G H Barnett

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint The modern brain tumor operating room: from standard essentials to current state-of-the-art
    Gene H Barnett
    Brain Tumor Institute and Department of Neurosurgery, The Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Neurooncol 69:25-33. 2004
  2. ncbi request reprint Stereotactic radiosurgery--an organized neurosurgery-sanctioned definition
    Gene H Barnett
    Taussig Cancer Center, Brain Tumor Institute, Cleveland, Ohio 44195, USA
    J Neurosurg 106:1-5. 2007
  3. ncbi request reprint Recent advances in the treatment of skull base tumors using radiation
    G H Barnett
    Brain Tumor and Neuro Oncology Center, Department of Neurological Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Neurosurg Clin N Am 11:587-96. 2000
  4. ncbi request reprint The role of image-guided technology in the surgical planning and resection of gliomas
    G H Barnett
    The Neuro oncology and Brain Tumor Center, The Cleveland Clinic Foundation, OH 44195, USA
    J Neurooncol 42:247-58. 1999
  5. ncbi request reprint Frameless stereotaxy with scalp-applied fiducial markers for brain biopsy procedures: experience in 218 cases
    G H Barnett
    Center for Computer Assisted Neurosurgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Neurosurg 91:569-76. 1999
  6. ncbi request reprint Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo
    S Kondo
    Department of Neurosurgery and Brain Tumor and Neuro Oncology Center, The Cleveland Clinic Foundation, Ohio 44195, USA
    Cancer Res 58:962-7. 1998
  7. ncbi request reprint T cell adoptive immunotherapy of newly diagnosed gliomas
    G E Plautz
    Center for Surgery Research, The Cleveland Clinic Foundation, Ohio 44195, USA
    Clin Cancer Res 6:2209-18. 2000
  8. ncbi request reprint The CDK inhibitor, p27Kip1, is required for IL-4 regulation of astrocyte proliferation
    J Liu
    Department of Neurological Surgery, The Cleveland Clinic Foundation, OH 44195, USA
    J Immunol 159:812-9. 1997
  9. ncbi request reprint Successful conversion from a linear accelerator-based program to a Gamma Knife radiosurgery program: the Cleveland Clinic experience
    J H Suh
    Department of Radiation Oncology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Stereotact Funct Neurosurg 72:159-67. 1999
  10. ncbi request reprint Tumor distribution and survival in six patients with brain metastases from cervical carcinoma
    A S Mahmoud-Ahmed
    Department of Radiation Oncology, The Brain Tumor and Neuro-Oncology Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Gynecol Oncol 81:196-200. 2001

Research Grants

Detail Information

Publications79

  1. ncbi request reprint The modern brain tumor operating room: from standard essentials to current state-of-the-art
    Gene H Barnett
    Brain Tumor Institute and Department of Neurosurgery, The Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Neurooncol 69:25-33. 2004
    ..Also, we speculate on the additional capabilities of the brain tumor OR of the near future...
  2. ncbi request reprint Stereotactic radiosurgery--an organized neurosurgery-sanctioned definition
    Gene H Barnett
    Taussig Cancer Center, Brain Tumor Institute, Cleveland, Ohio 44195, USA
    J Neurosurg 106:1-5. 2007
  3. ncbi request reprint Recent advances in the treatment of skull base tumors using radiation
    G H Barnett
    Brain Tumor and Neuro Oncology Center, Department of Neurological Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    Neurosurg Clin N Am 11:587-96. 2000
    ..Only with time, however, will we be certain of their true role in the management of tumors of the skull base...
  4. ncbi request reprint The role of image-guided technology in the surgical planning and resection of gliomas
    G H Barnett
    The Neuro oncology and Brain Tumor Center, The Cleveland Clinic Foundation, OH 44195, USA
    J Neurooncol 42:247-58. 1999
    ..Intraoperative imaging such as ultrasonography or MRI may expand the utility of these systems in the foreseeable future...
  5. ncbi request reprint Frameless stereotaxy with scalp-applied fiducial markers for brain biopsy procedures: experience in 218 cases
    G H Barnett
    Center for Computer Assisted Neurosurgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Neurosurg 91:569-76. 1999
    ....
  6. ncbi request reprint Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo
    S Kondo
    Department of Neurosurgery and Brain Tumor and Neuro Oncology Center, The Cleveland Clinic Foundation, Ohio 44195, USA
    Cancer Res 58:962-7. 1998
    ..The retroviral transfer of CPP32beta or Mch2alpha, therefore, may be a novel and promising approach for the treatment of malignant glioma, an invariably fatal tumor...
