P M McCarthy

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Permanent mechanical circulatory support with an implantable left ventricular assist device
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195, USA
    Ann Thorac Surg 63:1458-61. 1997
  2. ncbi request reprint Risk factors for death after heart transplantation: does a single-center experience correlate with multicenter registries?
    J F McCarthy
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 65:1574-8; discussion 1578-9. 1998
  3. ncbi request reprint A prospective randomized trial of Duraflo II heparin-coated circuits in cardiac reoperations
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 67:1268-73. 1999
  4. ncbi request reprint Implantable LVAD insertion in patients with previous heart surgery
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Ohio 44195, USA
    J Heart Lung Transplant 19:S95-100. 2000
  5. ncbi request reprint Left ventricular reduction surgery with mitral valve repair
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Ohio 44195, USA
    J Heart Lung Transplant 19:S64-7. 2000
  6. ncbi request reprint Noninvasive assessment of mitral inertness [correction of inertance]: clinical results with numerical model validation
    M S Firstenberg
    The Cleveland Clinic Foundation, Cleveland, USA
    Comput Cardiol 28:613-6. 2001
  7. ncbi request reprint Relationship between systolic and diastolic function with improvements in forward stroke volume following reduction in mitral regurgitation
    M S Firstenberg
    The Cleveland Clinic Foundation, Cleveland, USA
    Comput Cardiol 28:177-80. 2001
  8. ncbi request reprint Initial clinical experience of real-time three-dimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy
    T Shiota
    Department of Cardiology, Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Ohio, USA
    Am J Cardiol 84:1068-73. 1999
  9. ncbi request reprint Is repair preferable to replacement for ischemic mitral regurgitation?
    A M Gillinov
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 122:1125-41. 2001
  10. ncbi request reprint Partial left ventriculectomy for dilated cardiomyopathy: is this an alternative to transplantation?
    A Franco-Cereceda
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Thorac Cardiovasc Surg 121:879-93. 2001

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Permanent mechanical circulatory support with an implantable left ventricular assist device
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195, USA
    Ann Thorac Surg 63:1458-61. 1997
    ..He was discharged from the hospital 13 days after the operation, and 5 months postoperatively he had returned to New York Heart Association functional class II...
  2. ncbi request reprint Risk factors for death after heart transplantation: does a single-center experience correlate with multicenter registries?
    J F McCarthy
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 65:1574-8; discussion 1578-9. 1998
    ..This study was performed to (1) evaluate pre-Tx factors affecting mortality in a single-center experience, and (2) compare these factors with risk factors obtained from multicenter registry reports...
  3. ncbi request reprint A prospective randomized trial of Duraflo II heparin-coated circuits in cardiac reoperations
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 67:1268-73. 1999
    ..We hypothesized that the beneficial effects of heparin-coated circuits might be seen in patients who had cardiac reoperations...
  4. ncbi request reprint Implantable LVAD insertion in patients with previous heart surgery
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Ohio 44195, USA
    J Heart Lung Transplant 19:S95-100. 2000
    ..In conclusion adjustment of standard LVAD implant technique can successfully manage most problems posed by patients with previous heart surgery...
  5. ncbi request reprint Left ventricular reduction surgery with mitral valve repair
    P M McCarthy
    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Ohio 44195, USA
    J Heart Lung Transplant 19:S64-7. 2000
    ..Many questions remain to be answered, but many patients have demonstrated early subjective and objective improvement...
  6. ncbi request reprint Noninvasive assessment of mitral inertness [correction of inertance]: clinical results with numerical model validation
    M S Firstenberg
    The Cleveland Clinic Foundation, Cleveland, USA
    Comput Cardiol 28:613-6. 2001
    ..98x - 0.045, r=0.90) and the results of numerical modeling (y=0.96x - 0.16, r=0.84). TM gradients are mainly inertial and, as validated by modeling, can be estimated with echocardiography...
