C A Labarrere
Affiliation: Clarian Health Partners
- C-reactive protein: from innocent bystander to pivotal mediator of atherosclerosisCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners, Inc, Indianapolis, Indiana 46202, USA
Am J Med 117:499-507. 2004..We also discuss the evidence that C-reactive protein can injure arterial endothelium. Finally, we review therapies that target C-reactive protein for primary prevention and for the treatment of atherosclerotic diseases...
- Microvascular prothrombogenicity and transplant coronary artery diseaseCarlos A Labarrere
Methodist Research Institute at Clarian Health, Indianapolis, IN 46202, USA
Transpl Immunol 9:243-9. 2002..Reducing prothrombogenicity of the cardiac microvasculature early after transplantation could slow the development of transplant CAD and significantly improve allograft survival...
- C-reactive protein, arterial endothelial activation, and development of transplant coronary artery disease: a prospective studyCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners, Methodist, Indiana University, Riley Hospitals, Indianapolis, IN 46202, USA
Lancet 360:1462-7. 2002..We investigated whether C-reactive protein, known to stimulate ICAM-1, was associated with increased ICAM-1 concentration and subsequent development of coronary artery disease...
- Microvascular thrombosis and cardiac allograft vasculopathy in rat heart transplantationCarlos A Labarrere
Division of Experimental Pathology, Methodist Research Institute, Clarian Health Partners, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 25:1213-22. 2006..The aim of this study was to identify an animal model by which to further evaluate the role of coagulation in the pathogenesis of CAV...
- Early prediction of cardiac allograft vasculopathy and heart transplant failureC A Labarrere
Experimental Pathology, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN, USA
Am J Transplant 11:528-35. 2011..Early absence of atherothrombotic risk identifies a patient subgroup that rarely develops CAV or graft failure, implying that this low-risk subgroup could possibly be followed with fewer invasive procedures...
- Syncytiotrophoblast intercellular adhesion molecule-1 expression in placental villitis of unknown causeCarlos A Labarrere
ImmunoPath, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, USA
Am J Obstet Gynecol 193:483-8. 2005..The purpose of this study was to determine syncytiotrophoblast intercellular adhesion molecule-1 expression in villitis and in normal chorionic villi from term (37-42 weeks of gestation) placentas with or without villitis...
- Pathologic markers of allograft arteriopathy: insight into the pathophysiology of cardiac allograft chronic rejectionC A Labarrere
Methodist Research Institute, Clarian Health Partners, Methodist, Indiana University, Riley Hospitals, 1701 N Senate Blvd, Indianapolis, IN 46202, USA
Curr Opin Cardiol 16:110-7. 2001..New therapies that could improve the status of the allograft microvasculature and may prevent or mitigate the development of transplant-associated CAD are considered...
- Vascular antithrombin and clinical outcome in heart transplant patientsC A Labarrere
Methodist Research Institute, Methodist Transplant Center, Indiana University, Riley Hospitals, Indianapolis 46202, USA
Am J Cardiol 87:425-31. 2001..However, recovery of vascular antithrombin and development of unusual capillary antithrombin binding improves allograft outcome...
- Cardiac-specific troponin I levels and risk of coronary artery disease and graft failure following heart transplantationC A Labarrere
Methodist Research Institute, Clarian Health, 1812 N Capitol Ave, Indianapolis, IN 46202, USA
JAMA 284:457-64. 2000..Previous studies have yielded conflicting data regarding whether a relationship exists between elevated cardiac troponin levels and acute allograft rejection in patients who have received heart transplants...
- Conduct unbecoming: C-reactive protein interactions with a broad range of protein moleculesGeorge Boguslawski
Methodist Research Institute, Clarian Health Partners, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 26:705-13. 2007..Understanding the biology of CRP may be relevant to understanding atherosclerosis development and progression...
- Continuously-infused human C-reactive protein is neither proatherosclerotic nor proinflammatory in apolipoprotein E-deficient miceMiguel A Ortiz
Methodist Research Institute, Clarian Health, 1800 N Capitol Avenue, Suite E504A, Indianapolis, IN 46202, USA
Exp Biol Med (Maywood) 234:624-31. 2009....
- Non-immunologic vascular failure of the transplanted heartCarlos A Labarrere
Methodist Research Institute, Clarian Health Partners Methodist, Indiana University and Riley Hospitals, Indianapolis, Indiana 46202, USA
J Heart Lung Transplant 22:236-40. 2003
- Precision of biomarkers to define chronic inflammation in CKDRobert LaClair
Indiana University School of Medicine, Indianapolis, Indiana, USA
Am J Nephrol 28:808-12. 2008..The purpose of the present study was to determine the intrapatient variation of C-reactive protein, IL-6, fetuin-A and albumin in a population of dialysis patients...
- Intercellular adhesion molecule-1 expression in massive chronic intervillositis: Implications for the invasion of maternal cells into fetal tissuesC A Labarrere
CBL Partners for Life, Indianapolis, IN, United States Indiana University School of Medicine, Indianapolis, IN, United States Indiana University Health Methodist Research Institute, Indianapolis, IN, United States Electronic address
Placenta 35:311-7. 2014....
- Expression of a novel high molecular-weight myosin light chain kinase in endotheliumA D Verin
Department of Medicine, Physiology and Biophysics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Am J Respir Cell Mol Biol 19:758-66. 1998..These data suggest that the novel 214-kD kinase, the only MLCK isoform found in endothelium, may be preferentially expressed in this nonmuscle tissue...
- Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growthMatthew R Distasi
Department of Cellular and Integrative Physiology, Indiana Univ School of Medicine, 1001 W 10th St, WD OPW 425 E, Indianapolis, IN 46202, USA
Am J Physiol Heart Circ Physiol 296:H877-86. 2009..These novel results indicate that collateral luminal expansion and intimal cell recruitment/proliferation are not mediated by Rac2 and Nox2...
- Development of progressive aortic vasculopathy in a rat model of agingSteven J Miller
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 2879, USA
Am J Physiol Heart Circ Physiol 293:H2634-43. 2007..The results demonstrate that major structural abnormalities and altered gene expression develop after 6 mo and that the progressive pathological development is associated with increased inflammation and oxidant stress...
- Changes in myocardial vasoreactivity after drastic reduction of plasma fibrinogen and cholesterol: a clinical study in long-term heart transplant survivors using positron emission tomographyBeate R Jaeger
Institut fur Klinische Chemie, Klinikum der Universitat Munchen, Munchen, Germany
J Heart Lung Transplant 24:2022-30. 2005....