Research Topics
| T FalconeSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
| Collaborators
|
Detail Information
Publications
Endoscopic management of uterine fibroids: an updateE Soto
Department of Obstetrics, Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, OH, USA
Minerva Ginecol 64:507-20. 2012..Adequate preoperative evaluation with careful selection of the best operative approach for each particular patient constitutes the basis of safe and effective surgery for the operative management of uterine myomas...
Vitrification of isolated mice blastomeres using a closed loading deviceAmr Kader
Center for Reproductive Medicine, Glickman Urological and Kidney Institute and Obstetrics and Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, Ohio, USA
Reprod Biol Endocrinol 7:17. 2009..Using a cryotip and propagation in microvolumes, isolated mice blastomeres were vitrified and warmed with 100% post-warming survival...
Morphology and function of cryopreserved whole ovine ovaries after heterotopic autotransplantationAnna T Grazul-Bilska
Obstetrics, Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, OH, USA
Reprod Biol Endocrinol 6:16. 2008....
Cryopreservation/transplantation of ovarian tissue and in vitro maturation of follicles and oocytes: challenges for fertility preservationAlex C Varghese
Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Ohio, USA
Reprod Biol Endocrinol 6:47. 2008..The scope of this article is to take a comprehensively look at the challenges still faced in order for these novel technologies to be routinely employed with the aim of successful fertility preservation...
Three-dimensional in vitro follicle growth: overview of culture models, biomaterials, design parameters and future directionsNina Desai
Department of OB GYN and Women s Health Institute, Cleveland Clinic Foundation, Cleveland Clinic Fertility Center, Cleveland, Ohio, USA
Reprod Biol Endocrinol 8:119. 2010..We also try to present an overview of outcomes with various biomaterials and animal models and also the limitations of the existing systems...
Minimally invasive management of uterine fibroidsTommaso Falcone
Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Curr Opin Obstet Gynecol 14:401-7. 2002..Many minimally invasive techniques have recently been introduced for the management of uterine fibroids. The purpose of this review is to analyse recent data for techniques that are used to manage uterine fibroids...
Hysterectomy for benign diseaseTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio 44195, USA
Obstet Gynecol 111:753-67. 2008..In our experience, previous cesarean delivery, large uterus, or request for removing the ovaries are not valid reasons for excluding vaginal hysterectomy as an approach...
Reproductive outcome after transplantation of ovarian tissue: a systematic reviewMohamed A Bedaiwy
Department of Gynecology and Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Hum Reprod 23:2709-17. 2008..We systematically reviewed reproductive function after OTT for fertility preservation in women at high risk of premature ovarian failure (POF)...
Minimally invasive surgery for mass lesionsTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Clin Obstet Gynecol 48:353-60. 2005
Robotic surgeryTommaso Falcone
Cleveland Clinic Foundation, Ohio 44195, USA
Clin Obstet Gynecol 46:37-43. 2003
Ovarian function preservation in the cancer patientTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 81:243-57. 2004..To review the clinical modalities that are available to women receiving potentially sterilizing cancer therapy...
The elusive diagnostic test for endometriosisTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland Ohio 44195, USA
Fertil Steril 80:886-8. 2003
Robotic-assisted laparoscopic microsurgical tubal anastomosis: a human pilot studyT Falcone
Minimally Invasive Surgery Center, Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Fertil Steril 73:1040-2. 2000..CONCLUSION(s): Robotic technology can be used safely to create laparoscopic microsurgical anastomoses with adequate patency rates. Robotic technology has the potential to make laparoscopic microsuturing easier...
Robotics in gynecologyTommaso Falcone
Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
Surg Clin North Am 83:1483-9, xii. 2003..The rapid evolution of robotics will likely allow for more widespread application in all surgical specialties in the future...
What the internist needs to know about infertilityT Falcone
Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 68:65-72; discussion 73. 2001..Some causes of infertility are associated with significant medical problems such as diabetes and abnormal lipids; these should be assessed and a long-term management plan implemented...
