Research Topics
| Leonardo KapuralSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Publications
Successful treatment of lumbar discogenic pain using intradiscal biacuplasty in previously discectomized discLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Pract 9:130-4. 2009..IDB may be an effective treatment for patients with discogenic pain from previously discectomized discs...
Effective cervical spinal cord stimulation for bilateral lower extremities pain: technical reportLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Pract 8:117-9. 2008- Technical aspects of spinal cord stimulation for managing chronic visceral abdominal pain: the results from the national surveyLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Med 11:685-91. 2010..CONCLUSION: In conclusion, it seems that the SCS for the treatment of the abdominal visceral pain may provide a positive patient long-term experience, significant improvements in pain scores and a decrease in opioid use... - Value of the magnetic resonance imaging in patients with painful lumbar spinal stenosis (LSS) undergoing lumbar epidural steroid injectionsLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, OH 44195, USA
Clin J Pain 23:571-5. 2007.... - Botulinum toxin occipital nerve block for the treatment of severe occipital neuralgia: a case seriesLeonardo Kapural
Pain Management Department, Division of Anesthesiology, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Pract 7:337-40. 2007..The functional capacity improvement measured by PDI was profound enough in the majority of the patients to allow patients to resume their regular daily activities for a period of time... - Histological changes and temperature distribution studies of a novel bipolar radiofrequency heating system in degenerated and nondegenerated human cadaver lumbar discsLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Pain Med 9:68-75. 2008..In our study we used two human cadaver lumbar spines, one moderately to severely degenerated and the other mildly degenerated... - Nuclear, intradiscal hemangiomaLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Pract 8:114-6. 2008 - Spinal cord stimulation for chronic visceral abdominal painLeonardo Kapural
Department of Pain Management, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Med 11:347-55. 2010..Spinal cord stimulation (SCS) may reduce pain scores and improve function in patients with chronic visceral abdominal pain. We thus present our large clinical experience in SCS for visceral abdominal pain... - Cooled radiofrequency (RF) of L5 dorsal ramus for RF denervation of the sacroiliac joint: technical reportLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Med 11:53-7. 2010..The objective of this technical report is to evaluate the acute safety of denervating the L5DR using cooled RF electrode... - Cooled radiofrequency system for the treatment of chronic pain from sacroiliitis: the first case-seriesLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Pract 8:348-54. 2008..The majority of patients with chronic SI joint pain experienced a clinically relevant degree of pain relief and improved function following cooled RF of sacral lateral branches and DR of L5 at 3-4 months follow-up... - Intrathecal ziconotide for complex regional pain syndrome: seven case reportsLeonardo Kapural
The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Pract 9:296-303. 2009..Adverse events generally resolved spontaneously, with treatment, or with ziconotide discontinuation/dose reduction. Although further studies are required, ziconotide holds promise as an effective treatment for CRPS... - Intradiscal biacuplasty (IDB) for the treatment of thoracic discogenic painLeonardo Kapural
Department of Pain Management, Cleveland Clinic, Cleveland, OH 44195, USA
Clin J Pain 26:354-7. 2010..Unlike lumbar discogenic pain there is a lack of effective surgical options. Reported here is the treatment of thoracic discogenic pain in 3 patients using a new minimally invasive procedure named intradiscal biacuplasty... - Novel intradiscal biacuplasty (IDB) for the treatment of lumbar discogenic painLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Pract 7:130-4. 2007..Potential advantages of cooled, bipolar radiofrequency to heat the posterior annulus are discussed... - Decreased insulin requirements with spinal cord stimulation in a patient with diabetesLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Anesth Analg 98:745-6, table of contents. 2004..IMPLICATIONS: Spinal cord stimulation when used for control of chronic pain in diabetics may provide additional benefits of improving glycemic control and insulin requirements... - Intradiscal thermal annuloplasty for the treatment of lumbar discogenic pain in patients with multilevel degenerative disc diseaseLeonardo Kapural
