Research Topics
| Thomas W FrazierSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorderThomas W Frazier
Department of Psychology, Case Western Reserve University, Cleveland, OH 44195, USA
Neuropsychology 18:543-55. 2004..These findings indicate that overall cognitive ability is significantly lower among persons with ADHD and that FSIQ may show as large a difference between ADHD and control participants as most other measures...- Relationships among victoria symptom validity test indices and personality assessment inventory validity scales in a large clinical sampleKathryn A Haggerty
Section of Neuropsychology, Department of Psychiatry and Psychology, Cleveland Clinic, Cleveland, OH 44195, USA
Clin Neuropsychol 21:917-28. 2007..These findings further suggest that measures of cognitive symptom validity only partially overlap with measures of psychopathological symptom exaggeration... 
Evaluation and comparison of psychometric instruments for pediatric bipolar spectrum disorders in four age groupsThomas W Frazier
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, OH, USA
J Child Adolesc Psychopharmacol 17:853-66. 2007..The CDRS-R may be better conceptualized as a two-factor measure in older adolescents. The semistructured K-SADS interview can be used to generate reliable diagnoses across a broad age range...- A two-year longitudinal MRI study of the corpus callosum in autismThomas W Frazier
Center for Autism CRS10 and Pediatric Behavioral Health, Cleveland Clinic, 2801 Martin Luther King Jr Drive, Cleveland, OH 44104, USA
J Autism Dev Disord 42:2312-22. 2012..Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions... 
Prevalence and correlates of psychotropic medication use in adolescents with an autism spectrum disorder with and without caregiver-reported attention-deficit/hyperactivity disorderThomas W Frazier
Center for Autism and Center for Pediatric Behavioral Health, The Cleveland Clinic, Cleveland, Ohio 44195, USA
J Child Adolesc Psychopharmacol 21:571-9. 2011..Correlates of medication use were also examined...- Detection of simulated ADHD and reading disorder using symptom validity measuresThomas W Frazier
The Cleveland Clinic, Center for Pediatric Behavioral Health CR11, 2801 Martin Luther King Jr Drive, Cleveland, OH 44104, USA
Arch Clin Neuropsychol 23:501-9. 2008..Percentages of control participants and participants in simulation conditions scoring below a specified cut score are provided to give clinicians an estimate of the simulator (true) positive and control (false) positive rates... - Relationship of persistent manic symptoms to the diagnosis of pediatric bipolar spectrum disordersThomas W Frazier
Center for Pediatric Behavioral Health and Center for Autism, Cleveland Clinic, 2801 Martin Luther King Jr Drive, Cleveland, OH 44104, USA
J Clin Psychiatry 72:846-53. 2011..The present study evaluated the possibility that the presence of persistent manic symptoms over a relatively short interval may increase the probability of a BPSD DSM diagnosis... - A meta-analysis of the corpus callosum in autismThomas W Frazier
Center for Autism and Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, Ohio 44195, USA
Biol Psychiatry 66:935-41. 2009..However, studies have differed concerning the magnitude and/or region contributing to CC reductions. The present study determined the significance and magnitude of reductions in CC total and regional area measures in autism... - Exploratory and confirmatory factor analysis of the autism diagnostic interview-revisedThomas W Frazier
Section of Behavioral Medicine, Children s Hospital for Rehabilitation, The Cleveland Clinic, Shaker Campus CR11, Cleveland, OH 44104, USA
J Autism Dev Disord 38:474-80. 2008..These findings indicate that the current ADI-R structure be revised to more accurately reflect the relationships between sub-scales... - Autism spectrum disorders as a qualitatively distinct category from typical behavior in a large, clinically ascertained sampleThomas W Frazier
The Cleveland Clinic, OH 44195, USA
Assessment 17:308-20. 2010..The identified category was associated with external indicators of disability, supporting its validity. Results indicated that ASD is best characterized as a category, distinct from typical behavior within ASD-affected families... - Effectiveness of medication combined with intensive behavioral intervention for reducing aggression in youth with autism spectrum disorderThomas W Frazier
