Sophia S Wang

Summary

Affiliation: City of Hope National Medical Center
Country: USA

Publications

  1. pmc Medical history, lifestyle, family history, and occupational risk factors for peripheral T-cell lymphomas: the InterLymph Non-Hodgkin Lymphoma Subtypes Project
    Sophia S Wang
    Department of Cancer Etiology, Beckman Research Institute of the City of Hope, Duarte, CA SSW Winship Cancer Institute, Emory University, Atlanta, GA CRF Department of Dermatology, Boston University, Boston, MA, Roger Williams Medical Center, Providence, RI MEK Health Sciences Practice, Exponent, Inc, Menlo Park, CA, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA ETC National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia AMH Department of Health Sciences Research, Mayo Clinic, Rochester, MN SMA Department of Laboratory Medicine and Pathology, Mayo Clinic Cancer Center, Rochester, MN ALF Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK TL Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY PB Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark MM Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD QL, JNS, LMM Department of Environmental Health Sciences, Academic Hospital Maastricht
    J Natl Cancer Inst Monogr 2014:66-75. 2014
  2. pmc Anthropometric, behavioral, and female reproductive factors and risk of multiple myeloma: a pooled analysis
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, City of Hope and the Beckman Research Institute, Duarte, CA 91010, USA
    Cancer Causes Control 24:1279-89. 2013
  3. pmc Variation in effects of non-Hodgkin lymphoma risk factors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestral haplotype 8.1
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, Duarte, California, United States of America
    PLoS ONE 6:e26949. 2011
  4. pmc HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer
    Rosemary E Zuna
    Department of Pathology, University of Oklahoma Health Sciences Center, 940 SL Young Blvd, Oklahoma City, Oklahoma, 73104 5042, USA
    Infect Agent Cancer 6:19. 2011
  5. pmc Joint associations between genetic variants and reproductive factors in glioma risk among women
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and the City of Hope, Duarte, CA 91010, USA
    Am J Epidemiol 174:901-8. 2011
  6. pmc Common genetic variants and risk for HPV persistence and progression to cervical cancer
    Sophia S Wang
    Division of Etiology, City of Hope National Medical Center, Duarte, California, USA
    PLoS ONE 5:e8667. 2010
  7. doi request reprint Unraveling the interactions between environmental factors and genetic polymorphisms in non-Hodgkin lymphoma risk
    Sophia S Wang
    Division of Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Expert Rev Anticancer Ther 10:403-13. 2010
  8. pmc Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
    Blood 115:4820-3. 2010
  9. pmc Variations in chromosomes 9 and 6p21.3 with risk of non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, 500 Duarte Road, Duarte, CA 9101, USA
    Cancer Epidemiol Biomarkers Prev 20:42-9. 2011
  10. doi request reprint Cervical cancer incidence among 6 asian ethnic groups in the United States, 1996 through 2004
    Sophia S Wang
    Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
    Cancer 116:949-56. 2010

Detail Information

Publications70

  1. pmc Medical history, lifestyle, family history, and occupational risk factors for peripheral T-cell lymphomas: the InterLymph Non-Hodgkin Lymphoma Subtypes Project
    Sophia S Wang
    Department of Cancer Etiology, Beckman Research Institute of the City of Hope, Duarte, CA SSW Winship Cancer Institute, Emory University, Atlanta, GA CRF Department of Dermatology, Boston University, Boston, MA, Roger Williams Medical Center, Providence, RI MEK Health Sciences Practice, Exponent, Inc, Menlo Park, CA, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA ETC National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia AMH Department of Health Sciences Research, Mayo Clinic, Rochester, MN SMA Department of Laboratory Medicine and Pathology, Mayo Clinic Cancer Center, Rochester, MN ALF Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK TL Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY PB Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark MM Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD QL, JNS, LMM Department of Environmental Health Sciences, Academic Hospital Maastricht
    J Natl Cancer Inst Monogr 2014:66-75. 2014
    ..Our aim was to identify etiologic risk factors for PTCL overall, and for specific PTCL subtypes, by analyzing data from 15 epidemiologic studies participating in the InterLymph Consortium...
  2. pmc Anthropometric, behavioral, and female reproductive factors and risk of multiple myeloma: a pooled analysis
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, City of Hope and the Beckman Research Institute, Duarte, CA 91010, USA
    Cancer Causes Control 24:1279-89. 2013
    ....