  7. ncbi request reprint T cell adoptive immunotherapy of newly diagnosed gliomas
    G E Plautz
    Center for Surgery Research, The Cleveland Clinic Foundation, Ohio 44195, USA
    Clin Cancer Res 6:2209-18. 2000
    ..This Phase I clinical trial of adoptive immunotherapy for patients with newly diagnosed malignant gliomas demonstrates feasibility, lack of long-term toxicity, and several objective clinical responses...
  8. ncbi request reprint The CDK inhibitor, p27Kip1, is required for IL-4 regulation of astrocyte proliferation
    J Liu
    Department of Neurological Surgery, The Cleveland Clinic Foundation, OH 44195, USA
    J Immunol 159:812-9. 1997
    ..Antisense p27 also abrogated IL-4-mediated elevation of p27 in whole cell lysates and cyclin E/cdk2 complexes. These findings demonstrate that IL-4 regulates the cell cycle machinery of astroglial cells via a p27Kip1 braking mechanism...
  9. ncbi request reprint Successful conversion from a linear accelerator-based program to a Gamma Knife radiosurgery program: the Cleveland Clinic experience
    J H Suh
    Department of Radiation Oncology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Stereotact Funct Neurosurg 72:159-67. 1999
    ..With proper planning, education, and awareness, the opening of a Gamma Knife Center can greatly increase the volume of radiosurgery performed when compared with a LINAC-based program...
  10. ncbi request reprint Tumor distribution and survival in six patients with brain metastases from cervical carcinoma
    A S Mahmoud-Ahmed
    Department of Radiation Oncology, The Brain Tumor and Neuro-Oncology Center, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Gynecol Oncol 81:196-200. 2001
    ....
  11. ncbi request reprint Metastatic seeding of the stereotactic biopsy tract in glioblastoma multiforme: case report and review of the literature
    M P Steinmetz
    Department of Neurosurgery, Brain Tumor and Neuro-Oncology Center, The Cleveland Clinic, OH 44195, USA
    J Neurooncol 55:167-71. 2001
    ..Further research will allow one to determine the radiosensitivity of these tumors and determine which patients may benefit from a radiosurgical or fractionated radiotherapy boost to the biopsy tract...
  12. ncbi request reprint Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation
    S Kondo
    Department of Neurosurgery, Brain Tumor Neuro Oncology Center, The Cleveland Clinic Foundation, Ohio 44195, USA
    FASEB J 12:801-11. 1998
    ..Regulation of these two distinct pathways may be dependent on the expression of ICE or CDKIs...
  13. ncbi request reprint Delayed appearance of carbon granulomas of the scalp after use of carbon fiber pins for refixation of a stereotactic head frame. Case report
    W E McCormick
    Department of Neurosurgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Neurosurg 95:129-31. 2001
    ..The lesions in this case arose a few months after initiation of chemotherapy for the patient's brain tumor. The relationship of carbon and cutaneous granuloma formation to adjuvant therapies and treatment strategies is discussed...
  14. pmc Genetic vulnerability following traumatic brain injury: the role of apolipoprotein E
    N Nathoo
    Department of Neurosurgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, 44195 Ohio, USA
    Mol Pathol 56:132-6. 2003
    ..Evidence from experimental and clinical brain injury studies confirms that APOE plays an important role in the response of the brain to injury...
  15. ncbi request reprint The effect of radiation therapy on brain metastases from endometrial carcinoma: a retrospective study
    A S Mahmoud-Ahmed
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Gynecol Oncol 83:305-9. 2001
    ..Although the number of patients was small, radiation therapy alone resulted in poor survival. Combination treatment with surgery and radiation therapy may improve survival for selected patients...
  16. ncbi request reprint Clinical and economic consequences of early discharge of patients following supratentorial stereotactic brain biopsy
    W Kaakaji
    Department of Neurological Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA
    J Neurosurg 94:892-8. 2001
    ..Extended outpatient observation (8-23 hours) is not clinically necessary and may be economically prohibitive in the setting of a teaching hospital...
  17. pmc Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography
    O B Chernova
    Department of Neurosurgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Br J Cancer 88:1889-93. 2003
    ..Our data suggest that HPLC is a reliable and sensitive method for detection of allelic losses in tumour samples and it is a favourable alternative for high-sensitivity LOH detection in both research and diagnostic environments...