Clinical management of endometriosisTommaso Falcone
Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Obstet Gynecol 118:691-705. 2011..The technique used to safely and completely remove the disease is discussed. The specific areas of involvement include the pelvic side wall, the cul-de-sac, and bladder peritoneum...
Robotics in reproductive surgery: strengths and limitationsM Catenacci
Cleveland Clinic, Cleveland, OH, USA
Placenta 32:S232-7. 2011....
Reproductive organ transplantation: advances and controversiesMohamed A Bedaiwy
Department of Obstetrics Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio44195, USA
Fertil Steril 90:2031-55. 2008..To review the advances and controversies in the field of reproductive organ transplantation...
Restoration of ovarian function after autotransplantation of intact frozen-thawed sheep ovaries with microvascular anastomosisMohamed A Bedaiwy
Department of Obstetrics and Gynecology and Minimally Invasive Surgery Center, The Cleveland Clinic Foundation, Ohio 44195, USA
Fertil Steril 79:594-602. 2003..03). CONCLUSION(S): Transplantation of an intact frozen-thawed ovary is technically feasible. Using this approach, immediate restoration of vascular supply and ovarian hormonal functions is possible...
Full robotic assistance for laparoscopic tubal anastomosis: a case reportT Falcone
Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Ohio, USA
J Laparoendosc Adv Surg Tech A 9:107-13. 1999..The patient recovered uneventfully after surgery and was discharged within 24 h after the procedure. Laparoscopic microsurgical tubal anastomosis with full robotic assistance is feasible and safe in humans...
Effect of diethylstilbestrol on reproductive functionJ M Goldberg
Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Ohio 44195, USA
Fertil Steril 72:1-7. 1999..To review the effects of in utero exposure to diethylstilbestrol (DES) on müllerian development and subsequent reproductive function...
Laparoscopic surgery for endometriosisMichelle Catenacci
The Cleveland Clinic, Department of Obstetrics and Gynecology, 9500 Euclid Avenue, Cleveland, OH, USA
Clin Obstet Gynecol 52:351-61. 2009..For pelvic pain, surgery has been shown to improve symptoms although there is a significant placebo effect with surgery. Finally, hysterectomy can be offered to women who fail initial conservative surgery...
Post-menopausal endometriosis with inferior vena cava invasion requiring surgical managementR Flyckt
Department of Obstetrics, Gynecology and Women s Health, Cleveland Clinic, 9500 Euclid Ave, A81, Cleveland, OH 44195, USA
Hum Reprod 26:2709-12. 2011..Medical management with AIs can be attempted for extra-pelvic endometriosis status post hysterectomy; however, the efficacy in this setting is limited. Surgical management may be necessary for bulky or invasive disease...
Gross and histologic characteristics of laparoscopic injuries with four different energy sourcesP K Tulikangas
Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 75:806-10. 2001..To compare the gross and histologic effects of bipolar and monopolar cautery, ultrasonic scalpel, and CO(2) laser on porcine ureter, bladder, and rectum...
Assessment of laparoscopic injuries by three methodsP K Tulikangas
Minimally Invasive Surgery Center, The Cleveland Clinic Foundation, Ohio 44195, USA
Fertil Steril 76:817-9. 2001..To compare laparoscopic, gross, and fluorescent assessment of laparoscopic pelvic injuries...
Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markersS Gupta
Reproductive Research Center, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Minerva Ginecol 58:527-51. 2006..Potential new therapeutic agents include modulators, such as cytokine receptor blockers and angiogenic receptor blockers, presently used for treating endometriosis...
Catamenial epilepsy: pathophysiology, diagnosis, and managementNancy Foldvary-Schaefer
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Neurology 61:S2-15. 2003..Larger multicenter trials, as well as further investigation of the pathophysiology of the disorder, are needed to identify the most effective treatment for women with catamenial epilepsy...
Superovulation and intrauterine insemination in cases of treated mild pelvic diseaseM Singh
Center for Advanced Research in Human Reproduction and Infertility, Urological Institute and Department of Gynecology-Obstetrics, Cleveland Clinic Foundation, 9500 Euclid Avenue, A81, Cleveland, Ohio 44195, USA
J Assist Reprod Genet 18:26-9. 2001..However, SO/IUI still remains a reasonable option for both these groups prior to IVF-ET...
