Research Topics
| Sajal GuptaSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
| Collaborators
|
Detail Information
Publications
Impact of ovarian endometrioma on assisted reproduction outcomesSajal Gupta
Reproductive Research Centre, Glickman Urological Institute and the Department of Obstetrics Gynecology, Cleveland Clinic Foundation, Cleveland, OH, USA
Reprod Biomed Online 13:349-60. 2006..002). Prospective randomized controlled trials are needed to assess whether surgical treatment versus no surgical treatment improves pregnancy outcomes in patients with ovarian endometrioma undergoing assisted reproduction cycles...
Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markersS Gupta
Reproductive Research Center, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Minerva Ginecol 58:527-51. 2006..Potential new therapeutic agents include modulators, such as cytokine receptor blockers and angiogenic receptor blockers, presently used for treating endometriosis...
Semen characteristics and sperm DNA fragmentation in infertile men with low and high levels of seminal reactive oxygen speciesReda Mahfouz
Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 94:2141-6. 2010..To examine sperm motility, total antioxidant level (TAC), DNA fragmentation, and medical history in infertile men with high seminal high reactive oxygen species (ROS)...
Lipid peroxidation and antioxidant status in preeclampsia: a systematic reviewSajal Gupta
Glickman Urological and Kidney Institute, Cleveland, OH 44195, USA
Obstet Gynecol Surv 64:750-9. 2009..Preeclampsia is characterized by increased lipid peroxidation and diminished antioxidant capacity; however, there is no consensus as to the extent of these conditions...
Oxidative stress and its implications in female infertility - a clinician's perspectiveAshok Agarwal
Centre for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Department of Obstetrics Gynecology and Glickman Urological Institute, The Cleveland Clinic Foundation, OH 44195, USA
Reprod Biomed Online 11:641-50. 2005..This review discusses the sources of ROS in media used in IVF-embryo transfer and strategies to overcome OS in oocyte in-vitro maturation, in-vitro culture and sperm preparation techniques...
The role of oxidative stress in spontaneous abortion and recurrent pregnancy loss: a systematic reviewSajal Gupta
Reproductive Research Center, Cleveland Clinic, Cleveland, Ohio, USA
Obstet Gynecol Surv 62:335-47; quiz 353-4. 2007....
Role of oxidative stress in endometriosisSajal Gupta
Centre for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics-Gynecology, The Cleveland Clinic Foundation, OH, USA
Reprod Biomed Online 13:126-34. 2006..Results of the limited number of animal and human trials need to be corroborated by larger randomized controlled trials...
Pathogenic mechanisms in endometriosis-associated infertilitySajal Gupta
Reproductive Research Center, Department of Obstetrics and Gynecology and Glickman Urological Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 90:247-57. 2008..To review the mechanisms by which endometriosis may affect reproductive function...
Reactive oxygen species levels are independent of sperm concentration, motility, and abstinence in a normal, healthy, proven fertile man: a longitudinal studyNisarg R Desai
Center for Reproductive Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 94:1541-3. 2010..We suggest that fluctuation in seminal ROS values may be related to physiologic or transient changes in spermatogenesis...
Redox considerations in female reproductive function and assisted reproduction: from molecular mechanisms to health implicationsAshok Agarwal
Reproductive Research Center, Department of Obstetrics and Gynecology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Antioxid Redox Signal 10:1375-403. 2008..Although antioxidants such as folate, zinc, and thiols may help enhance fertility, the available data are contentious and must be evaluated in controlled studies with larger populations...
The role of free radicals and antioxidants in reproductionAshok Agarwal
Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and the Department of Obstetrics Gynecology, Cleveland Clinic, Cleveland, Ohio 44195, USA
Curr Opin Obstet Gynecol 18:325-32. 2006..This review summarizes the role of free radicals and oxidative stress in the pathophysiology of human reproduction...
Fluctuations in total antioxidant capacity, catalase activity and hydrogen peroxide levels of follicular fluid during bovine folliculogenesisSajal Gupta
Center for Reproductive Medicine, Obstetrics and Gynecology and Women s Health Institute, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A19 1, Cleveland, OH 44195, USA
Reprod Fertil Dev 23:673-80. 2011..Future studies must focus on other reactive oxygen species and their various scavenger types during antral folliculogenesis...
The role of placental oxidative stress and lipid peroxidation in preeclampsiaSajal Gupta
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and the Department of Obstetrics-Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Obstet Gynecol Surv 60:807-16. 2005....
TUNEL as a test for sperm DNA damage in the evaluation of male infertilityRakesh K Sharma
Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA
Urology 76:1380-6. 2010....
Evaluation of peritoneal fluid hemosiderin-laden macrophages in biopsy-proven endometriosisMohamed Ali Bedaiwy
Reproductive Research Center, Minimally Invasive Surgery Center, Department of Obstetrics Gynecology, Cleveland Clinic, 9500 Euclid Avenue, A 81, Cleveland, Ohio 44195, USA
Anal Quant Cytol Histol 34:23-7. 2012..To evaluate peritoneal fluid hemosiderin-laden macrophages (H-LMs) in patients with endometriosis compared to controls...
Role of oxidative stress in female reproductionAshok Agarwal
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Reprod Biol Endocrinol 3:28. 2005..Serial measurement of oxidative stress biomarkers in longitudinal studies may help delineate the etiology of some of the diosorders in female reproduction such as preeclampsia...
The effects of oxidative stress on female reproduction: a reviewAshok Agarwal
Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA
Reprod Biol Endocrinol 10:49. 2012....
Potential markers for detection and monitoring of ovarian cancerBrandon J D Rein
Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
J Oncol 2011:475983. 2011..Detection testing of biomarkers with long-term stability and combination panels of markers, will likely lead to effective screening strategies with high specificity and sensitivity for early detection of ovarian cancer...
Female sexual dysfunction: classification, pathophysiology, and managementRupesh Raina
Glickman Urological Institute and Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Fertil Steril 88:1273-84. 2007..In this article we summarize the pathophysiology and classification of female sexual dysfunction, with special emphasis on the relationship between female sexual dysfunction and pelvic surgeries...