  18. ncbi request reprint Results of linear accelerator-based stereotactic radiosurgery for recurrent and newly diagnosed acoustic neuromas
    J H Suh
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Int J Cancer 90:145-51. 2000
    ..Since there was a high risk of cranial nerve neuropathy, we do not recommend using only computed tomography-based planning and high prescription doses. Int. J. Cancer (Radiat. Oncol. Invest.) 90, 145-151 (2000)...
  19. pmc Pathobiology of brain metastases
    N Nathoo
    Brain Tumor Institute, Taussig Cancer Center and Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44122, USA
    J Clin Pathol 58:237-42. 2005
    ..Advances in this understanding of the pathobiology of brain metastasis may lead to novel targeted treatment paradigms and a better prognosis for patients with brain metastatic disease...
  20. pmc mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line
    S Kondo
    Department of Neurosurgery S80, Cleveland Clinic Foundation, OH 44195, USA
    Br J Cancer 74:1263-8. 1996
    ..These findings suggest that the mdm2 gene may play an important role in the development of MDR phenotype in human tumours...
  21. pmc The eicosanoid cascade: possible role in gliomas and meningiomas
    N Nathoo
    Brain Tumour Institute and Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, 44195 Ohio, USA
    J Clin Pathol 57:6-13. 2004
    ....
  22. ncbi request reprint Measurement of tissue electrical impedance confirms stereotactically localized internal segment of the globus pallidus during surgery
    V Siemionow
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Neurosci Methods 96:113-7. 2000
    ..The accuracy of the impedance measurement is acceptable, and the procedure can be recommended as an aid to confirm the stereotactically localized Gpi during neurological surgery...
  23. ncbi request reprint Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway
    B P Barna
    Rammelkamp Center for Education and Research, MetroHealth Medical Center, Cleveland, Ohio 44109, USA
    Cell Immunol 208:18-24. 2001
    ..Data suggest that astrocyte IL-4R alpha expression is upregulated by EGF but not by IL-4 in an EGF-receptor-dependent manner and that mechanisms are independent of MAPK activation...
  24. ncbi request reprint Identification and characterization of human beta 2-chimaerin: association with malignant transformation in astrocytoma
    S Yuan
    Brain Tumor Center of the Department of Neurological Surgery, Cleveland Clinic Foundation, Ohio 44195, USA
    Cancer Res 55:3456-61. 1995
    ..The down-regulation of beta 2-chimaerin expression in the high-grade gliomas suggests that decreased expression of this gene may be a feature of progression in the development of malignant glioma...
  25. ncbi request reprint Metastases to the brain: current management perspectives
    Narendra Nathoo
    Brain Tumor Institute, Department of Neurosurgery, Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Expert Rev Neurother 4:633-40. 2004
    ..Efforts are ongoing to understand the molecular biology of brain metastases...
  26. doi request reprint Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy
    Samuel T Chao
    Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Cancer 113:2198-204. 2008
    ....
  27. ncbi request reprint RPA classification has prognostic significance for surgically resected single brain metastasis
    Rahul D Tendulkar
    Department of Radiation Oncology, Brain Tumor Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 66:810-7. 2006
    ..To retrospectively evaluate prognostic factors that correlate with overall survival among patients with a surgically resected single brain metastasis...
  28. ncbi request reprint Five-year survivors of brain metastases: a single-institution report of 32 patients
    Samuel T Chao
    Department of Radiation Oncology, Brain Tumor Institute, Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 66:801-9. 2006
    ..To report on 32 patients who survived > or = 5 years from brain metastases treated at a single institution...
  29. ncbi request reprint Local control of brain metastases by stereotactic radiosurgery in relation to dose to the tumor margin
    Michael A Vogelbaum
    Brain Tumor Institute and Departments of Biostatistics, Neurosurgery, and Radiation Oncology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Neurosurg 104:907-12. 2006
    ..The goal in this retrospective study was to determine whether differences in doses to the margins of brain metastases affect the ability of SRS to achieve local control...
  30. ncbi request reprint The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
    Igor Garkavtsev
    Edwin L Steele Laboratory for Tumour Biology, Department of Radiation Oncology Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 428:328-32. 2004
    ..These results indicate that ING4 has an important role in brain tumour pathogenesis...