Varicocelectomy improves intrauterine insemination success rates in men with varicoceleJ A Daitch
Center for Advanced Research in Human Reproduction and Infertility, Urological Institute, Department of Gynecology-Obstetrics and Biostatistics, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Urol 165:1510-3. 2001..A functional factor not measured on routine semen analysis may affect pregnancy rates in this setting. Men should be screened for varicocele before intrauterine insemination is initiated for male factor infertility...
Robotically assisted laparoscopic hysterectomy and adnexal surgeryH Margossian
Minimally Invasive Surgery Center and Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, OH 44195, USA
J Laparoendosc Adv Surg Tech A 11:161-5. 2001..No complications occurred. No ureteral injuries were found on necropsy. CONCLUSION: Although designed for laparoscopic microsuturing, this robotic technology has the potential to be used for more complex gynecologic procedures...
Peritoneal fluid environment in endometriosis. Clinicopathological implicationsM A Bedaiwy
Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Minerva Ginecol 55:333-45. 2003....
Comparison of intrauterine and intracervical insemination with frozen donor sperm: a meta-analysisJ M Goldberg
Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Ohio 44915, USA
Fertil Steril 72:792-5. 1999..To determine whether artificial insemination with frozen donor sperm yielded a higher pregnancy rate per cycle by intracervical (ICI) or intrauterine (IUI) techniques. A meta-analysis was performed...
Hormones and seizuresNancy Foldvary-Schaefer
Department of Neurology, Section of Epilepsy, The Cleveland Clinic Foundation, 9500 Euclid Avenue, S51, Cleveland, OH 44195, USA
Cleve Clin J Med 71:S11-8. 2004..It is important for the physician to work closely with the patient to determine whether her seizures are indeed catamenial and to design an appropriate treatment plan...
Robotic-assisted laparoendoscopic single-site surgery in gynecology: initial report and techniquePedro F Escobar
Department of Obstetrics and Gynecology and Women s Health Institute, Section of Gynecologic Oncology, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Minim Invasive Gynecol 16:589-91. 2009..We present our initial clinical experience and technique with robotic-assisted single-port surgery in gynecology...
Incidence of lower urinary tract injury at the time of total laparoscopic hysterectomyJ Eric Jelovsek
Cleveland Clinic, Section of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, Cleveland, OH 44195, USA
JSLS 11:422-7. 2007..To determine the incidence of and risk factors for injury to the lower urinary tract during total laparoscopic hysterectomy...
Fertility preservation and pregnancy outcome after malignancyTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Curr Opin Obstet Gynecol 17:21-6. 2005..This article discusses the mechanisms of reproductive failure after cancer therapy and the currently available fertility preservation strategies...
Tubal anastomosis by robotic compared with outpatient minilaparotomyAllison K Rodgers
Departments of Obstetrics and Gynecology, The Cleveland Clinic, Cleveland, Ohio 44159, USA
Obstet Gynecol 109:1375-80. 2007..To compare tubal anastomosis by robotic system compared with outpatient minilaparotomy...
Association between time from endometriosis surgery and outcome of in vitro fertilization cyclesMohamed A Bedaiwy
Minimally Invasive Surgery Center, Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Ohio 44195, USA
J Reprod Med 53:161-5. 2008..To evaluate the effect of time from surgery on the outcome of subsequent in vitro fertilization (IVF) cycles in endometriosis patients...
How should we advise patients about the contraceptive patch, given the FDA warning?Holly L Thacker
Women s Health Center at The Gault Women s Health and Breast Pavilion, Department of General Internal Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 73:45-7. 2006
Anatomy of ilioinguinal and iliohypogastric nerves in relation to trocar placement and low transverse incisionsJames L Whiteside
Department of Gynecology and Obstetrics A81, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Am J Obstet Gynecol 189:1574-8; discussion 1578. 2003..The purpose of this study was to map the course of the ilioinguinal and iliohypogastric nerves...
