Sankar D Navaneethan

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Adiposity measures, lean body mass, physical activity and mortality: NHANES 1999-2004
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue Q7, Cleveland, OH 44195, USA
    BMC Nephrol 15:108. 2014
  2. pmc Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study
    L Ebony Boulware
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, 2024 E, Monument Street, Baltimore, MD 21205, USA
    BMC Nephrol 13:167. 2012
  3. pmc Metabolic syndrome, ESRD, and death in CKD
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin J Am Soc Nephrol 8:945-52. 2013
  4. pmc Electronic health records: a new tool to combat chronic kidney disease?
    Sankar D Navaneethan
    Department of Neprology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Clin Nephrol 79:175-83. 2013
  5. pmc Overweight, obesity and intentional weight loss in chronic kidney disease: NHANES 1999-2006
    S D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Int J Obes (Lond) 36:1585-90. 2012
  6. pmc Obesity, anthropometric measures and chronic kidney disease complications
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Am J Nephrol 36:219-27. 2012
  7. pmc Serum triglycerides and risk for death in Stage 3 and Stage 4 chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA
    Nephrol Dial Transplant 27:3228-34. 2012
  8. pmc Serum bicarbonate and mortality in stage 3 and stage 4 chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology, Hypertension, Glickman Urological and Kidney Institute, and Cleveland Clinic Lerner College of Medicine of CWRU, Cleveland, OH 44195, USA
    Clin J Am Soc Nephrol 6:2395-402. 2011
  9. pmc Low 25-hydroxyvitamin D levels and mortality in non-dialysis-dependent CKD
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland, OH 44195, USA
    Am J Kidney Dis 58:536-43. 2011
  10. ncbi request reprint Treatment options for proliferative lupus nephritis: an update of clinical trial evidence
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Drugs 68:2095-104. 2008

Detail Information

Publications40

  1. ncbi request reprint Adiposity measures, lean body mass, physical activity and mortality: NHANES 1999-2004
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue Q7, Cleveland, OH 44195, USA
    BMC Nephrol 15:108. 2014
    ..We studied the associations between measures of adiposity, lean body mass, leisure time physical activity (LTPA), and death in those with and without chronic kidney disease (CKD)...
  2. pmc Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study
    L Ebony Boulware
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, 2024 E, Monument Street, Baltimore, MD 21205, USA
    BMC Nephrol 13:167. 2012
    ..Evidence is lacking to inform providers' and patients' decisions about many common treatment strategies for patients with end stage renal disease (ESRD)...
  3. pmc Metabolic syndrome, ESRD, and death in CKD
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin J Am Soc Nephrol 8:945-52. 2013
    ..This study examined the associations between metabolic syndrome and its components with ESRD and death among those patients with stages 3 and 4 CKD (estimated GFR=15-59 ml/min per 1.73 m(2))...
  4. pmc Electronic health records: a new tool to combat chronic kidney disease?
    Sankar D Navaneethan
    Department of Neprology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Clin Nephrol 79:175-83. 2013
    ..Thus, future studies should explore the optimal methods of using EHRs to improve CKD care and research at the individual patient level, health system and population levels...
  5. pmc Overweight, obesity and intentional weight loss in chronic kidney disease: NHANES 1999-2006
    S D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Int J Obes (Lond) 36:1585-90. 2012
    ..We aimed to examine: (a) lifestyle and behavioral factors, (b) factors related to pursuing weight loss and (c) weight loss modalities pursued by CKD and non-CKD individuals who are overweight and obese...
  6. pmc Obesity, anthropometric measures and chronic kidney disease complications
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Am J Nephrol 36:219-27. 2012
    ..We examined the associations of BMI and WC with various CKD complications...
  7. pmc Serum triglycerides and risk for death in Stage 3 and Stage 4 chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA
    Nephrol Dial Transplant 27:3228-34. 2012
    ..The associations between serum triglyceride and all-cause mortality among patients with chronic kidney disease (CKD) are unclear...
