6. 2012
    ..We investigated the association between the severity of primary sclerosing cholangitis (PSC) and clinical outcomes of patients with ulcerative colitis (UC) on the basis of need for colectomy...
  6. ncbi request reprint Severe disease on endoscopy and steroid use increase the risk for bowel perforation during colonoscopy in inflammatory bowel disease patients
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 6:470-5. 2012
    ..Colonoscopic perforation is a rare complication. We sought to determine its risk factors in patients with inflammatory bowel disease (IBD)...
  7. doi request reprint Prevalence and risk factors for colonic perforation during colonoscopy in hospitalized inflammatory bowel disease patients
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 5:189-95. 2011
    ..Colonic perforation is a rare complication associated with colonoscopy. There are no population-based studies on the risk of colonic perforation in IBD inpatients...
  8. ncbi request reprint Idiopathic hyperammonemia in a patient with total pancreatectomy and islet cell transplantation
    Udayakumar Navaneethan
    Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44118, USA
    JOP 11:620-4. 2010
    ..Idiopathic hyperammonemia is characterized by elevated serum ammonia associated with neurological deterioration of no other obvious etiology associated with relatively normal liver function tests and normal amino-acid levels...
  9. pmc Clostridium difficile infection and inflammatory bowel disease: understanding the evolving relationship
    Udayakumar Navaneethan
    Victor W Fazio Center for Inflammatory Bowel Disease, Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, The Cleveland Clinic A31, 9500 Euclid Ave, Cleveland, OH 44195, United States
    World J Gastroenterol 16:4892-904. 2010
    ..For CDI in the setting of underlying IBD, vancomycin appears to be more efficacious than metronidazole. Randomized controlled trials are required to clearly define the appropriate management for CDI in patients with IBD...
  10. ncbi request reprint Herpes simplex virus hepatitis - it's high time we consider empiric treatment
    Udayakumar Navaneethan
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, USA
    J Gastrointestin Liver Dis 20:93-6. 2011
    ..The above results demonstrate a significant impact to fulminant hepatic failure and should prompt clinicians to consider empiric acyclovir therapy for at risk patients...
  11. ncbi request reprint Awareness about clostridium difficile infection among internal medicine residents in the United States
    U Navaneethan
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Minerva Gastroenterol Dietol 57:231-40. 2011
    ..The principal objective of this study was to assess the knowledge and awareness of internal medicine (IM) residents regarding the epidemiology, clinical recognition, diagnosis and management of CDI...
  12. ncbi request reprint Successful diagnosis and management of biliary cast syndrome in a liver transplant patient using single operator cholangioscopy
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    JOP 12:461-3. 2011
    ..Endoscopic techniques are recently described in the successful removal of biliary casts. Peroral single operator cholangioscopy is useful for direct visualization of bile ducts, tissue sampling and therapeutic applications...
  13. doi request reprint Tissue infiltration of IgG4+ plasma cells in symptomatic patients with ileal pouch-anal anastomosis
    Udayakumar Navaneethan
    Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, OH, USA
    J Crohns Colitis 5:570-6. 2011
    ..Inflammatory bowel disease (IBD) is reported to be associated with autoimmune pancreatitis. The aim of the study was to investigate serum IgG4 and tissue infiltration of IgG4+ plasma cells in symptomatic patients with ileal pouches...
  14. ncbi request reprint Delay in performing ERCP and adverse events increase the 30-day readmission risk in patients with acute cholangitis
    Udayakumar Navaneethan
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Gastrointest Endosc 78:81-90. 2013
    ..Readmission to the hospital within 30 days of discharge (30-day readmission rate) is used as a quality measure...
  15. doi request reprint Clostridium difficile infection is associated with worse long term outcome in patients with ulcerative colitis
    Udayakumar Navaneethan
    Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Crohns Colitis 6:330-6. 2012
    ..Clostridium difficile infection (CDI) is becoming prevalent in general population as well as in patients with inflammatory bowel disease (IBD)...