Laparoscopy for adnexal masses in the second trimester of pregnancyKevin J Stepp
Department of Gynecology, Cleveland Clinic Foundation, A81, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Am Assoc Gynecol Laparosc 10:55-9. 2003....
Clinical pregnancy and live births after transfer of embryos vitrified on day 3Nina Desai
Cleveland Clinic Fertility Center, Department of OB GYN and Women s Health Institute, Cleveland Clinic Foundation, 26900 Cedar Rd, Beachwood, OH 44122, USA
Reprod Biomed Online 20:808-13. 2010..A total of 78 infants have been born with no major congenital malformations. These data attest to the efficacy and safety of the vitrification technique for cryopreservation of human embryos at the 6- to 8-cell stage...
Laparoendoscopic single-site (LESS) surgery in patients with benign adnexal diseasePedro F Escobar
Department of OB GYN and Women s Health Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Fertil Steril 93:2074.e7-10. 2010..To present our initial experience in laparoscopic surgery for benign adnexal disease performed exclusively through an umbilical incision using a single three-channel port and flexible laparoscopic instrumentation...
Total antioxidant capacity and reactive oxygen species in amniotic fluidJanet M Burlingame
Department of Obstetrics and Gynecology and The Collaborative Biostatistics Center, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Obstet Gynecol 101:756-61. 2003....
Endometriosis-induced alterations in mouse metaphase II oocyte microtubules and chromosomal alignment: a possible cause of infertilityGihan Mansour
Ob Gyn and Women s Health Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 94:1894-9. 2010..To examine the effect of peritoneal fluid (PF) of patients with endometriosis on the cytoskeleton of metaphase II oocytes and correlate the results with the stage of endometriosis and the duration of infertility...
Vitrification of mouse embryo-derived ICM cells: a tool for preserving embryonic stem cell potential?Nina Desai
Department of Ob Gyn, Cleveland Clinic Foundation, Women s Health Institute, Beachwood, OH, USA
J Assist Reprod Genet 28:93-9. 2011..Vitrification technology presents new opportunities for preservation of embryo derived stem cells without first establishing a viable ESC line. This study tests the feasibility of cryopreserving ICM cells using vitrification...
A simple and efficient method for preparation of isolated ovarian follicles for transmission electron microscopyNina Desai
Department of Ob Gyn, Women s Health Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
J Assist Reprod Genet 27:97-101. 2010..A simple method for preparation of isolated ovarian follicles for transmission electron microscopy (TEM) using transwell inserts is described...
Endometriosis: still tough to diagnose and treatMarjan Attaran
Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Ohio 44195, USA
Cleve Clin J Med 69:647-53. 2002..The following review will familiarize the practicing physician with available therapies to maintain and enhance reproductive potential and control pelvic pain in women with endometriosis...
Evaluation of a novel single-port robotic platform in the cadaver model for the performance of various procedures in gynecologic oncologyPedro F Escobar
Department of Obstetrics and Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, OH 44195
Gynecol Oncol 120:380-4. 2011..The purpose of this protocol was to evaluate the feasibility and reproducibility of a dedicated da Vinci® single-port robotic platform in cadavers for the performance of various gynecologic oncology procedures...
In vitro fertilization updateJeffrey M Goldberg
Head, Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cleveland Clinic, OH 44195, USA
Cleve Clin J Med 74:329-38. 2007..We provide an overview of the current and experimental assisted reproductive technology techniques...
Laparoscopic repair of ureteral injuriesHarout Margossian
Department of Obstetrics and Gynecology, Lutheran Medical Center, Brooklyn, New York, USA
J Am Assoc Gynecol Laparosc 10:373-7. 2003..CONCLUSION: Ureterolysis may interfere with the healing process of ureteral injuries by increasing fibrosis and adventitial scarring. Laparoscopic repair of these injuries is feasible and safe...
Endometriosis-related pelvic pain: what is the evidence?James L Whiteside
Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Clin Obstet Gynecol 46:824-30. 2003
Laparoscopic microsurgical tubal anastomosis with and without robotic assistanceJeffrey M Goldberg
Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
Hum Reprod 18:145-7. 2003..The purpose of this study was to compare the duration of the procedure and hospitalization, blood loss and clinical outcomes for laparoscopic microsurgical tubal anastomosis performed with and without robotic assistance...