  7. ncbi request reprint Relationship between systolic and diastolic function with improvements in forward stroke volume following reduction in mitral regurgitation
    M S Firstenberg
    The Cleveland Clinic Foundation, Cleveland, USA
    Comput Cardiol 28:177-80. 2001
    ..1%), and was best predicted by (r=0.97, p<0.01) %delta(fSV)[correction of fVS]=34[MRa initial] - 46[MRa final] -0.5[elastance]. Reduced MRa, independent of relaxation and minimally influence by contractility, yield improved fSVs...
  8. ncbi request reprint Initial clinical experience of real-time three-dimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy
    T Shiota
    Department of Cardiology, Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Ohio, USA
    Am J Cardiol 84:1068-73. 1999
    ..The new real-time 3D echocardiography is feasible in patients with cardiomyopathy and may provide a faster and lower cost alternative to MRI for evaluating cardiac function in patients...
  9. ncbi request reprint Is repair preferable to replacement for ischemic mitral regurgitation?
    A M Gillinov
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 122:1125-41. 2001
    ..This study was undertaken to compare mitral valve repair and replacement as treatments for ischemic mitral regurgitation...
  10. ncbi request reprint Partial left ventriculectomy for dilated cardiomyopathy: is this an alternative to transplantation?
    A Franco-Cereceda
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Thorac Cardiovasc Surg 121:879-93. 2001
    ..To determine the late effectiveness of partial left ventriculectomy and risk factors for failure...
  11. ncbi request reprint Is anterior leaflet repair always necessary in repair of bileaflet mitral valve prolapse?
    A M Gillinov
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 68:820-3; discussion 824. 1999
    ..This study was undertaken to evaluate the effectiveness of a strategy of posterior leaflet resection and annuloplasty alone for patients with bileaflet prolapse and no anterior chordal rupture or severe anterior chordal elongation...
  12. ncbi request reprint Results of partial left ventriculectomy for dilated cardiomyopathy: hemodynamic, clinical and echocardiographic observations
    R C Starling
    George M and Linda H Kaufman Center for Heart Failure, Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Coll Cardiol 36:2098-103. 2000
    ..The study was done to prospectively measure the echocardiographic, hemodynamic and clinical outcomes after partial left ventriculectomy (PLV)...
  13. ncbi request reprint Early and late rejection and HLA sensitization at the time of heart transplantation in patients bridged with left ventricular assist devices
    G V Gonzalez-Stawinski
    Department of Thoracic Surgery, Kaufman Center for Heart Failure and The Transplant Center, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Transplant Proc 37:1349-51. 2005
    ....
  14. ncbi request reprint Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion
    K Fukamachi
    Department of Biomedical Engineering, The Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 68:2181-4. 1999
    ..Implantable left ventricular assist device (LVAD) insertion complicated by early right ventricular (RV) failure has a poor prognosis and is generally unpredictable...
  15. ncbi request reprint Atrial L-type Ca2+ currents and human atrial fibrillation
    D R Van Wagoner
    Department of Cardiology and Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circ Res 85:428-36. 1999
    ..The reduction in functional I(Ca) density in myocytes from the atria of chronic AF patients may thus be an adaptive response to the arrhythmia-induced calcium overload...
  16. ncbi request reprint Device-based change in left ventricular shape: a new concept for the treatment of dilated cardiomyopathy
    P M McCarthy
    Department of Cardiology and Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 122:482-90. 2001
    ..We tested a unique new device, the Myosplint device (Myocor, Inc, Maple Grove, Minn), which is designed to change left ventricular shape, reduce left ventricular wall stress, and improve left ventricular systolic function...
  17. ncbi request reprint Fluorescence spectroscopy of endomyocardial tissue post-human heart transplantation: does it correlate with histopathology?