  16. doi request reprint Impact of budesonide on liver function tests and gut inflammation in patients with primary sclerosing cholangitis and ileal pouch anal anastomosis
    Udayakumar Navaneethan
    Departments of Gastroenterology and Colorectal Surgery, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA
    J Crohns Colitis 6:536-42. 2012
    ..This study was designed to evaluate the efficacy of oral budesonide on liver function tests in patients with PSC and pouchitis associated with ileal pouch-anal anastomosis (IPAA)...
  17. ncbi request reprint Progression of low-grade dysplasia to advanced neoplasia based on the location and morphology of dysplasia in ulcerative colitis patients with extensive colitis under colonoscopic surveillance
    Udayakumar Navaneethan
    Department of Gastroenterology Hepatology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 7:e684-91. 2013
    ..The management of low-grade dysplasia (LGD) in ulcerative colitis (UC) patients remains unclear...
  18. doi request reprint Vascular endothelial growth factor levels in bile distinguishes pancreatic cancer from other etiologies of biliary stricture: a pilot study
    Udayakumar Navaneethan
    Section for Advanced Endoscopy and Pancreatobiliary Disorders, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Desk A30, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA
    Dig Dis Sci 58:2986-92. 2013
    ..Determining the benign or malignant nature of biliary strictures can be challenging. Vascular endothelial growth factor (VEGF) plays an important role in tumor angiogenesis...
  19. ncbi request reprint Lipidomic profiling of bile in distinguishing benign from malignant biliary strictures: a single-blinded pilot study
    Udayakumar Navaneethan
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Gastroenterol 109:895-902. 2014
    ..The objective of the study was to investigate whether oxPLs are enriched in the bile of malignant biliary strictures...
  20. ncbi request reprint Natural history of low grade dysplasia in patients with primary sclerosing cholangitis and ulcerative colitis
    Preethi G K Venkatesh
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    J Crohns Colitis 7:968-73. 2013
    ..The aim of this study was to determine the natural history of LGD and its progression to high grade dysplasia (HGD)/colorectal cancer (CRC) in PSC-UC patients...
  21. doi request reprint Impact of inflammatory bowel disease on post-cholecystectomy complications and hospitalization costs: a Nationwide Inpatient Sample study
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 7:e164-70. 2013
    ..The aim of the current population-based study was to verify whether concomitant IBD was indeed associated with an increased risk of post-cholecystectomy complications...
  22. ncbi request reprint Primary sclerosing cholangitis is associated with endoscopic and histologic inflammation of the distal afferent limb in patients with ileal pouch-anal anastomosis
    Bo Shen
    Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Inflamm Bowel Dis 17:1890-900. 2011
    ..The aim of this study was to compare endoscopic and histologic inflammation in the afferent limb (prepouch ileum) and pouch between IPAA patients with and without PSC...
  23. ncbi request reprint Backwash ileitis and the risk of colon neoplasia in ulcerative colitis patients undergoing restorative proctocolectomy
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    Dig Dis Sci 58:2019-27. 2013
    ..The significance of backwash ileitis (BWI) relating to the risk of colon neoplasia in ulcerative colitis (UC) patients is controversial...
  24. doi request reprint Prevalence and risk factors for colonic perforation during colonoscopy in hospitalized end-stage renal disease patients on hemodialysis
    Udayakumar Navaneethan
    Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Int J Colorectal Dis 27:811-6. 2012
    ..We sought to determine nationwide, population-based prevalence in rates of colonic perforation during colonoscopy among ESRD inpatients on HD in the US, and to assess risk factors for colonic perforation in this patient population...
  25. pmc Microscopic colitis: is it a spectrum of inflammatory bowel disease?
    Ramprasad Jegadeesan
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Desk A30, Cleveland Clinic, Cleveland, OH 44195, United States
    World J Gastroenterol 19:4252-6. 2013
    ..Till then it might be prudent to follow up these patients to assess for the relapse of inflammatory bowel disease as well as for dysplasia surveillance. ..