  31. ncbi request reprint Posterior fossa metastases: risk of leptomeningeal disease when treated with stereotactic radiosurgery compared to surgery
    Vitaly E Siomin
    Department of Neurosurgery, Brain Tumor Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurooncol 67:115-21. 2004
    ..Our objective was to compare the incidence of LMD in patients with posterior fossa metastases (PFM) following stereotactic radiosurgery (SRS) versus surgical resection...
  32. ncbi request reprint Increased expression of 5-lipoxygenase in high-grade astrocytomas
    Narendra Nathoo
    Brain Tumor Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Neurosurgery 58:347-54; discussion 347-54. 2006
    ..In this study, we investigated whether 5-LO is expressed in human astrocytomas and what effect its expression may have on patient outcome...
  33. ncbi request reprint Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization
    Michael R Rossi
    Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York, USA
    Genes Chromosomes Cancer 44:85-96. 2005
    ..These regions of the genome define small numbers of candidate genes that are within the deletions. The aCGH analysis also defined the spectrum of gain and loss of genomic regions in low-grade oligodendrogliomas...
  34. ncbi request reprint Update of stereotactic radiosurgery for brain tumors
    John H Suh
    Department of Radiation Oncology, Brain Tumor Institute, Cleveland Clinic Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Curr Opin Neurol 17:681-6. 2004
    ..This paper will review the recent publications of stereotactic radiosurgery for brain tumors...
  35. ncbi request reprint Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme
    Aimee L Quan
    Department of Radiation Oncology, Brain Tumor Institute, The Cleveland Clinic Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 63:695-703. 2005
    ..The purpose of this study is to determine the prognostic significance of EGFR amplification in patients with GBM treated at the Cleveland Clinic Foundation...
  36. ncbi request reprint Pre-irradiation 9-amino [20s] camptothecin (9-AC) in patients with newly diagnosed glioblastoma multiforme
    Daniel Farray
    Loyola University Medical Center, Maywood, Illinois, USA
    Invest New Drugs 24:177-80. 2006
    ..To evaluate the efficacy of 9-amino [20s] camptothecin (9-AC) given before radiation therapy to patients with newly diagnosed glioblastoma multiforme (GBM)...
  37. ncbi request reprint The Brain Tumor Cooperative Group NIH Trial 87-01: a randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiation therapy, and carmustine
    Robert G Selker
    Neurosurgery 51:343-55; discussion 355-7. 2002
    ..The objective of the Brain Tumor Cooperative Group NIH Trial 87-01 trial was to investigate the effect of additional implanted radiation therapy in newly diagnosed patients with pathologically confirmed malignant gliomas...
  38. doi request reprint Multidisciplinary management of colorectal brain metastases: a retrospective study
    Tim J Kruser
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Cancer 113:158-65. 2008
    ..The incidence of brain metastases (BM) from colorectal cancer (CRC) is increasing, and the management of this previously rare complication at a single institution is reported...
  39. ncbi request reprint Stage III non-small cell lung cancer and metachronous brain metastases
    Nader Moazami
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 124:113-22. 2002
    ....
  40. ncbi request reprint Results of whole brain radiotherapy in patients with brain metastases from breast cancer: a retrospective study
    Ashraf S Mahmoud-Ahmed
    Department of Radiation Oncology, Brain Tumor Institute, Cleveland Clinic Cancer Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 54:810-7. 2002
    ..To analyze the factors that affect survival in patients with brain metastases (BM) from breast cancer who were treated with whole brain radiotherapy (WBRT)...
  41. ncbi request reprint Gliomatosis cerebri: treatment results with radiotherapy alone
    Mohamed A Elshaikh
    Department of Radiation Oncology, Brain Tumor Institute, Cleveland Clinic Foundation, Ohio 44195, USA
    Cancer 95:2027-31. 2002
    ..The optimal therapeutic strategy is not well established. The impact of radiotherapy on survival in patients with GC remains undefined...
  42. doi request reprint Stereotactic radiosurgical treatment of parenchymal brain metastases from prostate adenocarcinoma
    Se Hyuk Kim
    The Brain Tumor and Neuro Oncology Center, Cleveland Clinic, Cleveland, OH 44195, USA
    Surg Neurol 69:641-6; discussion 646. 2008
    ..Prostate cancer metastatic to the brain is uncommon and has been associated historically with a poor prognosis. It has been suggested that SRS may be an effective treatment...
