Research Topics
| Colleen G KochSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Publications
Statin therapyColleen G Koch
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Department of Cardiothoracic Anesthesia, Cleveland Clinic, USA
Curr Pharm Des 18:6284-90. 2012..Further research is necessary to determine specific patients who would best benefit from preoperative statin therapy, the dose and duration of therapy prior to surgical interventions and the influence of administration following surgery...
When the timing is right: Antibiotic timing and infection after cardiac surgeryColleen G Koch
Department of Cardiothoracic Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA
J Thorac Cardiovasc Surg 144:931-937.e4. 2012....
What are the real rates of postoperative complications: elucidating inconsistencies between administrative and clinical data sourcesColleen G Koch
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, OH 44122, USA
J Am Coll Surg 214:798-805. 2012..We examined administrative and clinical data and 2 clinical data sources in 4 surgical morbidity outcomes...
Gender profiling in coronary artery bypass graftingColleen Gorman Koch
Department of Cardiothoracic Anesthesia G 3, The Cleveland Clinic Foundation, Ohio 44195, USA
J Thorac Cardiovasc Surg 126:2044-51. 2003..Therefore, the objective of this study was to characterize the difference between the female and male profiles of patients presenting for coronary artery bypass grafting...
Health-related quality of life after cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Ohio 44195, USA
Semin Cardiothorac Vasc Anesth 12:203-17. 2008..Strategies for analyzing HRQOL data are inconsistent primarily because the data frequently do not meet underlying assumptions of traditional methods for statistical analyses and require a careful analytic approach...
Red cell transfusion is associated with an increased risk for postoperative atrial fibrillationColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Ann Thorac Surg 82:1747-56. 2006..Therefore, we tested the hypothesis that red blood cell transfusion increases the risk of postoperative AF for patients undergoing cardiac surgery...
Socioeconomic status and comorbidity as predictors of preoperative quality of life in cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic, Cleveland, Ohio 44195, USA
J Thorac Cardiovasc Surg 136:665-72, 672.e1. 2008....
Effect of functional health-related quality of life on long-term survival after cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio 44195, USA
Circulation 115:692-9. 2007..Our objective was to determine whether the Duke Activity Status Index (DASI) was predictive of subsequent time-related survival after recovery from cardiac surgery...
Invited commentaryColleen Gorman Koch
Department of Cardiothoracic Anesthesia (G-3, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
Ann Thorac Surg 85:487. 2008
Duration of red-cell storage and complications after cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
N Engl J Med 358:1229-39. 2008..We tested the hypothesis that serious complications and mortality after cardiac surgery are increased when transfused red cells are stored for more than 2 weeks...
Transfusion and pulmonary morbidity after cardiac surgeryColleen Koch
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio 44195, USA
Ann Thorac Surg 88:1410-8. 2009..Our objective was to determine the prevalence of pulmonary morbidity related to transfusion and whether TRALI consensus-criteria are applicable to cardiac surgery...
Persistent effect of red cell transfusion on health-related quality of life after cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Ann Thorac Surg 82:13-20. 2006..Our objective was to investigate the relationship between perioperative red blood cell and component transfusion and functional health-related quality of life 6 to 12 months after cardiac surgery...
Transfusion in coronary artery bypass grafting is associated with reduced long-term survivalColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Ann Thorac Surg 81:1650-7. 2006....
Gender and cardiac surgeryColleen Gorman Koch
Department of Cardiothoracic Anesthesia, G 3, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Anesthesiol Clin North America 21:675-89. 2003..As further knowledge accumulates, it is hoped that gender-specific risk factors can be mitigated and protective factors exploited, thereby improving the outcomes for all cardiac surgery patients...
Gender and outcomes after coronary artery bypass grafting: a propensity-matched comparisonColleen Gorman Koch
Department of Cardiothoracic Anesthesia G 3, The Cleveland Clinic Foundation, Ohio 44195, USA
J Thorac Cardiovasc Surg 126:2032-43. 2003..Our objective is to determine whether gender is a marker or a causal influence for poor outcomes after coronary revascularization...
