Research Topics
| Bijan EghtesadSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Technical considerations in liver transplantation: what a hepatologist needs to know (and every surgeon should practice)Bijan Eghtesad
Department of General Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Liver Transpl 11:861-71. 2005
Posttransplant lymphoproliferative disorders in liver transplantation: a 20-year experienceAshok Jain
Thomas E. Starzl Transplantation Institute, the Divisions of Transplantation Surgery and Transplantation Pathology, and the Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Ann Surg 236:429-36; discussion 436-7. 2002..While it is too early to assess the impact of new advances in prophylaxis, diagnosis, and treatment, such approaches are based on an increased knowledge of the pathophysiology of PTLD...
Immunosuppression in liver transplantation: beyond calcineurin inhibitorsJohn Fung
Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, 3459 Fifth Avenue, N755 MUH, Pittsburgh, PA 15213, USA
Liver Transpl 11:267-80. 2005..CNI-sparing protocols appear to be much more promising in balancing the early need for minimizing rejection while tapering doses and minimizing long-term toxicity...
Liver transplantation for severe intrahepatic noncirrhotic portal hypertensionAlyssa M Krasinskas
Departments of Pathology, University of Pittsburgh, PA, USA
Liver Transpl 11:627-34; discussion 610-1. 2005..Importantly, however, a diagnosis of cirrhosis is not required in this group of patients to qualify them for OLT, and these patients have good long-term graft function after OLT...
Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantationAshokkumar Jain
Department of Surgery, Transplant Division, Strong Memorial Hospital, University of Rochester, Rochester, NY 14642, USA
Transplantation 80:859-64. 2005..5% improvement at 1 year. Three patients developed renal failure. Six patients died in the follow-up period. Addition of MMF with reduced tacrolimus dose resulted in sustained improvement in renal function in 58% of patients...
Pretransplant survival is shorter in HIV-positive than HIV-negative subjects with end-stage liver diseaseMargaret V Ragni
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 4306, USA
Liver Transpl 11:1425-30. 2005..05. In conclusion, pretransplant survival appears shorter in HIV-positive OLTX candidates and is unrelated to severity of liver or HIV disease. Further study is warranted to determine risk factors for poorer pretransplant outcomes...
Immunosuppression for liver transplantation in HCV-infected patients: mechanism-based principlesBijan Eghtesad
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Liver Transpl 11:1343-52. 2005....
Preservation solutions in liver transplantation: what are the options?Bijan Eghtesad
Liver Transpl 12:196-8. 2006
MELD and prediction of post-liver transplantation survivalShahid Habib
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Liver Transpl 12:440-7. 2006..Pretransplant MELD scores correlate inversely with posttransplant survival. However, better prognostic models are needed that would provide an overall assessment of transplant benefit relative to the severity of hepatic dysfunction...
Using livers from donation after cardiac death donors--a proposal to protect the true Achilles heelJohn J Fung
Liver Transpl 13:1633-6. 2007
Triple-phase computed tomography and intraoperative flow measurements improve the management of portosystemic shunts during liver transplantationFederico N Aucejo
Departments of General Surgery and Radiology, Cleveland Clinic, Cleveland, OH 44195, USA
Liver Transpl 14:96-9. 2008..In conclusion, sustained good graft function and inflow were achieved in all 16 patients...
Association between donor-recipient serum sodium differences and orthotopic liver transplant graft functionJacek B Cywinski
Department of General Anesthesiology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH 44195, USA
Liver Transpl 14:59-65. 2008..02). The use of HTK preservation solution was associated with higher mean postoperative aspartate aminotransferase levels (P = 0.02) and decreased mean RBC (P < 0.001) and FFP usage (P = 0.009) compared to UW preservation solution use...
Severe hemolysis resulting from D incompatibility in a case of ABO-identical liver transplantMark K Fung
Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania, USA
Transfusion 44:1635-9. 2004..Approximately 10 percent of ABO-compatible liver transplants involve a D- donor and a D+ recipient...
Use of alemtuzumab and tacrolimus monotherapy for cadaveric liver transplantation: with particular reference to hepatitis C virusAmadeo Marcos
Thomas E. Starzl Transplantation Institute, Pittsburgh, Pennsylvania, USA
Transplantation 78:966-71. 2004..Lymphoid depletion with alemtuzumab and minimalistic maintenance immunosuppression is a practical strategy of liver transplantation in HCV recipients but not HCV recipients...
Liver transplantation in patients with HIV infectionJohn Fung
Department of Surgery, Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
Liver Transpl 10:S39-53. 2004..5. The degree of immunosuppression from iatrogenic drug therapy and HIV does not lead to increased risk of infectious complications...
Pregnancy after liver transplantation with tacrolimus immunosuppression: a single center's experience update at 13 yearsAshokkumar B Jain
Thomas E Starzl Transplantation Institute, Division of Transplantation, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Transplantation 76:827-32. 2003..Tacrolimus has been increasingly used in solid-organ transplantation, and the effect of the drug on pregnancy is still of interest to clinicians. This study updates our single-center experience...
Effect of coadministered lopinavir and ritonavir (Kaletra) on tacrolimus blood concentration in liver transplantation patientsAshokkumar B Jain
Department of Surgery, Division of Transplantation, Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
Liver Transpl 9:954-60. 2003..Great caution is required in the management of tacrolimus dosage when Kaletra is introduced or withdrawn in HIV-positive patients after liver transplantation, particularly in the presence of hepatic dysfunction...
