Ricardo Spielberger

Summary

Affiliation: City of Hope National Medical Center
Country: USA

Publications

  1. ncbi request reprint Economic impact of palifermin on the costs of hospitalization for autologous hematopoietic stem-cell transplant: analysis of phase 3 trial results
    Linda S Elting
    Health Services Research, Department of Biostatistics, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Biol Blood Marrow Transplant 13:806-13. 2007
  2. pmc Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients
    Wendi Zhou
    Department of Virology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
    Blood 113:6465-76. 2009
  3. ncbi request reprint Palifermin for oral mucositis after intensive therapy for hematologic cancers
    Ricardo Spielberger
    City of Hope National Medical Center, Department of Hematology and Hematopoietic Cell Transplantation and Kaiser Permanente BMT Program, Duarte, Calif 91010, USA
    N Engl J Med 351:2590-8. 2004
  4. ncbi request reprint Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection
    Ghislaine Gallez-Hawkins
    Division of Virology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 11:890-902. 2005
  5. ncbi request reprint Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants
    Simon F Lacey
    Laboratory of Vaccine Research, Division of Virology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA
    Transplantation 74:722-32. 2002
  6. ncbi request reprint Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients
    Simon F Lacey
    Laboratory of Vaccine Research, Beckman Research Institute of the City of Hope, Duarte, California 91010 3000, USA
    J Infect Dis 191:977-84. 2005
  7. pmc A phase 1/2 trial of high-dose yttrium-90-ibritumomab tiuxetan in combination with high-dose etoposide and cyclophosphamide followed by autologous stem cell transplantation in patients with poor-risk or relapsed non-Hodgkin lymphoma
    Auayporn Nademanee
    Division of Hematology and Hemapoietic Cell Transplantation, City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA 91010, USA
    Blood 106:2896-902. 2005
  8. ncbi request reprint Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients
    Simon F Lacey
    Laboratory of Vaccine Research, Division of Information Sciences, Beckman Research Institute of the City of Hope, City of Hope Comprehensive Cancer Center, Duarte, CA 91010 3000, USA
    J Infect Dis 194:1410-21. 2006
  9. pmc CD154 expression is associated with neutralizing antibody titer levels postinfluenza vaccination in stem cell transplant patients and healthy adults
    Aprille Seidel
    Division of Translational Vaccine Research, Department of Virology, Beckman Research Institute of the City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Biol Blood Marrow Transplant 17:524-33. 2011
  10. pmc Total marrow irradiation: a new ablative regimen as part of tandem autologous stem cell transplantation for patients with multiple myeloma
    George Somlo
    Departments of Medical Oncology and Therapeutics Research, City of Hope Cancer Center, Duarte, California 91010, USA
    Clin Cancer Res 17:174-82. 2011

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Economic impact of palifermin on the costs of hospitalization for autologous hematopoietic stem-cell transplant: analysis of phase 3 trial results
    Linda S Elting
    Health Services Research, Department of Biostatistics, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Biol Blood Marrow Transplant 13:806-13. 2007
    ..In addition to its previously demonstrated clinical benefit, palifermin prophylaxis offers a favorable economic profile among patients with hematologic malignancies who receive total body irradiation and autologous stem cell support...
  2. pmc Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients
    Wendi Zhou
    Department of Virology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
    Blood 113:6465-76. 2009
    ..These results highlight the benefit of D(+) donors in improving outcomes of R(+) HCT recipients by reducing the duration and recurrent need of antiviral treatment, aided by increased levels of multifunctional CMV-specific T cells...
  3. ncbi request reprint Palifermin for oral mucositis after intensive therapy for hematologic cancers
    Ricardo Spielberger
    City of Hope National Medical Center, Department of Hematology and Hematopoietic Cell Transplantation and Kaiser Permanente BMT Program, Duarte, Calif 91010, USA
    N Engl J Med 351:2590-8. 2004
    ..We tested the ability of palifermin (recombinant human keratinocyte growth factor) to decrease oral mucosal injury induced by cytotoxic therapy...
  4. ncbi request reprint Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection
    Ghislaine Gallez-Hawkins
    Division of Virology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA
    Biol Blood Marrow Transplant 11:890-902. 2005
    ....
  5. ncbi request reprint Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants
    Simon F Lacey
    Laboratory of Vaccine Research, Division of Virology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA
    Transplantation 74:722-32. 2002
    ..CD8 T-lymphocytes have an important role in immunity against CMV, but correlation between antigen-specific subpopulations of these cells and protection are still unclear...
  6. ncbi request reprint Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients
    Simon F Lacey
    Laboratory of Vaccine Research, Beckman Research Institute of the City of Hope, Duarte, California 91010 3000, USA
    J Infect Dis 191:977-84. 2005
    ..These functional differences between T lymphocyte populations within the same individual may have implications for protection against CMV...
  7. pmc A phase 1/2 trial of high-dose yttrium-90-ibritumomab tiuxetan in combination with high-dose etoposide and cyclophosphamide followed by autologous stem cell transplantation in patients with poor-risk or relapsed non-Hodgkin lymphoma
    Auayporn Nademanee
    Division of Hematology and Hemapoietic Cell Transplantation, City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA 91010, USA
    Blood 106:2896-902. 2005
    ..We conclude that high-dose 90Y-ibritumomab tiuxetan can be combined safely with high-dose etoposide and cyclophosphamide without an increase in transplant-related toxicity or delayed engraftment...
  8. ncbi request reprint Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients
    Simon F Lacey
    Laboratory of Vaccine Research, Division of Information Sciences, Beckman Research Institute of the City of Hope, City of Hope Comprehensive Cancer Center, Duarte, CA 91010 3000, USA
    J Infect Dis 194:1410-21. 2006
    ..We also provide evidence of a relationship between cytotoxic function and the ability of cytomegalovirus-specific CTLs to secrete multiple cytokines...
  9. pmc CD154 expression is associated with neutralizing antibody titer levels postinfluenza vaccination in stem cell transplant patients and healthy adults
    Aprille Seidel
    Division of Translational Vaccine Research, Department of Virology, Beckman Research Institute of the City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Biol Blood Marrow Transplant 17:524-33. 2011
    ..A lack of B cell reconstitution and dysfunctional CD4 T cell costimulation (as marked by low CD154 expression) is associated with low NAb levels postvaccination in HCT patients...
  10. pmc Total marrow irradiation: a new ablative regimen as part of tandem autologous stem cell transplantation for patients with multiple myeloma
    George Somlo
    Departments of Medical Oncology and Therapeutics Research, City of Hope Cancer Center, Duarte, California 91010, USA
    Clin Cancer Res 17:174-82. 2011
    ..To establish feasibility, maximum tolerated dose (MTD), and potential efficacy of ablative dose total marrow irradiation (TMI) delivered by helical tomotherapy in patients with multiple myeloma (MM)...
  11. ncbi request reprint Current management of oral mucositis
    Ricardo Spielberger
    Department of Hematology, City of Hope National Medical Center, USA
    Clin Adv Hematol Oncol 3:769-71. 2005
  12. ncbi request reprint NCCN Task Force Report. prevention and management of mucositis in cancer care
    William Bensinger
    J Natl Compr Canc Netw 6:S1-21; quiz S22-4. 2008
    ..This report integrates expert judgment with a review of key literature on risk assessment, prevention, and treatment strategies, and provides recommendations for the overall management of OM...
  13. ncbi request reprint Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting
    Patrick J Stiff
    Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA
    J Clin Oncol 24:5186-93. 2006
    ....