Endoscopic management of endometriosisC C G Chen
Cleveland Clinic, Cleveland, OH, USA
Minerva Ginecol 58:347-60. 2006..Excision of deeper lesions of the bladder and ureter require resection. This can be accomplished laparoscopically but requires experience with laparoscopic suturing...
Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trialM A Bedaiwy
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Hum Reprod 17:426-31. 2002..Before these markers can be used as a non-surgical diagnostic tool, these data should be verified in a larger study...
Endometriosis: a critical appraisal of the advances and the controversies of a challenging health problemM A Bedaiwy
Department of Obstetric and Women s Health Institute, Cleveland Clinic, Cleveland, OH, USA
Minerva Ginecol 61:285-98. 2009..Prospective randomiazed controlled trials proved that surgical treatment of endometriosis is better than placebo for endometriosis related pain and infertility for patients with stage I and II disease...
Robotics in gynecologic surgeryA C Frick
Obstetrics, Gynecology and Women s Health Institute, The Cleveland Clinic, Cleveland, OH 44195, USA
Minerva Ginecol 61:187-99. 2009..However, further research is warranted to better evaluate the relative benefits and costs of robotic assisted gynecologic surgery...
Surgical treatment of endometriosis: a 7-year follow-up on the requirement for further surgeryKhashayar Shakiba
Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio 44159, USA
Obstet Gynecol 111:1285-92. 2008..To investigate the need for further surgery after laparoscopic excision of endometriosis or hysterectomy...
Harvesting and autotransplantation of vascularized ovarian grafts: approaches and techniquesMohamed A Bedaiwy
Minimally Invasive Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Reprod Biomed Online 14:360-71. 2007..The inferior epigastric vessel is probably the most suitable heterotopic vascularizing vessel. End-to-end anastomosis yields the highest patency rate of vascularized grafts...
Differential growth of human embryos in vitro: role of reactive oxygen speciesMohamed A Bedaiwy
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Fertil Steril 82:593-600. 2004..Differential growth of ICSI embryos incubated under identical conditions may be in part due to differences in ROS levels of the culture medium surrounding these embryos...
Heterotopic autotransplantation of the ovary with microvascular anastomosis: a novel surgical techniqueElisabeth Jeremias
Department of Obstetrics and Gynecology, Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 77:1278-82. 2002..1 +/- 1). CONCLUSION(S): In conjunction with improved protocols for cryopreservation, ovarian autotransplantation with vascular anastomosis may be superior to current ovarian tissue banking and grafting techniques...
Robotic gynecologic surgery: past, present, and futureChi Chiung Grace Chen
Female Pelvic Medicine and Reconstructive Surgery, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
Clin Obstet Gynecol 52:335-43. 2009..Disadvantages include the learning curve associated with learning a new surgical technique and the equipment and operating costs of the robot and of using the robot...
Mouse blastocyst previtrification interventions and DNA integrityAmr Kader
Center for Reproductive Medicine, Glickman Urological and Kidney Institute, and Obstetrics and Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 93:1518-25. 2010..To assess the effect of implementing different previtrification interventions on the postwarming DNA integrity of vitrified blastocysts...
Evaluation of post-thaw DNA integrity of mouse blastocysts after ultrarapid and slow freezingAmr Kader
Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Fertil Steril 91:2087-94. 2009..To evaluate the effect of vitrification and two other methods of slow cryopreservation on DNA integrity in expanded and nonexpanded blastocysts...
The effect of endometriosis on in vitro fertilization outcomeM Catenacci
Department of Obstetrics and Gynecology, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44159, USA
Minerva Ginecol 60:209-21. 2008..Treatment options for women seeking pregnancy include surgical removal and/or in vitro fertilization. The aim of this study was to review current literature on the pathogenesis of endometriosis and treatment options for infertility...
