William Baldwin

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. pmc Platelets: versatile modifiers of innate and adaptive immune responses to transplants
    William M Baldwin
    Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Curr Opin Organ Transplant 16:41-6. 2011
  2. pmc B cells in cardiac transplants: from clinical questions to experimental models
    William M Baldwin
    Department of Immunology and the Glickman Urological and Kidney Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    Semin Immunol 24:122-30. 2012
  3. pmc Antibody-mediated rejection: emergence of animal models to answer clinical questions
    William M Baldwin
    Department of Immunology and the Glickman Urological and Kidney Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    Am J Transplant 10:1135-42. 2010
  4. pmc Antibody-mediated rejection in human cardiac allografts: evaluation of immunoglobulins and complement activation products C4d and C3d as markers
    E R Rodriguez
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Transplant 5:2778-85. 2005
  5. doi request reprint B cells and plasma cells in coronaries of chronically rejected cardiac transplants
    Jennifer R Wehner
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Transplantation 89:1141-8. 2010
  6. doi request reprint Hapten application to the skin induces an inflammatory program directing hapten-primed effector CD8 T cell interaction with hapten-presenting endothelial cells
    Danielle D Kish
    Department of Immunology, Cleveland Clinic, Cleveland, OH 44195, USA
    J Immunol 186:2117-26. 2011
  7. ncbi request reprint Update on cardiac transplantation pathology
    Carmela D Tan
    Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 131:1169-91. 2007
  8. pmc High renal ischemia temperature increases neutrophil chemoattractant production and tissue injury during reperfusion without an identifiable role for CD4 T cells in the injury
    Nobuyuki Fukuzawa
    Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Transpl Immunol 22:62-71. 2009

Research Grants

  1. COMPLEMENT MEDIATED INJURY IN ALLOGRAFT REJECTION
    William Baldwin; Fiscal Year: 2001
  2. COMPLEMENT MEDIATED INJURY IN ALLOGRAFT REJECTION
    William Baldwin; Fiscal Year: 2007

Collaborators

Detail Information

Publications8

  1. pmc Platelets: versatile modifiers of innate and adaptive immune responses to transplants
    William M Baldwin
    Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Curr Opin Organ Transplant 16:41-6. 2011
    ..This review focuses on recent findings that link platelets to inflammatory responses of relevance to transplants...
  2. pmc B cells in cardiac transplants: from clinical questions to experimental models
    William M Baldwin
    Department of Immunology and the Glickman Urological and Kidney Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    Semin Immunol 24:122-30. 2012
    ..Similarly, the role of proinflammatory adipokines in the formation or function of epicardial lymphoid nodules has not been studied. These clinical observations provide critical questions to be addressed in experimental models...
  3. pmc Antibody-mediated rejection: emergence of animal models to answer clinical questions
    William M Baldwin
    Department of Immunology and the Glickman Urological and Kidney Disease Institute, The Cleveland Clinic, Cleveland, OH, USA
    Am J Transplant 10:1135-42. 2010
    ..As small animal models become better defined, it is anticipated that they will be more widely used to answer further questions concerning mechanisms of antibody-mediated tissue injury as well as to design therapeutic interventions...
  4. pmc Antibody-mediated rejection in human cardiac allografts: evaluation of immunoglobulins and complement activation products C4d and C3d as markers
    E R Rodriguez
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Transplant 5:2778-85. 2005
    ..Concomitant use of C4d and C3d is very useful to diagnose AMR, when correlated with clinical parameters of graft function. AMR in heart transplant patients can occur many months or years after transplant...
  5. doi request reprint B cells and plasma cells in coronaries of chronically rejected cardiac transplants
    Jennifer R Wehner
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Transplantation 89:1141-8. 2010
    ..The presence of C4d on FDCs in tertiary lymphoid nodules suggests active antigen presentation...
  6. doi request reprint Hapten application to the skin induces an inflammatory program directing hapten-primed effector CD8 T cell interaction with hapten-presenting endothelial cells
    Danielle D Kish
    Department of Immunology, Cleveland Clinic, Cleveland, OH 44195, USA
    J Immunol 186:2117-26. 2011
    ....
  7. ncbi request reprint Update on cardiac transplantation pathology
    Carmela D Tan
    Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 131:1169-91. 2007
    ..The grading system for evaluation of heart transplant biopsies published in 1990 was revised in 2004 after more than a decade of implementation...
  8. pmc High renal ischemia temperature increases neutrophil chemoattractant production and tissue injury during reperfusion without an identifiable role for CD4 T cells in the injury
    Nobuyuki Fukuzawa
    Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Transpl Immunol 22:62-71. 2009
    ....

Research Grants11

  1. COMPLEMENT MEDIATED INJURY IN ALLOGRAFT REJECTION
    William Baldwin; Fiscal Year: 2001
    ..If these agents also prove effective in delaying acute rejection, then they could have clinical application in rejection episodes that are associated with complement activation. ..
  2. COMPLEMENT MEDIATED INJURY IN ALLOGRAFT REJECTION
    William Baldwin; Fiscal Year: 2007
    ..Most importantly, we will use our extensive clinical material to verify the relevance of our experimental findings to humans. ..