Research Topics
| A Z FuSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Absenteeism and short-term disability associated with breast cancerAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Breast Cancer Res Treat 130:235-42. 2011..001), respectively, per breast cancer patient per year. This study suggests that breast cancer is associated with work-related productivity loss within the first year of diagnosis that may be a substantial cost to employers...
Utilities should not be multiplied: evidence from the preference-based scores in the United StatesAlex Z Fu
From the Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio 44195, USA
Med Care 46:984-90. 2008..The multiplicative estimator is a widespread choice among them. Our study is to empirically test the accuracy of the multiplicative estimator and compare it with other estimators...
Impact of fear of insulin or fear of injection on treatment outcomes of patients with diabetesAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Curr Med Res Opin 25:1413-20. 2009..This study was undertaken to conduct a systematic review of the impact of fear of insulin/injection on the treatment outcomes of diabetes patients...
Health care and productivity costs associated with diabetic patients with macrovascular comorbid conditionsAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA
Diabetes Care 32:2187-92. 2009..To examine and quantify from the societal perspective the impact of macrovascular comorbid conditions (MVCCs) on health care and productivity costs in diabetic patients in the U.S...
Effect of Medicare Part D on potentially inappropriate medication use by older adultsAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Am Geriatr Soc 58:944-9. 2010..To empirically estimate changes of potentially inappropriate medication (PIM) use attributable to the Medicare Part D prescription drug benefit...
Pre-existing cardiovascular diseases and glycemic control in patients with type 2 diabetes mellitus in Europe: a matched cohort studyAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA
Cardiovasc Diabetol 9:15. 2010..Our aim was to examine the degree of glycemic control among T2DM patients in Europe with and without pre-existing CVD...
Impact of concurrent macrovascular co-morbidities on healthcare utilization in patients with type 2 diabetes in Europe: a matched studyA Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Diabetes Obes Metab 12:631-7. 2010..To examine and to quantify the impact of concurrent macrovascular co-morbidities (MVC) on healthcare resource utilization among patients with type 2 diabetes mellitus (T2DM) in Europe...
Marginal differences in health-related quality of life of diabetic patients with and without macrovascular comorbid conditions in the United StatesAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Avenue JJN3 01, Cleveland, OH 44195, USA
Qual Life Res 20:825-32. 2011..To examine and quantify, at the US national level, the marginal differences in health-related quality of life (HRQoL) of diabetic patients with and without macrovascular comorbid conditions (MaVCC)...
Underutilization of statins in patients with type 2 diabetes in US clinical practice: a retrospective cohort studyAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Curr Med Res Opin 27:1035-40. 2011..Factors associated with receiving a statin prescription were also determined...
Treatment intensification in patients with type 2 diabetes who failed metformin monotherapyA Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Diabetes Obes Metab 13:765-9. 2011..To evaluate the time to and factors associated with treatment intensification in patients with type 2 diabetes who failed metformin monotherapy...
Healthcare expenditures and patient satisfaction: cost and quality from the consumer's perspective in the USAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Curr Med Res Opin 24:1385-94. 2008..Using patient satisfaction as a quality indicator, we seek to identify the relationship between healthcare cost and quality from the perspective of the community-dwelling population in the United States...
Effect of second-generation antidepressants on mania- and depression-related visits in adults with bipolar disorder: a retrospective studyAlex Z Fu
Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, OH, USA
Value Health 10:128-36. 2007..To assess the effect of second-generation antidepressants on mania-related and depression-related office visits for adults with bipolar disorder...
Racial and ethnic differences in preference-based health status measureAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA
Curr Med Res Opin 22:2439-48. 2006..To document the racial and ethnic differences in individuals' perception of their general health status assessed by preference-based measures...
Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderlyAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio 44195, USA
Med Care 45:472-6. 2007..Potentially inappropriate medication (PIM) use is a major source of drug-related problems in the elderly. Few studies have quantified the effect of PIM use on total healthcare expenditures in the United States...
Second-generation antidepressant discontinuation and depressive relapse in adult patients with bipolar depression: results of a retrospective database analysisAlex Z Fu
Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, Ohio 44195, and Division of Pharmaceutical Outcomes and Policy, University of North Carolina, Chapel Hill, USA
Clin Ther 28:979-89. 2006..To date, few postmarketing studies have addressed whether long-term prophylactic treatment with second-generation antidepressants (ADs) delays depressive episodes in patients with bipolar disorder...
Using an automated recruitment process to generate an unbiased study sample of multiple sclerosis patientsDeborah M Miller
Mellen Center for Treatment and Research in Multiple Sclerosis, Neurological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Telemed J E Health 16:63-8. 2010..The subjects were highly representative of the target population, indicating that there was little bias in our selection process despite a constantly changing pool of eligible individuals...