Effect of varying equilibration time in a two-step vitrification method on the post-warming DNA integrity of mouse blastocystsAmr Kader
Center for Reproductive Medicine, Glickman Urological and Kidney Institute, and Obstetrics and Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Fertil Steril 93:2640-5. 2010..To assess the effect of equilibration time on the DNA integrity of vitrified-warmed mouse blastocysts...
Peritoneal fluid leptin is associated with chronic pelvic pain but not infertility in endometriosis patientsMohamed A Bedaiwy
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Department of Obstetrics Gynecology, Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Hum Reprod 21:788-91. 2006..The objective of this study was to evaluate the peritoneal fluid levels of leptin in patients with endometriosis and idiopathic infertility and compare them with a control group of tubal ligation/reanastomosis patients...
Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertilityXia Wang
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Department of Obsterics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 80:531-5. 2003..A positive relationship exists between increased sperm damage by ROS and higher levels of cytochrome c and caspases 9 and 3, which indicate positive apoptosis in patients with male factor infertility...
Cryopreservation of intact human ovary with its vascular pedicleMohamed A Bedaiwy
Department of Obstetrics and Gynecology, Minimally Invasive Surgery Center, The Cleveland Clinic Foundation, Cleveland, OH, USA
Hum Reprod 21:3258-69. 2006..Cryopreservation injury is associated neither with significant alteration in the expression pattern of Bcl-2 and p53 proteins in the ovarian tissues nor with significant follicular damage...
Assessment of tissue injury in cryopreserved ovarian tissueElisabeth Jeremias
Department of Obstetrics and Gynecology, Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Ohio 44195, USA
Fertil Steril 79:651-3. 2003
Alterations in mitochondria membrane potential and oxidative stress in infertile men: a prospective observational studyXia Wang
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 80:844-50. 2003..45). CONCLUSION(S): Measuring MMP in spermatozoa provides useful information about a man's fertility potential. Increased ROS production by spermatozoa is associated with a decreased MMP...
Protein supplementation and the incidence of apoptosis and oxidative stress in mouse embryosNavid Esfandiari
Department of Obstetrics and Gynecology, Glickman Urological Institute, Cleveland, Ohio 44195, USA
Obstet Gynecol 105:653-60. 2005..68 and 5.81 +/- 1.11, respectively, P = .001). CONCLUSION: Protein supplementation of culture media improves the hatching rate and reduces reactive oxygen species levels and the incidence of apoptosis in mouse preimplantation embryos...
Ovarian tissue banking for cancer patients: reduction of post-transplantation ischaemic injury: intact ovary freezing and transplantationMohamed A Bedaiwy
Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, A81, Cleveland, Ohio, USA
Hum Reprod 19:1242-4. 2004..Research in the development of technology to cryopreserve whole organs as well surgical techniques for the auto-transplantation of an ovary with its vascular pedicle should be encouraged...
Relationship of reactive oxygen species levels in day 3 culture media to the outcome of in vitro fertilization/intracytoplasmic sperm injection cyclesMohamed A Bedaiwy
Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44195, USA
Fertil Steril 94:2037-42. 2010..To examine the relationship of early human embryonic development parameters to day 3 reactive oxygen species (D-3 ROS) levels in culture media...
Robotically assisted gynaecological surgeryTommaso Falcone
Cleveland Clinic Foundation, Cleveland, Ohio, USA
Hum Fertil (Camb) 5:72-4. 2002..Future clinical trials will assess whether other gynaecological procedures can be performed with robotic assistance...
L-carnitine supplementation reduces oocyte cytoskeleton damage and embryo apoptosis induced by incubation in peritoneal fluid from patients with endometriosisGihan Mansour
Reproductive Research Center, Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio, USA
Fertil Steril 91:2079-86. 2009..To investigate the protective effect of L-carnitine (LC) against deleterious substances present in the peritoneal fluid (PF) of patients with endometriosis, which may affect the oocyte cytoskeleton and embryogenesis...
Vaginal extraction of the intact specimen following laparoscopic radical nephrectomyInderbir S Gill
Section of Laparoscopic and Minimally Invasive Surgery, Urological Institute, A-100, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
J Urol 167:238-41. 2002..It has now become our preferred technique of intact specimen extraction in appropriate female patients...
