Sorin J Brener

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. doi request reprint Comparison of percutaneous versus surgical revascularization of severe unprotected left main coronary stenosis in matched patients
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 101:169-72. 2008
  2. ncbi request reprint Adjunctive therapy for percutaneous revascularization in acute myocardial infarction
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Curr Pharm Des 10:399-405. 2004
  3. ncbi request reprint Propensity analysis of long-term survival after surgical or percutaneous revascularization in patients with multivessel coronary artery disease and high-risk features
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Desk F 25, Cleveland, Ohio 44195, USA
    Circulation 109:2290-5. 2004
  4. ncbi request reprint Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Circulation 110:994-8. 2004
  5. ncbi request reprint The relationship between baseline risk and mortality in ST-elevation acute myocardial infarction treated with pharmacological reperfusion: insights from the Global Utilization of Strategies To open Occluded arteries (GUSTO) V trial
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am Heart J 150:89-93. 2005
  6. ncbi request reprint Predictors of revascularization method and long-term outcome of percutaneous coronary intervention or repeat coronary bypass surgery in patients with multivessel coronary disease and previous coronary bypass surgery
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F 25, Cleveland, OH 44195 USA
    Eur Heart J 27:413-8. 2006
  7. ncbi request reprint Insights into the pathophysiology of ST-elevation myocardial infarction
    Sorin J Brener
    Angiography Core Laboratory, Interventional Cardiology Cleveland Clinic Foundation, Cleveland, OH, USA
    Am Heart J 151:S4-10. 2006
  8. ncbi request reprint Antihypertensive therapy and regression of coronary artery disease: insights from the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis (CAMELOT) and Norvasc for Regression of Manifest Atherosclerotic Lesions by Intravascular So
    Sorin J Brener
    Department of Cardiovascular Medicine and Biostatistics, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:1059-63. 2006
  9. ncbi request reprint Prolonged dual antiplatelet therapy after percutaneous coronary intervention reduces ischemic events without affecting the need for repeat revascularization: insights from the CREDO trial
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44122, USA
    J Invasive Cardiol 19:287-90. 2007
  10. ncbi request reprint Culprit-only or multivessel revascularization in patients with acute coronary syndromes: an American College of Cardiology National Cardiovascular Database Registry report
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Am Heart J 155:140-6. 2008

Detail Information

Publications41

  1. doi request reprint Comparison of percutaneous versus surgical revascularization of severe unprotected left main coronary stenosis in matched patients
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 101:169-72. 2008
    ..Diabetes mellitus and advanced co-morbidity were the principal determinants of survival. These findings support the need for randomized trials with adequate follow-up to compare the 2 approaches...
  2. ncbi request reprint Adjunctive therapy for percutaneous revascularization in acute myocardial infarction
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Curr Pharm Des 10:399-405. 2004
    ....
  3. ncbi request reprint Propensity analysis of long-term survival after surgical or percutaneous revascularization in patients with multivessel coronary artery disease and high-risk features
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Desk F 25, Cleveland, Ohio 44195, USA
    Circulation 109:2290-5. 2004
    ....
  4. ncbi request reprint Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Circulation 110:994-8. 2004
    ..Despite significant pharmacological and mechanical advancements in PCI, uncertainty remains about the optimal activated clotting time (ACT) for prevention of ischemic or hemorrhagic complications...
  5. ncbi request reprint The relationship between baseline risk and mortality in ST-elevation acute myocardial infarction treated with pharmacological reperfusion: insights from the Global Utilization of Strategies To open Occluded arteries (GUSTO) V trial
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am Heart J 150:89-93. 2005
    ....
  6. ncbi request reprint Predictors of revascularization method and long-term outcome of percutaneous coronary intervention or repeat coronary bypass surgery in patients with multivessel coronary disease and previous coronary bypass surgery
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F 25, Cleveland, OH 44195 USA
    Eur Heart J 27:413-8. 2006
    ..The optimal revascularization strategy in patients with symptomatic multivessel coronary artery disease (CAD) and previous coronary artery bypass grafting (CABG) remains unknown...
