Peter Mazzone

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. doi request reprint Quality of life and healthcare use in a randomized controlled lung cancer screening study
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Ann Am Thorac Soc 10:324-9. 2013
  2. pmc Lung cancer screening with computer aided detection chest radiography: design and results of a randomized, controlled trial
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 8:e59650. 2013
  3. pmc The effect of metformin and thiazolidinedione use on lung cancer in diabetics
    Peter J Mazzone
    Respiratory Institute, The Cleveland Clinic, 9500 Euclid Ave, A90, Cleveland, OH 44195, USA
    BMC Cancer 12:410. 2012
  4. doi request reprint Lung cancer screening: examining the issues
    Peter Mazzone
    Critical Care Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:eS1-6. 2012
  5. doi request reprint Preoperative evaluation of the lung resection candidate
    Peter Mazzone
    Critical Care Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:eS17-22. 2012
  6. doi request reprint The rationale for, and design of, a lung cancer screening program
    Peter Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:337-45. 2012
  7. doi request reprint Current and emerging medical treatments for non-small cell lung cancer: a primer for pulmonologists
    Peter Mazzone
    Respiratory Institute, Cleveland Clinic, Mail Code A90, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Respir Med 106:473-92. 2012
  8. pmc Small vessel ischemic disease of the brain and brain metastases in lung cancer patients
    Peter J Mazzone
    Respiratory Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 4:e7242. 2009
  9. doi request reprint Analysis of volatile organic compounds in the exhaled breath for the diagnosis of lung cancer
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Oncol 3:774-80. 2008
  10. pmc Diagnosis of lung cancer by the analysis of exhaled breath with a colorimetric sensor array
    Peter J Mazzone
    Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic, 9500 Euclid Avenue, A90 Cleveland, OH 44195, USA
    Thorax 62:565-8. 2007

Collaborators

Detail Information

Publications48

  1. doi request reprint Quality of life and healthcare use in a randomized controlled lung cancer screening study
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Ann Am Thorac Soc 10:324-9. 2013
    ..Understanding the quality of life of lung cancer screening program participants, and the impact of program participation on quality of life and healthcare use, will help in the assessment of the value of screening...
  2. pmc Lung cancer screening with computer aided detection chest radiography: design and results of a randomized, controlled trial
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 8:e59650. 2013
    ..CAD chest radiography may improve the sensitivity of standard chest radiography while minimizing the risks of CT based screening...
  3. pmc The effect of metformin and thiazolidinedione use on lung cancer in diabetics
    Peter J Mazzone
    Respiratory Institute, The Cleveland Clinic, 9500 Euclid Ave, A90, Cleveland, OH 44195, USA
    BMC Cancer 12:410. 2012
    ..Metformin and the thiazolidinediones (TZDs) may have a protective effect against the development of lung cancer...
  4. doi request reprint Lung cancer screening: examining the issues
    Peter Mazzone
    Critical Care Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:eS1-6. 2012
    ..In this past year, the National Lung Screening Trial reported a significant reduction in cancer-related mortality as a result of screening with chest CT imaging. This will shape the direction of future screening programs...
  5. doi request reprint Preoperative evaluation of the lung resection candidate
    Peter Mazzone
    Critical Care Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:eS17-22. 2012
    ..Smoking cessation and pulmonary rehabilitation are perioperative measures that can improve patients' the short- and long-term outcomes...
  6. doi request reprint The rationale for, and design of, a lung cancer screening program
    Peter Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Cleve Clin J Med 79:337-45. 2012
    ..Time and further technical advances will help to optimize the programs that are developed...
  7. doi request reprint Current and emerging medical treatments for non-small cell lung cancer: a primer for pulmonologists
    Peter Mazzone
    Respiratory Institute, Cleveland Clinic, Mail Code A90, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Respir Med 106:473-92. 2012
    ....
  8. pmc Small vessel ischemic disease of the brain and brain metastases in lung cancer patients
    Peter J Mazzone
    Respiratory Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America
    PLoS ONE 4:e7242. 2009
    ..We aimed to determine if the presence of small vessel ischemic disease (SVID) of the brain is protective against the development of brain metastases in lung cancer patients...