  8. pmc Serum bicarbonate and mortality in stage 3 and stage 4 chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology, Hypertension, Glickman Urological and Kidney Institute, and Cleveland Clinic Lerner College of Medicine of CWRU, Cleveland, OH 44195, USA
    Clin J Am Soc Nephrol 6:2395-402. 2011
    ..We studied the associations of both low and high serum bicarbonate levels with all-cause mortality among stage 3 and 4 chronic kidney disease (CKD) patients...
  9. pmc Low 25-hydroxyvitamin D levels and mortality in non-dialysis-dependent CKD
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland, OH 44195, USA
    Am J Kidney Dis 58:536-43. 2011
    ..Low 25-hydroxyvitamin D (25[OH]D) levels are common in patients with non-dialysis-dependent chronic kidney disease (CKD). The associations between low 25(OH)D levels and mortality in non-dialysis-dependent patients with CKD are unclear...
  10. ncbi request reprint Treatment options for proliferative lupus nephritis: an update of clinical trial evidence
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Drugs 68:2095-104. 2008
    ..Ongoing clinical trials will provide further evidence...
  11. pmc Development and validation of an electronic health record-based chronic kidney disease registry
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, 9500 Euclid Avenue, Q7, Cleveland Clinic, Cleveland, OH 44195, USA
    Clin J Am Soc Nephrol 6:40-9. 2011
    ..We developed an electronic health record (EHR)-based CKD registry at the Cleveland Clinic and validated comorbid conditions...
  12. ncbi request reprint Referral patterns of primary care physicians for chronic kidney disease in general population and geriatric patients
    S D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44122, USA
    Clin Nephrol 73:260-7. 2010
    ..We sought to assess factors influencing PCPs referral patterns in the general population and in geriatric patients, and compared their perceptions to the referral patterns...
  13. pmc Aldosterone antagonists for preventing the progression of chronic kidney disease: a systematic review and meta-analysis
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin J Am Soc Nephrol 4:542-51. 2009
    ..We evaluated the benefits and harms of adding selective and nonselective AA in CKD patients already on RAS...
  14. doi request reprint Bariatric surgery and progression of chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Surg Obes Relat Dis 5:662-5. 2009
    ..Obesity is an independent predictor for the development and progression of chronic kidney disease (CKD). The effect of weight reduction on the progression of kidney disease in patients with pre-existing CKD is unclear...
  15. doi request reprint Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Ave, Q7, Cleveland, OH 44122, USA
    Am J Kidney Dis 54:619-37. 2009
    ..Phosphate binders are widely used to control serum phosphorus levels in patients with chronic kidney disease (CKD). We analyzed the effects of phosphate binders on biochemical and patient-level end points in patients with CKD...
  16. pmc Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin J Am Soc Nephrol 4:1565-74. 2009
    ..We conducted a systematic review to assess the benefits of intentional weight loss in patients with non-dialysis-dependent CKD and glomerular hyperfiltration...
  17. doi request reprint Metabolic syndrome and mild to moderate chronic kidney disease among minorities
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Semin Nephrol 30:51-8. 2010
    ..We present an integrated pathophysiologic viewpoint that incorporates insights from basic science, socioeconomic inquiry, and clinical studies into a framework for clinical practice and investigation...
  18. pmc Urinary albumin excretion, HMW adiponectin, and insulin sensitivity in type 2 diabetic patients undergoing bariatric surgery
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Ave, Q7, Cleveland, OH 44195, USA
    Obes Surg 20:308-15. 2010
    ..In this pilot study, we determined the effect of weight loss induced by different types of bariatric surgery on albuminuria in severely obese type 2 diabetic (T2DM) subjects...
  19. ncbi request reprint Anti-neutrophil cytoplasmic antibody associated crescentic IgA nephropathy in hematopoietic stem cell transplantation
    S D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland OH 44195, USA
    Clin Nephrol 71:59-62. 2009
    ..The etiology of IgA nephropathy developing after hematopoietic stem cell transplantation is unclear and larger registry-based studies are needed to further explore this condition...