  26. doi request reprint Elevated immunoglobulin G4 level is associated with reduced colectomy-free survival in patients with primary sclerosing cholangitis and ulcerative colitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Crohns Colitis 7:e35-41. 2013
    ..The aim of the study was to investigate the clinical outcomes of PSC and UC in patients with elevated serum IgG4...
  27. doi request reprint Impact of ileal pouch-anal anastomosis on the surgical outcome of orthotopic liver transplantation for primary sclerosing cholangitis
    Emmanuel C Obusez
    Lerner College of Medicine, Department of Gastroenterology and Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    J Crohns Colitis 7:230-8. 2013
    ..While studies to date show that OLT may impact the outcome of IPAA, the effect of IPAA on the surgical outcome of OLT is not known...
  28. doi request reprint Presence of concomitant inflammatory bowel disease is associated with an increased risk of postcholecystectomy complications
    Udayakumar Navaneethan
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Inflamm Bowel Dis 18:1682-8. 2012
    ..Surgery in patients with inflammatory bowel disease (IBD) is often associated with complications. The aim of our study was to evaluate whether concomitant IBD was associated with an increased risk of postcholecystectomy complications...
  29. doi request reprint Influence of ileal pouch anal anastomosis on bone loss in ulcerative colitis patients
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 5:415-22. 2011
    ..It is unclear whether proctocolectomy with ileal pouch-anal anastomosis (IPAA) for UC alters the risk of bone loss. The aim of this study was to compare BMD in UC patients with and without IPAA...
  30. doi request reprint Elevated serum IgG4 is associated with chronic antibiotic-refractory pouchitis
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Gastrointest Surg 15:1556-61. 2011
    ..The aims of the study were to investigate the prevalence of elevated serum IgG4 in symptomatic patients with ileal pouches and to characterize clinical features of pouch disorders in these patients...
  31. doi request reprint Increased serum levels of carbohydrate antigen 19-9 and outcomes in primary sclerosing cholangitis patients without cholangiocarcinoma
    Preethi G K Venkatesh
    Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Dig Dis Sci 58:850-7. 2013
    ..Carbohydrate antigen 19-9 (CA 19-9) is the serum marker used to diagnose cholangiocarcinoma (CCA) in patients with primary sclerosing cholangitis (PSC)...
  32. doi request reprint Impact of Clostridium difficile infection in patients with ulcerative colitis
    Revital Kariv
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Crohns Colitis 5:34-40. 2011
    ..Clostridium difficile infection (CDI) is becoming prevalent in general population as well as in patients with inflammatory bowel disease (IBD)...
  33. doi request reprint Prevalence and clinical implications of positive serum anti-microsomal antibodies in symptomatic patients with ileal pouches
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Gastrointest Surg 15:1577-82. 2011
    ..The aims of the study were to investigate the prevalence of positive anti-microsomal antibody in symptomatic patients with ileal pouches and to investigate its clinical implications...
  34. ncbi request reprint Secondary pouchitis: those with identifiable etiopathogenetic or triggering factors
    Udayakumar Navaneethan
    The Pouchitis Clinic, Digestive Disease Institute, The Cleveland Clinic Foundation, Ohio 44195, USA
    Am J Gastroenterol 105:51-64. 2010
    ..Careful evaluation of these secondary causes of pouchitis that may contribute to resistance to antibiotics should be performed before the introduction of next-line medical therapy...
  35. doi request reprint Current controversies in fluid resuscitation in acute pancreatitis: a systematic review
    Guru Trikudanathan
    Department of Internal Medicine, University of Connecticut Medical Center, Farmington, CT, USA
    Pancreas 41:827-34. 2012
    ..Crystalloids are the currently recommended fluids for management of these patients. Current studies are underway to determine the optimal end points of fluid resuscitation that determine outcome...
  36. doi request reprint Hepatobiliary disorders and complications of inflammatory bowel disease
    Preethi Gk Venkatesh
    Department of Gastroenterology Hepatology, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Dig Dis 12:245-56. 2011
    ..Interdisciplinary approach, involving gastroenterologists, hepatologists and, in advanced cases, general, colorectal, and liver transplant surgeons, is advocated...