  9. doi request reprint Analysis of volatile organic compounds in the exhaled breath for the diagnosis of lung cancer
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Oncol 3:774-80. 2008
    ....
  10. pmc Diagnosis of lung cancer by the analysis of exhaled breath with a colorimetric sensor array
    Peter J Mazzone
    Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic, 9500 Euclid Avenue, A90 Cleveland, OH 44195, USA
    Thorax 62:565-8. 2007
    ..The colours of these spots change based on the chemicals with which they come into contact. In this proof of principle study, the ability of this sensor system to detect a pattern of VOCs unique to lung cancer is assessed...
  11. ncbi request reprint Cell-mediated immune response to influenza vaccination in lung transplant recipients
    Peter J Mazzone
    Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Heart Lung Transplant 23:1175-81. 2004
    ..Cellular immune mechanisms serve an important role in influenza clearance. The cellular immune response to influenza vaccination has not been studied in transplant populations...
  12. ncbi request reprint Lung cancer screening: is it time for a change in policy?
    Peter Mazzone
    Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Cleve Clin J Med 74:441-8. 2007
    ..These questions warrant further study prior to accepting CT screening as the standard of care. Hopefully, much of this knowledge will be gained when the results of ongoing controlled studies are available...
  13. ncbi request reprint Lung cancer screening
    Peter J Mazzone
    Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Curr Oncol Rep 9:265-74. 2007
    ..Current guidelines remain vague as randomized trials are being completed and technologic advances are occurring. The ultimate face of a successful lung cancer screening program is yet to be defined...
  14. ncbi request reprint Preoperative evaluation of the lung cancer resection candidate
    Peter J Mazzone
    Respiratory Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
    Expert Rev Respir Med 4:97-113. 2010
    ..Testing algorithms are provided from these guidelines. In addition, perioperative considerations and alternative surgical approaches are discussed...
  15. doi request reprint Lung cancer screening: an update, discussion, and look ahead
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Curr Oncol Rep 12:226-34. 2010
    ..I then discuss the evidence related to the areas that are currently debated, describe the ongoing trials that will help to clarify these issues, and speculate about the future...
  16. pmc Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area
    Peter Mazzone
    Department of Pulmonary Medicine, Cleveland Clinic Lerner College of Medicine, E 100 St, Cleveland, OH 44106, USA
    Int J Environ Res Public Health 7:4111-26. 2010
    ..We also discuss the potential toxicity of recently marketed "potential-reduced exposure products"...
  17. ncbi request reprint Lung cancer: Preoperative pulmonary evaluation of the lung resection candidate
    Peter J Mazzone
    Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, OH, USA
    Am J Med 118:578-83. 2005
    ..Published guidelines help to direct the order of testing, permitting us to offer resection to as many patients as possible...
  18. pmc Exhaled breath analysis with a colorimetric sensor array for the identification and characterization of lung cancer
    Peter J Mazzone
    Respiratory Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Oncol 7:137-42. 2012
    ..Breath biosignature-based classification of homogeneous subgroups of lung cancer may be more accurate than a global breath signature. Combining breath biosignatures with clinical risk factors may improve the accuracy of the signature...
  19. ncbi request reprint Endocrine paraneoplastic syndromes in lung cancer
    Peter J Mazzone
    Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
    Curr Opin Pulm Med 9:313-20. 2003
    ..Knowledge about the clinical manifestations, pathophysiology, and treatment of these syndromes has evolved over time. This article provides an up-to-date overview of this knowledge...
  20. pmc ProApolipoprotein A1: a serum marker of brain metastases in lung cancer patients
    Nicola Marchi
    Cerebrovascular Research, Department of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio 44195, USA
    Cancer 112:1313-24. 2008
    ..However, a confounding factor was the presence of BBB changes due to cerebrovascular disease...
