C A Labarrere
Affiliation: Clarian Health Partners
- Early prediction of cardiac allograft vasculopathy and heart transplant failureC A Labarrere
Experimental Pathology, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN, USA
Am J Transplant 11:528-35. 2011..Early absence of atherothrombotic risk identifies a patient subgroup that rarely develops CAV or graft failure, implying that this low-risk subgroup could possibly be followed with fewer invasive procedures...
- Microvascular thrombosis and cardiac allograft vasculopathy in rat heart transplantationCarlos A Labarrere
Division of Experimental Pathology, Methodist Research Institute, Clarian Health Partners, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 25:1213-22. 2006..The aim of this study was to identify an animal model by which to further evaluate the role of coagulation in the pathogenesis of CAV...
- Syncytiotrophoblast intercellular adhesion molecule-1 expression in placental villitis of unknown causeCarlos A Labarrere
ImmunoPath, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, USA
Am J Obstet Gynecol 193:483-8. 2005..The purpose of this study was to determine syncytiotrophoblast intercellular adhesion molecule-1 expression in villitis and in normal chorionic villi from term (37-42 weeks of gestation) placentas with or without villitis...
- C-reactive protein: from innocent bystander to pivotal mediator of atherosclerosisCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners, Inc, Indianapolis, Indiana 46202, USA
Am J Med 117:499-507. 2004..We also discuss the evidence that C-reactive protein can injure arterial endothelium. Finally, we review therapies that target C-reactive protein for primary prevention and for the treatment of atherosclerotic diseases...
- C-reactive protein, arterial endothelial activation, and development of transplant coronary artery disease: a prospective studyCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners, Methodist, Indiana University, Riley Hospitals, Indianapolis, IN 46202, USA
Lancet 360:1462-7. 2002..We investigated whether C-reactive protein, known to stimulate ICAM-1, was associated with increased ICAM-1 concentration and subsequent development of coronary artery disease...
- Microvascular prothrombogenicity and transplant coronary artery diseaseCarlos A Labarrere
Methodist Research Institute at Clarian Health, Indianapolis, IN 46202, USA
Transpl Immunol 9:243-9. 2002..Reducing prothrombogenicity of the cardiac microvasculature early after transplantation could slow the development of transplant CAD and significantly improve allograft survival...
- Pathologic markers of allograft arteriopathy: insight into the pathophysiology of cardiac allograft chronic rejectionC A Labarrere
Methodist Research Institute, Clarian Health Partners, Methodist, Indiana University, Riley Hospitals, 1701 N Senate Blvd, Indianapolis, IN 46202, USA
Curr Opin Cardiol 16:110-7. 2001..New therapies that could improve the status of the allograft microvasculature and may prevent or mitigate the development of transplant-associated CAD are considered...
- Vascular antithrombin and clinical outcome in heart transplant patientsC A Labarrere
Methodist Research Institute, Methodist Transplant Center, Indiana University, Riley Hospitals, Indianapolis 46202, USA
Am J Cardiol 87:425-31. 2001..However, recovery of vascular antithrombin and development of unusual capillary antithrombin binding improves allograft outcome...
- Cardiac-specific troponin I levels and risk of coronary artery disease and graft failure following heart transplantationC A Labarrere
Methodist Research Institute, Clarian Health, 1812 N Capitol Ave, Indianapolis, IN 46202, USA
JAMA 284:457-64. 2000..Previous studies have yielded conflicting data regarding whether a relationship exists between elevated cardiac troponin levels and acute allograft rejection in patients who have received heart transplants...
- Conduct unbecoming: C-reactive protein interactions with a broad range of protein moleculesGeorge Boguslawski
Methodist Research Institute, Clarian Health Partners, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 26:705-13. 2007..Understanding the biology of CRP may be relevant to understanding atherosclerosis development and progression...
- Non-immunologic vascular failure of the transplanted heartCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners Methodist, Indiana University and Riley Hospitals, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 22:236-40. 2003
- Continuously-infused human C-reactive protein is neither proatherosclerotic nor proinflammatory in apolipoprotein E-deficient miceMiguel A Ortiz
Methodist Research Institute, Clarian Health, 1800 N Capitol Avenue, Suite E504A, Indianapolis, IN 46202, USA
Exp Biol Med (Maywood) 234:624-31. 2009....
- Precision of biomarkers to define chronic inflammation in CKDRobert LaClair
Indiana University School of Medicine, Indianapolis, Indiana, USA
Am J Nephrol 28:808-12. 2008..The purpose of the present study was to determine the intrapatient variation of C-reactive protein, IL-6, fetuin-A and albumin in a population of dialysis patients...
- Expression of a novel high molecular-weight myosin light chain kinase in endotheliumA D Verin
Department of Medicine, Physiology and Biophysics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Am J Respir Cell Mol Biol 19:758-66. 1998..These data suggest that the novel 214-kD kinase, the only MLCK isoform found in endothelium, may be preferentially expressed in this nonmuscle tissue...
- Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growthMatthew R Distasi
Department of Cellular and Integrative Physiology, Indiana Univ School of Medicine, 1001 W 10th St, WD OPW 425 E, Indianapolis, IN 46202, USA
Am J Physiol Heart Circ Physiol 296:H877-86. 2009..These novel results indicate that collateral luminal expansion and intimal cell recruitment/proliferation are not mediated by Rac2 and Nox2...
- Development of progressive aortic vasculopathy in a rat model of agingSteven J Miller
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 2879, USA
Am J Physiol Heart Circ Physiol 293:H2634-43. 2007..The results demonstrate that major structural abnormalities and altered gene expression develop after 6 mo and that the progressive pathological development is associated with increased inflammation and oxidant stress...
- Changes in myocardial vasoreactivity after drastic reduction of plasma fibrinogen and cholesterol: a clinical study in long-term heart transplant survivors using positron emission tomographyBeate R Jaeger
Institut fur Klinische Chemie, Klinikum der Universitat Munchen, Munchen, Germany
J Heart Lung Transplant 24:2022-30. 2005....