David D Smith

Summary

Affiliation: City of Hope National Medical Center
Country: USA

Publications

  1. ncbi Evaluation of chronic lymphocytic leukemia by BAC-based microarray analysis
    Roger A Schultz
    Signature Genomics, 2820 N, Astor St, Spokane, WA, 99207, USA
    Mol Cytogenet 4:4. 2011
  2. ncbi Assessing karyotype precision by microarray-based comparative genomic hybridization in the myelodysplastic/myeloproliferative syndromes
    Marilyn L Slovak
    Signature Genomics, Spokane, WA, USA
    Mol Cytogenet 3:23. 2010
  3. ncbi Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation
    David D Smith
    Division of Molecular Medicine, City of Hope and Beckman Research Institute, Duarte, CA 91010, USA
    BMC Bioinformatics 9:63. 2008
  4. ncbi Predicting life expectancy and symptom relief following surgery for advanced malignancy
    David D Smith
    Department of Biostatistics, City of Hope National Medical Center, Duarte, CA 91010, USA
    Ann Surg Oncol 15:3335-41. 2008
  5. ncbi Median filter algorithm for estimating the threshold of detection on custom protein arrays
    David D Smith
    Department of Biostatistics, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA
    Biotechniques 41:74-8. 2006
  6. ncbi Colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2
    R Steven Esworthy
    Department of Cancer Biology, Beckman Research Institute of City of Hope, Duarte, California, USA
    Inflamm Bowel Dis 17:1373-86. 2011
  7. ncbi Dual DNA methylation patterns in the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes
    Jinhui Wang
    Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
    PLoS ONE 5:e13843. 2010
  8. ncbi Impact of graft cell dose on transplant outcomes following unrelated donor allogeneic peripheral blood stem cell transplantation: higher CD34+ cell doses are associated with decreased relapse rates
    Ryotaro Nakamura
    Division of Hematology Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 14:449-57. 2008
  9. ncbi Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to -7/del(7q) MDS
    Marilyn L Slovak
    Cytogenetics Laboratory, City of Hope, 1500 E Duarte Road, Duarte, CA 91010, USA
    Cancer Genet Cytogenet 193:78-85. 2009
  10. ncbi Paint-only is equivalent to scrub-and-paint in preoperative preparation of abdominal surgery sites
    Joshua D I Ellenhorn
    Division of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA
    J Am Coll Surg 201:737-41. 2005