  7. ncbi request reprint Insights into the pathophysiology of ST-elevation myocardial infarction
    Sorin J Brener
    Angiography Core Laboratory, Interventional Cardiology Cleveland Clinic Foundation, Cleveland, OH, USA
    Am Heart J 151:S4-10. 2006
    ....
  8. ncbi request reprint Antihypertensive therapy and regression of coronary artery disease: insights from the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis (CAMELOT) and Norvasc for Regression of Manifest Atherosclerotic Lesions by Intravascular So
    Sorin J Brener
    Department of Cardiovascular Medicine and Biostatistics, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:1059-63. 2006
    ..We set out to explore the relationship between quantitative coronary angiography parameters, baseline characteristics, and clinical events in a large trial of CAD regression with antihypertensive agents...
  9. ncbi request reprint Prolonged dual antiplatelet therapy after percutaneous coronary intervention reduces ischemic events without affecting the need for repeat revascularization: insights from the CREDO trial
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44122, USA
    J Invasive Cardiol 19:287-90. 2007
    ..The relationship between target vessel revascularization (TVR) and ischemic events in patients treated with aspirin and clopidogrel or aspirin alone from 1 month to 1 year after PCI has not been studied...
  10. ncbi request reprint Culprit-only or multivessel revascularization in patients with acute coronary syndromes: an American College of Cardiology National Cardiovascular Database Registry report
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Am Heart J 155:140-6. 2008
    ..Although an early invasive strategy improves outcome in these patients, there are limited data on culprit-only, single-vessel (SV) percutaneous coronary intervention (PCI) or MV PCI in the NSTE ACS setting...
  11. ncbi request reprint Revisiting optimal anticoagulation with unfractionated heparin during coronary stent implantation
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 92:1468-71. 2003
    ..3%, 7.5%, 8.1%, and 7.1%, respectively (p=0.71). The incidence of bleeding complications was 6.6%, 5.9%, 6.9%, and 7.3%, respectively (p=0.81). ACT did not independently predict either ischemic or hemorrhagic complications...
  12. ncbi request reprint Eptifibatide and low-dose tissue plasminogen activator in acute myocardial infarction: the integrilin and low-dose thrombolysis in acute myocardial infarction (INTRO AMI) trial
    Sorin J Brener
    Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Coll Cardiol 39:377-86. 2002
    ..This study was designed to test the hypothesis that eptifibatide and reduced-dose tissue plasminogen activator (t-PA) will enhance infarct artery patency at 60 min in patients with acute myocardial infarction (AMI)...
  13. ncbi request reprint Efficacy and safety of multivessel percutaneous revascularization and tirofiban therapy in patients with acute coronary syndromes
    Sorin J Brener
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 90:631-3. 2002
  14. ncbi request reprint Abciximab-facilitated percutaneous coronary intervention and long-term survival--a prospective single-center registry
    Sorin J Brener
    Department of Cardiology, Cleveland Clinic Foundation, OH 44195, USA
    Eur Heart J 24:630-8. 2003
    ..To identify predictors of use of abciximab and evaluate the long-term survival after percutaneous coronary intervention with or without abciximab in a broad spectrum of patients...
  15. ncbi request reprint Association between CK-MB elevation after percutaneous or surgical revascularization and three-year mortality
    Sorin J Brener
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 40:1961-7. 2002
    ..The goal of this study was to assess the long-term impact of creatine kinase-MB isoform (CK-MB) elevation after percutaneous or surgical revascularization...
  16. ncbi request reprint A randomized multicenter trial comparing a new, low-pressure versus a conventional coronary stent: primary results from the CONSERVE trial
    Sorin J Brener
    The Cleveland Clinic Foundation, OH 44195, USA
    J Invasive Cardiol 15:128-32. 2003
    ..02). Thus, the new LP stent achieves rates of revascularization that are not inferior to the Guidant stent, but this effect cannot be linked to lower-pressure deployment...
  17. doi request reprint Comparison of drug-eluting stents versus bare-metal stents for treating ST-segment elevation myocardial infarction
    Mehdi H Shishehbor
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    JACC Cardiovasc Interv 1:227-32. 2008
    ..We sought to examine the clinical outcomes of patients treated with drug-eluting stents (DES) compared with bare-metal stents (BMS) during primary angioplasty for ST-segment elevation myocardial infarction (STEMI)...