  37. doi request reprint Diagnostic and therapeutic yield is not influenced by the timing of small-bowel enteroscopy: morning versus afternoon
    Madhusudhan R Sanaka
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Gastrointest Endosc 77:62-70. 2013
    ..Small-bowel enteroscopies (BEs) are tedious and prolonged, and their efficacy may be affected by the timing of procedures...
  38. doi request reprint Diagnosis and therapeutic management of extra-intestinal manifestations of inflammatory bowel disease
    Guru Trikudanathan
    Department of Internal Medicine, University of Connecticut Medical Center, Farmington, CT, USA
    Drugs 72:2333-49. 2012
    ..Future research targeting the pathogenesis, early diagnosis and treatment of these EIMs is required...
  39. doi request reprint Utility of fecal and serum anti-Saccharomyces cerevisiae antibodies in the diagnosis of Crohn's disease-like condition of the pouch
    Linda Y Tang
    Pouchitis Clinic, Digestive Disease Institute A31, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Int J Colorectal Dis 27:1455-63. 2012
    ....
  40. doi request reprint Laboratory tests for patients with ileal pouch-anal anastomosis: clinical utility in predicting, diagnosing, and monitoring pouch disorders
    Udayakumar Navaneethan
    The Pouchitis Clinic, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Gastroenterol 104:2606-15. 2009
    ....
  41. doi request reprint IgG4-associated ampullitis and cholangiopathy in Crohn's disease
    Udayakumar Navaneethan
    Department of Gastroenterology Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 5:451-6. 2011
    ..His serum IgG4 was 164 mg/dL. The association of IgG4-expressing plasma cell accumulation in the gastrointestinal tract with IBD in patients with hepatobiliary manifestation may have pathogenetic, diagnostic and therapeutic implications...
  42. doi request reprint Cytomegalovirus ileitis in a patient after liver transplantation-differentiating from de novo IBD
    Udayakumar Navaneethan
    Department of Internal Medicine, University of Cincinnati College of Medicine, OH, USA
    J Crohns Colitis 5:354-9. 2011
    ..De novo IBD should be considered in the differential diagnosis in these patients who do not improve with anti-viral treatment...
  43. ncbi request reprint Fluorescence in situ hybridization for diagnosis of cholangiocarcinoma in primary sclerosing cholangitis: a systematic review and meta-analysis
    Udayakumar Navaneethan
    Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio
    Gastrointest Endosc 79:943-950.e3. 2014
    ..Patients with primary sclerosing cholangitis (PSC) are at risk of developing cholangiocarcinoma (CCA). Fluorescence in situ hybridization (FISH) may aid diagnosis of CCA...
  44. ncbi request reprint Predictors for detection of cancer in patients with indeterminate biliary stricture and atypical cells on endoscopic retrograde brush cytology
    Udayakumar Navaneethan
    Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA
    J Dig Dis 15:268-75. 2014
    ..This study aimed to investigate the detection of cancer (pancreatic and biliary carcinoma) in patients with atypical cells on ERBC and the factors predicting it...
  45. ncbi request reprint Diagnostic yield of bile duct brushings for cholangiocarcinoma in primary sclerosing cholangitis: a systematic review and meta-analysis
    Guru Trikudanathan
    Department of Gastroenterology, University of Minnesota, Minneapolis, Minnesota, USA
    Gastrointest Endosc 79:783-9. 2014
    ..The most ominous adverse event of primary sclerosing cholangitis (PSC) is development of cholangiocarcinoma (CCA). There is a wide variation in the reported diagnostic yield of bile duct brush cytology in PSC strictures...
  46. doi request reprint Increased mortality with peptic ulcer bleeding in patients with both compensated and decompensated cirrhosis
    Preethi G K Venkatesh
    Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio, USA
    Gastrointest Endosc 79:605-14.e3. 2014
    ..Cirrhosis is associated with worse outcomes in peptic ulcer bleeding (PUB). There are no population-based studies from the United States on the impact of cirrhosis on PUB outcomes...
