Research Topics
| Samar FarhaSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Ventricular geometry, strain, and rotational mechanics in pulmonary hypertensionSarinya Puwanant
Department of Cardiovascular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
Circulation 121:259-66. 2010..We tested the hypothesis that right ventricular (RV) pressure overload affects RV function and further influences left ventricular (LV) geometry, which adversely affects LV twist mechanics and segmental function...
Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertensionSamar Farha
Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Respir Res 14:6. 2013....
Novel therapeutic approaches to preserve the right ventricleSamar Farha
Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Curr Heart Fail Rep 10:12-7. 2013..In this review, we summarize the differences between the RV and LV and focus on novel therapies that target the RV...
Effects of the menstrual cycle on lung function variables in women with asthmaSamar Farha
Respiratory Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Am J Respir Crit Care Med 180:304-10. 2009..One vital function modulated over the menstrual cycle in healthy women is gas transfer, and this has been related to angiogenesis and cyclic expansion of the pulmonary vascular bed...
Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalitiesSamar Farha
Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Blood 117:3485-93. 2011....
Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycleSamar Farha
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, OH, USA
J Appl Physiol 103:1789-95. 2007..These findings suggest that angiogenesis in the lungs may participate in the cyclic changes in gas transfer that occur over the menstrual cycle...
Mast cell number, phenotype, and function in human pulmonary arterial hypertensionSamar Farha
Respiratory Institute, Cleveland, Ohio, USA
Pulm Circ 2:220-8. 2012..These results suggest that mast cells might contribute to the pulmonary vascular pathologic processes underlying PAH. More studies are needed to confirm their potential contribution to the disease...
Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertensionKewal Asosingh
Pathobiology, Lerner Research Institute and Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Blood 120:1218-27. 2012..The results of the present study suggest a causal role for hematopoietic stem cell abnormalities in vascular injury, right ventricular hypertrophy, and morbidity associated with PAH...
Massive cerebrovascular infarct due to the catastrophic antiphospholipid syndrome in a patient with idiopathic thrombocytopenic purpuraAriel Modrykamien
Respiratory Institute, Cleveland Clinic, Cleveland Ohio 44195, USA
J Intensive Care Med 24:269-72. 2009..Prompt and aggressive treatment may prevent and actually resolve lethal complications caused by this devastating syndrome...
High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertensionIlka Decker
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA
Clin Transl Sci 4:253-8. 2011..This suggests that altered iron homeostasis influences disease progression and demonstrates the importance of closely monitoring iron status in PAH patients...