Center for Autism, The Cleveland Clinic, Cleveland, Ohio 44195, USA
J Child Adolesc Psychopharmacol 20:167-77. 2010..There are no studies examining the combined effectiveness of antipsychotic medications and intensive behavioral intervention (IBI) to treat aggression in ASD... - The latent structure of cognitive symptom exaggeration on the Victoria Symptom Validity TestThomas W Frazier
Section of Behavioral Medicine, The Cleveland Clinic, Cleveland, OH 44104, USA
Arch Clin Neuropsychol 22:197-211. 2007..13-.14 in the present sample. Likelihood ratios are presented to assist clinical detection of individuals exhibiting the category of cognitive symptom exaggeration... - ADHD and achievement: meta-analysis of the child, adolescent, and adult literatures and a concomitant study with college studentsThomas W Frazier
Section of Behavioral Medicine, The Cleveland Clinic, Shaker Medical Campus, OH 44104, USA
J Learn Disabil 40:49-65. 2007..However, unlike earlier studies with children and adolescents, student ratings were as predictive as parent ratings. Findings are discussed in terms of the impact of moderator variables on ADHD and achievement... - The latent structure of attention-deficit/hyperactivity disorder in a clinic-referred sampleThomas W Frazier
Department of Psychiatry and Psychology, Section of Neuropsychology, The Cleveland Clinic, Cleveland, OH 44195, USA
Neuropsychology 21:45-64. 2007..Alternatively, the null findings may have resulted from inadequate indicator selection. A dimensional model may better facilitate accurate identification of individuals at risk for functional impairment... - Time course and predictors of health-related quality of life improvement and medication satisfaction in children diagnosed with attention-deficit/hyperactivity disorder treated with the methylphenidate transdermal systemThomas W Frazier
Center for Pediatric Behavioral Health and Center for Autism Children s Hospital, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Child Adolesc Psychopharmacol 20:355-64. 2010.... - Validation of proposed DSM-5 criteria for autism spectrum disorderThomas W Frazier
Center for Pediatric Behavioral Health and Center for Autism, Cleveland Clinic, OH, USA
J Am Acad Child Adolesc Psychiatry 51:28-40.e3. 2012..The primary aim of the present study was to evaluate the validity of proposed DSM-5 criteria for autism spectrum disorder (ASD)... - What differentiates children visiting outpatient mental health services with bipolar spectrum disorder from children with other psychiatric diagnoses?Mary A Fristad
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
Bipolar Disord 14:497-506. 2012.... - Characteristics of children with elevated symptoms of mania: the Longitudinal Assessment of Manic Symptoms (LAMS) studyRobert L Findling
Department of Psychiatry, Division of Child and Adolescent Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
J Clin Psychiatry 71:1664-72. 2010..This article describes the initial demographic information, diagnostic and symptom prevalence, and medication exposure for the LAMS cohort that will be followed longitudinally... - Clinical characteristics of children receiving antipsychotic medicationRobert L Findling
University Hospitals Case Medical Center Case Western Reserve University, Cleveland, OH 44106, USA
J Child Adolesc Psychopharmacol 21:311-9. 2011..However, the only diagnoses associated with a greater likelihood of being treated with an antipsychotic were psychotic disorders or unmodified DSM-IV bipolar 1 disorder... - Pediatric bipolar spectrum disorder and ADHD: comparison and comorbidity in the LAMS clinical sampleL Eugene Arnold
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
Bipolar Disord 13:509-21. 2011..To compare attention-deficit hyperactivity disorder (ADHD), bipolar spectrum disorders (BPSDs), and comorbidity in the Longitudinal Assessment of Manic Symptoms (LAMS) study... - Double-blind, randomized, placebo-controlled long-term maintenance study of aripiprazole in children with bipolar disorderRobert L Findling
Department of Psychiatry, University Hospitals, Case Medical Center, Cleveland, OH 44106, USA