    M H Yamani
    Department of Cardiology, Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Heart Lung Transplant 19:1077-80. 2000
    ..A significant correlation between autofluorescence spectroscopy and heart allograft rejection has been described in the rat heterotropic allograft model. However, the use of this technique in human heart transplants has not been validate...
  18. ncbi request reprint The atherosclerotic aorta at aortic valve replacement: surgical strategies and results
    A M Gillinov
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Thorac Cardiovasc Surg 120:957-63. 2000
    ..2%) patients had a severely atherosclerotic ascending aorta and required hypothermic circulatory arrest to facilitate aortic valve replacement. They form the study group...
  19. ncbi request reprint Mitral inertance in humans: critical factor in Doppler estimation of transvalvular pressure gradients
    S Nakatani
    Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
    Am J Physiol Heart Circ Physiol 280:H1340-5. 2001
    ..65, P < 0.0001). Because mitral inertance causes the velocity to lag significantly behind the actual pressure gradient, it needs to be considered when assessing diastolic filling and the pressure difference across normal mitral valves...
  20. ncbi request reprint Surgical treatments for heart failure
    G S Kumpati
    Department of Thoracic and Cardiovascular Surgery, George M. and Linda H. Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Cardiol Clin 19:669-81. 2001
    ..These therapies are the basis of the discipline of CHF surgery within cardiovascular surgery...
  21. ncbi request reprint Nosocomial bloodstream infections in patients with implantable left ventricular assist devices
    S M Gordon
    Department of Infectious Disease, The Cleveland Clinic Foundation, Ohio, USA
    Ann Thorac Surg 72:725-30. 2001
    ..Strategies for prevention of infection in LVAD recipients should focus on the drive line exit site until technical advances can achieve a totally implantable device...
  22. ncbi request reprint Hypogammaglobulinemia following cardiac transplantation: a link between rejection and infection
    M H Yamani
    Department of Cardiology, Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Heart Lung Transplant 20:425-30. 2001
    ..IgG level may be a useful marker for identifying patients at high risk...
  23. ncbi request reprint Partial left ventriculectomy: sunrise or sunset?
    R C Starling
    Department of Cardiology, Kaufman Center for Heart Failure, Cleveland Clinic Foundation, OH 44195, USA
    Eur J Heart Fail 1:313-7. 1999
    ..PLV does not yield outcomes equivalent to cardiac transplantation based on current selection criteria and requires further investigation to determine its role in the treatment of advanced heart failure...
  24. ncbi request reprint Relationship between early diastolic intraventricular pressure gradients, an index of elastic recoil, and improvements in systolic and diastolic function
    M S Firstenberg
    Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Circulation 104:I330-5. 2001
    ..38[%DeltaIVPG]-8.39, r=0.85). CONCLUSIONS: Improvements in LV function also increase IVPGs. These changes in IVPGs, suggestive of increases in LV suction and elastic recoil, correlate directly with improvements in LV relaxation and ESV...
  25. ncbi request reprint Safety and efficacy of intraarterial thrombolysis for perioperative stroke after cardiac operation
    N Moazami
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 72:1933-7; discussion 1937-9. 2001
    ..CONCLUSIONS: In select patients with acute ischemic stroke after recent cardiac operation, intraarterial thrombolysis appears to be reasonably safe and may lead to neurologic recovery...
  26. ncbi request reprint Left ventricular assist device bridge to recovery: a review of the current status
    G S Kumpati
    George M and Linda H Kaufman Center for Heart Failure, Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 71:S103-8; discussion S114-5. 2001
    ..Despite numerous markers of success, there is a disconnect from the limited clinical successes that are reviewed. The current status and future options to increase the chances of success are highlighted...
  27. ncbi request reprint Clinical experience with 202 adults receiving extracorporeal membrane oxygenation for cardiac failure: survival at five years
    N G Smedira
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 122:92-102. 2001
    ....
