Research Topics
Genomes and GenesSpecies | Sophia S WangSummaryAffiliation: City of Hope National Medical Center Country: USA Publications
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Detail Information
Publications
Variation in effects of non-Hodgkin lymphoma risk factors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestral haplotype 8.1Sophia S Wang
Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, Duarte, California, United States of America
PLoS ONE 6:e26949. 2011....- HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancerRosemary E Zuna
Department of Pathology, University of Oklahoma Health Sciences Center, 940 SL Young Blvd, Oklahoma City, Oklahoma, 73104 5042, USA
Infect Agent Cancer 6:19. 2011..abstract:.. 
Cervical cancer incidence among 6 asian ethnic groups in the United States, 1996 through 2004Sophia S Wang
Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
Cancer 116:949-56. 2010..Cervical cancer incidence was evaluated by histologic type, age at diagnosis, and disease stage for 6 Asian ethnic groups residing in the United States...- Common genetic variants and risk for HPV persistence and progression to cervical cancerSophia S Wang
Division of Etiology, City of Hope National Medical Center, Duarte, California, USA
PLoS ONE 5:e8667. 2010..Our results require replication but suggest that different genes may be responsible for modulating risk in the two critical transition steps important for cervical carcinogenesis: HPV persistence and disease progression... - Unraveling the interactions between environmental factors and genetic polymorphisms in non-Hodgkin lymphoma riskSophia S Wang
Division of Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Expert Rev Anticancer Ther 10:403-13. 2010..This will require large consortial efforts to attain adequate sample size and power to detect meaningful biological and statistical interactions... - Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiologySophia S Wang
Division of Cancer Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
Blood 115:4820-3. 2010..01 for elevated risk with increasing number of homozygous alleles). Our results support a role for HLA in the etiology of NHL and its subtypes... - Joint associations between genetic variants and reproductive factors in glioma risk among womenSophia S Wang
Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and the City of Hope, Duarte, CA 91010, USA
Am J Epidemiol 174:901-8. 2011..These results require replication, but if confirmed, they would suggest that the gene variants that have previously been implicated in the development of glioma are unlikely to act through the same hormonal mechanisms in women... - Variations in chromosomes 9 and 6p21.3 with risk of non-Hodgkin lymphomaSophia S Wang
Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, 500 Duarte Road, Duarte, CA 9101, USA
Cancer Epidemiol Biomarkers Prev 20:42-9. 2011..To complement ongoing agnostic approaches for identifying susceptibility genes, we evaluated 488 candidate gene regions and their relation to risk for NHL and NHL subtypes... - Human leukocyte antigen class I and II alleles and overall survival in diffuse large B-cell lymphoma and follicular lymphomaYani Lu
Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
ScientificWorldJournal 11:2062-70. 2011..36, 95% CI = 0.20-0.63) with better OS among FL patients. These results support a role for HLA in the prognosis of DLBCL and FL and represent a promising class of prognostic factors that warrants further evaluation... - Oral contraceptives, menopausal hormone therapy use and risk of B-cell non-Hodgkin lymphoma in the California Teachers StudyYani Lu
Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
Int J Cancer 129:974-82. 2011..15, 95% CI=1.62-6.13). Bilateral oophorectomy plus hysterectomy was not associated with risk among women who used ET or EPT. These results indicate that exogenous hormone use does not strongly influence B-cell NHL risk... - Cigarette smoking, passive smoking, and non-Hodgkin lymphoma risk: evidence from the California Teachers StudyYani Lu
Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
Am J Epidemiol 174:563-73. 2011..89 (95% CI: 1.23, 6.80); P for trend = 0.01). The present study provides evidence that smoking and passive smoking may influence NHL etiology, particularly for follicular lymphoma... - Parents' ages at birth and risk of adult-onset hematologic malignancies among female teachers in CaliforniaYani Lu
Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
Am J Epidemiol 171:1262-9. 2010..Advanced paternal age may play a role in non-Hodgkin lymphoma etiology. Potential etiologic mechanisms include de novo gene mutations, aberrant paternal gene imprinting, or telomere/telomerase biology... - Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32Lucia Conde
School of Public Health, University of California, Berkeley, Berkeley, California, USA
Nat Genet 42:661-4. 2010..We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 x 10(-9))...