  3. pmc Variation in effects of non-Hodgkin lymphoma risk factors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestral haplotype 8.1
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, Duarte, California, United States of America
    PLoS ONE 6:e26949. 2011
    ....
  4. pmc HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer
    Rosemary E Zuna
    Department of Pathology, University of Oklahoma Health Sciences Center, 940 SL Young Blvd, Oklahoma City, Oklahoma, 73104 5042, USA
    Infect Agent Cancer 6:19. 2011
    ..abstract:..
  5. pmc Joint associations between genetic variants and reproductive factors in glioma risk among women
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and the City of Hope, Duarte, CA 91010, USA
    Am J Epidemiol 174:901-8. 2011
    ..These results require replication, but if confirmed, they would suggest that the gene variants that have previously been implicated in the development of glioma are unlikely to act through the same hormonal mechanisms in women...
  6. pmc Common genetic variants and risk for HPV persistence and progression to cervical cancer
    Sophia S Wang
    Division of Etiology, City of Hope National Medical Center, Duarte, California, USA
    PLoS ONE 5:e8667. 2010
    ..Our results require replication but suggest that different genes may be responsible for modulating risk in the two critical transition steps important for cervical carcinogenesis: HPV persistence and disease progression...
  7. doi request reprint Unraveling the interactions between environmental factors and genetic polymorphisms in non-Hodgkin lymphoma risk
    Sophia S Wang
    Division of Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Expert Rev Anticancer Ther 10:403-13. 2010
    ..This will require large consortial efforts to attain adequate sample size and power to detect meaningful biological and statistical interactions...
  8. pmc Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
    Blood 115:4820-3. 2010
    ..01 for elevated risk with increasing number of homozygous alleles). Our results support a role for HLA in the etiology of NHL and its subtypes...
  9. pmc Variations in chromosomes 9 and 6p21.3 with risk of non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute and City of Hope, 500 Duarte Road, Duarte, CA 9101, USA
    Cancer Epidemiol Biomarkers Prev 20:42-9. 2011
    ..To complement ongoing agnostic approaches for identifying susceptibility genes, we evaluated 488 candidate gene regions and their relation to risk for NHL and NHL subtypes...
  10. doi request reprint Cervical cancer incidence among 6 asian ethnic groups in the United States, 1996 through 2004
    Sophia S Wang
    Division of Etiology, Department of Population Sciences, City of Hope, Duarte, CA 91010, USA
    Cancer 116:949-56. 2010
    ..Cervical cancer incidence was evaluated by histologic type, age at diagnosis, and disease stage for 6 Asian ethnic groups residing in the United States...
  11. ncbi request reprint Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma
    Qing Lan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, EPS 8109, Bethesda, MD 20892 7240, USA
    Hum Genet 121:161-8. 2007
    ..013), but was also associated with non-significant increased risks for each of the common B-cell histologies. These results suggest that SNPs in genes related to the oxidative stress pathway may be associated with increased risk of NHL...
  12. ncbi request reprint Comprehensive analysis of human leukocyte antigen class I alleles and cervical neoplasia in 3 epidemiologic studies
    Sophia S Wang
    Interdisciplinary Studies Section, Division of Cancer Epidemiology and Genetics, Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892 7234, USA
    J Infect Dis 186:598-605. 2002
    ..Given the relationship between HLA-C and its receptors on natural killer (NK) cells, a role is proposed for NK function in human papillomavirus infection and cervical neoplasia...
  13. pmc Common genetic variation in TP53 and risk of human papillomavirus persistence and progression to CIN3/cancer revisited
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7248, USA
    Cancer Epidemiol Biomarkers Prev 18:1631-7. 2009
    ..Although genetic variation in TP53 might affect the natural history of HPV and cervical cancer, further work is needed to elucidate the possible mechanism...
  14. ncbi request reprint Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20892 7234, USA
    Cancer Res 66:9771-80. 2006
    ..Our results require replication but potentially provide important clues for investigating common genetic variants as susceptibility factors and in disease outcomes, treatment responses, and immunotherapy targets...
  15. pmc Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development
    Lindsay M Morton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 18:1259-70. 2009
    ..Replication of our findings and further study to identify functional SNPs are warranted...
  16. pmc Human papillomavirus cofactors by disease progression and human papillomavirus types in the study to understand cervical cancer early endpoints and determinants
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 5104, Rockville, MD 20854 7234, USA
    Cancer Epidemiol Biomarkers Prev 18:113-20. 2009
    ..Investigations on the molecular distinctions along the disease continuum of cervical pathogenesis by HPV type are needed...
