Jeffrey D Altenburg

Summary

Affiliation: Clarian Health Partners
Country: USA

Publications

  1. pmc A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, Indiana, USA
    BMC Cancer 11:149. 2011
  2. doi Docosahexaenoic acid downregulates interferon gamma-induced expression of CXCL16 in human aortic smooth muscle cells
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, United States
    Biochem Biophys Res Commun 391:609-14. 2010
  3. doi Docosahexaenoic acid: a natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects
    Rafat A Siddiqui
    Cellular Biochemistry Laboratory, Indiana University Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biofactors 37:399-412. 2011
  4. pmc The potent anti-HIV activity of CXCL12gamma correlates with efficient CXCR4 binding and internalization
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Virol 84:2563-72. 2010
  5. doi A novel 2,6-diisopropylphenyl-docosahexaenoamide conjugate induces apoptosis in T cell acute lymphoblastic leukemia cell lines
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, IN 46202, USA
    Biochem Biophys Res Commun 411:427-32. 2011
  6. doi Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, USA
    Mol Cancer Res 7:1013-20. 2009
  7. pmc Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells
    Justin Vanhorn
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indianapolis
    J Inflamm Res 5:37-50. 2012
  8. pmc A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, 635 Barnhill Drive, Room 420, Indianapolis, IN 46202, USA
    J Virol 81:8140-8. 2007

Collaborators

Detail Information

Publications8

  1. pmc A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, Indiana, USA
    BMC Cancer 11:149. 2011
    ....
  2. doi Docosahexaenoic acid downregulates interferon gamma-induced expression of CXCL16 in human aortic smooth muscle cells
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, United States
    Biochem Biophys Res Commun 391:609-14. 2010
    ..These findings may prove to be important in other disease fields that identify IFNgamma as a regulator...
  3. doi Docosahexaenoic acid: a natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects
    Rafat A Siddiqui
    Cellular Biochemistry Laboratory, Indiana University Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biofactors 37:399-412. 2011
    ..Use of DHA with anticancer treatments provides an avenue to therapeutic improvement that involves less risk or side effects for patients and reduced regulatory burden for implementation...
  4. pmc The potent anti-HIV activity of CXCL12gamma correlates with efficient CXCR4 binding and internalization
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Virol 84:2563-72. 2010
    ..We concluded that the observed potent anti-HIV-1 activity of CXCL12gamma is due to increased affinity for CXCR4 and to efficient receptor internalization...
  5. doi A novel 2,6-diisopropylphenyl-docosahexaenoamide conjugate induces apoptosis in T cell acute lymphoblastic leukemia cell lines
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, IN 46202, USA
    Biochem Biophys Res Commun 411:427-32. 2011
    ..These conjugates have potential use for treatment of patients with T cell acute lymphoblastic leukemia...
  6. doi Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells
    Jeffrey D Altenburg
    Cellular Biochemistry Laboratory, Methodist Research Institute, Clarian Health Partners, Indianapolis, IN 46202, USA
    Mol Cancer Res 7:1013-20. 2009
    ..This suggests a previously unreported potential benefit of n-3 PUFAs to patients with metastatic breast cancer. The data presented in this study may also translate to other disorders that involve up-regulated chemokine receptors...
  7. pmc Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells
    Justin Vanhorn
    Cellular Biochemistry Laboratory, Methodist Research Institute, Indianapolis
    J Inflamm Res 5:37-50. 2012
    ..In conclusion, this study suggests that the regular use of omega-3 PUFAs along with niacin can potentially reduce the niacin-induced flushing response in sensitive patients...
  8. pmc A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, 635 Barnhill Drive, Room 420, Indianapolis, IN 46202, USA
    J Virol 81:8140-8. 2007
    ....