Christopher R Butson

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Predicting the effects of deep brain stimulation with diffusion tensor based electric field models
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Med Image Comput Comput Assist Interv 9:429-37. 2006
  2. pmc Experimental and theoretical characterization of the voltage distribution generated by deep brain stimulation
    Svjetlana Miocinovic
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Exp Neurol 216:166-76. 2009
  3. ncbi request reprint Random noise paradoxically improves light-intensity encoding in Hermissenda photoreceptor network
    Christopher R Butson
    Department of Biomedical Engineering, University of Utah, 20 S 2030 E, Salt Lake City, UT 84112 9458, USA
    J Neurophysiol 99:146-54. 2008
  4. pmc Patient-specific models of deep brain stimulation: influence of field model complexity on neural activation predictions
    Ashutosh Chaturvedi
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Stimul 3:65-7. 2010
  5. ncbi request reprint Subthalamic nucleus deep brain stimulation: accurate axonal threshold prediction with diffusion tensor based electric field models
    Ashutosh Chaturvedi
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1240-3. 2006
  6. ncbi request reprint Optimizing deep brain stimulation parameter selection with detailed models of the electrode-tissue interface
    Cameron C McIntyre
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Conf Proc IEEE Eng Med Biol Soc 1:893-5. 2006
  7. pmc Patient-specific analysis of the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA
    Neuroimage 34:661-70. 2007
  8. pmc Automated 3-dimensional brain atlas fitting to microelectrode recordings from deep brain stimulation surgeries
    J Luis Lujan
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Stereotact Funct Neurosurg 87:229-40. 2009
  9. pmc Current steering to control the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Stimul 1:7-15. 2008
  10. pmc Probabilistic analysis of activation volumes generated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Neuroimage 54:2096-104. 2011

Research Grants

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Predicting the effects of deep brain stimulation with diffusion tensor based electric field models
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Med Image Comput Comput Assist Interv 9:429-37. 2006
    ..In turn, the 3D tissue electrical properties of the brain play an important role in regulating the spread of neural activation generated by DBS...
  2. pmc Experimental and theoretical characterization of the voltage distribution generated by deep brain stimulation
    Svjetlana Miocinovic
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Exp Neurol 216:166-76. 2009
    ....
  3. ncbi request reprint Random noise paradoxically improves light-intensity encoding in Hermissenda photoreceptor network
    Christopher R Butson
    Department of Biomedical Engineering, University of Utah, 20 S 2030 E, Salt Lake City, UT 84112 9458, USA
    J Neurophysiol 99:146-54. 2008
    ..These results suggest that noise plays a constructive role in neural information processing, a concept that could have important implications for understanding neural information processing or designing neural interface devices...
  4. pmc Patient-specific models of deep brain stimulation: influence of field model complexity on neural activation predictions
    Ashutosh Chaturvedi
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Stimul 3:65-7. 2010
    ..Furthermore, the more simplistic neurostimulation models substantially overestimated the spatial extent of neural activation...
  5. ncbi request reprint Subthalamic nucleus deep brain stimulation: accurate axonal threshold prediction with diffusion tensor based electric field models
    Ashutosh Chaturvedi
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1240-3. 2006
    ..In addition, the simplifications and assumptions typically utilized in neurostimulation models substantially overestimate neural activation...
  6. ncbi request reprint Optimizing deep brain stimulation parameter selection with detailed models of the electrode-tissue interface
    Cameron C McIntyre
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    Conf Proc IEEE Eng Med Biol Soc 1:893-5. 2006
    ..The goals of the StimExplorer system are to educate clinicians on the impact of stimulation parameter manipulation, and improve the customization of DBS to individual patients...
  7. pmc Patient-specific analysis of the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA
    Neuroimage 34:661-70. 2007
    ....
  8. pmc Automated 3-dimensional brain atlas fitting to microelectrode recordings from deep brain stimulation surgeries
    J Luis Lujan
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Stereotact Funct Neurosurg 87:229-40. 2009
    ..We present an automated method for optimally fitting a 3-dimensional brain atlas to intraoperative MER and predicting a target DBS electrode location in stereotactic coordinates for the patient...
  9. pmc Current steering to control the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Stimul 1:7-15. 2008
    ....
  10. pmc Probabilistic analysis of activation volumes generated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Neuroimage 54:2096-104. 2011
    ..The results suggest that selection of both electrode placement and clinical stimulation parameter settings could be tailored to the patient's primary symptoms using patient-specific models and PSAs...
  11. ncbi request reprint Computational analysis of deep brain stimulation
    Cameron C McIntyre
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Expert Rev Med Devices 4:615-22. 2007
    ..We then provide a prospective view on the application of DBS-modeling tools to augment the clinical utility of DBS and to design the next generation of DBS technology...
  12. pmc Role of electrode design on the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH, USA
    J Neural Eng 3:1-8. 2006
    ..Therefore, it may be possible to improve therapeutic benefit and minimize side effects from DBS with the design of target-specific electrodes...
  13. ncbi request reprint Mechanisms of noise-induced improvement in light-intensity encoding in Hermissenda photoreceptor network
    Christopher R Butson
    Department of Biomedical Engineering, University of Utah, 20 S 2030 E, Salt Lake City, UT 84112 9458, USA
    J Neurophysiol 99:155-65. 2008
    ..The constructive role of noise in biological signal processing has implications both for understanding the dynamics of the nervous system and for the design of neural interface devices...
  14. ncbi request reprint Computational analysis of subthalamic nucleus and lenticular fasciculus activation during therapeutic deep brain stimulation
    Svjetlana Miocinovic
    Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Neurophysiol 96:1569-80. 2006
    ..Nonetheless, both neural targets may play important roles in the therapeutic mechanisms of STN DBS...
  15. pmc Differences among implanted pulse generator waveforms cause variations in the neural response to deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Avenue, ND20, Cleveland, OH 44195, USA
    Clin Neurophysiol 118:1889-94. 2007
    ..The goal of this study was to evaluate and compare the stimulation waveforms produced by each IPG model...
  16. pmc Sources and effects of electrode impedance during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Ave ND 20, Cleveland, OH 44195, USA
    Clin Neurophysiol 117:447-54. 2006
    ....
  17. pmc Tissue and electrode capacitance reduce neural activation volumes during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Avenue ND20, Cleveland, OH 44195, USA
    Clin Neurophysiol 116:2490-500. 2005
    ..In this study we evaluate the effects of the tissue and electrode capacitance on the volume of tissue activated (VTA) during deep brain stimulation (DBS)...

Research Grants1

  1. Realistic Biophysical Modeling of Deep Brain Stimulation
    CHRISTOPHER BUTSON; Fiscal Year: 2007
    ..This system has the potential to improve patient outcomes by improving target and trajectory selection, reducing time in surgery, and maximizing stimulation benefit while minimizing side effects. ..