  17. pmc Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer
    Sophia S Wang
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 5104, Rockville, MD 20852 7234, USA
    J Infect Dis 199:20-30. 2009
    ..We examined host genetic factors to identify those more common in individuals whose human papillomavirus (HPV) infections were most likely to persist and progress to cervical intraepithelial neoplasia grade 3 (CIN3) and cancer...
  18. ncbi request reprint Validation of p16INK4a as a marker of oncogenic human papillomavirus infection in cervical biopsies from a population-based cohort in Costa Rica
    Sophia S Wang
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS MSC 7234, Bethesda, MD 20892 7234, USA
    Cancer Epidemiol Biomarkers Prev 13:1355-60. 2004
    ..Whereas our data support the diagnostic potential for p16INK4a, further prospective studies with detailed follow-up determining the prognostic capacity of this marker are needed...
  19. ncbi request reprint Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphoma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8009, Rockville, MD 20892, USA
    Cancer Causes Control 18:989-99. 2007
    ....
  20. ncbi request reprint Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Immunogenetics 59:839-52. 2007
    ..25). These results suggest that there is substantial genetic diversity in immune genes and exploration of SNP associations with immune-related diseases that vary in incidence across these two populations may be warranted...
  21. pmc Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies
    Min Shen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Br J Haematol 151:239-44. 2010
    ..These results support the hypothesis that common genetic polymorphisms in human DNA repair genes may modify the risk of NHL...
  22. pmc Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma
    Lindsay M Morton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Carcinogenesis 28:1759-64. 2007
    ..Several previous studies have found non-Hodgkin lymphoma (NHL) risk to be associated with hair dye use, particularly use of permanent, dark colors and use before 1980, when hair dye formulations changed...
  23. ncbi request reprint Immune mechanisms in non-Hodgkin lymphoma: joint effects of the TNF G308A and IL10 T3575A polymorphisms with non-Hodgkin lymphoma risk factors
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892 7234, USA
    Cancer Res 67:5042-54. 2007
    ....
  24. pmc Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
    Sonja I Berndt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Bethesda, Maryland, USA
    Nat Genet 45:868-76. 2013
    ..3 (ODF1, P=5.40×10(-8)) and 5p15.33 (TERT, P=1.92×10(-7)). Although further studies are required, the proximity of several of these loci to genes involved in apoptosis suggests a plausible underlying biological mechanism...
  25. pmc Single nucleotide polymorphisms in the PRDX3 and RPS19 and risk of HPV persistence and cervical precancer/cancer
    Mahboobeh Safaeian
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 7:e33619. 2012
    ..Host genetic factors might affect the risk of progression from infection with carcinogenic human papillomavirus (HPV), the etiologic agent for cervical cancer, to persistent HPV infection, and hence to cervical precancer and cancer...
  26. pmc Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut
    Kyoung Mu Lee
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Am J Hematol 85:560-3. 2010
    ..Additional studies are needed to replicate these findings and, more generally, to explore the manner in which genes and receptors may influence the pathogenesis of this poorly understood malignancy...
  27. pmc Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Blood 113:1899-905. 2009
    ..This shows that the relation between organochlorine exposure and NHL risk may be modified by particular variants in immune genes and provides one of the first examples of a potential gene-environment interaction for NHL...
  28. pmc Grading the severity of cervical neoplasia based on combined histopathology, cytopathology, and HPV genotype distribution among 1,700 women referred to colposcopy in Oklahoma
    Nicolas Wentzensen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20854 7234, USA
    Int J Cancer 124:964-9. 2009
    ..We are now using these sharpened diagnostic categories to search for novel biomarkers predicting the risk of progression and invasion...
  29. pmc Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
    PLoS ONE 4:e5360. 2009
    ..We hypothesized that the TNF and NF-kappaB pathways are important for NHL and that gene variations across the pathways may alter NHL risk...
  30. pmc Vegetables- and antioxidant-related nutrients, genetic susceptibility, and non-Hodgkin lymphoma risk
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
    Cancer Causes Control 19:491-503. 2008
    ..Although most associations have not been examined previously with NHL, our results suggest the examined polymorphisms are not modifiers of the association between vegetable and zinc intakes and NHL risk...
  31. ncbi request reprint Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma among women in Connecticut
    Min Shen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    Hum Genet 119:659-68. 2006
    ..Further work is needed to extend these findings by carrying out extended haplotype analyses of these and related genes and to replicate the observations in other studies...