  43. ncbi request reprint Intensity-modulated radiation therapy (IMRT) for newly diagnosed and recurrent intracranial meningiomas: preliminary results
    Ratna Sajja
    Department of Radiation Oncology, Brain Tumor Institute, Cleveland Clinic Foundation, OH 44195, USA
    Technol Cancer Res Treat 4:675-82. 2005
    ..A greater number of patients with longer follow-up after treatment may be needed to determine treatment variables predicting for long-term tumor control...
  44. ncbi request reprint Survival by radiation therapy oncology group recursive partitioning analysis class and treatment modality in patients with brain metastases from malignant melanoma: a retrospective study
    Jeffrey C Buchsbaum
    Department of Radiation Oncology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cancer 94:2265-72. 2002
    ....
  45. ncbi request reprint Influence of apoptosis on neurological outcome following traumatic cerebral contusion
    Narendra Nathoo
    Department of Neurosurgery and Wentworth Hospital, Nelson R Mandela School of Medicine, Durban, South Africa
    J Neurosurg 101:233-40. 2004
    ..The present study was undertaken to confirm the presence of apoptosis in the periischemic zone (PIZ) of traumatic cerebral contusions and to determine the role of apoptosis, if any, in neurological outcome...
  46. ncbi request reprint Epidermal growth factor receptor is not amplified in schwannomas
    Richard A Prayson
    Department of Anatomic Pathology L25, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Ann Diagn Pathol 11:326-9. 2007
    ....
  47. ncbi request reprint Propylthiouracil-induced chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent high grade glioma: a phase I/II study
    Aleck A Hercbergs
    Department of Radiation Oncology, Cleveland Clinic Foundation, 9500 Euclid Ave, S80, Cleveland, OH 44195, USA
    Anticancer Res 23:617-26. 2003
    ..Thyroid function was suppressed to reduce IGF-1 levels in glioma patients and high-dose tamoxifen administered...
  48. ncbi request reprint Stereotactic radiosurgery for brain tumors in pediatric patients
    John H Suh
    Brain Tumor Institute, Department of Radiation Oncology, T 28, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Technol Cancer Res Treat 2:141-6. 2003
    ..This article will review the results and logistical issues of this modality in the management of pediatric brain tumors...
  49. ncbi request reprint Recurrent head-and-neck chemodectomas: a comparison of surgical and radiotherapeutic results
    Mohamed A Elshaikh
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 52:953-6. 2002
    ..To compare the outcome of salvage radiotherapy (RT) and surgery for recurrent head-and-neck chemodectomas...
  50. doi request reprint Stereotactic radiosurgical treatment of brain metastases in older patients
    Se Hyuk Kim
    The Brain Tumor and Neuro Oncology Center, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cancer 113:834-40. 2008
    ..This study was designed to evaluate the therapeutic effect of stereotactic radiosurgery (SRS) in patients aged > or =75 years who presented with brain metastasis...
  51. ncbi request reprint Use of the Radiation Therapy Oncology Group recursive partitioning analysis classification system and predictors of survival in 19 women with brain metastases from ovarian carcinoma
    Philip G Chen
    Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cancer 104:2174-80. 2005
    ....
  52. ncbi request reprint Long-term results of radiosurgery for refractory cluster headache
    Shearwood McClelland
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Neurosurgery 59:1258-62; discussion 1262-3. 2006
    ..To address this issue, we present our findings from the largest retrospective series of patients undergoing radiosurgery for CH with extended follow-up periods...
  53. ncbi request reprint Perioperative complications of blood brain barrier disruption under general anesthesia: a retrospective review
    Nabil M Elkassabany
    Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA
    J Neurosurg Anesthesiol 20:45-8. 2008
    ....
  54. doi request reprint Review of the treatment of trigeminal neuralgia with gamma knife radiosurgery
    Susan Guo
    College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Stereotact Funct Neurosurg 86:135-46. 2008
    ..Gamma knife radiosurgery has been increasingly used in the treatment of trigeminal neuralgia as a non-invasive alternative to microvascular decompression and rhizotomies...
  55. ncbi request reprint The impact of genotype on outcome in oligodendroglioma: validation of the loss of chromosome arm 1p as an important factor in clinical decision making
    Andrew A Kanner
    The Brain Tumor Institute, The Cleveland Clinic Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurosurg 104:542-50. 2006
    ..Anaplastic oligodendrogliomas with allelic loss of 1p have been associated with chemosensitivity and a longer patient survival period...