Socioeconomic position, not race, is linked to death after cardiac surgeryColleen G Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic, Ohio 44195, USA
Circ Cardiovasc Qual Outcomes 3:267-76. 2010..However, there is a complex interplay between race, sex, and socioeconomic position (SEP). In our investigation we sought to identify which of these was the driver of risk-adjusted survival...
Health-related quality of life after coronary artery bypass grafting: a gender analysis using the Duke Activity Status IndexColleen Gorman Koch
Department of Cardiothoracic Anesthesia G 3, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Thorac Cardiovasc Surg 128:284-95. 2004....
Impact of prosthesis-patient size on functional recovery after aortic valve replacementColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Circulation 111:3221-9. 2005..Our objectives were to examine the impact of valve replacement, continuous prosthesis-patient size, and other factors on functional recovery after aortic valve replacement (AVR) with the Duke Activity Status Index (DASI)...
Nadir hematocrit during cardiopulmonary bypass: end-organ dysfunction and mortalityGabriel Loor
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA
J Thorac Cardiovasc Surg 144:654-662.e4. 2012..To discover the effects of the lowest hematocrit during cardiopulmonary bypass on end-organ function and mortality in patients who did not receive red blood cell transfusion and to identify predictors of nadir hematocrit...
Preoperative statin therapy is not associated with a reduced incidence of postoperative acute kidney injury after cardiac surgeryMaged Argalious
Department of General Anesthesiology, Cleveland Clinic, 9500 Euclid Ave G30, Cleveland, OH 44195, USA
Anesth Analg 111:324-30. 2010..Our objective was to examine the association between preoperative statin therapy and the prevalence of postoperative acute kidney injury (AKI) in patients undergoing cardiac surgery with the use of cardiopulmonary bypass...
Statin therapy is associated with fewer infections after cardiac operationsMatteo Trezzi
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
Ann Thorac Surg 95:892-900. 2013..Therefore, we examined the association between preoperative statin therapy and infections after cardiac operations and assessed whether statin therapy was associated with lower infection-related mortality...
Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservationGregory Pattakos
Heart and Vascular Institute, Departments of Thoracic and Cardiovascular Surgery, Cleveland Clinic, OH 44195, USA
Arch Intern Med 172:1154-60. 2012..Our objective was to compare morbidity and long-term survival of Witnesses undergoing cardiac surgery with a similarly matched group of patients who received transfusions...
Morbidity of bleeding after cardiac surgery: is it blood transfusion, reoperation for bleeding, or both?Alessandro Vivacqua
Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Ann Thorac Surg 91:1780-90. 2011....
Influence of concentric left ventricular remodeling on early mortality after aortic valve replacementAndra Ibrahim Duncan
Department of Cardiothoracic Anesthesia, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Ann Thorac Surg 85:2030-9. 2008....
"Renal dose" dopamine is associated with the risk of new-onset atrial fibrillation after cardiac surgeryMaged Argalious
Department of General Anesthesiology, The Cleveland Clinic Foundation, Cleveland OH 44195, USA
Crit Care Med 33:1327-32. 2005..01). Receipt of rDA increased the odds of developing pAF by 74%, independent of the effect of other variables. CONCLUSIONS: Renal-dose dopamine is associated with a 1.74 odds ratio of pAF developing after CABG...
Transfusion increases the risk for vasoplegia after cardiac operationsAndrej Alfirevic
Department of Cardiothoracic Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Ann Thorac Surg 92:812-9. 2011..We investigated the prevalence of mild and profound postoperative vasoplegia, identified factors associated with its development, and examined the role of RBC and component transfusion on the occurrence of postoperative vasoplegia...
Role of intraoperative and postoperative blood glucose concentrations in predicting outcomes after cardiac surgeryAndra E Duncan
Departments of Cardiothoracic Anesthesia and Outcomes Research, Cleveland Clinic, Cleveland, Ohio 44195, USA
Anesthesiology 112:860-71. 2010..Risk associated with decreasing increments of glucose concentrations, hypoglycemia, and diabetic status was also examined...
What does transesophageal echocardiography add to valvular heart surgery?Colleen Gorman Koch
Department of Cardiothoracic Anesthesia, G 3, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Anesthesiol Clin North America 21:587-611. 2003..As the technology of TEE and its application advance, so too should the ability to diagnose and manage valvular pathologies, broaden the range of surgical options, and ultimately improve patient outcomes...