  18. ncbi request reprint Prognostic significance of creatine kinase-MB elevation after percutaneous coronary intervention in patients with chronic renal dysfunction
    Allen Jeremias
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am Heart J 143:1040-5. 2002
    ..Because CK-MB is frequently elevated in renal disease even in the absence of myocardial injury, the clinical significance of CK-MB elevation after PCI in patients with renal insufficiency has been questioned...
  19. ncbi request reprint In unstable angina or non-ST-segment acute coronary syndrome, should patients with multivessel coronary artery disease undergo multivessel or culprit-only stenting?
    Mehdi H Shishehbor
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    J Am Coll Cardiol 49:849-54. 2007
    ....
  20. ncbi request reprint Real-world bare metal stenting: identification of patients at low or very low risk of 9-month coronary revascularization
    Stephen G Ellis
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Catheter Cardiovasc Interv 63:135-40. 2004
    ..Conversely, if the benefits of DESs are attenuated in routine practice, many groups of patients treated with BMSs may have nearly comparable results...
  21. ncbi request reprint Use of platelet glycoprotein IIb/IIIa inhibitors in saphenous vein graft percutaneous coronary intervention and clinical outcomes
    Juhana Karha
    The Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Cardiol 98:906-10. 2006
    ..92, 95% confidence interval 0.69 to 1.23, p = 0.59). In conclusion, adjunctive use of platelet GP IIb/IIIa inhibitors in saphenous vein graft PCI does not appear to be associated with less myonecrosis or improved survival...
  22. ncbi request reprint Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stent
    Juhana Karha
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Cardiol 98:616-8. 2006
    ..This finding was present in the BMS and SES groups and highlights the need for aggressive risk-factor modification after PCI...
  23. ncbi request reprint Safety of abciximab during percutaneous coronary intervention in patients with chronic renal insufficiency
    Allen Jeremias
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 89:1209-11. 2002
  24. doi request reprint Long-term impact of drug-eluting stents versus bare-metal stents on all-cause mortality
    Mehdi H Shishehbor
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 52:1041-8. 2008
    ..Our purpose was to examine the incidence of all-cause mortality among drug-eluting stents (DES) and bare-metal stents (BMS) while adjusting for many confounding factors generally not considered in prior studies...
  25. doi request reprint Reperfusion after primary angioplasty for ST-elevation myocardial infarction: predictors of success and relationship to clinical outcomes in the APEX-AMI angiographic study
    Sorin J Brener
    Cleveland Clinic Foundation, Cleveland, OH, USA
    Eur Heart J 29:1127-35. 2008
    ....
  26. doi request reprint Safety and efficacy of overlapping sirolimus-eluting versus paclitaxel-eluting stents
    Mehdi H Shishehbor
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Am Heart J 155:1075-80. 2008
    ..The short-term and long-term safety and efficacy of paclitaxel versus sirolimus-overlapping drug-eluting stents (DES) is unknown. We sought to examine the clinical consequences of overlapping sirolimus versus paclitaxel DES...
  27. ncbi request reprint GuardWire emboli protection device is associated with improved myocardial perfusion grade in saphenous vein graft intervention
    Jose E Exaire
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am Heart J 148:1003-6. 2004
    ..We sought to analyze TMP after SVG-PCI with and without EPD and determine its impact on inhospital MACE...
  28. ncbi request reprint Early invasive strategies for acute coronary syndromes
    Martin J Quinn
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Desk F25, 9500 Euclid Avenue, OH 44195, USA
    Curr Cardiol Rep 4:334-40. 2002
    ..Initial costs are higher with an early invasive strategy; however, these are offset by reductions in rehospitalizations and later ischemic complications...
  29. ncbi request reprint Relation of myocardial perfusion to mortality after primary percutaneous coronary intervention
    Juhana Karha
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 95:980-2. 2005
    ..This observation has important implications for the methods of evaluating primary PCI results and the strategies used to improve myocardial reperfusion...