Collaborators

Detail Information

Publications20

  1. ncbi Evaluation of chronic lymphocytic leukemia by BAC-based microarray analysis
    Roger A Schultz
    Signature Genomics, 2820 N, Astor St, Spokane, WA, 99207, USA
    Mol Cytogenet 4:4. 2011
    ..abstract:..
  2. ncbi Assessing karyotype precision by microarray-based comparative genomic hybridization in the myelodysplastic/myeloproliferative syndromes
    Marilyn L Slovak
    Signature Genomics, Spokane, WA, USA
    Mol Cytogenet 3:23. 2010
    ....
  3. ncbi Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation
    David D Smith
    Division of Molecular Medicine, City of Hope and Beckman Research Institute, Duarte, CA 91010, USA
    BMC Bioinformatics 9:63. 2008
    ..This allows one to compare expression data from a diverse collection of breast tumor array datasets generated on either cDNA or oligonucleotide arrays...
  4. ncbi Predicting life expectancy and symptom relief following surgery for advanced malignancy
    David D Smith
    Department of Biostatistics, City of Hope National Medical Center, Duarte, CA 91010, USA
    Ann Surg Oncol 15:3335-41. 2008
    ..We prospectively evaluated surgeons' ability to predict outcomes of life expectancy and symptom relief following major surgery for patients with advanced malignancies...
  5. ncbi Median filter algorithm for estimating the threshold of detection on custom protein arrays
    David D Smith
    Department of Biostatistics, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA
    Biotechniques 41:74-8. 2006
    ..This suggests that a median filter approach has utility in high-throughput arrays where visual inspection is impractical...
  6. ncbi Colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2
    R Steven Esworthy
    Department of Cancer Biology, Beckman Research Institute of City of Hope, Duarte, California, USA
    Inflamm Bowel Dis 17:1373-86. 2011
    ..The DKO mice on a B6 background have mild ileocolitis. We characterized the 129 DKO mice to identify a genetic locus affecting disease severity...
  7. ncbi Dual DNA methylation patterns in the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes
    Jinhui Wang
    Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
    PLoS ONE 5:e13843. 2010
    ..These results support the estimate that 1-2% of genes expressed in the CNS may be subject to allelic exclusion, and demonstrate that the group includes genes implicated in major disorders of the CNS as well as neurodevelopment...
  8. ncbi Impact of graft cell dose on transplant outcomes following unrelated donor allogeneic peripheral blood stem cell transplantation: higher CD34+ cell doses are associated with decreased relapse rates
    Ryotaro Nakamura
    Division of Hematology Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010 3000, USA
    Biol Blood Marrow Transplant 14:449-57. 2008
    ....
  9. ncbi Does MDS with der(1;7)(q10;p10) constitute a distinct risk group? A retrospective single institutional analysis of clinical/pathologic features compared to -7/del(7q) MDS
    Marilyn L Slovak
    Cytogenetics Laboratory, City of Hope, 1500 E Duarte Road, Duarte, CA 91010, USA
    Cancer Genet Cytogenet 193:78-85. 2009
    ..4, 32.0, and 23.6%, respectively) did not differ significantly (P=0.94). While der(1;7) MDS is associated with some clinically distinctive features, reassignment of risk category based on these data would be premature...
  10. ncbi Paint-only is equivalent to scrub-and-paint in preoperative preparation of abdominal surgery sites
    Joshua D I Ellenhorn
    Division of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA
    J Am Coll Surg 201:737-41. 2005
    ..This change will result in reductions in operative times and costs...
  11. ncbi Full-dose adjuvant postoperative radiation therapy for retroperitoneal sarcomas
    Richard D Pezner
    Department of Radiation Oncology, City of Hope Medical Center, Duarte, CA 91010, USA
    Am J Clin Oncol 34:511-6. 2011
    ..To categorize sites of recurrence of retroperitoneal sarcomas (RPS) and correlate to clinical treatment volumes of postoperative radiation therapy (PORT) with or without intraoperative radiation therapy (IORT)...
  12. ncbi Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma
    Marilyn L Slovak
    Cytogenetics Laboratory, Department of Hematology Stem Cell Transplantation, City of Hope, Duarte, California 91010, USA
    Clin Cancer Res 17:3443-54. 2011
    ..To determine the recurring DNA copy number alterations (CNA) in classical Hodgkin lymphoma (HL) by microarray-based comparative genomic hybridization (aCGH) using laser capture microdissected CD30(+) Hodgkin and Reed-Sternberg (HRS) cells...
  13. ncbi Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes
    Feng Miao
    Department of Diabetes, Beckman Research Institute of City of Hope, Duarte, CA, USA
    Diabetes 57:3189-98. 2008
    ....
  14. ncbi Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: a southwest oncology group study (S9431)
    Stephen R Moore
    City of Hope, Duarte, California 91010, USA
    Clin Cancer Res 14:2927-35. 2008
    ..The concordance between molecular cytogenetic techniques used to determine CNA has not been evaluated on a large set of loci in malignant melanoma...
  15. ncbi Survival in patients with papillary thyroid cancer is not affected by the use of radioactive isotope
    Yale D Podnos
    Department of General Oncologic Surgery, City of Hope National Medical Center, Duarte, California 91010, USA
    J Surg Oncol 96:3-7. 2007
    ..Its utility is controversial. This study seeks to determine whether RAI use affects patient outcome and to identify specific cohorts of patients that benefit from its use...
  16. ncbi Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase
    Qiang Gao
    Department of Radiation Biology, Beckman Research Institute of City of Hope, Duarte, California, USA
    Inflamm Bowel Dis 16:2043-54. 2010
    ..GPx1/2-double-knockout (DKO) mice deficient in 2 intracellular glutathione peroxidases, GPx1 and GPx2, on a C57BL/6 (B6) background, have mild ileocolitis on a conventional chow...
  17. ncbi The surgical treatment of cancer: a comparison of resource utilization following procedures performed with a curative and palliative intent
    Carey A Cullinane
    Department of General Oncologic Surgery, City of Hope National Medical Center, Duarte, California 91010, USA
    Cancer 98:2266-73. 2003
    ..The nature of the interactions, however, was different, suggesting that resource needs are different and may need to be anticipated in the assessment of how better quality outcomes can be achieved in the palliative surgery setting...
  18. ncbi Impact of intraoperative radiation on postoperative and disease-specific outcome after pancreatoduodenectomy for adenocarcinoma: a propensity score analysis
    Roderich E Schwarz
    City of Hope National Medical Center, Department of General Oncologic Surgery, Duarte, California, USA
    Am J Clin Oncol 26:16-21. 2003
    ..The recurrence pattern may be affected in some patients, but systemic recurrences predominate. We continue to explore IORT in combination with systemic chemotherapy...
  19. ncbi Challenges in array comparative genomic hybridization for the analysis of cancer samples
    Norma J Nowak
    New York State Center of Excellence in Bioinformatics and Life Sciences and Department of Biochemistry, University at Buffalo, Buffalo, New York 14203, USA
    Genet Med 9:585-95. 2007
    ....
  20. ncbi A comparison of cyclophosphamide and total body irradiation with etoposide and total body irradiation as conditioning regimens for patients undergoing sibling allografting for acute lymphoblastic leukemia in first or second complete remission
    David I Marks
    Adult BMT Unit, Bristol Children's Hospital, Bristol, UK
    Biol Blood Marrow Transplant 12:438-53. 2006
    ..We conclude that for HLA-identical sibling allografts for acute lymphoblastic leukemia in CR2, there is an advantage in substituting etoposide for Cy or, when Cy is used, in increasing the TBI dose to > or =13 Gy...