  20. doi request reprint Sodium bicarbonate therapy for prevention of contrast-induced nephropathy: a systematic review and meta-analysis
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH 44195, USA
    Am J Kidney Dis 53:617-27. 2009
    ..Optimal hydration measures to prevent contrast-induced nephropathy are controversial...
  21. pmc Implications of the CKD-EPI GFR estimation equation in clinical practice
    Jesse D Schold
    Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA
    Clin J Am Soc Nephrol 6:497-504. 2011
    ..CKD-EPI demonstrated superior performance compared with the existing MDRD equation but has not been applied to a healthcare system...
  22. pmc Metabolic syndrome and kidney disease: a systematic review and meta-analysis
    George Thomas
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Clin J Am Soc Nephrol 6:2364-73. 2011
    ..Risk estimates for eGFR <60 ml/min per 1.73 m(2) were extracted from individual studies and pooled using a random effects model. The results for proteinuria outcomes were not pooled because of the small number of studies...
  23. doi request reprint Nontraumatic subarachnoid hemorrhage in maintenance dialysis hospitalizations: trends and outcomes
    Ankit Sakhuja
    From the Departments of Nephrology and Hypertension A S, J D S, S D N, Quantitative Health Sciences J D S, and Neurology I K, Cleveland Clinic, Cleveland, OH and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee G K
    Stroke 45:71-6. 2014
    ..However, the outcomes of patients on maintenance dialysis with SAH are not well known. This study was designed to look at incidence and outcomes of SAH in those on maintenance dialysis...
  24. doi request reprint 2009 influenza A infection and acute kidney injury: incidence, risk factors, and complications
    Sevag G Demirjian
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Am J Nephrol 34:1-8. 2011
    ..Respiratory complications and renal failure have been the leading causes for hospitalization and critical illness. We describe the risk factors and complications of acute kidney injury (AKI) in patients with influenza A...
  25. pmc Vitamin D supplementation in chronic kidney disease: a systematic review and meta-analysis of observational studies and randomized controlled trials
    Praveen Kandula
    Department of Nephrology, Indiana University, Indianapolis, Indiana, USA
    Clin J Am Soc Nephrol 6:50-62. 2011
    ..The benefits and harms of vitamin D supplementation (ergocalciferol or cholecalciferol) were assessed in patients with nondialysis-dependent CKD, dialysis-dependent CKD, and renal transplant recipients...
  26. pmc Chronic kidney disease in an electronic health record problem list: quality of care, ESRD, and mortality
    Stacey E Jolly
    Department of General Internal Medicine, Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Nephrol 39:288-96. 2014
    ..Whether chronic kidney disease (CKD) recognition in an electronic health record (EHR) problem list improves processes of care or clinical outcomes of end-stage renal disease (ESRD) and death is unclear...
  27. pmc Prognostic importance of serum alkaline phosphatase in CKD stages 3-4 in a clinical population
    Jonathan J Taliercio
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH
    Am J Kidney Dis 62:703-10. 2013
    ..Elevated total serum alkaline phosphatase (ALP) levels have been associated with mortality in the general population and in dialysis patients...
  28. doi request reprint Prevalence and correlates of self-reported sexual dysfunction in CKD: a meta-analysis of observational studies
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA
    Am J Kidney Dis 56:670-85. 2010
    ..Sexual dysfunction is an under-recognized problem in men and women with chronic kidney disease (CKD). The prevalence, correlates, and predictors of this condition in patients with CKD have not been evaluated comprehensively...
  29. doi request reprint Glomerular filtration rate slopes have significantly improved among renal transplants in the United States
    Titte R Srinivas
    Department of Nephrology and Hypertension, Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Transplantation 90:1499-505. 2010
    ..In recent years, the use of higher risk donor organs and steroid avoidance regimens with potential increased acute rejection risk have increased. We hypothesized that these patterns adversely affect changes in posttransplant renal function...
  30. doi request reprint Effects of bariatric surgery on diabetic nephropathy after 5 years of follow-up
    Helen M Heneghan
    Bariatric and Metabolic Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Surg Obes Relat Dis 9:7-14. 2013
    ..We hypothesized that improving diabetes control may have positive effects on end-organ complications of this disease, such as diabetic nephropathy (DN)...