  30. ncbi request reprint Prevalence of conventional risk factors in patients with coronary heart disease
    Umesh N Khot
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    JAMA 290:898-904. 2003
    ..This claim implies that other factors play a significant role in CHD and has led to considerable interest in nontraditional risk factors and genetic causes of CHD...
  31. ncbi request reprint Primary percutaneous coronary intervention for acute MI: improving access and outcomes
    Juhana Karha
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 72:559-60, 562, 565-6 passim. 2005
    ..Multiple clinical trials in the past 10 years have addressed ways to improve PCI as primary therapy for acute MI. Logistic strategies to improve access to PCI are being studied...
  32. ncbi request reprint Images in cardiovascular medicine. Tako-tsubo--like transient left ventricular dysfunction
    John P Girod
    Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, Ohio 44195, USA
    Circulation 107:e120-1. 2003
  33. ncbi request reprint Flow-dependent changes resulting in restoration of patency of the left internal mammary artery graft after documented atresia
    Raja Nawaz
    Department of Cardiology, New York Methodist Hospital, 476 6th Street, Brooklyn, NY 11215, USA
    J Invasive Cardiol 23:207-10. 2011
    ..We report a patient in whom the LIMA was occluded 2 years after CABG, but was found to be completely patent 5 years later, after worsening of the left anterior descending artery disease...
  34. ncbi request reprint Improved clinical outcomes with abciximab therapy in acute myocardial infarction: a systematic overview of randomized clinical trials
    David E Kandzari
    Division of Cardiology, Department of Medicine, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 147:457-62. 2004
    ....
  35. ncbi request reprint The relation between extent of coronary artery disease measured by quantitative coronary angiography and changes in lipid profile: insights from trials of atherosclerosis regression
    Sorin J Brener
    Division of Cardiology, New York Methodist Hospital, Brooklyn, NY 11215, USA
    J Invasive Cardiol 20:261-5. 2008
    ..While favorable changes in atherogenic lipids are indisputably associated with improved clinical outcomes, a similar correlation with quantitative coronary angiography (QCA) parameters is more difficult to document...
  36. ncbi request reprint Effect of uncoated stenting versus balloon angioplasty alone of long coronary (>20 mm) versus shorter narrowings on one-year event-free survival
    Fernando A Cura
    Department of Cardiology, Instituto Cardiovascular de Buenos Aires, Argentina
    Am J Cardiol 91:587-90. 2003
  37. ncbi request reprint The influence of peripheral arterial disease on outcomes: a pooled analysis of mortality in eight large randomized percutaneous coronary intervention trials
    Jacqueline Saw
    Department of Medicine, Division of Cardiology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Coll Cardiol 48:1567-72. 2006
    ..We aimed to evaluate clinical outcomes among peripheral arterial disease (PAD) patients following percutaneous coronary intervention (PCI)...
  38. ncbi request reprint Impaired myocardial perfusion score and inflammatory markers in patients undergoing primary angioplasty for acute myocardial infarction
    J Emilio Exaire
    Instituto Nacional de Cardiologia, Mexico City, Mexico
    Arch Cardiol Mex 76:376-82. 2006
    ....
  39. doi request reprint Effect of rosuvastatin therapy on coronary artery stenoses assessed by quantitative coronary angiography: a study to evaluate the effect of rosuvastatin on intravascular ultrasound-derived coronary atheroma burden
    Christie M Ballantyne
    Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, and Center for Cardiovascular Disease Prevention, Methodist DeBakey Heart and Vascular Center, Houston, Tex 77030, USA
    Circulation 117:2458-66. 2008
    ..Intravascular ultrasound showed atheroma volume regression in a single coronary artery with <50% angiographic luminal narrowing...
  40. ncbi request reprint Wish list and REALITY: choice of stents and end points for treatment of de novo coronary artery lesions
    Sorin J Brener
    JAMA 295:937-8. 2006
  41. ncbi request reprint CABG or PCI? An interventional cardiologist's perspective. To stent or to operate: is this the question?
    Sorin J Brener
    Cleve Clin J Med 73:340, 343. 2006