Research Topics
| Huabei JiangSummaryAffiliation: Clemson University Country: USA Publications
| Collaborators
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Detail Information
Publications
Multispectral breast imaging using a ten-wavelength, 64 x 64 source/detector channels silicon photodiode-based diffuse optical tomography systemChangqing Li
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611-6131, USA
Med Phys 33:627-36. 2006..From the in vivo clinic experiment, functional images including deoxyhemoglobin, oxyhemoglobin, and water concentration are recovered and tumors are detected with correct size and position compared with the mammography...
Three-dimensional optical tomographic imaging of breast in a human subjectH Jiang
Department of Physics and Astronomy, Clemson University, SC 29634 0978, USA
IEEE Trans Med Imaging 20:1334-40. 2001..Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors...
Phase-contrast imaging of tissue using near-infrared diffusing lightHuabei Jiang
Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634 0978, USA
Med Phys 30:1048-51. 2003..The imaging method is validated using several tissue-like phantom experiments. Initial in vivo imaging of breast tissue is also presented, demonstrating the ability of this new imaging method for tumor detection...
In vivo breast imaging with diffuse optical tomography based on higher-order diffusion equationsYong Xu
Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, USA
Appl Opt 42:3163-9. 2003..Pilot clinical results from female volunteers indicate that enhanced diffuse optical tomography can quantitatively image findings such as breast cysts or implants in which the absorption and scattering coefficients are usually low...
Automated breast cancer classification using near-infrared optical tomographic imagesJames Z Wang
Clemson University, School of Computing, Clemson, South Carolina 29634, USA
J Biomed Opt 13:044001. 2008..Furthermore, the automated classification procedure provides significantly improved specificity and overall accuracy for breast cancer detection compared to those by an experienced technician through visual examination...
Measurement of particle-size distribution and concentration in heterogeneous turbid media with multispectral diffuse optical tomographyChangqing Li
Department of Physics and Astronomy, Clemson University, 118 Kinard Lab, Clemson, South Carolina 29634, USA
Appl Opt 44:1838-44. 2005....
Differentiation of cysts from solid tumors in the breast with diffuse optical tomographyXuejun Gu
Department of Physics and Astronomy, Clemson University, Clemson, SC 29634-0978, USA
Acad Radiol 11:53-60. 2004....
Absorption and scattering images of heterogeneous scattering media can be simultaneously reconstructed by use of dc dataYong Xu
Department of Physics and Astronomy, Clemson University, South Carolina 29634, USA
Appl Opt 41:5427-37. 2002..Finally, we discuss our results in light of recent theoretical findings on nonuniqueness for dc image reconstruction...
Near-infrared optical imaging of the breast with model-based reconstructionHuabei Jiang
Department of Physics and Astronomy, Clemson University, SC 29634-0978, USA
Acad Radiol 9:186-94. 2002..In addition, preliminary data from the scattering images suggest that benign and malignant tumors can be noninvasively differentiated with optical imaging...
Model-based microwave image reconstruction: simulations and experimentsRazvan Ciocan
Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, USA
Med Phys 31:3231-41. 2004....
Measurement of particle size distribution in mammalian cells in vitro by use of polarized light spectroscopyMatthew Bartlett
Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, USA
Appl Opt 43:1296-307. 2004..Other subcellular structures, such as the nucleoli and the nucleus, may also contribute significantly. We reconstruct the PSD of the mitochondria, as verified by optical microscopy. We also demonstrate the angle dependence of the PSD...
Three-dimensional diffuse optical tomography of bones and jointsYong Xu
Clemson University, Biomedical Optics Laboratory, Department of Physics and Astronomy, Clemson, South Carolina 29634-0978, USA
J Biomed Opt 7:88-92. 2002..Our results show that 3D imaging methods can provide details of the joint structure/composition that would be impossible from two-dimensional imaging methods...
Measurement of particle size distribution in multilayered skin phantoms using polarized light spectroscopyMatthew Bartlett
Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, USA
Phys Rev E Stat Nonlin Soft Matter Phys 65:031906. 2002..In this paper we also study the effect of the thickness of the top layer on the ability to reconstruct the polystyrene size distribution...
Three-dimensional finite-element-based photoacoustic tomography: reconstruction algorithm and simulationsZhen Yuan
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
Med Phys 34:538-46. 2007..The results show that the algorithm is able to reconstruct photoacoustic images quantitatively in terms of the location, size, optical and acoustic properties of the target, and background media for various examples examined...