  21. doi request reprint Comprehensive analysis of pulmonary function Test (PFT) changes after stereotactic body radiotherapy (SBRT) for stage I lung cancer in medically inoperable patients
    Kevin L Stephans
    Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Oncol 4:838-44. 2009
    ..To assess for variables predicting pulmonary function test (PFT) changes after stereotactic body radiotherapy (SBRT) for medically inoperable stage I lung cancer...
  22. doi request reprint A comparison of four versions of a computer-aided detection system for pulmonary nodules on chest radiographs
    Moulay Meziane
    Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Thorac Imaging 27:58-64. 2012
    ..We evaluated the performance of a Food and Drug Administration-approved system and 3 of its subsequent versions to determine their potential to improve readers' accuracy...
  23. doi request reprint Lung cancer: preoperative pulmonary evaluation of the lung resection candidate
    Hataya Poonyagariyagorn
    Department of Pulmonary, Allergy and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Semin Respir Crit Care Med 29:271-84. 2008
    ..Knowledge of alternative treatment options will help to guide those deemed unfit for resection...
  24. ncbi request reprint S100beta as a predictor of brain metastases: brain versus cerebrovascular damage
    Michael A Vogelbaum
    Brain Tumor Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cancer 104:817-24. 2005
    ....
  25. doi request reprint Bronchogenic carcinoma after lung transplantation: characteristics and outcomes
    Omar A Minai
    Departments of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Oncol 3:1404-9. 2008
    ..Lung cancer may occur in the lung transplant population because many patients are former smokers. Not much is known about risk factors and outcomes in these patients...
  26. doi request reprint A comparison of two stereotactic body radiation fractionation schedules for medically inoperable stage I non-small cell lung cancer: the Cleveland Clinic experience
    Kevin L Stephans
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Oncol 4:976-82. 2009
    ..To assess the impact of fractionation upon tumor control and toxicity in medically inoperable early stage lung cancer patients treated with stereotactic body radiotherapy...
  27. doi request reprint A comparison of follow-up recommendations by chest radiologists, general radiologists, and pulmonologists using computer-aided detection to assess radiographs for actionable pulmonary nodules
    Moulay Meziane
    Imaging Institute, Cleveland Clinic Foundation, OH, USA
    AJR Am J Roentgenol 196:W542-9. 2011
    ..The primary objective of our study was to compare the effect of a chest radiography computer-aided detection (CAD) system on the follow-up recommendations of chest radiologists, general radiologists, and pulmonologists...
  28. pmc In vitro assessment of tobacco smoke toxicity at the BBB: do antioxidant supplements have a protective role?
    Mohammed Hossain
    Cerebrovascular Research, Department of Pulmonary Medicine, Cleveland Clinic, Cleveland, OH 44195 USA
    BMC Neurosci 12:92. 2011
    ....
  29. doi request reprint What's the control in studies measuring the effect of computer-aided detection (CAD) on observer performance?
    Nancy A Obuchowski
    Quantitative Health Sciences, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Acad Radiol 17:761-7. 2010
    ..The crossover design is considered the most valid. The sequential design takes less time and is less expensive but may be biased. We conducted a study to investigate the differences between these two designs...
  30. ncbi request reprint Impact of induction concurrent chemoradiotherapy on pulmonary function and postoperative acute respiratory complications in esophageal cancer
    Rony M Abou-Jawde
    Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Taussig Cancer Center, R35, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Chest 128:250-5. 2005
    ..To evaluate the effects of induction concurrent chemoradiotherapy (cCRT) on pulmonary function and postoperative acute respiratory complications (PARCs)...
  31. pmc Electromagnetic navigation diagnostic bronchoscopy: a prospective study
    Thomas R Gildea
    Department of Pulmonary, Allergy and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Respir Crit Care Med 174:982-9. 2006
    ..Electromagnetic navigation bronchoscopy using superDimension/Bronchus System is a novel method to increase diagnostic yield of peripheral and mediastinal lung lesions...
  32. doi request reprint Bias, underestimation of risk, and loss of statistical power in patient-level analyses of lesion detection
    Nancy A Obuchowski
    Department of Quantitative Health Sciences JJN3 and the Imaging Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Eur Radiol 20:584-94. 2010
    ..For tests designed to find and diagnose lesions, e.g., lung nodules, the usual definitions of sensitivity and specificity may be misleading. In this paper we describe and compare five measures of accuracy of lesion detection...