J Clin Psychiatry 73:57-63. 2012..This study evaluates the long-term efficacy of aripiprazole compared to placebo in children with bipolar disorders... - An open-label study of aripiprazole in children with a bipolar disorderRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 21:345-51. 2011..The purpose of this open-label study was to describe the effectiveness of aripiprazole (APZ) in the treatment of children with bipolar disorders suffering from manic symptomatology... - Multivariate neuropsychological prediction of seizure lateralization in temporal epilepsy surgical casesTherese A Keary
Department of Psychiatry and Psychology, Section of Neuropsychology, Cleveland Clinic, Cleveland, Ohio, U S A
Epilepsia 48:1438-46. 2007.... - Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, and the University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 68:781-8. 2007..To determine if divalproex sodium was superior to placebo in the treatment of symptomatic youths who suffer from a bipolar spectrum disorder and who also have a parent with a diagnosis of a bipolar illness... - HRQL and medication satisfaction in children with ADHD treated with the methylphenidate transdermal systemMichael Manos
Cleveland Clinic, Cleveland, OH, USA
Curr Med Res Opin 25:3001-10. 2009.... - Clinical utility of the Boston Naming Test in predicting ultimate side of surgery in patients with medically intractable temporal lobe epilepsy: A double cross-validation studyRobyn M Busch
Cleveland Clinic Epilepsy Center, Neurological Institute, 9500 Euclid Avenue, P57, Cleveland, OH 44195, USA
Epilepsia 50:1270-3. 2009..8% of the combined sample. These results further support the clinical utility of the BNT in predicting side of surgery... - Utility of the Boston naming test in predicting ultimate side of surgery in patients with medically intractable temporal lobe epilepsyRobyn M Busch
Department of Psychiatry and Psychology, Section of Neuropsychology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Epilepsia 46:1773-9. 2005..Despite wide and frequent use, few studies have examined the utility of confrontation naming tasks in individuals with temporal lobe epilepsy (TLE)... - Increasing the reliability of ipsative interpretations in neuropsychology: a comparison of reliable components analysis and other factor analytic methodsThomas W Frazier
Department of Psychology, Case Western Reserve University, Cleveland, Ohio, USA
J Int Neuropsychol Soc 10:578-89. 2004..These findings suggest that difference scores derived from orthogonal factor solutions, particularly RCA solutions, may improve reliability for clinical assessment purposes... - Evidence-based assessment of attention-deficit/hyperactivity disorder: using multiple sources of informationThomas W Frazier
Department of Psychiatry and Psychology, Section of Neuropsychology, Cleveland Clinic Foundation, John Carroll University, OH 44118, USA
J Am Acad Child Adolesc Psychiatry 45:614-20. 2006 - Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine modelJessica L Mester
Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Eur J Hum Genet 19:763-8. 2011..Clinicians should consider germline PTEN testing at an early point in the diagnostic work-up for patients with extreme macrocephaly... - Preliminary quantitative investigation of predictors of treatment non-adherence in pediatric transplantation: a brief reportShoshana Y Kahana
Center for the Promotion of Adherence and Self Management, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Childrens Hospital Medical Center, OH, USA
Pediatr Transplant 12:656-60. 2008..17, 95% CI = -0.15-0.49, n = 3) and donor source (mean d = 0.33, 95% CI = -0.10-0.76, n = 4) exhibited small, non-significant relationships with non-adherence. Limitations of the study are discussed as are future directions for research... - Psychometric adequacy and comparability of the short and full forms of the Personality Assessment InventoryThomas W Frazier
Department of Psychology, John Carroll University, University Heights, OH 44118, USA
Psychol Assess 18:324-33. 2006..However, low levels of reliability across less impaired ranges of the latent trait, diminished content coverage, and altered validity detection may limit the utility of some of the short form scales... - Developing a 10-item mania scale from the Parent General Behavior Inventory for children and adolescentsEric A Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, NC 27599 3270, USA
J Clin Psychiatry 69:831-9. 2008..The goal of the present study was to develop and validate a brief (10 item) instrument to assess mania in a large sample of outpatients presenting with a variety of different DSM-IV diagnoses, including frequent comorbid conditions...