  56. ncbi request reprint The role of 111indium-octreotide brain scintigraphy in the diagnosis of cranial, dural-based meningiomas
    Narendra Nathoo
    Department of Neurosurgery, The Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Neurooncol 81:167-74. 2007
    ..We report the use of (111)indium-octreotide brain scintigraphy (OBS) for the non-invasive differentiation of meningiomas from other cranial dural-based pathology...
  57. ncbi request reprint Translational research in gliomas: Quo Vadis?
    Gene H Barnett
    Department of Neurosurgery, Brain Tumor Institute, The Cleveland Clinic Tausig Cancer Center, Ohio, USA
    Clin Neurosurg 53:154-6. 2006
    ..Although described by some as the "molecular era" of human brain tumor management, it is probably more accurate to describe it as the era of "translational research."..
  58. ncbi request reprint Repeat trigeminal nerve radiosurgery for refractory cluster headache fails to provide long-term pain relief
    Shearwood McClelland
    Headache 47:298-300. 2007
    ..However, there have been no reports of repeated radiosurgery in this patient population. We present our findings from the first reports of repeat radiosurgery for MRCH...
  59. ncbi request reprint Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue arising in the lateral ventricle
    Todd W Kelley
    Division of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    Leuk Lymphoma 46:1423-7. 2005
    ..This rare case provides insight into the pathophysiology of MALT lymphomas...
  60. ncbi request reprint George W. Crile, Ohio's first neurosurgeon, and his relationship with Harvey Cushing
    Narendra Nathoo
    Brain Tumor Institute, The Taussig Cancer Center, Cleveland, Ohio, USA
    J Neurosurg 103:378-86. 2005
    ....
  61. ncbi request reprint Serum S100beta: a noninvasive marker of blood-brain barrier function and brain lesions
    Andrew A Kanner
    Brain Tumor Institute, The Cleveland Clinic, Ohio 44195, USA
    Cancer 97:2806-13. 2003
    ....
  62. ncbi request reprint Increased expression of 5-lipoxygenase in glioblastoma multiforme
    Mladen Golubic
    Brain Tumor Institute, Cleveland Clinic Foundation, OH 44195, USA
    Adv Exp Med Biol 525:205-8. 2003
  63. ncbi request reprint Brachytherapy for intracranial meningioma using a permanently implanted iodine-125 seed
    Patrick C Obasi
    Howard University College of Medicine, Washington, DC, USA
    Stereotact Funct Neurosurg 79:33-43. 2002
    ..To investigate the response and complications of iodine-125 brachytherapy for the treatment of recurrent and newly diagnosed meningiomas. Clinical cases of 2 patients treated with this method are presented...
  64. ncbi request reprint Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
    Shaik Ohidar Rahaman
    Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, OH 44195, USA
    Oncogene 21:8404-13. 2002
    ..Therefore, targeting Stat3 signaling may provide a potential therapeutic intervention for GBM...
  65. ncbi request reprint Intracranial navigation by using low-field intraoperative magnetic resonance imaging: preliminary experience
    Andrew A Kanner
    Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Mmedicine, Tel Aviv University, Israel
    J Neurosurg 97:1115-24. 2002
    ..The authors report their initial experience with a novel neuronavigation system coupled to a low-field iMR imaging system...
  66. ncbi request reprint Chromosome 1p allelic loss by fluorescence in situ hybridization is not observed in dysembryoplastic neuroepithelial tumors
    Richard A Prayson
    Department of Neurological Surgery, Cleveland Clinic Foundation, OH 44195, USA
    Am J Clin Pathol 118:512-7. 2002
    ..LOH on chromosome 1p may be a useful differential diagnostic feature (favoring oligodendroglioma) in a subset of cases in which specimen fragmentation or size raises the differential diagnosis of DNT vs oligodendroglioma...
  67. ncbi request reprint Brain-invasive solitary fibrous tumor of the meninges: report of a case
    Elias A Castilla
    Department of Anatomic Pathology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Int J Surg Pathol 10:217-21. 2002
    ..Focal infiltration into the underlying brain parenchyma was observed. The tumor was CD34 positive and EMA negative...
  68. ncbi request reprint Cyclooxygenase-2 (COX-2) expression by immunohistochemistry in glioblastoma multiforme
    Richard A Prayson
    Brain Tumor Center and the Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Ann Diagn Pathol 6:148-53. 2002
    ..These findings are significant in that therapeutic agents, which inhibit COX-2, are currently available and may play a role in the management of glioblastoma multiforme...