Differential expression of follicular fluid cytokines: relationship to subsequent pregnancy in IVF cyclesMohamed Bedaiwy
Reproductive Research Centre, Department of Obstetrics Gynaecology and Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Reprod Biomed Online 15:321-5. 2007..0002). Higher concentrations of IL-12 and lower concentrations of IL-6 in the peri-ovulatory FF are associated with a negative outcome in IVF treatment. Interleukins-12 and IL-6 are biological markers that appear to affect IVF outcome...
Laparoscopic robotic gynecologic surgeryArnold P Advincula
Department of Obstetrics and Gynecology, University of Michigan Medical Center, L 4000 Women's Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Obstet Gynecol Clin North Am 31:599-609, ix-x. 2004..The field of surgical robotics is evolving at an ever increasing pace, however, and gynecologists need to participate in its development...
Treatment strategies for endometriosisAllison K Rodgers
Department of Obstetrics and Gynecology, The Cleveland Clinic, Department of Obstetrics and Gynecology A81, 9500 Euclid Avenue, Cleveland, Ohio 44159, USA
Expert Opin Pharmacother 9:243-55. 2008..The presentation and physical appearance of endometriosis is extremely variable and can be characterized by a chronic intraperitoneal inflammatory process and adhesions. The only definitive diagnostic technique is laparoscopy...
Tumour necrosis factor-alpha blockers: potential limitations in the management of advanced endometriosis? A case reportKhashayar Shakiba
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Hum Reprod 21:2417-20. 2006..This also could explain why suppression of TNF-alpha showed no effect on infertility. However, use of TNF-alpha-blockers before IVF might increase the success rate in advanced endometriosis...
Role of total antioxidant capacity in the differential growth of human embryos in vitroMohamed Bedaiwy
Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Fertil Steril 86:304-9. 2006..Decreased embryonic fragmentation, enhanced cleavage rate, and increased blastocyst development rate may be partially related to day 1 TAC in the culture media. Whether this relationship is a cause or effect needs further assessment...
The impact of peritoneal fluid from healthy women and from women with endometriosis on sperm DNA and its relationship to the sperm deformity indexGihan Mansour
Obstetrics and Gynecology and Women s Health Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Fertil Steril 92:61-7. 2009..To study the effect of peritoneal fluid (PF) from healthy women and from women with endometriosis on sperm DNA and its relationship to sperm morphology as assessed by the sperm deformity index (SDI)...
Evidence of 'genuine empty follicles' in follicular aspirate: a case reportN Desai
Cleveland Clinic Foundation, Department of Ob Gyn, 26900 Cedar Road, Beachwood, OH 44122, USA
Hum Reprod 24:1171-5. 2009..We speculate that this may be the first actual evidence to support the existence of true empty follicles, which if left to grow in vivo might lead to empty graffian follicles and genuine EFS...
Laparoscopic repair of ureteral injuriesP K Tulikangas
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Am Assoc Gynecol Laparosc 8:259-62. 2001..CONCLUSION: Laparoscopic ureteroureterostomy is feasible in some cases of ureteral injury. Experience with laparoscopic suturing is necessary to perform this procedure...
Effect of ovarian involvement on peritoneal fluid cytokine concentrations in endometriosis patientsMohamed Ali Bedaiwy
Reproductive Research Center, Cleveland Clinic, Cleveland, OH 44195, USA
Reprod Biomed Online 14:620-5. 2007..Ovarian involvement does not alter the pattern of cytokines. It appears that the inflammatory mediators of endometriosis are similar with and without ovarian involvement...
Laparoscopy in the second trimester of pregnancyKevin Stepp
Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, A81, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Obstet Gynecol Clin North Am 31:485-96, vii. 2004..Strategies to reduce the risk of complications while performing laparoscopy on a pregnant patient are discussed...
Robotics in reproductive medicineJulie Sroga
Department of Obstetrics and Gynecology at the Ohio State University, 1654 Upham Drive, Means Hall 567 Columbus, Ohio 43210, USA
Front Biosci 13:1308-17. 2008..As robotic assisted surgery has emerged, this technology provides a feasible option for minimally invasive surgery, impacts surgical education, and plays a role in telepresence surgery...
