Michael A J Zieger
Affiliation: Clarian Health Partners
- Endothelial cell fatty acid unsaturation mediates cold-induced oxidative stressMichael A J Zieger
Methodist Research Institute, Clarian Health Partners, Inc, Indianapolis, Indiana 46202, USA
J Cell Biochem 99:784-96. 2006..In conclusion, the findings implicate iron catalyzed free radicals and LPO as a predominant mechanism of endothelial cell injury at 0 degrees C, which may be reduced by increasing lipid saturation or treating cells with antioxidants...
- Endothelial cell preservation at 10 degrees C minimizes catalytic iron, oxidative stress, and cold-induced injuryMichael A J Zieger
Methodist Research Institute, Clarian Health Partners, Inc, Indianapolis, IN 46202, USA
Cell Transplant 15:499-510. 2006....
- Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent processMichael A J Zieger
Methodist Research Institute, Indianapolis, IN 46202, USA
Free Radic Biol Med 46:680-91. 2009..When HPC-mediated increases in ferritin were blocked by deferoxamine, protection at 0 degrees C was diminished. We conclude that HPC-mediated endothelial protection from hypothermic injury is an iron- and ferritin-dependent process...
- Proteomic analysis of endothelial cold-adaptationMichael A J Zieger
Methodist Research Institute, Indiana University Health, Indianapolis, IN 46202, USA
BMC Genomics 12:630. 2011....