Defining the optimal treatment for clinical stage I nonseminomatous germ cell testicular cancer using decision analysisCarvell T Nguyen
Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Ave, Desk Q10, Cleveland OH, 44195 0001, USA
J Clin Oncol 28:119-25. 2010..Surveillance was the preferred intervention for all except those patients at high risk for relapse...
A Decision analysis to determine the appropriate treatment for low-risk myelodysplastic syndromesMikkael A Sekeres
Department of Hematologic Oncology and Blood Disorders, Taussig Cancer Center, Cleveland Clinic, Cleveland, Ohio 44195, USA
Cancer 109:1125-32. 2007..For low-risk MDS the optimal initial therapy (GF vs nongrowth factor [NGF] therapies, including differentiation and immunomodulatory agents) based on response rates to NGF and GF and survival, has not been defined...
Web-based self-management for patients with multiple sclerosis: a practical, randomized trialDeborah M Miller
Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, Ohio 44195, USA
Telemed J E Health 17:5-13. 2011....
Cost effectiveness analysis of a hypertension management program in patients with type 2 diabetesDavid Ly
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA
J Clin Hypertens (Greenwich) 11:116-24. 2009..The HMP group achieved greater gains in quality-adjusted life-years and lower total health-related costs. As the time horizon increases, more money can be invested. HMPs can be a cost-effective and cost-neutral proposition...
Inappropriate medication use and health outcomes in the elderlyAlex Z Fu
Division of Pharmaceutical Policy and Evaluative Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NS 27599, USA
J Am Geriatr Soc 52:1934-9. 2004..These findings lend partial support to the use of Beers criteria in assessing the quality of prescribing and the appropriateness of medication use in the elderly population...
Healthcare costs of atypical antipsychotic use for patients with bipolar disorder in a Medicaid programmeYing Qiu
Division of Pharmaceutical Outcomes and Policy, University of North Carolina School of Pharmacy, Chapel Hill, North Carolina, USA
Appl Health Econ Health Policy 8:167-77. 2010..Facing increasing budget pressure, third-party payers, such as state Medicaid programmes in the US, are demanding better understanding of the medical costs beyond atypical antipsychotic drug costs alone in treating bipolar disorder...
Use of nomograms for personalized decision-analytic recommendationsAlex Z Fu
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio 44195, USA
Med Decis Making 30:267-74. 2010....
Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemiaRachid Baz
Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio 44195, USA
Cancer 110:1752-9. 2007..Earlier clinical trials have yielded conflicting results and possibly a minor survival benefit, often offset by a longer hospitalization time...
Impact of weekend admissions on quality of care and outcomes in patients with acute myeloid leukemiaNelli Bejanyan
Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio 44195, USA
Cancer 116:3614-20. 2010..The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekdays and treated with induction chemotherapy...
Survival and predictors of outcome in patients with acute leukemia admitted to the intensive care unitSnehal G Thakkar
Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio 44195, USA
Cancer 112:2233-40. 2008..Predictors of outcome and rates of successful discharge have not been defined for patients with acute leukemia admitted to intensive care units (ICUs) in the US...
Efficacy of growth factors compared to other therapies for low-risk myelodysplastic syndromesAli Reza Golshayan
Department of Hematologic Oncology and Blood Disorders, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA
Br J Haematol 137:125-32. 2007..Decision tools need to be developed to determine which therapy to choose for patients with low-risk MDS...
Non-invasive testing for Helicobacter pylori in patients hospitalized with peptic ulcer hemorrhage: a cost-effectiveness analysisAshish Atreja
Digestive Diseases Institute, Cleveland Clinic, Cleveland, OH, USA
Dig Dis Sci 55:1356-63. 2010..However, compliance with screening remains suboptimal. The aim of this study was to determine if a simplified approach based on noninvasive screening is cost effective in PUH...
The cost-effectiveness of lamotrigine in the maintenance treatment of adults with bipolar I disorderNeill W Calvert
Fourth Hurdle Consulting Ltd, Holborn Tower, 137 144 High Holborn, London WC1V 6PL, UK
J Manag Care Pharm 12:322-30. 2006..no maintenance. (acute-only) treatment. A comparison with olanzapine was included as an indirect analysis following publication of data during the course of our research...
How well have practices followed guidelines in prescribing antihypertensive drugs: the role of health insuranceJennifer D Guo
Pharmaceutical Policy and Evaluative Sciences, University of North Carolina at Chapel Hill, 27599-7360, USA
Value Health 6:18-28. 2003..Given a popular public perception of HMOs being most cost conscious in providing health care, further research is needed to understand why prescribing patterns associated with HMOs have poorly followed the JNC recommendations...
Income productivity in China: on the role of healthGordon G Liu
Department of Health Economics and Management, Guanghua School of Management, Peking University, Beijing, China
J Health Econ 27:27-44. 2008..These findings could have important implications for health and economic policy-making aimed at reducing the long-standing urban-rural economic gap and more comprehensively insuring the rural population against health and economic risk...
