Research Topics
Genomes and GenesSpecies | JOCELYN MCDONALDSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Specification of motoneuron fate in Drosophila: integration of positive and negative transcription factor inputs by a minimal eve enhancerJocelyn A McDonald
Institutes of Neuroscience and Molecular Biology, HHMI, 1254 University of Oregon, Eugene, Oregon 97403, USA
J Neurobiol 57:193-203. 2003..Thus, the eve enhancer integrates multiple positive and negative transcription factor inputs to restrict eve expression to a single precursor cell (GMC4-2a) and its RP2 motoneuron progeny...
Multiple EGFR ligands participate in guiding migrating border cellsJocelyn A McDonald
Department of Biological Chemistry, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205 2185, USA
Dev Biol 296:94-103. 2006..In addition, only Keren and Spitz were expressed at the appropriate stage in the oocyte, the target of border cell migration. Therefore, a complex combination of EGFR and PVR ligands together guide border cells to the oocyte...
PAR-1 kinase regulates epithelial detachment and directional protrusion of migrating border cellsJocelyn A McDonald
Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Curr Biol 18:1659-67. 2008....
PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with TaimanJocelyn A McDonald
Department of Biological Chemistry, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205 2185, USA
Development 130:3469-78. 2003..In addition, we find that taiman and Pvf1 regulate the dynamic localization of E-cadherin in the border cells, possibly accounting for the interaction between these two pathways...
Analysis of cell migration using Drosophila as a model systemJocelyn A McDonald
Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Methods Mol Biol 294:175-202. 2005..In addition, we provide protocols for staining embryos and manipulating gene function in each of the migratory populations. Finally, we offer some advice concerning the analysis and interpretation of mutant phenotypes...
Research Grants
- Regulation of in vivo cell migration by the polarity protein Par-1JOCELYN MCDONALD; Fiscal Year: 2009....
- Regulation of in vivo cell migration by the polarity protein Par-1Jocelyn A McDonald; Fiscal Year: 2010....
- Regulation of in vivo cell migration by the polarity protein Par-1JOCELYN MCDONALD; Fiscal Year: 2009....
