Hubmacher D, Wang L, Mecham R, Reinhardt D, Apte S. Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015;8:487-99 pubmed publisher
..Our studies suggest that the bronchial epithelial dysplasia accompanying microfibril dysregulation in Adamtsl2(-/-) mice cannot be reversed by TGFÎ² neutralization, and thus might be mediated by other mechanisms. ..
Hubmacher D, Apte S. ADAMTS proteins as modulators of microfibril formation and function. Matrix Biol. 2015;47:34-43 pubmed publisher
..Here, the genetics and molecular biology of this subset of ADAMTS proteins is discussed from the perspective of how they might contribute to fully functional or function-specific microfibrils. ..
Hubmacher D, Apte S. Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function. Cell Mol Life Sci. 2011;68:3137-48 pubmed publisher