The impact of gender on in-hospital mortality and morbidity after isolated aortic valve replacementAndra Ibrahim Duncan
Department of Cardiothoracic Anesthesia, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Anesth Analg 103:800-8. 2006..88) nor other morbidities. These results suggest that there is no greater than a 2.5-fold increase in risk for females compared with males undergoing AVR. Female gender, however, may impart increased risk for cardiac morbidity after AVR...
Predictors of prolonged postoperative endotracheal intubation in patients undergoing thoracotomy for lung resectionJacek B Cywinski
Department of General Anesthesiology, Cleveland Clinic, Cleveland, OH 44195, USA
J Cardiothorac Vasc Anesth 23:766-9. 2009..The aim of this study was to identify predictors of delayed endotracheal extubation defined as the need for postoperative ventilatory support after open thoracotomy for lung resection...
Increased risk associated with combined carotid endarterectomy and coronary artery bypass graft surgery: a propensity-matched comparison with isolated coronary artery bypass graft surgeryJacek B Cywinski
Department of General Anesthesia, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
J Cardiothorac Vasc Anesth 20:796-802. 2006..The present study objective was to compare morbidity and mortality outcomes in well-matched patients who underwent combined CEA/CABG surgery with patients undergoing isolated CABG surgery with and without a history of a prior CEA...
Prevalence of risk factors, and not gender per se, determines short- and long-term survival after coronary artery bypass surgeryColleen Gorman Koch
Cleveland Clinic Foundation, OH, USA
J Cardiothorac Vasc Anesth 17:585-93. 2003..Studies that have compared postoperative survival in women and men beyond hospital discharge report disparate results with regard to the independent effect of gender per se on ultimate survival...
Transverse sinus hemangiomaBrian Fitzsimons
Department of General Anesthesiology, The Cleveland Clinic Foundation, Cleveland, OH, USA
Anesth Analg 106:63-4. 2008
The effect of postoperative gastrointestinal complications in patients undergoing coronary artery bypass surgeryJosé L Díaz-Gómez
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio 45195, USA
Ann Thorac Surg 90:109-15. 2010..We thus identified variables associated with GI complications and analyzed their effect on postoperative mortality in patients undergoing isolated CABG...
Platelet transfusion in cardiac surgery does not confer increased risk for adverse morbid outcomesTory McGrath
Department of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio, USA
Ann Thorac Surg 86:543-53. 2008..Our objective was to examine the impact of platelet transfusion on outcomes in cardiac surgery controlling perioperative risk factors...
Recent metformin ingestion does not increase in-hospital morbidity or mortality after cardiac surgeryAndra I Duncan
Department of Cardiothoracic Anesthesia, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Anesth Analg 104:42-50. 2007..In this investigation we sought to determine the influence of metformin treatment on mortality and morbidity compared with treatment with other oral hypoglycemic drugs in diabetic patients undergoing cardiac surgery...
Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass graftingColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, OH, USA
Crit Care Med 34:1608-16. 2006..Each unit of red cells transfused is associated with incrementally increased risk for adverse outcome...
Case 4--2005. Utility of transesophageal echocardiography in the diagnosis of a previously undetected atrial septal aneurysm with shuntMichelle Capdeville
Department of Anesthesiology, University Hospitals of Cleveland/Case Western Reserve University School of Medicine, 11000 Euclid Avenue, Lakeside 2531, Cleveland, OH 44106, USA
J Cardiothorac Vasc Anesth 19:529-38. 2005
Con: newly appreciated pathophysiology of ischemic heart disease in women mandates changes in perioperative managementColleen Gorman Koch
Anesth Analg 107:33-6. 2008
Preoperative statin intake and morbid events after isolated coronary artery bypass graftingKathirvel Subramaniam
Department of Anesthesiology, UPMC Presbyterian Hospital, Pittsburgh, PA, USA
J Clin Anesth 20:4-11. 2008..To examine the effect of statins on morbidity and mortality in patients after isolated coronary artery bypass grafting (CABG)...
Long-term benefits of coronary bypass surgery: are the gains for women less than for men?Viola Vaccarino
J Thorac Cardiovasc Surg 126:1707-11. 2003