  31. doi request reprint Role of statins in preventing adverse cardiovascular outcomes in patients with chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Curr Opin Nephrol Hypertens 20:146-52. 2011
    ..Dyslipidemia is a well established cardiovascular risk factor. We summarize key aspects of available evidence relating to beneficial effects of statins in nondialysis-dependent CKD, dialysis-dependent CKD and renal transplant recipients...
  32. pmc Presence and outcomes of kidney disease in patients with pulmonary hypertension
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Respiratory Institute, Medicine Institute, and, Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, Cleveland Clinic Lerner College of Medicine and, Department of Nephrology, Case Western Reserve University, Cleveland, Ohio
    Clin J Am Soc Nephrol 9:855-63. 2014
    ..Pulmonary hypertension is associated with higher mortality rates. The associations of nondialysis-dependent CKD and all-cause mortality in patients with pulmonary hypertension were studied...
  33. pmc Outcomes of patients receiving maintenance dialysis admitted over weekends
    Ankit Sakhuja
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH Electronic address
    Am J Kidney Dis 62:763-70. 2013
    ..We evaluated outcomes in patients on maintenance dialysis therapy admitted over weekends using a national database...
  34. doi request reprint How to design a randomized controlled trial
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Nephrology (Carlton) 15:732-9. 2010
    ..In this article, the key steps that are required to design a randomized controlled trial are summarized...
  35. ncbi request reprint Phosphate binders for preventing and treating bone disease in chronic kidney disease patients
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA, 44195
    Cochrane Database Syst Rev 2:CD006023. 2011
    ..Phosphate binders are widely used to lower serum phosphorus levels in people with chronic kidney disease (CKD) but their impact in CKD remains controversial...
  36. pmc Lifestyle-induced decrease in fat mass improves adiponectin secretion in obese adults
    Karen R Kelly
    1Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 2Department of Nutrition, Case Western Reserve University, School of Medicine, Cleveland, OH 3Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH 4Department of Physiology, Case Western Reserve University, School of Medicine, Cleveland, OH and 5Metabolic Translational Research Center, Cleveland Clinic, Cleveland, OH
    Med Sci Sports Exerc 46:920-6. 2014
    ..5 yr, body mass index = 34.5 ± 0.7 kg·m)...
  37. pmc Cardiac resynchronization therapy in CKD: a systematic review
    Neha Garg
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Clin J Am Soc Nephrol 8:1293-303. 2013
    ..Cardiac resynchronization therapy (CRT) confers morbidity and mortality benefits to selected patients with heart failure. This systematic review examined effects of CRT in CKD patients (estimated GFR [eGFR] <60 ml/min per 1.73 m(2))...
  38. pmc Associations of serum uric acid with cardiovascular events and mortality in moderate chronic kidney disease
    Sankar D Navaneethan
    Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH, USA
    Nephrol Dial Transplant 24:1260-6. 2009
    ..It is unclear whether the presence of kidney disease modifies the associations of uric acid with cardiovascular events and death...
  39. pmc Terlipressin in hepatorenal syndrome: a systematic review and meta-analysis
    Mirela Dobre
    Department of Medicine, Huron Hospital A Cleveland Clinic Hospital, Cleveland, OH, USA
    Int Urol Nephrol 43:175-84. 2011
    ..Hepatorenal syndrome (HRS) is a common complication in patients with cirrhosis or fulminant liver failure. We systematically reviewed the benefits and harms of using terlipressin, a novel vasoconstricting agent in patients with HRS...
  40. pmc Impact of navigators on completion of steps in the kidney transplant process: a randomized, controlled trial
    Catherine Sullivan
    Center for Reducing Health Disparities, Department of Medicine, Case Western Reserve University, Cleveland, OH 44109, USA
    Clin J Am Soc Nephrol 7:1639-45. 2012
    ..This study sought to determine the effect of navigators on completion of steps...