  32. pmc Genetic variation in Th1/Th2 pathway genes and risk of non-Hodgkin lymphoma: a pooled analysis of three population-based case-control studies
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Br J Haematol 153:341-50. 2011
    ..This SNP was also associated specifically with risk of follicular lymphoma (allele risk OR= 1·26; P(trend)= 0·0012). These findings suggest that genetic variation in Th1/Th2 cytokine genes may contribute to lymphomagenesis...
  33. pmc Incidence of lymphoid neoplasms by subtype among six Asian ethnic groups in the United States, 1996-2004
    J Daniel Carreon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Cancer Causes Control 19:1171-81. 2008
    ..To establish baseline data for lymphoid neoplasm incidence by subtype for six Asian-American ethnic groups...
  34. pmc Heterogeneity of high-grade cervical intraepithelial neoplasia related to HPV16: implications for natural history and management
    Nicolas Wentzensen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
    Int J Cancer 132:148-54. 2013
    ..Lesion size seems to be an important determinant of colposcopy and biopsy performance. Genotyping for HPV16 in cervical cancer screening can improve risk stratification but may pose challenges to finding small lesions in colposcopy...
  35. ncbi request reprint Common variants in genes that mediate immunity and risk of multiple myeloma
    Elizabeth E Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 120:2715-22. 2007
    ..Our findings provide preliminary evidence that common genetic variants in specific immune-mediated pathways could influence the risk of MM...
  36. pmc Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Blood 114:264-7. 2009
    ..It is noteworthy that genetic variants in CASP8 were associated with risk of all major NHL subtypes. Our findings suggest that genetic variation in caspases may play an important role in lymphomagenesis...
  37. pmc Accuracy of cervical specimens obtained for biomarker studies in women with CIN3
    Nicolas Wentzensen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 5014, Rockville, MD 20854 7234, USA
    Gynecol Oncol 115:493-6. 2009
    ..We developed a protocol to collect representative cervical specimens based on colposcopic evaluation from women treated with loop electrosurgical excision procedure (LEEP)...
  38. ncbi request reprint Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    Carcinogenesis 27:1828-34. 2006
    ....
  39. pmc SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Elizabeth M Azzato
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
    BMC Med Genet 10:9. 2009
    ....
  40. ncbi request reprint Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan
    Allan Hildesheim
    Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rm 7062, Rockville, MD 20852, USA
    J Natl Cancer Inst 94:1780-9. 2002
    ..We used high-resolution HLA genotyping in a case-control study in Taiwan to systematically evaluate the association between various HLA alleles and NPC...
  41. pmc Parents' ages at birth and risk of adult-onset hematologic malignancies among female teachers in California
    Yani Lu
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
    Am J Epidemiol 171:1262-9. 2010
    ..Advanced paternal age may play a role in non-Hodgkin lymphoma etiology. Potential etiologic mechanisms include de novo gene mutations, aberrant paternal gene imprinting, or telomere/telomerase biology...
  42. pmc Common variation in genes related to innate immunity and risk of adult glioma
    Preetha Rajaraman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 18:1651-8. 2009
    ..We have identified a promising set of innate immunity-related genetic regions for further investigation...
  43. ncbi request reprint Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma
    Qing Lan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, DHHS, Bethesda, MD 20892 7240, USA
    Carcinogenesis 28:823-7. 2007
    ..The striking protective associations observed for polymorphisms in all four genes for NHL and/or one or more subtypes suggest that genetic variation in CASP genes may play an important role in the etiology of NHL...
  44. pmc A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Carcinogenesis 30:275-81. 2009
    ..No associations with TLR4 variants were observed. This pooled analysis provides strong evidence that variation in the TLR10-TLR1-TLR6 region is associated with NHL risk and suggests that TLR2 variants may influence susceptibility to MZL...
  45. pmc Human leukocyte antigen class I and II alleles and overall survival in diffuse large B-cell lymphoma and follicular lymphoma
    Yani Lu
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
    ScientificWorldJournal 11:2062-70. 2011
    ..36, 95% CI = 0.20-0.63) with better OS among FL patients. These results support a role for HLA in the prognosis of DLBCL and FL and represent a promising class of prognostic factors that warrants further evaluation...