Image reconstruction scheme that combines modified Newton method and efficient initial guess estimation for optical tomography of finger jointsZhen Yuan
Department of Biomedical Engineering, University of Florida, FL 32611 6131, USA
Appl Opt 46:2757-68. 2007..The recovered results suggest that the improved approach is able to provide quantitatively better images than our previous algorithm for optical tomography reconstruction...
Three-dimensional diffuse optical tomography of osteoarthritis: initial results in the finger jointsZhen Yuan
University of Florida, Department of Biomedical Engineering, Gainesville, Florida 32611 6131, USA
J Biomed Opt 12:034001. 2007..The results of this pilot study show potential for quantitative imaging and diagnosis of early OA by DOT...
Quantitative bioluminescence tomography guided by diffuse optical tomographyQizhi Zhang
J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
Opt Express 16:1481-6. 2008....
Phase-contrast diffuse optical tomography pilot results in the breastXiaoping Liang
J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, 130 BME Building PO Box 116131, Gainesville, FL 32611
Acad Radiol 15:859-66. 2008....
Two-dimensional bioluminescence tomography: numerical simulations and phantom experimentsSenhu Li
Department of Biomedical Engineering, University of Florida, Gainesville, USA
Appl Opt 45:3390-4. 2006..The method is tested with numerical simulations and further confirmed with several phantom experiments...
Ultrasound-guided microwave imaging of breast cancer: tissue phantom and pilot clinical experimentsHuabei Jiang
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
Med Phys 32:2528-35. 2005..The pilot clinical studies on two cases suggest that breast tumors can be much more accurately detected by the multimodality method...
Imaging of small nanoparticle-containing objects by finite-element-based photoacoustic tomographyZhen Yuan
Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
Opt Lett 30:3054-6. 2005..The results obtained show that millimeter-size nanoparticle-containing objects can be clearly detected in terms of position, size, and relative optical properties...
Model-based ultrasound tomography: tissue phantom experimentsHongzhi Zhao
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, USA
Med Phys 32:2659-64. 2005..We also demonstrate that a high contrast target as small as 3 mm in diameter can be quantitatively resolved with our acoustic speed and attenuation images...
Finite-element-based photoacoustic tomography: phantom and chicken bone experimentsZhen Yuan
Department of Biomedical Engineering, University of Florida, Gainesville 32611 6131, USA
Appl Opt 45:3177-83. 2006..The results obtained show that millimeter-sized phantom objects and chicken bones and/or joints can be clearly detected using our finite-element-based photoacoustic tomography method...
Spatially varying optical and acoustic property reconstruction using finite-element-based photoacoustic tomographyHuabei Jiang
Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
J Opt Soc Am A Opt Image Sci Vis 23:878-88. 2006..The effect of acoustic heterogeneity on conventional pure optical absorption reconstruction is also studied...
Diffuse optical tomography guided quantitative fluorescence molecular tomographyYiyong Tan
J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, USA
Appl Opt 47:2011-6. 2008..In particular absolute value of mu(a(x-->m) ) from our DOT guided FMT are quantitatively consistent with that obtained using spectroscopic methods...
Quantitative reconstruction of refractive index distribution and imaging of glucose concentration by using diffusing lightXiaoping Liang
J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
Appl Opt 45:8360-5. 2006..The results show that the relative error of the reconstructed refractive index is reduced from 20% to within 1.5%. We also demonstrate the possibility of PCDOT for recovering glucose concentration using these phantom experiments...
A practical method for three-dimensional reconstruction of joints using a C-arm system and shift-and-add algorithmSenhu Li
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611-6131, USA
Med Phys 32:1491-9. 2005..The proposed method has been tested and evaluated on simulated cylinders, a chicken bone phantom with known structure, and an in vivo human index finger. The results are demonstrated and discussed...
Noninvasive in vivo tomographic optical imaging of cellular morphology in the breast: possible convergence of microscopic pathology and macroscopic radiologyChangqing Li
Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
Med Phys 35:2493-501. 2008..38 and 2.63. These initial results suggest that cellular mean size and volume fraction may be two new criteria that could be used to differentiate malignant from benign lesions...
Multispectral diffuse optical tomography with absorption and scattering spectral constraintsChangqing Li
J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611 6131, USA
Appl Opt 46:8229-36. 2007..The initial clinical results indicate that the volume fraction of scattering particles in a malignant tumor is higher than that in a benign tumor...