Pain Management Center, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk C25, Cleveland, OH 44195, USA
Anesth Analg 99:472-6, table of contents. 2004..0037 and P = 0.041, respectively). We concluded that IDTA is an effective treatment of discogenic pain and that the number of discs affected by degeneration is an important determinant of the procedure outcome... - Occipital nerve electrical stimulation via the midline approach and subcutaneous surgical leads for treatment of severe occipital neuralgia: a pilot studyLeonardo Kapural
Pain Management Center, The Cleveland Clinic Foundation, 9500 Euclid Ave, Desk C25, Cleveland, OH 44195, USA
Anesth Analg 101:171-4, table of contents. 2005..There is only one small midline incision over the upper neck and the strain on the lead extension occurs only with flexion and is minimal with lateral flexion and rotation, which contributes to overall stability of this system... - Intradiscal thermal annuloplasty versus intradiscal radiofrequency ablation for the treatment of discogenic pain: a prospective matched control trialLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Med 6:425-31. 2005..The second technique, radiofrequency posterior annuloplasty (RFA), is used in many interventional pain practices, although studies on the technique's efficacy are lacking. This study compares the effectiveness of those two methods... - Spinal cord stimulation is an effective treatment for the chronic intractable visceral pelvic painLeonardo Kapural
Pain Management Department, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Pain Med 7:440-3. 2006..We are reporting on the value of neurostimulation for chronic visceral pelvic pain in six female patients with the diagnosis of long-standing pelvic pain (history of endometriosis, multiple surgical explorations, and dyspareunia)... - Epidural steroid therapy for back and leg pain: mechanisms of action and efficacyRobert F McLain
The Cleveland Clinic Spine Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Spine J 5:191-201. 2005.... - Intervertebral disc biacuplasty for the treatment of lumbar discogenic pain: results of a six-month follow-upLeonardo Kapural
Department of Pain Management, The Cleveland Clinic, Cleveland, OH 44195, USA
Pain Med 9:60-7. 2008..Thirteen patients completed follow-up questionnaires at 1, 3, and 6 months. Pain disability was evaluated with Oswestry and Short Form (SF)-36 questionnaires... - Tunneled epidural catheter infections in noncancer pain: increased risk in patients with neuropathic pain/complex regional pain syndromeSalim Michel Hayek
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Clin J Pain 22:82-9. 2006..A cohort retrospective study design was undertaken to evaluate the risk of catheter-related infection in patients who underwent a TEC placement to manage their chronic noncancer regional pain over a 5-year period... - Clinical applications of neurostimulation: forty years laterNagy A Mekhail
Department of Pain Management, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Pain Pract 10:103-12. 2010..Research with more vigorous designs is needed to establish evidence-based applications of neuromodulation therapy in emerging indications of pain management... - Ultrasound-guided cervical selective nerve root block: a fluoroscopy-controlled feasibility studySamer N Narouze
Pain Management Department, Cleveland Clinic Foundation, 9500 Euclid Ave C25, Cleveland, OH 44195, USA
Reg Anesth Pain Med 34:343-8. 2009..As ultrasound allows for visualization of soft tissues, nerves, and vessels, thus potentially improving precision and safety, we evaluated its feasibility in cervical nerve root injections... - Spinal cord stimulation for chronic visceral pain secondary to chronic non-alcoholic pancreatitisLeonardo Kapural
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, OH, USA
J Clin Gastroenterol 42:750-1. 2008..Pain Disability Index changed from 62 to 15. Opiate use decreased to none. It seems that SCS may have a significant therapeutic potential for the treatment of visceral pain secondary to chronic pancreatitis... - Opioid-sparing effect of intravenous outpatient ketamine infusions appears short-lived in chronic-pain patients with high opioid requirementsLeonardo Kapural
Departments of Pain Management and Outcomes Research, Cleveland Clinic, Cleveland, OH, USA
Pain Physician 13:389-94. 2010..This study evaluated whether or not repeated outpatient infusions of intravenous ketamine reduced the amount of pain and the amount of opioid requirements for patients suffering with chronic, non-cancerous pain... - Peripheral nerve stimulation for occipital neuralgia: surgical leadsLeonardo Kapural
Pain Management Department, Cleveland Clinic, Cleveland, Ohio, USA
