Affiliation: Cleveland Clinic Foundation
- It is not about the bike, it is about the pedaling: forced exercise and Parkinson's diseaseJay L Alberts
Department of Biomedical Engineering, Center for Neurological Restoration, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
Exerc Sport Sci Rev 39:177-86. 2011..A novel forced exercise intervention is described that has resulted in improved motor function and central nervous system function in PD patients...
- Bilateral subthalamic stimulation impairs cognitive-motor performance in Parkinson's disease patientsJay L Alberts
Department of Biomedical Engineering, Center for Neurological Restoration, Cleveland Clinic, Cleveland, OH 44195, USA
Brain 131:3348-60. 2008..From a clinical perspective, these results underscore the need to assess cognitive and motor function simultaneously during DBS programming as these conditions may better reflect the context in which daily activities are performed...
- Are two leads always better than one: an emerging case for unilateral subthalamic deep brain stimulation in Parkinson's diseaseJay L Alberts
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Exp Neurol 214:1-5. 2008....
- The persistent effects of unilateral pallidal and subthalamic deep brain stimulation on force control in advanced Parkinson's patientsJ L Alberts
Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA
Parkinsonism Relat Disord 14:481-8. 2008..Unilateral DBS implantation of either site should be considered an option for those patients in which bilateral procedures are contraindicated...
- Reversing cognitive-motor impairments in Parkinson's disease patients using a computational modelling approach to deep brain stimulation programmingAnneke M M Frankemolle
Department of Biomedical Engineering ND20, Center for Neurological Restoration, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Brain 133:746-61. 2010....
- Customizing deep brain stimulation to the patient using computational modelsCameron C McIntyre
Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4228-9. 2009....
- Effects of combined robotic therapy and repetitive-task practice on upper-extremity function in a patient with chronic strokeLibby Rosenstein
Department of Occupational Therapy, Cleveland Clinic, Cleveland, OH 44195, USA
Am J Occup Ther 62:28-35. 2008..This article describes the effect of a robotic device combined with repetitive-task practice (RTP) on upper-extremity function in a patient with chronic stroke...
- Forced, not voluntary, exercise improves motor function in Parkinson's disease patientsAngela L Ridgel
Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA
Neurorehabil Neural Repair 23:600-8. 2009..Global improvements in motor function following voluntary exercise (VE) are not widely reported in human Parkinson's disease (PD) patients...
- Objective quantification of arm rigidity in MPTP-treated primatesThomas O Mera
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
J Neurosci Methods 177:20-9. 2009..The most sensitive measures were total area, extension slope, and flexion slope. The ART system provides precise and reliable measures of rigidity that are objective and quantitative...
- Combined use of repetitive task practice and an assistive robotic device in a patient with subacute strokeEllen M Frick
Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma Health Sciences Center, Oklahoma City, Okla, USA
Phys Ther 86:1378-86. 2006..Furthermore, the case suggests that improvements in strength are not necessary for improved dexterous function, provided that a minimal level of strength is present...
- Alterations in transport path differentially affect temporal and spatial movement parametersJay L Alberts
School of Applied Physiology, Motor Control Laboratory, Georgia Institute of Technology, Atlanta, GA 30332 0356, USA
Exp Brain Res 143:417-25. 2002..These results suggest that the central nervous system may be using a spatial controller to coordinate prehensile components...
- Comparison of pallidal and subthalamic stimulation on force control in patient's with Parkinson's diseaseJay L Alberts
School of Applied Physiology, Georgia Institute of Technology, Atlanta, GA 30332, USA
Motor Control 8:484-99. 2004..DBS of the GPi and STN leads to an improvement in the motor functioning of advanced PD patients. Improvement in force-timing specification during DBS might allow PD patients to employ a feedforward method of force control...
- Contemporary linkages between EMG, kinetics and stroke rehabilitationSteven L Wolf
Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30332, USA
J Electromyogr Kinesiol 15:229-39. 2005..Clinicians and researchers interested in expanding their use of these measurement tools are encouraged to learn more about application possibilities...
- Age-related changes in grasping force modulationClaudia Voelcker-Rehage
Jacobs centre for Lifelong Learning and Institutional Development, International University Bremen, Bremen, Germany
Exp Brain Res 166:61-70. 2005..These data suggest that older adults are impaired in the accurate release of grip force. Varied force release patterns that disrupt the precision of force modulation may contribute to older adults' diminished dexterous abilities...
- Age-related differences in working memory and force control under dual-task conditionsClaudia Voelcker-Rehage
Jacobs Center for Lifelong Learning and Institutional Development, International University Bremen, Germany
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:366-84. 2006..These results suggest that cognitive motor deficits are responsible for older adults' performance decrements under dual-task conditions...
- The effects of constraint-induced therapy on precision grip: a preliminary studyJay L Alberts
School of Applied Physiology, Georgia Institute of Technology, Atlanta 30332 0356, USA
Neurorehabil Neural Repair 18:250-8. 2004..This preliminary study examines the effects of a 2-week constraint-induced therapy (CIT) intervention on the force-producing capabilities of the hemiparetic hand during the performance of a functional dexterous manipulation task...
- Effect of motor practice on dual-task performance in older adultsClaudia Voelcker Rehage
Jacobs Center for Lifelong Learning and Institutional Development, Jacobs University Bremen, Germany
J Gerontol B Psychol Sci Soc Sci 62:P141-8. 2007..After practice, older adults improved cognitive performance in dual-task conditions. Advances in age appear to be associated with a decrease in the ability to manage and coordinate multiple tasks, which remains after extended practice...
- Changes in multi-joint performance with ageRachael D Seidler
Department of Movement Science, University of Michigan, Ann Arbor, MI 48109-2214, USA
Motor Control 6:19-31. 2002..Thus, to achieve motor performance, elderly persons appear to use coactivation in a manner that is fundamentally different than young adults...
- Deep Brain Stimulation and Force Control in Parkinson'sJAY ALBERTS; Fiscal Year: 2003..The results of these studies may improve the treatment of advanced PD. ..
- Air Muscle and Task Practice in Upper Limb Stroke RehabJAY ALBERTS; Fiscal Year: 2005..This project has the potential to increase the availability of effective rehabilitation techniques to patients with stroke. ..
- Comparison of Unilateral and Bilateral Subthalamic Stimulation in Parkinson'sJay L Alberts; Fiscal Year: 2010..The combined use of this dual-task paradigm and visualization software has the potential to allow clinicians to better achieve the fundamental goal of DBS: provide maximal motor response while minimizing cognitive-motor losses. ..