Laparoscopic radical cystectomy in the femaleAlireza Moinzadeh
Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute and Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Urol 173:1912-7. 2005..Additionally, perioperative and short-term oncological outcome data are presented...
Genetic polymorphism in the fibrinolytic system and endometriosisMohamed A Bedaiwy
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Toronto, Ontario, Canada
Obstet Gynecol 108:162-8. 2006..The objective of this study was to evaluate PAI-1 genotypes in a group of women with or without endometriosis...
The impact of morbid obesity, pneumoperitoneum, and posture on respiratory system mechanics and oxygenation during laparoscopyJuraj Sprung
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesth Analg 94:1345-50. 2002..IMPLICATIONS: Morbid obesity significantly decreases respiratory system compliance and increases inspiratory resistance. Increased body weight, and not altered mechanics of breathing, was associated with worse PaO(2) during laparoscopy...
Analysis of apoptotic cell death, Bcl-2, and p53 protein expression in freshly fixed and cryopreserved ovarian tissue after exposure to warm ischemiaMahmoud R Hussein
Department of Pathology, Assiut University School of Medicine, Assiut, Egypt
Fertil Steril 85:1082-92. 2006..To evaluate the effect of ischemia time on the expression of Bcl-2 and p53 proteins on freshly fixed and cryopreserved-thawed ovarian tissue...
Effects of temperature on sperm motion characteristics and reactive oxygen speciesNavid Esfandiari
Center for Advanced Research in Human Reproduction Infertility, and Sexual Function, Urological Institute, and Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Int J Fertil Womens Med 47:227-33. 2002..CONCLUSION: Based on our results, we suggest that semen samples be stored at 37 degrees C after collection and during transportation and processing...
Vitamin C and vitamin E supplementation reduce oxidative stress-induced embryo toxicity and improve the blastocyst development rateXia Wang
Department of Obstetrics and Gynecology, Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Cleveland, Ohio 44195, USA
Fertil Steril 78:1272-7. 2002..Exposure of mouse embryos to ROS for extended periods results in embryotoxicity. Vitamin C is more effective than vitamin E in reversing ROS-induced mouse embryo toxicity...
Laparoscopic resection of deep pelvic endometriosis with rectosigmoid involvementHans J Duepree
Department of Colorectal Surgery, and The Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
J Am Coll Surg 195:754-8. 2002....
Left upper quadrant cannula insertionPaul K Tulikangas
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington 06030, USA
Fertil Steril 79:411-2. 2003..To determine the safety and efficacy of primary left upper quadrant laparoscopic cannula insertion...
Preservation of fertility in the cancer patientTommaso Falcone
Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
MedGenMed 7:65. 2005
Reproductive implications of endoscopic third ventriculostomy for the treatment of hydrocephalusMohamed A Bedaiwy
Department of Obstetrics and Gynecology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA
Eur J Obstet Gynecol Reprod Biol 140:55-60. 2008..The objective of this study was to compare reproductive function after two neurosurgical procedures for treating non-neoplastic hydrocephalus; endoscopic third ventriculostomy (ETV) and ventriculo-peritoneal shunt (VP)...
The effects of tidal volume and respiratory rate on oxygenation and respiratory mechanics during laparoscopy in morbidly obese patientsJuraj Sprung
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
Anesth Analg 97:268-74, table of contents. 2003..During laparoscopy, arterial oxygenation is affected only by the patient's body weight. Increases in tidal volume or respiratory rate do not improve arterial oxygenation...
Robotics in reproductive medicineSejal P Dharia
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Alabama, USA
Fertil Steril 84:1-11. 2005..CONCLUSION(S): Robotic-assisted surgery is an emerging technology, which provides an alternative to traditional surgical techniques in reproductive medicine and may have a role in surgical education and telepresence surgery...
Cryopreservation of intact ovaries--size is a variable?Tommaso Falcone
Fertil Steril 83:1587; author reply 1588. 2005