Prog Neurol Surg 24:86-95. 2011..However, disregarding the type of lead used, multiple clinical advantages of this minimally invasive, easily reversible approach include relatively low morbidity and a high treatment efficacy... - Spinal cord stimulation for visceral pain from chronic pancreatitisLeonardo Kapural
Pain Management Department, Anesthesia Institute, Cleveland Clinic, Cleveland, Ohio, USA
Neuromodulation 14:423-6; discussion 426-7. 2011..Here described is a large clinical experience in SCS for severe chronic pancreatitis... - Sphenopalatine ganglion radiofrequency ablation for the management of chronic cluster headacheSamer Narouze
Cleveland Clinic Foundation, Pain Management Department, Cleveland, OH 44195, USA
Headache 49:571-7. 2009..We were interested to examine the effect of such intervention in patients with intractable chronic cluster headache who failed pharmacological management... - Successful treatment of spontaneous cerebrospinal fluid leak headache with fluoroscopically guided epidural blood patch: a report of four casesSalim M Hayek
Department of Pain Management, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Med 4:373-8. 2003..In this report, we describe four consecutive cases that were referred to our pain management department over an 18-month period and were successfully treated with site-directed epidural blood patches... - Erosion of the inferior epigastric artery: a rare complication of intrathecal drug delivery systemsSamer N Narouze
Pain Management Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Pain Med 8:468-70. 2007..This inferior epigastric artery erosion could be avoided by implanting the intrathecal pump laterally away from the rectus abdominus muscle sheath... - Differential epidural block predicts the success of visceral block in patients with chronic visceral abdominal painMaged K Rizk
Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio Department of Pain Management, Cleveland Clinic, Cleveland, Ohio Chronic Pain Center, Wake Forest University Health Sciences, Winston Salem, North Carolina Medicine Institute, Cleveland Clinic, Cleveland, Ohio Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, U S A
Pain Pract 12:595-601. 2012..Contrarily, a value of ≥ 8 would provide a specificity of 92% and may be used to predict success of subsequent visceral block... - Adding triamcinolone to endoscopic ultrasound-guided celiac plexus blockade does not reduce pain in patients with chronic pancreatitisTyler Stevens
Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ccf org
Clin Gastroenterol Hepatol 10:186-91, 191.e1. 2012..Triamcinolone is often mixed with bupivacaine to lengthen the analgesic effect. We investigated whether addition of triamcinolone increases and lengthens pain relief compared with EUS-CPB with only bupivacaine... - Pre-transplant MELD and sodium MELD scores are poor predictors of graft failure and mortality after liver transplantationJacek B Cywinski
Departments of General Anesthesiology and Outcomes Research, Transplantation Center, Cleveland Clinic, Cleveland, OH, USA
Hepatol Int 5:841-9. 2011..We, therefore, evaluated and compared the ability of the sodium MELD and MELD scores to predict graft and patient survival after OLT... - Supraorbital nerve electric stimulation for the treatment of intractable chronic cluster headache: a case reportSamer N Narouze
Pain Management Department, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Headache 47:1100-2. 2007..We describe a patient with intractable chronic cluster headache that responded well to supraorbital nerve electric stimulation... - Epidural steroids for back and leg pain: mechanism of action and efficacyRobert F McLain
The Cleveland Clinic Spine Institute, The Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 71:961-70. 2004..We review the rationale, available data, techniques, and indications for these injections... - Morphologic abnormalities are poorly predictive of visceral pain in chronic pancreatitisRubin Bahuva
From the Departments of Hospital Medicine and General Surgery, Cleveland Clinic, Cleveland, OH Wake Forest University Baptist Medical Center and Carolinas Pain Institute, Winston Salem, NC and Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH
Pancreas 42:6-10. 2013..We investigated the correlation of pancreatic structural abnormalities evident on imaging tests with the presence of visceral pain on DNB... - An effective treatment of severe complex regional pain syndrome type 1 in a child using high doses of intrathecal ziconotideMichael Stanton-Hicks
J Pain Symptom Manage 32:509-11. 2006 - Intervertebral disk cooled bipolar radiofrequency (intradiskal biacuplasty) for the treatment of lumbar diskogenic pain: a 12-month follow-up of the pilot studyLeonardo Kapural
Pain Med 9:407-8. 2008 - A randomized, double-blind, controlled trial: intradiscal electrothermal therapy versus placebo for the treatment of chronic discogenic low back painLeonardo Kapural
Spine 31:1636; author reply 1636-7. 2006