  47. doi request reprint De novo inflammatory bowel disease and its mimics after organ transplantation
    Sansrita Nepal
    Department of Gastroenterology Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Inflamm Bowel Dis 19:1518-27. 2013
    ..In this article, we discuss the epidemiology, clinical features, and outcomes of de novo IBD after transplantation and highlight their differences in presentation, diagnosis, and management...
  48. ncbi request reprint Pros and cons of antibiotic therapy for pouchitis
    Udayakumar Navaneethan
    The Pouchitis Clinic, Digestive Disease Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Expert Rev Gastroenterol Hepatol 3:547-59. 2009
    ..The risks and benefits should be carefully balanced in patients who require long-term antibiotic therapy, and safe, efficacious, non-antibiotic-based agents are needed...
  49. doi request reprint Isospora belli superinfection in a patient with eosinophilic gastroenteritis--a diagnostic challenge
    Udayakumar Navaneethan
    Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Crohns Colitis 6:236-9. 2012
    ....
  50. doi request reprint Hepatopancreatobiliary manifestations and complications associated with inflammatory bowel disease
    Udayakumar Navaneethan
    Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Inflamm Bowel Dis 16:1598-619. 2010
    ..An interdisciplinary approach, involving gastroenterologists, hepatologists, and, in advanced cases, general, colorectal, and transplant surgeons is advocated...
  51. doi request reprint Intraductal papillary mucinous neoplasm and acute pancreatitis
    Preethi G K Venkatesh
    Digestive Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    J Clin Gastroenterol 45:755-8. 2011
    ..Future longitudinal and prospective studies to understand the natural history of AP in patients with IPMN are required to better manage patients with recurrent AP in the setting of IPMN...
  52. doi request reprint Diagnosis and management of pouchitis and ileoanal pouch dysfunction
    Udayakumar Navaneethan
    The Pouchitis Clinic, Digestive Disease Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Curr Gastroenterol Rep 12:485-94. 2010
    ..Although management of antibiotic-dependent or antibiotic-refractory pouchitis has been challenging, secondary etiology for pouchitis should be evaluated and modified, if possible...
  53. ncbi request reprint Risk of comorbidities and outcomes in patients with lower gastrointestinal bleeding-a nationwide study
    Preethi G K Venkatesh
    Digestive Disease Institute, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA
    Int J Colorectal Dis 29:953-60. 2014
    ..The impact of comorbidities on outcomes of patients with lower gastrointestinal bleeding (LGIB) remains unknown...
  54. doi request reprint Risk factors for abnormal liver function tests in patients with ileal pouch-anal anastomosis for underlying inflammatory bowel disease
    Udayakumar Navaneethan
    The Pouchitis Clinic, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Gastroenterol 104:2467-75. 2009
    ..The aim of this study was to evaluate the prevalence and to identify risk factors for abnormal LFTs in patients with IPAA and underlying IBD...
  55. ncbi request reprint Endoscopic resection of large sporadic non-ampullary duodenal polyps: efficacy and long-term recurrence
    Udayakumar Navaneethan
    Digestive Disease Institute Desk Q3, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA
    Surg Endosc 28:2616-22. 2014
    ..There are limited data on the safety, efficacy, and long-term recurrence data after endoscopic resection of sporadic, non-ampullary, and large duodenal polyps...
  56. pmc Endoscopic management of difficult common bile duct stones
    Guru Trikudanathan
    Department of Internal Medicine, University of Connecticut Medical Center, Farmington, CT 06269, United States
    World J Gastroenterol 19:165-73. 2013
    ..Biliary stenting may be an alternative treatment option for frail and elderly patients or those with serious co morbidities...
  57. doi request reprint Timing of colonoscopy and outcomes in patients with lower GI bleeding: a nationwide population-based study
    Udayakumar Navaneethan
    Digestive Disease Institute, The Cleveland Clinic, Cleveland, Ohio
    Gastrointest Endosc 79:297-306.e12. 2014
    ..The role of urgent colonoscopy in lower GI bleeding (LGIB) remains controversial. Population-based studies on LGIB outcomes are lacking...