  69. ncbi request reprint Factors associated with improved survival in patients with brain metastases from esophageal cancer: a retrospective review
    Deepak Khuntia
    Brain Tumor Institute, Department of Radiation Oncology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Technol Cancer Res Treat 2:267-72. 2003
    ..We recommend esophageal cancer patients with BrM be enrolled in clinical trials to better delineate the role of treatment and potentially improve results...
  70. ncbi request reprint Cyclooxygenase-2 in oligodendroglial neoplasms
    Elias A Castilla
    Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cancer 98:1465-72. 2003
    ..Although increased expression of cyclooxygenase-2 (COX-2) has been described in association with a variety of neoplasms, including tumors of astrocytic derivation, limited data are available on COX-2 expression in oligodendrogliomas...
  71. ncbi request reprint Trigeminal nerve schwannoma with ancient change. Case report and review of the literature
    Kene Ugokwe
    Brain Tumor Institute, Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurosurg 102:1163-5. 2005
    ..To the authors' knowledge, this is the first independent report of this histological variant in an intracranial schwannoma...
  72. ncbi request reprint In touch with robotics: neurosurgery for the future
    Narendra Nathoo
    Brain Tumor Institute and Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Neurosurgery 56:421-33; discussion 421-33. 2005
    ..This article reviews the role of robotic technology in the context of neurosurgery...
  73. ncbi request reprint Prevention of thromboembolism after neurosurgery for brain and spinal tumors
    Teresa L Carman
    Department of Cardiovascular Medicine, Section of Vascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    South Med J 96:17-22. 2003
    ..Deep venous thrombosis (DVT) is a major cause of morbidity and mortality after surgery for primary and metastatic brain tumors...
  74. ncbi request reprint W. James Gardner: pioneer neurosurgeon and inventor
    Narendra Nathoo
    Brain Tumor Institute and Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurosurg 100:965-73. 2004
    ..During his career, he authored 256 publications and one book on the dysraphic states. Many of his contributions to the discipline of neurosurgery are now taken for granted...
  75. ncbi request reprint Gamma knife radiosurgery for trigeminal neuralgia: comparing the use of a 4-mm versus concentric 4- and 8-mm collimators
    Andrew A Kanner
    Department of Neurosurgery, The Cleveland Clinic Health System Gamma Knife Center, Cleveland, Ohio, USA
    Stereotact Funct Neurosurg 82:49-57. 2004
    ..Combined use of 4- and 8-mm collimators results in a larger target volume, which would potentially treat a larger region of the nerve without increasing the maximum dose...
  76. ncbi request reprint Characterization of the 1p/19q chromosomal loss in oligodendrogliomas using comparative genomic hybridization arrays (CGHa)
    John K Cowell
    Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    J Neuropathol Exp Neurol 63:151-8. 2004
    ....
  77. ncbi request reprint Posterior fossa metastases: aggressive treatment improves survival
    Andrew A Kanner
    Department of Neurosurgery, Brain Tumor Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Stereotact Funct Neurosurg 81:18-23. 2003
    ..Brain metastases are a leading cause of mortality and morbidity in patients with malignancies. Infratentorial location has been considered a negative prognostic factor...
  78. ncbi request reprint Results of whole brain radiotherapy and recursive partitioning analysis in patients with brain metastases from renal cell carcinoma: a retrospective study
    Steven B Cannady
    Department of Otolaryngology, Brain Tumor Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int J Radiat Oncol Biol Phys 58:253-8. 2004
    ..To determine the benefit of whole brain radiotherapy (WBRT) and the use of the Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis (RPA) classification system in patients with brain metastases from renal cell carcinoma...
  79. ncbi request reprint Brain metastases from bladder carcinoma: presentation, treatment and survival
    Ashraf S Mahmoud-Ahmed
    Department of Radiation Oncology, Brain Tumor Institute, Taussig Cancer Center, 9500 Euclid Avenue, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    J Urol 167:2419-22. 2002
    ..We report the presentation of brain metastases from bladder carcinoma. We investigated the role of whole brain radiation therapy for treating this disease...

Research Grants2

  1. Therapeutic Studies of Primary CNS Malignancies-NABTT
    Gene Barnett; Fiscal Year: 2007
    ..abstract_text> ..