Dirk Hubmacher

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. Hubmacher D, Wang L, Mecham R, Reinhardt D, Apte S. Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015;8:487-99 pubmed publisher
    ..Our studies suggest that the bronchial epithelial dysplasia accompanying microfibril dysregulation in Adamtsl2(-/-) mice cannot be reversed by TGFβ neutralization, and thus might be mediated by other mechanisms. ..
  2. Hubmacher D, Apte S. ADAMTS proteins as modulators of microfibril formation and function. Matrix Biol. 2015;47:34-43 pubmed publisher
    ..Here, the genetics and molecular biology of this subset of ADAMTS proteins is discussed from the perspective of how they might contribute to fully functional or function-specific microfibrils. ..
  3. Hubmacher D, Apte S. Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function. Cell Mol Life Sci. 2011;68:3137-48 pubmed publisher