Tolerogenic immunosuppression for organ transplantationThomas E Starzl
Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Lancet 361:1502-10. 2003..We aimed to apply these principles in recipients of renal and extrarenal organ transplants...
Liver transplantation in precirrhotic biliary tract disease: Portal hypertension is frequently associated with nodular regenerative hyperplasia and obliterative portal venopathySusan C Abraham
Department of Pathology and Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 30:1454-61. 2006..The occurrence of NRH in some patients transplanted for other indications suggests it is a histologic pattern that can precede the development of clinically significant portal hypertension...
Dental health status of liver transplant candidatesJames Guggenheimer
Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA
Liver Transpl 13:280-6. 2007..Edentulous patients should have periodic examinations for oral cancer...
Pancreatitis after liver transplantation in children: a single-center experienceBijan Eghtesad
The Thomas E Starzl Transplantation Institute and Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
Transplantation 75:190-3. 2003..We performed a retrospective review in a large cohort of pediatric liver transplant recipients at a single institution to define the impact of this problem in children...
Ribavirin dose modification based on renal function is necessary to reduce hemolysis in liver transplant patients with hepatitis C virus infectionAshok B Jain
Transplantation Institute, The Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
Liver Transpl 8:1007-13. 2002..Further pharmacokinetic studies of ribavirin in LTx patients with varying degrees of renal function may allow the development of an algorithm for the safer use of ribavirin in HCV-positive LTx patients...
Intrahepatic biliary anatomy of living adult liver donors: correlation of mangafodipir trisodium-enhanced MR cholangiography and intraoperative cholangiographyVibhu Kapoor
Department of Radiology, Division of Abdominal Imaging, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
AJR Am J Roentgenol 179:1281-6. 2002..Noninvasive preoperative evaluation of the biliary anatomy in donor candidates is important for the detection of common anatomic variants that may require alternative graft-harvesting surgery...
Cruveilhier-Baumgarten disease in a patient with Turner syndrome: case report of a rare indication for liver transplantationFederico Aucejo
Department of General Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
Liver Transpl 14:299-302. 2008..Liver transplantation to treat this condition overcomes portal hypertension and reconstitutes the diminished hepatic function due to severe atrophy of the portal venous inflow...
Pulmonary hypertension after liver transplantation in patients with antecedent hepatopulmonary syndrome: a report of 2 cases and review of the literatureFederico Aucejo
Departments of General Surgery, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA
Liver Transpl 12:1278-82. 2006..This experience calls for better understanding of the pathogenesis of HPS and PPHTN and ways to better predict their occurrence...
Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or small-for-size syndromeAnthony J Demetris
Department of Pathology, Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Surg Pathol 30:986-93. 2006..These findings suggest that portal hyperperfusion, venous pathology, and the arterial buffer response importantly contribute to early and late clinical and histopathologic manifestations of the small-for-size syndrome...
Isolated right hepatic vein obstruction after piggyback liver transplantationFederico Aucejo
Department of General Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Liver Transpl 12:808-12. 2006..In conclusion, all 3 patients developed recurrent ascites requiring angioplasty and/or stent placement across the right hepatic vein to alleviate the symptoms...
Expanding the donor pool: safe transplantation of a cadaveric liver allograft with a 10 cm cavernous hemangioma--a case reportFederico N Aucejo
Department of General Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Liver Transpl 12:687-9. 2006
Dental management of the (solid) organ transplant patientJames Guggenheimer
University of Pittsburgh School of Dental Medicine, 3501 Terrace St, Pittsburgh, PA 15261, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:383-9. 2003..This article reviews the current status of dental care practices that have been recommended and presents a rationale that can be applied as the basis for guidelines and recommendations for the treatment of the organ transplant patient...
Extended follow-up of extended right lobe living donors: when is enough enough?Bijan Eghtesad
Liver Transpl 12:199-200. 2006
Four-color flow cytometric analysis of peripheral blood donor cell chimerismDiana Metes
Department of Surgery, Thomas E. Starzl Tranplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
Hum Immunol 64:787-95. 2003..However, the detection of MHC-mismatched leukocytes of all lineages was much lower when frozen peripheral blood mononuclear cells were used...
Liver transplantation for growing teratoma syndrome: report of a caseBijan Eghtesad
Division of Transplantation Surgery, University of Pittsburgh, and the Thomas E. Starzl Transplantation Institute, Pittsburgh, PA 15213, USA
Liver Transpl 9:1222-4. 2003..We discuss his postoperative management, follow-up, and briefly review literature on the subject...
Diagnosis and treatment of intracardiac thrombosis during orthotopic liver transplantationRaymond M Planinsic
Director of Hepatic Transplantation Anesthesiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Room C 207, Pittsburgh, PA 15213, USA
Anesth Analg 99:353-6, table of contents. 2004..Transesophageal echocardiography was used to quickly diagnose the thrombus, allowing rapid pharmacological intervention and later guide surgical evacuation of the intracardiac thrombus via the inferior vena cava...
"Splenic artery steal syndrome" is a misnomer: the cause is portal hyperperfusion, not arterial siphonCristiano Quintini
Department of General Surgery, Liver Transplant Center, Cleveland, OH 44195, USA
Liver Transpl 14:374-9. 2008..6, 0.72, 0.86, and 0.68, in patients 1-4, respectively. SAE reduces excessive portal vein flow and thereby ameliorates an overactive HABR that can cause graft dysfunction and ultimately HA thrombosis...