  28. ncbi request reprint Clinically available intracorporeal left ventricular assist devices
    P M McCarthy
    Kaufman Center for Heart Failure, Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, OH, USA
    Prog Cardiovasc Dis 43:37-46. 2000
    ..As the problem of infection is reduced, more widespread LVAD use can be anticipated...
  29. ncbi request reprint Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart
    M L Ogletree-Hughes
    Center for Anesthesiology Research, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 104:881-6. 2001
    ..This indicates that functional impairment of cardiac muscle in human heart failure is reversible...
  30. ncbi request reprint High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound
    E M Tuzcu
    Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 103:2705-10. 2001
    ..Detailed, in vivo data on atherosclerosis in young individuals are limited. Intravascular ultrasonography provides a unique opportunity for in vivo characterization of early atherosclerosis in a clinically relevant context...
  31. ncbi request reprint A novel miniature ventricular assist device for hemodynamic support
    M Takagaki
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Ohio 44195, USA
    ASAIO J 47:412-6. 2001
    ..Despite its small diameter, the enabler significantly improved the hemodynamics of failing hearts and may potentially serve as a means of peripheral left ventricular support. Further study is warranted...
  32. ncbi request reprint Ineffectiveness and potential proarrhythmia of atrial pacing for atrial fibrillation prevention after coronary artery bypass grafting
    M K Chung
    Department of Cardiology, The Cleveland Clinic Foundation, Ohio 44195 5245, USA
    Ann Thorac Surg 69:1057-63. 2000
    ..Atrial pacing is often used empirically to suppress atrial ectopy and prevent atrial fibrillation after coronary artery bypass grafting...
  33. ncbi request reprint A simple method of left ventricular reconstruction without patch for ischemic cardiomyopathy
    C Caldeira
    Department of Thoracic and Cardiovascular Surgery, The Kaufman Center for Heart Failure, The Cleveland Clinic Foundation, Ohio 44195, USA
    Ann Thorac Surg 72:2148-9. 2001
    ....
  34. ncbi request reprint Left ventricular assist device as a bridge to recovery: present status
    G S Kumpati
    Department of Thoracic Surgery, George M. and Linda H. Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Ohio 44195, USA
    J Card Surg 16:294-301. 2001
    ..Further studies of topics such as the timing of LVAD implantation and explantation, adjunct medical and surgical therapy, and optimum LVAD weaning protocols might help improve the success of this promising technology...
  35. ncbi request reprint Curative surgery for atrial fibrillation. Current status and minimally invasive approaches
    J L Navia
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Minerva Cardioangiol 52:155-68. 2004
    ..New ablation technologies have been adapted to enable thoracoscopic and minimally invasive surgical AF ablation in patients with isolated AF, extending the possibility of cure to large numbers of patients...
  36. pmc Preload-adjusted maximal power: a novel index of left ventricular contractility in atrial fibrillation
    M Takagaki
    Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Heart 88:170-6. 2002
    ..Left ventricular contractility in atrial fibrillation is known to change in a beat to beat fashion, but there is no gold standard for contractility indices in atrial fibrillation, especially those measured non-invasively...
  37. ncbi request reprint Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation
    C A Carnes
    College of Pharmacy, Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, Ohio, USA
    Circ Res 89:E32-8. 2001
    ..The full text of this article is available at http://www.circresaha.org...
  38. ncbi request reprint Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation
    M J Mihm
    Division of Pharmacology/College of Pharmacy, Ohio State University, Columbus, Ohio 43210, USA
    Circulation 104:174-80. 2001
    ....
  39. ncbi request reprint Novel device to change left ventricular shape for heart failure treatment: device design and implantation procedure
    M Takagaki
    Department of Biomedical Engineering, Lerner Research Institute, Cleveland, Ohio, USA
    ASAIO J 47:244-8. 2001
    ..There were no complications related to the device or procedure. Myosplint implantation to change LV shape is safe and repeatable on a beating cardiomyopathic canine heart. Further study of the procedure will be needed in humans...