  58. ncbi request reprint Outcome of esophageal carcinoma in the veteran affairs population: a comparative analysis from the Veteran Affairs Central Cancer Registry
    Muhammad Shaalan Beg
    Department of Internal Medicine, Division of Hematology and Medical Oncology, University of Cincinnati and Cincinnati VA Medical Center, Cincinnati, OH 45267, USA
    Am J Clin Oncol 32:286-90. 2009
    ..However, data on esophageal carcinoma in the Veteran Affairs (VA) population is lacking. We set to describe site-specific and histology-specific characteristics of esophageal cancer in the VA population over the past decades...
  59. doi request reprint Modern treatment of patients with chronic pancreatitis
    Guru Trikudanathan
    Department of Internal Medicine, University of Connecticut Medical Center, Farmington, CT, USA
    Gastroenterol Clin North Am 41:63-76. 2012
    ..Newer therapeutic targets that will transcend the management of CP beyond just pain control and enzyme supplementation are required in the future...
  60. doi request reprint An LC-ESI-MS method for the quantitative analysis of bile acids composition in fecal materials
    Xiaohan Cai
    Department of Chemistry, Cleveland State University, Cleveland, OH 44115, USA
    Biomed Chromatogr 26:101-8. 2012
    ..05-5 µmol/L. This SA-IS method was successfully applied to the analysis of bile acids in the samples collected from patients diagnosed with inflammatory bowel disease...
  61. doi request reprint Infectious colitis
    Udayakumar Navaneethan
    Division of Digestive Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Curr Opin Gastroenterol 27:66-71. 2011
    ....
  62. doi request reprint Antegrade is more effective than retrograde enteroscopy for evaluation and management of suspected small-bowel disease
    Madhusudhan R Sanaka
    Department of Gastroenterology, Digestive Disease Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Clin Gastroenterol Hepatol 10:910-6. 2012
    ..Antegrade and retrograde enteroscopy are useful for evaluating the proximal and distal small bowel, respectively. We compared the diagnostic yield, therapeutic yield, and complications of antegrade and retrograde enteroscopy...
  63. pmc Predicting the probable outcome of treatment in HCV patients
    Udayakumar Navaneethan
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Therap Adv Gastroenterol 2:287-302. 2009
    ..Future studies on the factors that predict treatment response and tailoring treatment based on this is required if we are to conquer this disease...
  64. pmc Pros and cons of medical management of ulcerative colitis
    Udayakumar Navaneethan
    Center for Inflammatory Bowel Disease, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio
    Clin Colon Rectal Surg 23:227-38. 2010
    ..In addition, there is always a concern about patients' compliance to medical therapy, cost of medications, and risk for UC-associated dysplasia. The authors discuss the pros and cons of medications used in the treatment of UC...
  65. doi request reprint Intra-abdominal fungal infections complicating acute pancreatitis: a review
    Guru Trikudanathan
    Department of Internal Medicine, University of Connecticut Medical Center, Farmington, Connecticut, USA
    Am J Gastroenterol 106:1188-92. 2011
    ..Although antifungal prophylaxis has been suggested for patients on broad-spectrum antibiotics, no randomized controlled trials have yet studied its efficacy in preventing PFI...
  66. pmc Hepatitis E and pregnancy: understanding the pathogenesis
    Udayakumar Navaneethan
    Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA
    Liver Int 28:1190-9. 2008
    ..Further research in the immunology of HEV and pregnancy is required to conquer this disease in the near future...
  67. ncbi request reprint Azathioprine induced pancreatitis in a patient with co-existing autoimmune pancreatitis and hepatitis
    Preethi G K Venkatesh
    Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
    JOP 12:250-4. 2011
    ..The risk of azathioprine use in patients with underlying disease of pancreas including autoimmune pancreatitis is unclear...