  46. pmc Smoking, alcohol use, obesity, and overall survival from non-Hodgkin lymphoma: a population-based study
    Susan M Geyer
    Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Cancer 116:2993-3000. 2010
    ..Smoking, alcohol use, and obesity appear to increase the risk of developing non-Hodgkin lymphoma (NHL), but to the authors' knowledge, few studies to date have assessed their impact on NHL prognosis...
  47. ncbi request reprint Cyclin D1 splice variant and risk for non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS MSC 7234, Bethesda, Rockville, MD 20892 7234, USA
    Hum Genet 120:297-300. 2006
    ..4, 95% CI = 1.1-1.8, P-trend = 0.021), which was consistent for four B-cell subtypes. As CCND1 expression indicates poor NHL prognosis, our results, if true, would support its potentially dual importance in NHL etiology and survival...
  48. pmc Human papillomavirus load measured by Linear Array correlates with quantitative PCR in cervical cytology specimens
    Nicolas Wentzensen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    J Clin Microbiol 50:1564-70. 2012
    ..Our findings support conducting comprehensive studies of viral load and cervical cancer precursors using quantitative LA genotyping data...
  49. pmc Relationship between interferon regulatory factor 4 genetic polymorphisms, measures of sun sensitivity and risk for non-Hodgkin lymphoma
    Allison H Gathany
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 20:1291-302. 2009
    ..We evaluated the independent roles of these IRF4 polymorphisms and sun sensitivity in mediating NHL risk and explored whether they are confounded or modified by each other...
  50. ncbi request reprint Determinants of human papillomavirus load among women with histological cervical intraepithelial neoplasia 3: dominant impact of surrounding low-grade lesions
    Mark E Sherman
    Department of Health and Human Services, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland 20892 7374, USA
    Cancer Epidemiol Biomarkers Prev 12:1038-44. 2003
    ..These factors severely limit the clinical use of load measurements irrespective of HPV testing methodology...
  51. pmc Risk of meningioma and common variation in genes related to innate immunity
    Preetha Rajaraman
    Division of Cancer Epidemiology and Genetics, Neuro Oncology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7058, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 19:1356-61. 2010
    ..The etiology of meningioma, the second most common type of adult brain tumor in the United States, is largely unknown. Prior studies indicate that history of immune-related conditions may affect the risk of meningioma...
  52. pmc Reproducibility of linear array for human papillomavirus genotyping
    Jill Koshiol
    Division of Cancer Epidemiology and Genetics, NCI NIH DHHS, Bethesda, Maryland, USA
    J Clin Microbiol 51:625-8. 2013
    ..3% overall [Kappa = 0.9] and 86.8% for carcinogenic types [Kappa = 0.92]). Discordance was highest with a low hybridization signal strength. Overall, Linear Array was highly reproducible...
  53. ncbi request reprint Genetic variation in catechol-O-methyltransferase (COMT) and obesity in the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS 5104, MSC 7234, Rockville, MD 20852, USA
    Hum Genet 122:41-9. 2007
    ..Our results support a need for comprehensive evaluation of COMT variations and their functional relevance as COMT may be an important molecular target to evaluate for new treatments regarding obesity...
  54. pmc Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium
    Todd M Gibson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20892, USA
    Cancer Causes Control 24:125-34. 2013
    ....
  55. pmc A pooled analysis of three studies evaluating genetic variation in innate immunity genes and non-Hodgkin lymphoma risk
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Br J Haematol 152:721-6. 2011
    ....
  56. pmc Adulthood residential ultraviolet radiation, sun sensitivity, dietary vitamin D, and risk of lymphoid malignancies in the California Teachers Study
    Ellen T Chang
    Cancer Prevention Institute of California, Fremont, CA, USA
    Blood 118:1591-9. 2011
    ..Dietary vitamin D also was not associated with risk of lymphoid malignancies. These results support a protective effect of routine residential UVR exposure against lymphomagenesis through mechanisms possibly independent of vitamin D...
  57. pmc Multiple human papillomavirus genotype infections in cervical cancer progression in the study to understand cervical cancer early endpoints and determinants
    Nicolas Wentzensen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7234, USA
    Int J Cancer 125:2151-8. 2009
    ..The potential range of HPV genotype attribution is wide at the disease categories <CIN2 to CIN3. Genotyping from cervical lesions and analyzing viral oncogene expression can improve estimates of HPV genotype attribution...
  58. pmc LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era
    James R Cerhan
    College of Medicine, Mayo Clinic, Rochester, MN, USA
    Leuk Lymphoma 53:1105-12. 2012
    ..In conclusion, germline genetic variation in LMO2 was associated with DLBCL prognosis and provided slightly stronger predictive ability relative to LMO2 IHC status...