  33. ncbi request reprint Extrapleural pneumonectomy for scimitar syndrome
    David P Mason
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 132:704-5. 2006
  34. ncbi request reprint Interpreting pulmonary function tests: recognize the pattern, and the diagnosis will follow
    Feyrouz Al-Ashkar
    Department of General Internal Medicine, The Cleveland Clinic, The Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 70:866, 868, 871-3, passim. 2003
    ..Once a pattern is recognized, the diagnosis will often follow...
  35. ncbi request reprint Discordant utility of ideal body weight and body mass index as predictors of mortality in lung transplant recipients
    Daniel A Culver
    Department of Pulmonary and Critical Care Medicine, Cleveland, OH 44195, USA
    J Heart Lung Transplant 24:137-44. 2005
    ..A prior study used body mass index (BMI) to suggest greater mortality risk in obese allograft recipients, but the number of studied patients was small...
  36. ncbi request reprint Multiple pulmonary nodules in an elderly woman
    Gustavo A Heresi
    Deparment of Pulmonary, Allergy and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Oncol 1:580-1. 2006
  37. doi request reprint Histologic and molecular characterization of lung cancer with tissue obtained by electromagnetic navigation bronchoscopy
    Duc Ha
    Department of Internal Medicine Respiratory Institute Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    J Bronchology Interv Pulmonol 20:10-5. 2013
    ....
  38. ncbi request reprint Bronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancer
    Peter Mazzone
    Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Clin Chest Med 23:137-58, ix. 2002
    ..This article provides a critical overview of indications, diagnostic yield, and limitations of bronchoscopy and TNB in the diagnosis of lung cancer...
  39. ncbi request reprint A rational approach to the evaluation and treatment of the infected patient in the intensive care unit
    Jaime F Avecillas
    Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Clin Chest Med 24:645-69. 2003
    ..The information provided in this article, used in association with good clinical judgment, will help the critical care physician provide optimal initial management of the infected patient in the ICU...
  40. pmc Detection of lung cancer by sensor array analyses of exhaled breath
    Roberto F Machado
    Department of Pathobiology, Lerner Research Institute, Cleveland, OH, USA
    Am J Respir Crit Care Med 171:1286-91. 2005
    ..Electronic noses are successfully used in commercial applications, including detection and analysis of volatile organic compounds in the food industry...
  41. ncbi request reprint The pulmonologist's perspective regarding the solitary pulmonary nodule
    Peter J Mazzone
    Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Semin Thorac Cardiovasc Surg 14:250-60. 2002
    ..Management decisions for these nodules are influenced by their low prevalence of malignancy and small size. Future advances will add to our ability to effectively meet our stated goal...
  42. ncbi request reprint Hypotension in the intensive care unit
    Ahmed Al-Hazzouri
    Department of Internal Medicine, Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 73:1091-7. 2006
  43. ncbi request reprint A small pulmonary nodule, found incidentally
    Aqeel A Chowdhry
    Department of Diagnostic Radiology, Cleveland Clinic, Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 74:531-3. 2007
  44. ncbi request reprint Does noninvasive positive pressure ventilation have a role in managing hypercapnic respiratory failure due to an acute exacerbation of COPD?
    Ari J Gershman
    Department of General Internal Medicine, Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 75:458-61. 2008
  45. ncbi request reprint How many ways can we say that cigarette smoking is bad for you?
    Peter J Mazzone
    Chest 126:1717-8. 2004
  46. ncbi request reprint Is lung cancer in the nonsmoker a different disease?
    Peter J Mazzone
    Chest 126:326-9. 2004
  47. ncbi request reprint Impact of positron emission tomography on clinical decision making
    Gustavo A Heresi
    Chest 130:300-1. 2006
  48. ncbi request reprint Cause and effect in lung cancer: fueling the fire
    Peter J Mazzone
    Chest 128:6-8. 2005