  59. pmc Clinical and pathological heterogeneity of cervical intraepithelial neoplasia grade 3
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America
    PLoS ONE 7:e29051. 2012
    ..To improve our understanding of CIN3 natural history, we performed a detailed characterization of CIN3 heterogeneity in a large referral population in the US...
  60. pmc Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Blood 109:3479-88. 2007
    ..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
  61. pmc Joint effects between five identified risk variants, allergy, and autoimmune conditions on glioma risk
    Mahboobeh Safaeian
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Cancer Causes Control 24:1885-91. 2013
    ..Our results do not provide evidence that allergies or AIC modulate the association between the four GWAS-identified SNPs examined and risk of glioma...
  62. pmc Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era
    Thomas M Habermann
    Mayo Clinic College of Medicine, Rochester, MN, USA
    Blood 112:2694-702. 2008
    ..These data support a role for germ line variation in immune genes, particularly genes associated with a proinflammatory state, as predictors of late survival in DLBCL...
  63. doi request reprint Seroprevalence and correlates of human papillomavirus 16/18 seropositivity among young women in Costa Rica
    Sarah Coseo
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS, Room 7079, Rockville, MD 20852, USA
    Sex Transm Dis 37:706-14. 2010
    ..We investigated HPV16 and 18 seroepidemiology among young, unvaccinated women aged between 18 and 25...
  64. ncbi request reprint Mortality trends for cervical squamous and adenocarcinoma in the United States. Relation to incidence and survival
    Mark E Sherman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892 7374, USA
    Cancer 103:1258-64. 2005
    ..To make inferences about the effectiveness of screening, the authors assessed mortality trends for squamous and adenocarcinoma in relation to incidence of these tumors, incidence of their precursors and survival...
  65. pmc Inherited genetic variation and overall survival following follicular lymphoma
    Todd M Gibson
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Am J Hematol 87:724-6. 2012
    ..However, they require replication in independent populations, as well as assessment in rituximab-treated patients...
  66. ncbi request reprint DRD2 genetic variation in relation to smoking and obesity in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    Lindsay M Morton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Pharmacogenet Genomics 16:901-10. 2006
    ..To assess the specificity of genetic effects, we also investigated other reward-motivated characteristics (obesity, alcohol consumption)...
  67. pmc Oral contraceptives, menopausal hormone therapy use and risk of B-cell non-Hodgkin lymphoma in the California Teachers Study
    Yani Lu
    Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
    Int J Cancer 129:974-82. 2011
    ..15, 95% CI=1.62-6.13). Bilateral oophorectomy plus hysterectomy was not associated with risk among women who used ET or EPT. These results indicate that exogenous hormone use does not strongly influence B-cell NHL risk...
  68. pmc Cigarette smoking, passive smoking, and non-Hodgkin lymphoma risk: evidence from the California Teachers Study
    Yani Lu
    Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
    Am J Epidemiol 174:563-73. 2011
    ..89 (95% CI: 1.23, 6.80); P for trend = 0.01). The present study provides evidence that smoking and passive smoking may influence NHL etiology, particularly for follicular lymphoma...
  69. pmc Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
    Lucia Conde
    School of Public Health, University of California, Berkeley, Berkeley, California, USA
    Nat Genet 42:661-4. 2010
    ..We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 x 10(-9))...
  70. pmc Personal history of diabetes, genetic susceptibility to diabetes, and risk of brain glioma: a pooled analysis of observational studies
    Cari M Kitahara
    Authors Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda Core Genotyping Facility, National Cancer Institute, SAIC Frederick, Inc, Gaithersburg, Maryland Division of Cancer Etiology, Department of Population Sciences, City of Hope and the Beckman Research Institute, Duarte, California Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, Ohio Division of Preventive Medicine Division of Aging, Brigham and Women s Hospital, Harvard Medical School Massachusetts Veterans Epidemiology, Research and Information Center, Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, Massachusetts Fred Hutchinson Cancer Research Center Department of Epidemiology, University of Washington, Seattle, Washington Vanderbilt University Medical Center, Nashville, Tennessee Department of Radiation Sciences, Oncology, Umea University, Umeå and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 23:47-54. 2014
    ..Brain glioma is a relatively rare and fatal malignancy in adulthood with few known risk factors. Some observational studies have reported inverse associations between diabetes and subsequent glioma risk, but possible mechanisms are unclear...